解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Enlargement of the mitral valve (MV) has gained attention as a compensatory mechanism for functional mitral regurgitation (FMR). We aimed to determine if MV leaflet area is associated with MV coaptation-zone area and identify the clinical factors associated with MV leaflet size and coaptation-zone area in patients wit...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-148
更新日期:2021-01-16 00:00:00
abstract::A 14 year-old boy developed infective endocarditis of the mitral valve caused by Methicillin-sensitive Staphylococcus aureus and became comatose. Isolated basilar artery dissection was initially observed on the 3rd day by magnetic resonance imaging (MRI), ie, it did not exist on day 1. He underwent successful urgent m...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-474
更新日期:2021-01-16 00:00:00
abstract::Various surgical techniques have been proposed for treating aortic arch aneurysm (AAA); however, the optimal treatment has not been well defined. This study introduces a new aortic arch inclusion technique with frozen elephant trunk (FET) for AAA treatment.A retrospective analysis was performed among 22 patients for A...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-069
更新日期:2020-11-28 00:00:00
abstract::The long-term prognosis for up to 20 years of patients who have undergone percutaneous transvenous mitral commissurotomy (PTMC) for mitral stenosis (MS) is unknown.We examined 77 of 93 patients (83%) with MS and who underwent PTMC from 1989 to 2002 at our institute, as well as the occurrence of either one of the follo...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-082
更新日期:2020-11-28 00:00:00
abstract::After the new left ventricular ejection fraction (LVEF) classification criteria emerged, many studies have focused on the differences between heart failure (HF) with reduced EF (HFrEF), HF with midrange EF (HFmrEF), and HF with preserved EF (HFpEF). However, the lack of consensus on sex-related differences in prognosi...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-321
更新日期:2020-11-28 00:00:00
abstract::Our study aimed to investigate whether the frame design of transcatheter heart valve (THV) affects the procedural and clinical results of transcatheter aortic valve implantation (TAVI).We retrospectively reviewed 163 patients with aortic stenosis who underwent TAVI using different types of THV (Edwards SAPIEN, n = 31;...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-398
更新日期:2020-11-28 00:00:00
abstract::There is little data on management and outcomes of atrial fibrillation (AF) patients on direct oral anticoagulants (DOAC) undergoing general surgery.We retrospectively assessed 98 surgeries in 85 nonvalvular AF patients aged 73 ± 8 (59 men) receiving DOACs. Cardiac, emergency, and minimally invasive surgeries were exc...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-625
更新日期:2020-09-29 00:00:00
abstract::The incidence of ventricular arrhythmia in patients with an implanted pacemaker is not yet known. The aim of this study was to analyze non-sustained ventricular tachycardia (NSVT) episodes based on stored electrograms (EGM) and determine the occurrence rate and risk factors for NSVT in a pacemaker population.This stud...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-141
更新日期:2020-09-29 00:00:00
abstract::The aim of this meta-analysis was to compare the clinical outcomes in patients who underwent rapid deployment aortic valve replacement (RDAVR) and conventional bio prosthetic aortic valve replacement (CAVR).We performed a literature search by August 2018. The primary outcomes were hospital and 1-year mortality, and th...
journal_title:International heart journal
pub_type: 杂志文章,meta分析
doi:10.1536/ihj.19-717
更新日期:2020-09-29 00:00:00
abstract::Ventricular free wall rupture (FWR) is a catastrophic complication of that occurs after acute myocardial infarction (AMI), and at present, its clinical characteristics are unclear. We analyzed a total of 6,712 consecutive patients who presented with ST-segment elevation myocardial infarction (STEMI), and 78 patients w...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-541
更新日期:2020-07-30 00:00:00
abstract::The metabolism of branched-chain amino acids (BCAAs) is reported to change in heart failure (HF) and correlate with cardiac function. However, the effect of BCAAs on HF remains controversial. We investigate the prognostic value of the plasma BCAA level in nonischemic dilated cardiomyopathy (NIDCM).This study enrolled ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-010
更新日期:2020-07-30 00:00:00
abstract::Acute coronary syndrome (ACS) can develop in patients with mildly to moderately stenotic lesions. However, the angiographic characteristics of lesions in patients who will later develop ACS have not been systematically investigated. For this reason, we examined the earlier angiographic findings of such patients in a r...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-601
更新日期:2020-05-30 00:00:00
abstract::Many published studies have evaluated the association between the 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) polymorphism and the risk of congenital heart disease (CHD); however, the specific conclusion is still controversial.To get a more accurate conclusion, we used a meta-analysis to evaluat...
journal_title:International heart journal
pub_type: 杂志文章,meta分析
doi:10.1536/ihj.19-389
更新日期:2020-05-30 00:00:00
abstract::We experienced a 33-year-old patient with D-looped transposition of the great arteries (D-TGA) and a history of Senning operation who was referred to our institute with cardiogenic shock and subsequently underwent urgent paracorporeal ventricular assist device (VAD) implantation, which was a first in Japan, that was e...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-670
更新日期:2020-05-30 00:00:00
abstract::Myocardial infarction (MI) is one of the major causes of death worldwide, and the therapeutic strategies of MI are still limited. In this study, we investigated the function of miR-665 in MI. In the present study, an ischemia/reperfusion (I/R) rat model and a hypoxia/reoxygenation (H/R)-induced H9c2 cell model were su...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-416
更新日期:2020-03-28 00:00:00
abstract::Heart failure (HF) is a disease with high morbidity and mortality. In patients with HF, decreased cardiac output and blood redistribution results in decreased intestinal perfusion and destruction of intestinal barrier. Microorganisms and endotoxins can migrate into the blood circulation, aggravating systemic inflammat...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-372
更新日期:2020-03-28 00:00:00
abstract::Despite its clinical relevance, a subclass of acute decompensated heart failure (ADHF) with elevated blood pressure, known as hypertensive ADHF (HT-ADHF), has been less intensively evaluated. This study aimed to characterize the prognostic nature and pathophysiology of HT-ADHF. A total of 509 consecutive patients with...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-521
更新日期:2020-03-28 00:00:00
abstract::Coronary collateral circulation (CCC) plays a crucial role in myocardial blood supply, especially for ischemic myocardium. Previous study has shown that neuregulin-1 is a prominent angiogenic factor in diabetic cardiomyopathy, whereas the relationship between neuregulin-1 and CCC has not been investigated. Thus, we ai...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-277
更新日期:2020-01-31 00:00:00
abstract::This study aimed to evaluate whether the heart is the target organ of endogenous atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in patients with heart failure (HF) with reduced ejection fraction (HFrEF).We measured the plasma levels of cyclic guanosine monophosphate (cGMP), which is a second mess...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-379
更新日期:2020-01-31 00:00:00
abstract::Exercise preconditioning may protect against cardiac injury induced by lipopolysaccharide (LPS), but the mechanism is unresolved. The aim of this study is to explore whether the general control nonderepressible 2 (GCN2) kinase gene is associated with the protective effect of exercise preconditioning. Eight-week-old ma...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-307
更新日期:2020-01-31 00:00:00
abstract::Therapeutic strategies for pulmonary arterial hypertension (PAH) have made remarkable progress over the last two decades. Currently, 3 types of drugs can be used to treat PAH; prostacyclins, phosphodiesterase 5 inhibitors, and endothelin receptor antagonists (ERA). In Japan, the first generation ERA bosentan was reimb...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-173
更新日期:2020-01-01 00:00:00
abstract::Low-density lipoprotein (LDL) particles are known to be atherogenic agents in coronary artery diseases. They adjust to other electronegative forms and can be the subject for the enhancement of inflammatory events in vessel subendothelial spaces. The LDL uptake is related to the membrane scavenger receptors, including ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.20-043
更新日期:2020-01-01 00:00:00
abstract::Although atrial ischemic damage is an atrial fibrillation (AF) risk factor, the impact of atrial branches' occlusion on AF development after acute myocardial infarction (AMI) is unclear. Therefore, this study's purpose was to identify predictors of new-onset AF with regard to atrial branches' occlusion. We retrospecti...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-713
更新日期:2019-11-30 00:00:00
abstract::In order to prevent ischemic stroke, it is important to identify and treat patients with atrial fibrillation (AF) who do not consult a doctor in a medical institution. The aim of this study was to determine the consultation rate at medical institutions for patients with AF in group medical examinations conducted in a ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-062
更新日期:2019-11-30 00:00:00
abstract::Uninterrupted anticoagulation therapy during atrial fibrillation (AF) ablation minimizes the risk of periprocedural thromboembolic events. Although the use of direct oral anticoagulants (DOACs) has rapidly developed in patients undergoing AF ablation, no antidote is available for factor Xa inhibitors. We sought to inv...
journal_title:International heart journal
pub_type: 临床试验,杂志文章
doi:10.1536/ihj.19-143
更新日期:2019-11-30 00:00:00
abstract::We report the case of a 79-year-old man with acute myocardial infarction caused by left main trunk lesion, who experienced cardiogenic shock during percutaneous coronary intervention (PCI). To reverse the cardiogenic shock, we initiated veno-arterial extra corporeal membrane oxygenation (VA-ECMO) without an intra-aort...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-643
更新日期:2019-09-27 00:00:00
abstract::Plaque erosion (PE) is a significant substrate of acute coronary thrombosis. An improved ability to distinguish plaque phenotype in vivo among patients with ST-segment elevation myocardial infarction (STEMI) is of considerable interest because of the potential to formulate tailored treatment. This study assessed the p...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.19-014
更新日期:2019-09-27 00:00:00
abstract::The literature on malignant cardiac tumors is relatively limited because they are rare, especially among the Chinese population. We analyzed 14 patients diagnosed with malignant cardiac tumors in Fuwai Hospital and present the results of surgical treatments on the tumors. The mean age at tumor diagnosis was 47 years i...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-269
更新日期:2019-07-27 00:00:00
abstract::Myocardial infarction (MI) occurs when the heart muscle is severely damaged due to a decrease in blood flow from the coronary arteries. During recovery from an MI, cardiac fibroblasts become activated and produce extracellular matrices, contributing to the wound healing process in the damaged heart. Inappropriate acti...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-710
更新日期:2019-07-27 00:00:00
abstract::Tenascin-C (TNC) is involved in aortic disease pathophysiology. This study aims to evaluate TNC's value for predicting in-hospital death in acute aortic dissection (AD).We prospectively enrolled consecutive patients with suspected acute AD within 48 hours from symptom onset. Serum TNC and C-reactive protein (CRP) leve...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-462
更新日期:2019-07-27 00:00:00
abstract::The clinical scenario, which is based on systolic blood pressure (SBP) upon admission, is useful for classifying and determining initial treatment for acute heart failure (HF). However, the prognostic significance of SBP following the initial treatment is unclear.The Japanese Heart Failure Syndrome with Preserved Ejec...
journal_title:International heart journal
pub_type: 杂志文章,多中心研究
doi:10.1536/ihj.18-699
更新日期:2019-07-27 00:00:00
abstract::The association between endothelial function, evaluated using flow-mediated dilatation (FMD), and the severity of coronary artery disease remains to be elucidated.A total of 245 consecutive patients with stable angina were prospectively enrolled. FMD was evaluated in the brachial artery before percutaneous coronary in...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-531
更新日期:2019-05-30 00:00:00
abstract::Mechanical heart valve replacement (MHVR) entails lifetime oral anticoagulation to eliminate thrombosis. However, adverse events may still occur despite proper anticoagulation therapy. In this study, we investigated whether D-dimer can predict the clinical events in post-MHVR patients during oral anticoagulation thera...
journal_title:International heart journal
pub_type: 临床试验,杂志文章
doi:10.1536/ihj.18-237
更新日期:2019-05-30 00:00:00
abstract::Apelin was proved to attenuate cardiac interstitial fibrosis. However, the association between apelin level and myocardial fibrosis in patients with hypertrophic cardiomyopathy (HCM) is still unclear.This study aims to determine whether apelin is associated with myocardial fibrosis in HCM and investigate the predictiv...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-598
更新日期:2019-05-30 00:00:00
abstract::Multivessel disease (MVD) is an independent risk factor for poor prognosis in acute myocardial infarction patients. Although several global risk scoring systems (RSS) are in use in clinical practice, there is no dedicated RSS for MVD in ST-segment elevation myocardial infarction (STEMI). The primary objective of this ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.17-337
更新日期:2019-05-30 00:00:00
abstract::Cognitive behavioral therapy has emerged as an important approach to alleviate the depression of patients with heart failure. However, the use of cognitive behavioral therapy for heart failure has not been well established. We conduct a systematic review and meta-analysis to evaluate the efficacy of cognitive behavior...
journal_title:International heart journal
pub_type: 杂志文章,meta分析
doi:10.1536/ihj.18-408
更新日期:2019-05-30 00:00:00
abstract::Flexible, in vivo maneuverable electrophysiology mapping techniques are not available in rat models. A novel cardiac stereotactic electrophysiology epicardial mapping system (CREAMS) allows for various measurements, including: (1) recording unipolar electrograms at multiple sites; (2) positioning of mapped sites and p...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-215
更新日期:2019-03-20 00:00:00
abstract::Atrial fibrillation has caused severe burden for people worldwide. Differentiation of fibroblasts into myofibroblasts, and consequent progress in atrial structural remodeling have been considered the basis for persistent atrial fibrillation, yet little is known about the molecular mechanisms underlying the process. He...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-073
更新日期:2019-03-20 00:00:00
abstract::Patients with ischemic heart disease are associated with poor prognosis, and their number has increased globally. Therefore, biomarkers that could predict post-acute myocardial infarction (AMI) heart failure (HF) would be helpful to guide appropriate treatment. Based on the diagnosis on admission and results of echoca...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.18-306
更新日期:2019-03-20 00:00:00
abstract::A 65-year-old Japanese man complaining of general malaise and presenting with high fever was admitted to our hospital. He had untreated diabetes and hepatocellular carcinoma with liver cirrhosis. Overall findings of the patient indicated sepsis. Two blood cultures were positive for Streptococcus dysgalactiae, a group ...
journal_title:International heart journal
pub_type: 杂志文章
doi:10.1536/ihj.17-700
更新日期:2019-01-25 00:00:00