解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:PURPOSE OF REVIEW:Research has consistently shown that type 2 diabetes (T2D) is associated with increased risk of all-cause dementia. Because one of the most common clinical presentations of early stage dementia is memory impairment, we examined the relationship of T2D with memory function, using the recently published...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01085-9
更新日期:2020-11-05 00:00:00
abstract:PURPOSE OF REVIEW:The surgical management of trauma-related intracranial hemorrhage is characterized by marked heterogeneity. Large prospective randomized trials have generally been prohibited by the ubiquity of concordant pathology, diversity of trauma systems, and paucity of clinical equipoise among providers. RECEN...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01080-0
更新日期:2020-11-02 00:00:00
abstract:PURPOSE OF REVIEW:Coronavirus disease 2019 (COVID-19) has become a global health crisis of our time. The disease arises from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that binds to angiotensin-converting enzyme 2 (ACE2) receptors on host cells for its internalization. COVID-19 has a wide range of res...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01079-7
更新日期:2020-10-30 00:00:00
abstract:PURPOSE OF REVIEW:To review the peripheral neurological complications of the acute hepatic porphyrias, as well as the latest advances in their pathophysiology and management. RECENT FINDINGS:The diagnosis of porphyric neuropathy remains challenging as varying neuropathic patterns are encountered depending on disease s...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01078-8
更新日期:2020-10-07 00:00:00
abstract:PURPOSE OF REVIEW:We describe the pervasiveness of headache diseases across the globe and the need for healthcare advocacy, define healthcare advocacy, and identify how providers can incorporate healthcare advocacy into clinical practice and beyond. RECENT FINDINGS:Nearly 3 billion people across the globe experience m...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01073-z
更新日期:2020-09-17 00:00:00
abstract:PURPOSE OF REVIEW:Seizures can arise in neocortical, thalamocortical, limbic or brainstem networks. Here, we review recent genetic mechanisms implicated in focal and genetic generalized epilepsies (GGEs). RECENT FINDINGS:Pathogenic variation in GAP activity toward RAGs 1 (GATOR1) complex genes (i.e., DEPDC5, NPRL2 and...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01059-x
更新日期:2020-08-13 00:00:00
abstract:PURPOSE OF REVIEW:Despite the increase in the number of novel antiseizure medications over the past 20 years, approximately one-third of patients will not have adequate seizure control on medications. For these patients, additional options need to be considered, including dietary, device, and surgical treatments. In ad...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01061-3
更新日期:2020-07-09 00:00:00
abstract:PURPOSE OF REVIEW:Elevated cholesterol is an established risk factor for ischemic stroke. The value of statins for stroke prevention has been clear for more than a decade. RECENT FINDINGS:However, the use of new medication combinations such as ezetimibe or proprotein convertase subtilisin-kexin type 9 inhibitors plus ...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01052-4
更新日期:2020-06-22 00:00:00
abstract:PURPOSE OF REVIEW:This review overviews perioperative stroke as it pertains to specific surgical procedures. RECENT FINDINGS:As awareness of perioperative stroke increases, so does the opportunity to potentially improve outcomes for these patients by early stroke recognition and intervention. Perioperative stroke is d...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-01033-7
更新日期:2020-04-27 00:00:00
abstract:PURPOSE OF REVIEW:Transcranial magnetic stimulation (TMS) is a method of Non-Invasive Brain Stimulation that is based on electro-physical principles discovered by Michael Faraday. A TMS device is made of one or two copper coils, positioned superficially to a site of interest in the brain, to non-invasively produce a br...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-020-1021-0
更新日期:2020-02-04 00:00:00
abstract:PURPOSE OF REVIEW:Diagnostic classification of patients with disorders of consciousness (DoC) is based on clinician's observation of volitional behaviours. However, patients' caregivers often report higher levels of responsiveness with respect to those observed during the clinical assessment. Thus, increasing efforts h...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章
doi:10.1007/s11910-019-1018-8
更新日期:2019-11-26 00:00:00
abstract:PURPOSE OF REVIEW:The optimal management of external ventricular drains (EVD) in the setting of acute brain injury remains controversial. Therefore, we sought to determine whether there are optimal management approaches based on the current evidence. RECENT FINDINGS:We identified 2 recent retrospective studies on the ...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-1009-9
更新日期:2019-11-26 00:00:00
abstract:PURPOSE OF REVIEW:We aim to evaluate the epidemiology, racial and gender disparity, etiology, and treatment of stroke in the younger population. RECENT FINDINGS:The younger age group without vascular risk factors exhibits an increased prevalence of cardio-embolism in context of patent foramen ovale/atrial septal aneur...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-1004-1
更新日期:2019-11-25 00:00:00
abstract:PURPOSE OF REVIEW:Neurogenic stunned myocardium (NSM) is a poorly recognized cardiac manifestation of neurological illness. This review addresses the contemporary understanding of NSM pathophysiology, epidemiology, diagnosis, and clinical management. RECENT FINDINGS:While the precise pathophysiology and diagnosis rema...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0999-7
更新日期:2019-11-13 00:00:00
abstract:PURPOSE OF REVIEW:This chapter focuses on limb apraxia, a cognitive-motor disorder of learned skilled movement, and the nature of the spatiotemporal errors that disrupt movement sequences. RECENT FINDINGS:A cognitive model that attempts to reconcile conceptual and preparatory aspects of the motor program with perceptu...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0989-9
更新日期:2019-11-12 00:00:00
abstract:PURPOSE OF REVIEW:Until recently, the gene associated with the recessive form of familial brain calcification (PFBC, Fahr disease) was unknown. MYORG, a gene that causes recessive PFBC was only recently discovered and is currently the only gene associated with a recessive form of this disease. Here, we review the radio...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0986-z
更新日期:2019-08-23 00:00:00
abstract:PURPOSE OF REVIEW:Near-death experiences (NDEs) are conscious perceptual experiences, including self-related emotional, spiritual, and mystical experiences, occurring in close encounters with death or in non-life-threatening situations. The origin of NDEs remains unknown. Here, we review recent advances in the understa...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0983-2
更新日期:2019-07-27 00:00:00
abstract:PURPOSE OF REVIEW:Type 2 diabetes (T2D) is a well-established risk factor for the development of dementia. Dementia and T2D share some underlying pathophysiology that has led to interest in the potential to repurpose drugs used in the management of T2D to benefit brain health. This review describes the scientific data ...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0973-4
更新日期:2019-07-12 00:00:00
abstract:PURPOSE OF REVIEW:Abnormal accumulation of tau protein is the main hallmark of tauopathies and is closely associated with neurodegeneration and cognitive impairment, whereas the advance in PET imaging provides a non-invasive detection of tau inclusions in the brain. In this review, we discuss the potential of PET imagi...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0962-7
更新日期:2019-06-06 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this study was to review recent literature on the early secondary prevention in transient ischemic attack (TIA) and minor stroke. RECENT FINDINGS:The result of Clopidogrel in High-Risk Patients with Acute Nondisabling Cerebrovascular Events and the secondary analysis of Platelet-Orient...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0950-y
更新日期:2019-05-14 00:00:00
abstract:PURPOSE OF REVIEW:The usefulness of the Wada test (WT) predicting memory impairment from temporal lobe epilepsy (TLE) surgery has been debated, and it has progressively been replaced by functional MRI (fMRI). We review the current role of WT and fMRI in the presurgical assessment of TLE, and how novel surgical techniqu...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0945-8
更新日期:2019-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Occipital neuralgia (ON) and cervicogenic headache (CGH) are secondary headache disorders with occipital pain as a key feature. Due to significant phenotypic overlap, differentiating ON and CGH from primary headache disorders such as migraine or tension-type headache, or other secondary headache disor...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0937-8
更新日期:2019-03-19 00:00:00
abstract:PURPOSE OF REVIEW:To update the current knowledge concerning sleep complaints and breathing disorders in myotonic dystrophy type 2 (DM2) and to better understand if sleep and breathing symptoms may add a further clinical definition of DM2. RECENT FINDINGS:Although DM2 has been poorly evaluated, the most relevant sleep...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0924-0
更新日期:2019-02-09 00:00:00
abstract:PURPOSE OF REVIEW:Idiopathic REM sleep behavior disorder (iRBD) is one of the most significant prodromal manifestations of synucleinopathies. Different predictive biomarkers for iRBD conversion have been investigated, but scarce data are present in literature about the predictive role of cerebrospinal fluid (CSF) bioma...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0918-y
更新日期:2019-01-14 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this review is to summarize current conceptual models of cognitive reserve (CR) and related concepts and to discuss evidence for these concepts within the context of aging and Alzheimer's disease. RECENT FINDINGS:Evidence to date supports the notion that higher levels of CR, as measured by...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-019-0917-z
更新日期:2019-01-09 00:00:00
abstract:PURPOSE OF REVIEW:To update current knowledge regarding sleep disturbances and myotonic dystrophies so as to better understand if sleep symptoms may help in the early recognition of the two genetic subtypes: myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2). RECENT FINDINGS:Sleep-disordered breathing...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0903-x
更新日期:2018-10-31 00:00:00
abstract:PURPOSE OF REVIEW:In this review, we summarize current knowledge and hypotheses on the nature of social abnormalities in autism spectrum disorder (ASD) and Williams syndrome (WS). RECENT FINDINGS:Social phenotypes in ASD and WS appear to reflect analogous disruptions in social cognition, and distinct patterns of socia...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0902-y
更新日期:2018-10-17 00:00:00
abstract:PURPOSE OF REVIEW:Parkinson's disease was studied for a long time from the prism of a motor impairment. Recent advances have outlined the importance of cognitive and neuropsychiatric symptoms (NPS) in the PD equation. This review concentrates on the present possibilities of using neuroimaging techniques in order to qua...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0907-6
更新日期:2018-10-15 00:00:00
abstract:PURPOSE OF REVIEW:Our purpose is to review evidence relating to the concept that interictal epileptiform discharges (IEDs) impair brain performance. RECENT FINDINGS:Sophisticated measures of motor and cognitive performance have clarified older observations, confirming that in both animals and humans, IEDs affect aspec...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0892-9
更新日期:2018-10-08 00:00:00
abstract:PURPOSE OF REVIEW:Measurements obtained during real-world activity by wearable motion sensors may contribute more naturalistic accounts of clinically meaningful changes in impairment, activity, and participation during neurologic rehabilitation, but obstacles persist. Here we review the basics of wearable sensors, the ...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0896-5
更新日期:2018-10-06 00:00:00
abstract:PURPOSE OF REVIEW:Patients with Parkinson's disease (PD) often display gastrointestinal and genitourinary autonomic symptoms years or even decades prior to diagnosis. These symptoms are thought to be caused in part by pathological α-synuclein inclusions in the peripheral autonomic and enteric nervous systems. It has be...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0889-4
更新日期:2018-09-19 00:00:00
abstract:PURPOSE OF THE REVIEW:The aims of fluid management in acute brain injury are to preserve or restore physiology and guarantee appropriate tissue perfusion, avoiding potential iatrogenic effects. We reviewed the literature, focusing on the clinical implications of the selected papers. Our purposes were to summarize the p...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0885-8
更新日期:2018-09-11 00:00:00
abstract:PURPOSE OF REVIEW:Sleep-wake disorders (SWD) are common not only in the general population but also in stroke patients, in whom SWD may be pre-existent or appear "de novo" as a consequence of brain damage. Despite increasing evidence of a negative impact of SWD on cardiocerebrovascular risk, cognitive functions, and qu...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0879-6
更新日期:2018-09-07 00:00:00
abstract:PURPOSE OF REVIEW:Hiccups are a common problem that crosses multiple disciplines including neurology, gastroenterology and pulmonology, and primary care. There are no formal guidelines to the treatment of intractable hiccups and treatment is based on experience and anecdotal evidence often relying on older medications....
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0856-0
更新日期:2018-06-22 00:00:00
abstract:PURPOSE OF REVIEW:Clinical trials using agents directed at neuroprotection and remyelination in multiple sclerosis (MS) are needed. As optic neuritis (ON) is common in people with MS and the pathology of ON is similar to other MS lesions in the brain, measurements of the anterior visual system are frequently utilized i...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0858-y
更新日期:2018-06-19 00:00:00
abstract:PURPOSE OF REVIEW:GBA mutations are the most common known genetic cause of Parkinson's disease (PD). Its biological pathway may be important in idiopathic PD, since activity of the enzyme encoded by GBA, glucocerebrosidase, is reduced even among PD patients without GBA mutations. This article describes the structure an...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0860-4
更新日期:2018-06-08 00:00:00
abstract:PURPOSE OF REVIEW:Memory is one of the top concerns of epilepsy patients, but there are no known treatments to directly alleviate the memory deficits associated with epilepsy. Neurostimulation may provide new therapeutic tools to enhance memory in epilepsy patients. Here, we critically review recent investigations of m...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0837-3
更新日期:2018-04-19 00:00:00
abstract:PURPOSE OF REVIEW:Parkinson's disease (PD) is a complex neurodegenerative disorder, the aetiology of which is still largely unknown. Overwhelming evidence indicates that mitochondrial dysfunction is a central factor in PD pathophysiology. Here we review recent developments around mitochondrial dysfunction in familial a...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0829-3
更新日期:2018-04-03 00:00:00
abstract:PURPOSE OF REVIEW:The proportion to which genetic and environmental factors contribute to the etiology of multiple sclerosis (MS) is still incompletely understood. An interesting association between MS etiology and obesity has recently been shown although the mechanisms underlying this association are still unknown. We...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,评审
doi:10.1007/s11910-018-0827-5
更新日期:2018-03-10 00:00:00
abstract::The original version of this article contains an error in the second sentence of the second paragraph of the Paleolithic Diet section. ...
journal_title:Current neurology and neuroscience reports
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11910-017-0804-4
更新日期:2017-10-17 00:00:00