听力与言语-语言病理学

行为科学

医学伦理学

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  • 3D-printable zwitterionic nano-composite hydrogel system for biomedical applications.

    abstract::Herein, the cytotoxicity of a novel zwitterionic sulfobetaine hydrogel system with a nano-clay crosslinker has been investigated. We demonstrate that careful selection of the composition of the system (monomer to Laponite content) allows the material to be formed into controlled shapes using an extrusion based additiv...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731420967294

    authors: Sällström N,Capel A,Lewis MP,Engstrøm DS,Martin S

    更新日期:2020-10-29 00:00:00

  • Magnesium hydroxide-incorporated PLGA composite attenuates inflammation and promotes BMP2-induced bone formation in spinal fusion.

    abstract::Spinal fusion has become a common surgical technique to join two or more vertebrae to stabilize a damaged spine; however, the rate of pseudarthrosis (failure of fusion) is still high. To minimize pseudarthrosis, bone morphogenetic protein-2 (BMP2) has been approved for use in humans. In this study, we developed a poly...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731420967591

    authors: Bedair TM,Lee CK,Kim DS,Baek SW,Bedair HM,Joshi HP,Choi UY,Park KH,Park W,Han I,Han DK

    更新日期:2020-10-24 00:00:00

  • The combination of multi-functional ingredients-loaded hydrogels and three-dimensional printed porous titanium alloys for infective bone defect treatment.

    abstract::Biomaterial with the dual-functions of bone regeneration and antibacterial is a novel therapy for infective bone defects. Three-dimensional (3D)-printed porous titanium (pTi) benefits bone ingrowth, but its microporous structure conducive to bacteria reproduction. Herein, a multifunctional hydrogel was prepared from d...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731420965797

    authors: Qiao S,Wu D,Li Z,Zhu Y,Zhan F,Lai H,Gu Y

    更新日期:2020-10-23 00:00:00

  • A universal multi-platform 3D printed bioreactor chamber for tendon tissue engineering.

    abstract::A range of bioreactors use linear actuators to apply tensile forces in vitro, but differences in their culture environments can limit a direct comparison between studies. The widespread availability of 3D printing now provides an opportunity to develop a 'universal' bioreactor chamber that, with minimal exterior editi...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731420942462

    authors: Janvier AJ,Canty-Laird E,Henstock JR

    更新日期:2020-09-01 00:00:00

  • Prevention of excessive scar formation using nanofibrous meshes made of biodegradable elastomer poly(3-hydroxybutyrate-co-3-hydroxyvalerate).

    abstract::To reduce excessive scarring in wound healing, electrospun nanofibrous meshes, composed of haloarchaea-produced biodegradable elastomer poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), are fabricated for use as a wound dressing. Three PHBV polymers with different 3HV content are used to prepare either solution-cas...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731420949332

    authors: Kim HS,Chen J,Wu LP,Wu J,Xiang H,Leong KW,Han J

    更新日期:2020-08-23 00:00:00

  • Noninvasive measurement of cell/colony motion using image analysis methods to evaluate the proliferative capacity of oral keratinocytes as a tool for quality control in regenerative medicine.

    abstract::Image-based cell/colony analyses offer promising solutions to compensate for the lack of quality control (QC) tools for noninvasive monitoring of cultured cells, a regulatory challenge in regenerative medicine. Here, the feasibility of two image analysis algorithms, optical flow and normalised cross-correlation, to no...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731419881528

    authors: Hoshikawa E,Sato T,Kimori Y,Suzuki A,Haga K,Kato H,Tabeta K,Nanba D,Izumi K

    更新日期:2019-10-15 00:00:00

  • Insulin-like growth factor 1 stimulates the angiogenic activity of adipose tissue-derived microvascular fragments.

    abstract::Angiogenesis in adipose tissue is promoted by insulin-like growth factor 1 signaling. We analyzed whether this regulatory mechanism also improves the angiogenic activity of adipose tissue-derived microvascular fragments. Murine adipose tissue-derived microvascular fragments were cultivated for 24 h in the University o...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731419879837

    authors: Laschke MW,Kontaxi E,Scheuer C,Heß A,Karschnia P,Menger MD

    更新日期:2019-09-27 00:00:00

  • Mathematical and computational models for bone tissue engineering in bioreactor systems.

    abstract::Research into cellular engineered bone grafts offers a promising solution to problems associated with the currently used auto- and allografts. Bioreactor systems can facilitate the development of functional cellular bone grafts by augmenting mass transport through media convection and shear flow-induced mechanical sti...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731419827922

    authors: Burova I,Wall I,Shipley RJ

    更新日期:2019-02-22 00:00:00

  • Reformulated mineral trioxide aggregate components and the assessments for use as future dental regenerative cements.

    abstract::Mineral trioxide aggregate, which comprises three major inorganic components, namely, tricalcium silicate (C3S), dicalcium silicate (C2S), and tricalcium aluminate (C3A), is promising regenerative cement for dentistry. While mineral trioxide aggregate has been successfully applied in retrograde filling, the exact role...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731418807396

    authors: Moon HJ,Lee JH,Kim JH,Knowles JC,Cho YB,Shin DH,Lee HH,Kim HW

    更新日期:2018-10-30 00:00:00

  • Osteoblast response to disordered nanotopography.

    abstract::The ability to influence stem cell differentiation is highly desirable as it would help us improve clinical outcomes for patients in various aspects. Many different techniques to achieve this have previously been investigated. This concise study, however, has focused on the topography on which cells grow. Current unce...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731418784098

    authors: Allan C,Ker A,Smith CA,Tsimbouri PM,Borsoi J,O'Neill S,Gadegaard N,Dalby MJ,Dominic Meek RM

    更新日期:2018-07-11 00:00:00

  • Engineering a microcirculation for perfusion control of ex vivo-assembled organ systems: Challenges and opportunities.

    abstract::Donor organ shortage remains a clear problem for many end-stage organ patients around the world. The number of available donor organs pales in comparison with the number of patients in need of these organs. The field of tissue engineering proposes a plausible solution. Using stem cells, a patient's autologous cells, o...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章,评审

    doi:10.1177/2041731418772949

    authors: Kottamasu P,Herman I

    更新日期:2018-05-10 00:00:00

  • Three-dimensional Printing in Maxillofacial Surgery: Hype versus Reality.

    abstract::Three-dimensional printing technology is getting more attention recently, especially in the craniofacial region. This is a review of literature enlightening the materials that have been used to date and the application of such technology within the scope of maxillofacial surgery. ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731418770909

    authors: Aldaadaa A,Owji N,Knowles J

    更新日期:2018-04-20 00:00:00

  • Extended bioreactor conditioning of mononuclear cell-seeded heart valve scaffolds.

    abstract::The tissue-engineered heart valve may be the ideal valve replacement option but still must overcome challenges in leaflet recellularization. This study sought to investigate the potential for leaflet matrix restoration and repopulation following mononuclear cell seeding and extended periods of bioreactor conditioning....

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731418767216

    authors: VeDepo M,Buse E,Quinn R,Hopkins R,Converse G

    更新日期:2018-04-10 00:00:00

  • Methacrylated gelatin/hyaluronan-based hydrogels for soft tissue engineering.

    abstract::In vitro-generated soft tissue could provide alternate therapies for soft tissue defects. The aim of this study was to evaluate methacrylated gelatin/hyaluronan as scaffolds for soft tissue engineering and their interaction with human adipose-derived stem cells (hASCs). ASCs were incorporated into methacrylated gelati...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731417744157

    authors: Kessler L,Gehrke S,Winnefeld M,Huber B,Hoch E,Walter T,Wyrwa R,Schnabelrauch M,Schmidt M,Kückelhaus M,Lehnhardt M,Hirsch T,Jacobsen F

    更新日期:2017-12-21 00:00:00

  • Controlled dexamethasone delivery via double-walled microspheres to enhance long-term adipose tissue retention.

    abstract::Current materials used for adipose tissue reconstruction have critical shortcomings such as suboptimal volume retention, donor-site morbidity, and poor biocompatibility. The aim of this study was to examine a controlled delivery system of dexamethasone to generate stable adipose tissue when mixed with disaggregated hu...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731417735402

    authors: Kelmendi-Doko A,Rubin JP,Klett K,Mahoney C,Wang S,Marra KG

    更新日期:2017-10-09 00:00:00

  • Recellularization of decellularized heart valves: Progress toward the tissue-engineered heart valve.

    abstract::The tissue-engineered heart valve portends a new era in the field of valve replacement. Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart valve due to their naturally bioactive composition, clinical relevance as a stand-alone implant, and partial recellularization in vivo....

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章,评审

    doi:10.1177/2041731417726327

    authors: VeDepo MC,Detamore MS,Hopkins RA,Converse GL

    更新日期:2017-08-25 00:00:00

  • Development and characterisation of a low-concentration sodium dodecyl sulphate decellularised porcine dermis.

    abstract::The aim of this study was to adapt a proprietary decellularisation process for human dermis for use with porcine skin. Porcine skin was subject to: sodium chloride (1 M) to detach the epidermis, trypsin paste to remove hair follicles, peracetic acid (0.1% v/v) disinfection, washed in hypotonic buffer and 0.1% (w/v) so...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731417724011

    authors: Helliwell JA,Thomas DS,Papathanasiou V,Homer-Vanniasinkam S,Desai A,Jennings LM,Rooney P,Kearney JN,Ingham E

    更新日期:2017-08-03 00:00:00

  • Tri-layered composite plug for the repair of osteochondral defects: in vivo study in sheep.

    abstract::Cartilage defects are a source of pain, immobility, and reduced quality of life for patients who have acquired these defects through injury, wear, or disease. The avascular nature of cartilage tissue adds to the complexity of cartilage tissue repair or regeneration efforts. The known limitations of using autografts, a...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731417697500

    authors: Yucekul A,Ozdil D,Kutlu NH,Erdemli E,Aydin HM,Doral MN

    更新日期:2017-04-13 00:00:00

  • Human platelet-rich plasma improves the nesting and differentiation of human chondrocytes cultured in stabilized porous chitosan scaffolds.

    abstract::The clinical management of large-size cartilage lesions is difficult due to the limited regenerative ability of the cartilage. Different biomaterials have been used to develop tissue engineering substitutes for cartilage repair, including chitosan alone or in combination with growth factors to improve its chondrogenic...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731417697545

    authors: Sancho-Tello M,Martorell S,Mata Roig M,Milián L,Gámiz-González MA,Gómez Ribelles JL,Carda C

    更新日期:2017-03-23 00:00:00

  • Optimal conjugation of catechol group onto hyaluronic acid in coronary stent substrate coating for the prevention of restenosis.

    abstract::Although endovascular stenting has been used as an interventional therapy to treat cardio- and cerebro-vascular diseases, it is associated with recurrent vascular diseases following stent thrombosis and in-stent restenosis. In this study, a metallic stent was coated with dopamine-conjugated hyaluronic acid with differ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731416683745

    authors: Lih E,Choi SG,Ahn DJ,Joung YK,Han DK

    更新日期:2016-12-17 00:00:00

  • Clinical safety and efficacy of implantation of octacalcium phosphate collagen composites in tooth extraction sockets and cyst holes.

    abstract::It was demonstrated that octacalcium phosphate collagen composite achieved notable bone regeneration in bone defects in preclinical studies. On the basis of the research results, an investigator-initiated exploratory clinical trial was conducted after approval from a local Institutional Review Board. This clinical stu...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731416670770

    authors: Kawai T,Tanuma Y,Matsui K,Suzuki O,Takahashi T,Kamakura S

    更新日期:2016-10-03 00:00:00

  • Erythropoietin stimulation of human adipose tissue for therapeutic refilling releases protective cytokines.

    abstract::Apoptosis and inflammatory processes may be at the basis of reducing graft survival. Erythropoietin is a tissue-protective hormone with pleiotropic potential, and it interferes with the activities of pro-inflammatory cytokines and stimulates healing following injury, preventing destruction of tissue surrounding the in...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731416671278

    authors: Sabbatini M,Bosetti M,Borrone A,Moalem L,Taveggia A,Verna G,Cannas M

    更新日期:2016-09-27 00:00:00

  • A recapitulative three-dimensional model of breast carcinoma requires perfusion for multi-week growth.

    abstract::Breast carcinomas are complex, three-dimensional tissues composed of cancer epithelial cells and stromal components, including fibroblasts and extracellular matrix. In vitro models that more faithfully recapitulate this dimensionality and stromal microenvironment should more accurately elucidate the processes driving ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731416660739

    authors: Goliwas KF,Marshall LE,Ransaw EL,Berry JL,Frost AR

    更新日期:2016-07-29 00:00:00

  • Therapeutic transdifferentiation of human fibroblasts into endothelial cells using forced expression of lineage-specific transcription factors.

    abstract::Transdifferentiation is the direct conversion from one somatic cell type into another desired somatic cell type. This reprogramming method offers an attractive approach for regenerative medicine. Here, we demonstrate that neonatal fibroblasts can be transdifferentiated into endothelial cells using only four endothelia...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731416628329

    authors: Wong WT,Cooke JP

    更新日期:2016-02-01 00:00:00

  • Antibody-mediated inhibition of Nogo-A signaling promotes neurite growth in PC-12 cells.

    abstract::The use of a monoclonal antibody to block the neurite outgrowth inhibitor Nogo-A has been of great interest for promoting axonal recovery as a treatment for spinal cord injury. While several cellular and non-cellular assays have been developed to quantify the bioactive effects of Nogo-A signaling, demand still exists ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731416629767

    authors: Yazdi IK,Taghipour N,Hmaidan S,Palomba R,Scaria S,Munoz A,Boone TB,Tasciotti E

    更新日期:2016-01-28 00:00:00

  • Pulsed low-intensity ultrasound increases proliferation and extracelluar matrix production by human dermal fibroblasts in three-dimensional culture.

    abstract::This study evaluated the effect of pulsed low-intensity ultrasound on cell proliferation, collagen production and glycosaminoglycan deposition by human dermal fibroblasts encapsulated in alginate. Hoechst 33258 assay for cell number, hydroxyproline assay for collagen content, dimethylmethylene blue assay for glycosami...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731415615777

    authors: Bohari SP,Grover LM,Hukins DW

    更新日期:2015-11-19 00:00:00

  • Growth factor and ultrasound-assisted bioreactor synergism for human mesenchymal stem cell chondrogenesis.

    abstract::Ultrasound at 5.0 MHz was noted to be chondro-inductive, with improved SOX-9 gene and COL2A1 protein expression in constructs that allowed for cell-to-cell contact. To achieve tissue-engineered cartilage using macroporous scaffolds, it is hypothesized that a combination of ultrasound at 5.0 MHz and transforming growth...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731414566529

    authors: Guha Thakurta S,Budhiraja G,Subramanian A

    更新日期:2015-01-16 00:00:00

  • A review on the use of cell therapy in the treatment of tendon disease and injuries.

    abstract::Tendon disease and injuries carry significant morbidity worldwide in both athletic and non-athletic populations. It is estimated that tendon injuries account for 30%-50% of all musculoskeletal injuries globally. Current treatments have been inadequate in providing an accelerated process of repair resulting in high rel...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章,评审

    doi:10.1177/2041731414549678

    authors: Ho JO,Sawadkar P,Mudera V

    更新日期:2014-09-18 00:00:00

  • Calcium phosphate thin films enhance the response of human mesenchymal stem cells to nanostructured titanium surfaces.

    abstract::The development of biomaterial surfaces possessing the topographical cues that can promote mesenchymal stem cell recruitment and, in particular, those capable of subsequently directing osteogenic differentiation is of increasing importance for the advancement of tissue engineering. While it is accepted that it is the ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731414537513

    authors: McCafferty MM,Burke GA,Meenan BJ

    更新日期:2014-05-27 00:00:00

  • Uniaxial cyclic strain of human adipose-derived mesenchymal stem cells and C2C12 myoblasts in coculture.

    abstract::Tissue engineering skeletal muscle in vitro is of great importance for the production of tissue-like constructs for treating tissue loss due to traumatic injury or surgery. However, it is essential to find new sources of cells for muscle engineering as efficient in vitro expansion and culture of primary myoblasts are ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731414530138

    authors: Dugan JM,Cartmell SH,Gough JE

    更新日期:2014-03-27 00:00:00

  • Application of stem-cell media to explant culture of human periosteum: An optimal approach for preparing osteogenic cell material.

    abstract::As part of our clinical tests on bone regeneration using cultured periosteal sheets, here, we prepared cultured periosteal sheets in two types of stem-cell culture media, STK1 and STK3. Human periosteum was expanded either in 1% human serum-supplemented STK1 for 28 days, in 1% human serum-supplemented STK1 for 14 days...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731413509646

    authors: Uematsu K,Nagata M,Kawase T,Suzuki K,Takagi R

    更新日期:2013-10-23 00:00:00

  • Short-term in vivo biological and mechanical remodeling of porcine acellular dermal matrices.

    abstract::The purpose of this study was to assess the biological revitalization and mechanical integrity of Strattice(™) Reconstructive Tissue Matrix, a porcine-derived acellular dermal matrix, in vivo over time. We expanded the traditional subcutaneous model to incorporate biologic matrix scaffolds large enough to allow evalua...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.1177/2041731413490182

    authors: Monteiro GA,Rodriguez NL,Delossantos AI,Wagner CT

    更新日期:2013-05-17 00:00:00

  • A modified porous titanium sheet prepared by plasma-activated sintering for biomedical applications.

    abstract::This study aimed to develop a contamination-free porous titanium scaffold by a plasma-activated sintering within an originally developed TiN-coated graphite mold. The surface of porous titanium sheet with or without a coated graphite mold was characterized. The cell adhesion property of porous titanium sheet was also ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.4061/2010/425402

    authors: Tamaki Y,Lee WS,Kataoka Y,Miyazaki T

    更新日期:2011-01-09 00:00:00

  • Nanotopographical control of stem cell differentiation.

    abstract::Stem cells have the capacity to differentiate into various lineages, and the ability to reliably direct stem cell fate determination would have tremendous potential for basic research and clinical therapy. Nanotopography provides a useful tool for guiding differentiation, as the features are more durable than surface ...

    journal_title:Journal of tissue engineering

    pub_type: 杂志文章

    doi:10.4061/2010/120623

    authors: McNamara LE,McMurray RJ,Biggs MJ,Kantawong F,Oreffo RO,Dalby MJ

    更新日期:2010-08-18 00:00:00