abstract：:Enlargement of the mitral valve (MV) has gained attention as a compensatory mechanism for functional mitral regurgitation (FMR). We aimed to determine if MV leaflet area is associated with MV coaptation-zone area and identify the clinical factors associated with MV leaflet size and coaptation-zone area in patients wit...

journal_title：International heart journal

authors： Xu B,Daimon M,Kawata T,Nakao T,Hirokawa M,Sawada N,Kimura K,Yamanaka Y,Morita H,Komuro I,Yatomi Y

更新日期：2021-01-16 00:00:00

abstract：:A 14 year-old boy developed infective endocarditis of the mitral valve caused by Methicillin-sensitive Staphylococcus aureus and became comatose. Isolated basilar artery dissection was initially observed on the 3rd day by magnetic resonance imaging (MRI), ie, it did not exist on day 1. He underwent successful urgent m...

journal_title：International heart journal

authors： Kawano A,Masutani S,Inui A,Honma H,Igarashi T,Tsuneoka H,Sakamoto W,Sakurai Y,Dembo T,Imanaka K

更新日期：2021-01-16 00:00:00

abstract：:Various surgical techniques have been proposed for treating aortic arch aneurysm (AAA); however, the optimal treatment has not been well defined. This study introduces a new aortic arch inclusion technique with frozen elephant trunk (FET) for AAA treatment.A retrospective analysis was performed among 22 patients for A...

journal_title：International heart journal

authors： Zhu C,Piao H,Wang Y,Li B,Zhang Y,Xu J,Wang T,Zhu Z,Xu R,Li D,Liu K

更新日期：2020-11-28 00:00:00

abstract：:The long-term prognosis for up to 20 years of patients who have undergone percutaneous transvenous mitral commissurotomy (PTMC) for mitral stenosis (MS) is unknown.We examined 77 of 93 patients (83%) with MS and who underwent PTMC from 1989 to 2002 at our institute, as well as the occurrence of either one of the follo...

journal_title：International heart journal

authors： Kubota N,Ozaki K,Hoyano M,Nishida K,Takano T,Okubo T,Kimura S,Yanagawa T,Kashimura T,Minamino T

更新日期：2020-11-28 00:00:00

abstract：:After the new left ventricular ejection fraction (LVEF) classification criteria emerged, many studies have focused on the differences between heart failure (HF) with reduced EF (HFrEF), HF with midrange EF (HFmrEF), and HF with preserved EF (HFpEF). However, the lack of consensus on sex-related differences in prognosi...

journal_title：International heart journal

authors： Wang C,Zhou Y,Zhong R,Bao Y,Li Z,Tian J

更新日期：2020-11-28 00:00:00

abstract：:Our study aimed to investigate whether the frame design of transcatheter heart valve (THV) affects the procedural and clinical results of transcatheter aortic valve implantation (TAVI).We retrospectively reviewed 163 patients with aortic stenosis who underwent TAVI using different types of THV (Edwards SAPIEN, n = 31;...

journal_title：International heart journal

authors： Li F,Wang X,Wang Y,Li X,Xu D,Zhao S,Wang C,Guo Y,Wu Y,Wang W

更新日期：2020-11-28 00:00:00

abstract：:There is little data on management and outcomes of atrial fibrillation (AF) patients on direct oral anticoagulants (DOAC) undergoing general surgery.We retrospectively assessed 98 surgeries in 85 nonvalvular AF patients aged 73 ± 8 (59 men) receiving DOACs. Cardiac, emergency, and minimally invasive surgeries were exc...

journal_title：International heart journal

authors： Kawabata M,Goya M,Maeda S,Yagishita A,Takahashi Y,Sasano T,Hirao K

更新日期：2020-09-29 00:00:00

abstract：:The incidence of ventricular arrhythmia in patients with an implanted pacemaker is not yet known. The aim of this study was to analyze non-sustained ventricular tachycardia (NSVT) episodes based on stored electrograms (EGM) and determine the occurrence rate and risk factors for NSVT in a pacemaker population.This stud...

journal_title：International heart journal

authors： Hosoda J,Ishikawa T,Matsumoto K,Kiyokuni M,Taguchi Y,Narikawa M,Hibi K,Sugano T,Ishigami T,Tamura K,Kimura K

更新日期：2020-09-29 00:00:00

abstract：:The aim of this meta-analysis was to compare the clinical outcomes in patients who underwent rapid deployment aortic valve replacement (RDAVR) and conventional bio prosthetic aortic valve replacement (CAVR).We performed a literature search by August 2018. The primary outcomes were hospital and 1-year mortality, and th...

journal_title：International heart journal

authors： Lu Y,Wang J,Chen Z,Wei J,Li F,Cai Z

更新日期：2020-09-29 00:00:00

abstract：:Ventricular free wall rupture (FWR) is a catastrophic complication of that occurs after acute myocardial infarction (AMI), and at present, its clinical characteristics are unclear. We analyzed a total of 6,712 consecutive patients who presented with ST-segment elevation myocardial infarction (STEMI), and 78 patients w...

journal_title：International heart journal

authors： Gong W,Shi H,Yan M,Yan Y,Wang X,Li S,He X,Nie S

更新日期：2020-07-30 00:00:00

abstract：:The metabolism of branched-chain amino acids (BCAAs) is reported to change in heart failure (HF) and correlate with cardiac function. However, the effect of BCAAs on HF remains controversial. We investigate the prognostic value of the plasma BCAA level in nonischemic dilated cardiomyopathy (NIDCM).This study enrolled ...

journal_title：International heart journal

authors： Kimura Y,Okumura T,Kazama S,Shibata N,Oishi H,Arao Y,Kuwayama T,Kato H,Yamaguchi S,Hiraiwa H,Kondo T,Morimoto R,Murohara T

更新日期：2020-07-30 00:00:00

abstract：:Acute coronary syndrome (ACS) can develop in patients with mildly to moderately stenotic lesions. However, the angiographic characteristics of lesions in patients who will later develop ACS have not been systematically investigated. For this reason, we examined the earlier angiographic findings of such patients in a r...

journal_title：International heart journal

authors： Yamaya S,Morino Y,Taguchi Y,Ninomiya R,Ishida M,Fusazaki T,Itoh T,Kimura T

更新日期：2020-05-30 00:00:00

abstract：:Many published studies have evaluated the association between the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) polymorphism and the risk of congenital heart disease (CHD); however, the specific conclusion is still controversial.To get a more accurate conclusion, we used a meta-analysis to evaluat...

journal_title：International heart journal

authors： Liu PF,Ding B,Zhang JY,Mei XF,Li F,Wu P,Mei CH,Zhou YF,Chen T

更新日期：2020-05-30 00:00:00

abstract：:We experienced a 33-year-old patient with D-looped transposition of the great arteries (D-TGA) and a history of Senning operation who was referred to our institute with cardiogenic shock and subsequently underwent urgent paracorporeal ventricular assist device (VAD) implantation, which was a first in Japan, that was e...

journal_title：International heart journal

authors： Nakamura M,Imamura T,Kuwahara H,Nakagaito M,Yokoyama S,Doi T,Fukahara K,Yoshimura N,Kinugawa K

更新日期：2020-05-30 00:00:00

abstract：:Myocardial infarction (MI) is one of the major causes of death worldwide, and the therapeutic strategies of MI are still limited. In this study, we investigated the function of miR-665 in MI. In the present study, an ischemia/reperfusion (I/R) rat model and a hypoxia/reoxygenation (H/R)-induced H9c2 cell model were su...

journal_title：International heart journal

authors： Liu C,Tang M,Zhang X,Li J,Cao G

更新日期：2020-03-28 00:00:00

abstract：:Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...

journal_title：International heart journal

authors： Jin B,Ji F,Zuo A,Liu H,Qi L,He Y,Wang Q,Zhao P

更新日期：2020-03-28 00:00:00

abstract：:Despite its clinical relevance, a subclass of acute decompensated heart failure (ADHF) with elevated blood pressure, known as hypertensive ADHF (HT-ADHF), has been less intensively evaluated. This study aimed to characterize the prognostic nature and pathophysiology of HT-ADHF. A total of 509 consecutive patients with...

journal_title：International heart journal

authors： Hiki M,Iwata H,Takasu K,Nojiri S,Ishikawa G,Chikata Y,C Mattson P,Kasai T,Miyazaki T,Inoue K,Fujiwara Y,Sumiyoshi M,Kinugawa K,Daida H

更新日期：2020-03-28 00:00:00

abstract：:Coronary collateral circulation (CCC) plays a crucial role in myocardial blood supply, especially for ischemic myocardium. Previous study has shown that neuregulin-1 is a prominent angiogenic factor in diabetic cardiomyopathy, whereas the relationship between neuregulin-1 and CCC has not been investigated. Thus, we ai...

journal_title：International heart journal

authors： Huang M,Zheng J,Chen Z,You C,Huang Q

更新日期：2020-01-31 00:00:00

abstract：:This study aimed to evaluate whether the heart is the target organ of endogenous atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in patients with heart failure (HF) with reduced ejection fraction (HFrEF).We measured the plasma levels of cyclic guanosine monophosphate (cGMP), which is a second mess...

journal_title：International heart journal

authors： Tsutamoto T,Sakai H,Yamamoto T,Nakagawa Y

更新日期：2020-01-31 00:00:00

abstract：:Exercise preconditioning may protect against cardiac injury induced by lipopolysaccharide (LPS), but the mechanism is unresolved. The aim of this study is to explore whether the general control nonderepressible 2 (GCN2) kinase gene is associated with the protective effect of exercise preconditioning. Eight-week-old ma...

journal_title：International heart journal

authors： Sun ZG,Lu G,Zhao LL,Zhang LZ,Li A,Jing J,Xu X

更新日期：2020-01-31 00:00:00

abstract：:Therapeutic strategies for pulmonary arterial hypertension (PAH) have made remarkable progress over the last two decades. Currently, 3 types of drugs can be used to treat PAH; prostacyclins, phosphodiesterase 5 inhibitors, and endothelin receptor antagonists (ERA). In Japan, the first generation ERA bosentan was reimb...

journal_title：International heart journal

authors： Maki H,Hara T,Tsuji M,Saito A,Minatsuki S,Inaba T,Amiya E,Hosoya Y,Hatano M,Morita H,Yao A,Kinugawa K,Komuro I

更新日期：2020-01-01 00:00:00

abstract：:Low-density lipoprotein (LDL) particles are known to be atherogenic agents in coronary artery diseases. They adjust to other electronegative forms and can be the subject for the enhancement of inflammatory events in vessel subendothelial spaces. The LDL uptake is related to the membrane scavenger receptors, including ...

journal_title：International heart journal

authors： Li Y,Rao Y,Zhu H,Jiang B,Zhu M

更新日期：2020-01-01 00:00:00

abstract：:Although atrial ischemic damage is an atrial fibrillation (AF) risk factor, the impact of atrial branches' occlusion on AF development after acute myocardial infarction (AMI) is unclear. Therefore, this study's purpose was to identify predictors of new-onset AF with regard to atrial branches' occlusion. We retrospecti...

journal_title：International heart journal

authors： Shiba T,Kondo Y,Senoo K,Nakano M,Okubo K,Ishio N,Shikama N,Kobayashi Y

更新日期：2019-11-30 00:00:00

abstract：:In order to prevent ischemic stroke, it is important to identify and treat patients with atrial fibrillation (AF) who do not consult a doctor in a medical institution. The aim of this study was to determine the consultation rate at medical institutions for patients with AF in group medical examinations conducted in a ...

journal_title：International heart journal

authors： Matsumi H,Nakamura K,Eguchi E,Miyoshi T,Nakagawa K,Nishii N,Watanabe A,Ueoka A,Yoshida M,Tokunaga N,Amioka N,Yamada N,Saito D,Morita H,Ogino K,Ito H,Ibara-AF Investigators.

更新日期：2019-11-30 00:00:00

abstract：:Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to inv...

journal_title：International heart journal

authors： Aoyama D,Miyazaki S,Hasegawa K,Kaseno K,Ishikawa E,Mukai M,Miyahara K,Aiki T,Matsui A,Yamaguchi J,Shiomi Y,Tama N,Ikeda H,Fukuoka Y,Morishita T,Ishida K,Uzui H,Tada H

更新日期：2019-11-30 00:00:00

abstract：:We report the case of a 79-year-old man with acute myocardial infarction caused by left main trunk lesion, who experienced cardiogenic shock during percutaneous coronary intervention (PCI). To reverse the cardiogenic shock, we initiated veno-arterial extra corporeal membrane oxygenation (VA-ECMO) without an intra-aort...

journal_title：International heart journal

authors： Kaneko D,Takahashi M,Fukutomi M,Funayama H,Kario K

更新日期：2019-09-27 00:00:00

abstract：:Plaque erosion (PE) is a significant substrate of acute coronary thrombosis. An improved ability to distinguish plaque phenotype in vivo among patients with ST-segment elevation myocardial infarction (STEMI) is of considerable interest because of the potential to formulate tailored treatment. This study assessed the p...

journal_title：International heart journal

authors： Dong H,Hu S,Sun R,Wang C,Dai J,Pan W,Xing L,Liu X,Wu J,Liu J,Jia H,Yu B

更新日期：2019-09-27 00:00:00

abstract：:The literature on malignant cardiac tumors is relatively limited because they are rare, especially among the Chinese population. We analyzed 14 patients diagnosed with malignant cardiac tumors in Fuwai Hospital and present the results of surgical treatments on the tumors. The mean age at tumor diagnosis was 47 years i...

journal_title：International heart journal

authors： Guo GR,Wang X,Yang J,Chen L,Song JP,Wang LQ

更新日期：2019-07-27 00:00:00

abstract：:Myocardial infarction (MI) occurs when the heart muscle is severely damaged due to a decrease in blood flow from the coronary arteries. During recovery from an MI, cardiac fibroblasts become activated and produce extracellular matrices, contributing to the wound healing process in the damaged heart. Inappropriate acti...

journal_title：International heart journal

authors： Wake M,Takeda N,Isagawa T,Sato T,Nakagama Y,Morioka MS,Hirota Y,Asagiri M,Maemura K,Manabe I,Tanabe K,Komuro I

更新日期：2019-07-27 00:00:00

abstract：:Tenascin-C (TNC) is involved in aortic disease pathophysiology. This study aims to evaluate TNC's value for predicting in-hospital death in acute aortic dissection (AD).We prospectively enrolled consecutive patients with suspected acute AD within 48 hours from symptom onset. Serum TNC and C-reactive protein (CRP) leve...

journal_title：International heart journal

authors： Guo T,Zhou X,Zhu A,Peng W,Zhong Y,Chai X

更新日期：2019-07-27 00:00:00

abstract：:The clinical scenario, which is based on systolic blood pressure (SBP) upon admission, is useful for classifying and determining initial treatment for acute heart failure (HF). However, the prognostic significance of SBP following the initial treatment is unclear.The Japanese Heart Failure Syndrome with Preserved Ejec...

journal_title：International heart journal

authors： Sato Y,Yoshihisa A,Oikawa M,Nagai T,Yoshikawa T,Saito Y,Yamamoto K,Takeishi Y,Anzai T

更新日期：2019-07-27 00:00:00

abstract：:The association between endothelial function, evaluated using flow-mediated dilatation (FMD), and the severity of coronary artery disease remains to be elucidated.A total of 245 consecutive patients with stable angina were prospectively enrolled. FMD was evaluated in the brachial artery before percutaneous coronary in...

journal_title：International heart journal

authors： Nemoto T,Minami Y,Yamaoka-Tojo M,Sato T,Muramatsu Y,Kakizaki R,Fujiyoshi K,Hashimoto T,Meguro K,Shimohama T,Tojo T,Ako J

更新日期：2019-05-30 00:00:00

abstract：:Mechanical heart valve replacement (MHVR) entails lifetime oral anticoagulation to eliminate thrombosis. However, adverse events may still occur despite proper anticoagulation therapy. In this study, we investigated whether D-dimer can predict the clinical events in post-MHVR patients during oral anticoagulation thera...

journal_title：International heart journal

authors： Zhang L,Long Y,Xiao H,Yang J,Liu X,Zhang Z

更新日期：2019-05-30 00:00:00

abstract：:Apelin was proved to attenuate cardiac interstitial fibrosis. However, the association between apelin level and myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) is still unclear.This study aims to determine whether apelin is associated with myocardial fibrosis in HCM and investigate the predictiv...

journal_title：International heart journal

authors： Zhou Y,Yuan J,Wang Y,Qiao S

更新日期：2019-05-30 00:00:00

abstract：:Multivessel disease (MVD) is an independent risk factor for poor prognosis in acute myocardial infarction patients. Although several global risk scoring systems (RSS) are in use in clinical practice, there is no dedicated RSS for MVD in ST-segment elevation myocardial infarction (STEMI). The primary objective of this ...

journal_title：International heart journal

authors： Ryu KS,Bae JW,Jeong MH,Cho MC,Ryu KH,and other Korea Acute Myocardial Infarction Registry Investigators.

更新日期：2019-05-30 00:00:00

abstract：:Cognitive behavioral therapy has emerged as an important approach to alleviate the depression of patients with heart failure. However, the use of cognitive behavioral therapy for heart failure has not been well established. We conduct a systematic review and meta-analysis to evaluate the efficacy of cognitive behavior...

journal_title：International heart journal

authors： Peng Y,Fang J,Huang W,Qin S

更新日期：2019-05-30 00:00:00

abstract：:Flexible, in vivo maneuverable electrophysiology mapping techniques are not available in rat models. A novel cardiac stereotactic electrophysiology epicardial mapping system (CREAMS) allows for various measurements, including: (1) recording unipolar electrograms at multiple sites; (2) positioning of mapped sites and p...

journal_title：International heart journal

authors： Fan B,Wang H,Wu T,Li Y,Lin Z,Li M,Li Q,Zhang W,Zheng Q

更新日期：2019-03-20 00:00:00

abstract：:Atrial fibrillation has caused severe burden for people worldwide. Differentiation of fibroblasts into myofibroblasts, and consequent progress in atrial structural remodeling have been considered the basis for persistent atrial fibrillation, yet little is known about the molecular mechanisms underlying the process. He...

journal_title：International heart journal

authors： Sai C,Yunhan J,Zhao J,Yu Z,Yun Z,Zhezhe C,Fuqin T,Yingbin X,Ruiyan M

更新日期：2019-03-20 00:00:00

abstract：:Patients with ischemic heart disease are associated with poor prognosis, and their number has increased globally. Therefore, biomarkers that could predict post-acute myocardial infarction (AMI) heart failure (HF) would be helpful to guide appropriate treatment. Based on the diagnosis on admission and results of echoca...

journal_title：International heart journal

authors： Lin X,Zhang S,Huo Z

更新日期：2019-03-20 00:00:00

abstract：:A 65-year-old Japanese man complaining of general malaise and presenting with high fever was admitted to our hospital. He had untreated diabetes and hepatocellular carcinoma with liver cirrhosis. Overall findings of the patient indicated sepsis. Two blood cultures were positive for Streptococcus dysgalactiae, a group ...

journal_title：International heart journal

authors： Takahashi F,Wada Y,Hasebe N

更新日期：2019-01-25 00:00:00