abstract：:The noradrenergic locus coeruleus nucleus is an important station in both the ascending and descending pain regulatory pathways. These neurons discharge in tonic and phasic modes in response to sensory stimuli. However, few studies have set out to characterize the electrophysiological response of the locus coeruleus t...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Alba-Delgado C,Mico JA,Berrocoso E

更新日期：2021-03-08 00:00:00

abstract：:The efficacy and tolerability of repetitive transcranial magnetic stimulation (rTMS) in major depression is well-known and documented by existing studies. However, whether rTMS may be effective on suicidal behavior is unclear and needs to be further investigated. This systematic review is aimed to investigate the avai...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Serafini G,Canepa G,Aguglia A,Amerio A,Bianchi D,Magnani L,Dell'Osso B,Pompili M,Fitzgerald PB,Amore M

更新日期：2021-03-08 00:00:00

abstract：:In neurofeedback applications, neural activity is recorded, processed in real-time and fed back to the user in order to facilitate self-regulation of the putative neural mechanisms that underlie cognition and behavior. Numerous studies suggest that neurofeedback interventions are an efficacious treatment particularly ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Schönenberg M,Weingärtner AL,Weimer K,Scheeff J

更新日期：2021-03-08 00:00:00

abstract：:The brain's endocannabinoid system plays a crucial role in reward processes by mediating appetitive learning and encoding the reinforcing properties of substances. Evidence also suggests that endocannabinoids are an important constituent of neuronal substrates involved in emotional responses to stress. Thus, it is cri...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Filbey FM,Beaton D,Prashad S

更新日期：2021-03-02 00:00:00

abstract：:Low grade neuroinflammation has been suggested as one of the underlying mechanisms of many psychiatric diseases as well as cognitive disorders. Interleukin 8 (IL-8), a proinflammatory cytokine produced by many cell types including macrophage and microglia, mainly functions as a neutrophil chemoattractant in the bloods...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Tsai SJ

更新日期：2021-03-02 00:00:00

abstract：:During the COVID-19, healthcare workers are exposed to a higher risk of mental health problems, especially anxiety symptoms. The current work aims at contributing to an update of anxiety prevalence in this population by conducting a rapid systematic review and meta-analysis. Medline and Pubmed were searched for studie...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Santabárbara J,Bueno-Notivol J,Lipnicki DM,Olaya B,Pérez-Moreno M,Gracia-García P,Idoiaga-Mondragon N,Ozamiz-Etxebarria N

更新日期：2021-01-14 00:00:00

abstract：:Postpartum depression occurs in 10-15% of mothers. Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that plays a role in neuroplasticity. We hypothesized that the concentration of BDNF is related to reproduction and childbirth, and that women with postpartum depression show alteration in BDNF level. A...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lee Y,Kim KH,Lee BH,Kim YK

更新日期：2021-01-11 00:00:00

abstract：:The neurodevelopmental hypothesis of schizophrenia has been widely accepted. In light of our previous microarray data, two neurodevelopment-related genes were focused on inclduing the N-acylsphingosine amidohydrolase 1 gene (ASAH1) and the nerve growth factor gene (NGF). The evidence that ASAH1 and NGF are associated ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Su Y,Yang L,Li Z,Wang W,Xing M,Fang Y,Cheng Y,Lin GN,Cui D

更新日期：2021-01-10 00:00:00

abstract：BACKGROUND:The cognitive and emotional vulnerability of individuals with social anxiety disorder (SAD) and their response to repeated experiences of social rejection and social acceptance are important factors for the emergence and maintenance of symptoms of the disorder. Functional neuroimaging studies of SAD reveal h...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Kir Y,Sayar-Akaslan D,Agtas-Ertan E,Kusman A,Baskak N,Baran Z,Munir K,Baskak B

更新日期：2021-01-10 00:00:00

abstract：:Numerous pharmacological treatments for mood disorders are currently available; however, rates of treatment resistance, relapse and recurrence remain high. Therefore, novel treatments acting outside of the conventionally targeted monoamine system are urgently needed to improve patient outcomes. Emerging and converging...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Siegel AN,Rodrigues N,Nasri F,Wilkialis L,Lipsitz O,Lee Y,Gill H,Subramaniapillai M,Phan L,Majeed A,Lui LMW,Rashidian H,Ho R,Toma S,Goldstein BI,Mansur RB,McIntyre RS,Rosenblat JD

更新日期：2021-01-10 00:00:00

abstract：:Recent neuroimaging studies have characterized the pathophysiology of late-life depression (LLD) as a dysfunction of the brain networks involved in the regulation of emotion, motivational behavior, cognitive control, executive function, and self-referential thinking. In this article, we reviewed LLD-associated structu...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Kim YK,Han KM

更新日期：2021-01-10 00:00:00

abstract：:The COVID-19 pandemic has had far-ranging consequences for general physical and mental health. Country-specific research reveals a general reduction in mental and physical well-being, due to measures undertaken to stop the spread of COVID-19 disease. However, research is yet to examine the impact of the pandemic on gl...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Varma P,Junge M,Meaklim H,Jackson ML

更新日期：2020-12-26 00:00:00

abstract：:Researchers have made considerable progress in elucidating psychological and exercise correlates of major depressive disorder (MDD). However, as the largest immune organ, far less is known about the role of gastrointestinal (GI) tract in the therapeutic mechanisms of exercise in MDD. In addition to the sites of the di...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Liu Y,Xu F,Liu S,Liu G,Yang X,Gao W,Fan K,Zhao H,Ma J

更新日期：2020-12-20 00:00:00

abstract：BACKGROUND:Underconnectivity in the posterior cingulate cortex (PCC) may be associated with a weakened ability to interpret social signals in autism spectrum disorder (ASD) and result in cognitive inflexibility - a hallmark feature of ASD. However, previous neuroimaging studies using resting-state functional magnetic r...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lau WKW,Leung MK,Zhang R

更新日期：2020-12-20 00:00:00

abstract：:Major depressive disorder (MDD) is associated with enhanced anxiety and reduced reward processing leading to impaired cognitive flexibility. These pathological changes during depression are accompanied by dysfunctional hypothalamic-pituitary-adrenal (HPA) axis and its impaired regulation by the amygdala. Notably, the ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Chakraborty S,Tripathi SJ,Raju TR,Shankaranarayana Rao BS

更新日期：2020-12-20 00:00:00

abstract：:Although several recent studies have suggested that neuroinflammation plays a role in depression, both medication and neuroinflammatory preventive strategies have been poorly investigated. Recent studies have indicated that preconditioning with lipopolysaccharide (LPS) reduces the damage that occurs following ischemic...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Koga M,Toda H,Kinoshita M,Asai F,Nagamine M,Shimizu K,Kobayashi Y,Morimoto Y,Yoshino A

更新日期：2020-12-20 00:00:00

abstract：OBJECTIVES:In recent decades, the diagnostic and therapeutic implications of the microbiome changes and the impact of probiotic supplementation have increased rapidly. However, the potential for clinical translation of microbiome research for children and adolescents with psychiatric disorders is unclear. This review e...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ligezka AN,Sonmez AI,Corral-Frias MP,Golebiowski R,Lynch B,Croarkin PE,Romanowicz M

更新日期：2020-12-01 00:00:00

abstract：:While white matter impairments play an integral part in the pathophysiology of schizophrenia and bipolar disorder, the literature on white matter abnormality differences between the two disorders is insufficient. The University of California Los Angeles Consortium for Neuropsychiatric Phenomic LA5c public dataset, inc...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Joo SW,Kim H,Jo YT,Yoon W,Kim Y,Lee J

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:Patients with remitted major depressive disorder (rMDD) generally rely on maladaptive coping strategies for stressful situations. These maladaptive copings are associated with an elevated relapse risk of rMDD; however, their neural basis remains poorly understood. METHODS:We enrolled (1) 45 patients with rM...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Tsujii N,Mikawa W,Adachi T,Sakanaka S,Shirakawa O

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:Cannabis is a neuromodulating substance that acts on central synaptic transmission. Regular cannabis use induces a decreased capacity for dopamine synthesis in the brain. The retina is considered an easy means of investigating dysfunctions of synaptic transmission in the brain. We have previously studied the...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Polli L,Schwan R,Albuisson E,Malbos L,Angioi-Duprez K,Laprevote V,Schwitzer T

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Mood disorders are particularly common, disabling conditions. Diagnosis can be difficult as it may involve different pathophysiological assumptions. This could explain why such disorders are resistant to treatment. The retina is part of the central nervous system and shares a common embryonic origin with the...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Clémence-Fau M,Schwan R,Angioi-Duprez K,Laprévote V,Schwitzer T

更新日期：2020-08-19 00:00:00

abstract：:Individuals may develop fear extinction deficits after life-threatening traumatic events; such deficits indicate posttraumatic stress disorder (PTSD). Because the occurrence of this disorder differs among people who have experienced trauma, hidden underlying factors should be determined. Increasing evidence suggests t...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lin CC,Chen TY,Cheng PY,Liu YP

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Schizophrenia (SCZ) is a highly heritable disorder associated with brain connectivity changes. Although the mechanism of disease expression and vulnerability of SCZ have been reported by previous studies, the mechanism of resilience to SCZ based on the brain structural connectivity is poorly understood. The ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Wei Q,Zhao L,Zou Y,Wang J,Qiu Y,Niu M,Kang Z,Liu X,Tang Y,Li C,Zhang J,Fan X,Huang R,Han Z

更新日期：2020-07-13 00:00:00

abstract：OBJECTIVE:Major depressive disorder (MDD) is a ubiquitous mental illness with heterogeneous symptoms, however, the pathophysiology mechanisms are still not fully understood. Clinical and preclinical studies suggested that depression could cause disturbances in sensory perception systems, disruptions in auditory and vis...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lu F,Cui Q,Huang X,Li L,Duan X,Chen H,Pang Y,He Z,Sheng W,Han S,Chen Y,Yang Y,Luo W,Yu Y,Jia X,Tang Q,Li D,Xie A,Chen H

更新日期：2020-06-08 00:00:00

abstract：:The identification of the cerebral substrates of psychoses such as schizophrenia and bipolar disorder is likely hampered by its biological heterogeneity, which may contribute to the low replication of results in the field. In this study we aimed to replicate in a completely new sample and supplement the results of a p...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Planchuelo-Gómez Á,Lubeiro A,Núñez-Novo P,Gomez-Pilar J,de Luis-García R,Del Valle P,Martín-Santiago Ó,Pérez-Escudero A,Molina V

更新日期：2020-06-08 00:00:00

abstract：:Previous studies have reported abnormalities in static brain activity and connectivity in patients with generalized anxiety disorder (GAD). However, the dynamic patterns of brain connectivity in patients with GAD have not been fully explored. In this study, we aimed to investigate the dynamic local brain functional co...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Cui Q,Chen Y,Tang Q,Han S,Hu S,Pang Y,Lu F,Nan X,Sheng W,Shen Q,Wang Y,He Z,Chen H

更新日期：2020-04-20 00:00:00

abstract：OBJECTIVE:Clinical staging and profiling have been proposed as a new approach in order to refine the diagnostic assessment of schizophrenia spectrum disorders. However, only limited evidence is available for the inter-rater reliability of the clinical staging and profiling model. The aim of the present study was theref...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Berendsen S,van der Paardt JW,Van HL,van Bruggen M,Nusselder H,Jalink M,de Peuter OR,Peen J,van Tricht MJ,de Haan L

更新日期：2020-04-20 00:00:00

abstract：OBJECTIVE:To determine the characteristics of the activation syndrome (AS) that predict the emergence or worsening of suicidal ideation (SI) in the first month of antidepressant treatment with tianeptine, as well as the temporal relationship between both conditions. METHOD:A naturalistic sample of 2422 depressed outpa...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lopez-Castroman J,Jaussent I,Gorwood P,Courtet P

更新日期：2020-03-08 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that is affected by both genetic and environmental factors. Nowadays, OMIC technologies, such as genomics and metabolomics, are providing a systematic readout of genetic structures and physiological states for understanding human diseases. However, th...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Yang L,Lv X,Du H,Wu D,Wang M

更新日期：2020-03-08 00:00:00

abstract：:Adolescence is a developmental period marked by robust neural alterations and heightened vulnerability to stress, a factor that is highly associated with increased risk for emotional processing deficits, such as anxiety. Stress-induced upregulation of the dynorphin/kappa opioid receptor (DYN/KOP) system is thought to,...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Varlinskaya EI,Johnson JM,Przybysz KR,Deak T,Diaz MR

更新日期：2020-03-02 00:00:00

abstract：BACKGROUND:Obsessive-compulsive disorder (OCD) is a clinically heterogeneous condition. To better understand and treat patients, symptomatology of OCD has been categorized into more homogenous symptom dimensions. The autogenous-reactive classification model has proven helpful in the elucidation of the neurobiological s...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Xia J,Fan J,Liu W,Du H,Zhu J,Yi J,Tan C,Zhu X

更新日期：2020-03-02 00:00:00

abstract：:Neuroinflammation and metabolic deficits contribute to the etiology of human affective disorders, such as anxiety and depression. The zebrafish (Danio rerio) has recently emerged as a powerful new model organism in CNS disease modeling. Here, we exposed zebrafish to 2% glucose and 10% cholesterol for 19 days to experi...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Wang J,Li Y,Lai K,Zhong Q,Demin KA,Kalueff AV,Song C

更新日期：2020-01-10 00:00:00

abstract：:The present study aimed to assess the behavioral effects of chronic treatments of different doses of nicotine by using both quantitative and multivariate T-pattern analysis (TPA), which can reveal hidden behavioral structures, in Sprague-Dawley rats tested in the hole-board apparatus. To this purpose, nicotine ditartr...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Casarrubea M,Pierucci M,Aiello S,Cassar D,Deidda G,Crescimanno G,Di Giovanni G

更新日期：2020-01-10 00:00:00

abstract：:Type-5 metabotropic glutamate receptors (mGlu5) have been implicated in the mechanism of resilience to stress. They form part of the postsynaptic density (PSD), a thickening of the glutamatergic synapse that acts as a multimodal hub for multiple cellular signaling. Perinatal stress in rats triggers alterations that ma...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Buonaguro EF,Morley-Fletcher S,Avagliano C,Vellucci L,Iasevoli F,Bouwalerh H,Van Camp G,Nicoletti F,Maccari S,de Bartolomeis A

更新日期：2020-01-10 00:00:00

abstract：BACKGROUND:Posttraumatic stress disorder (PTSD) is a common psychiatric condition that can develop following a traumatic experience. PTSD is associated with significant disability, a large economic burden, and despite the range of therapies to treat PTSD, response to antidepressants is limited. A growing body of clinic...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Bahji A,Forsyth A,Groll D,Hawken ER

更新日期：2020-01-10 00:00:00

abstract：:Sensory symptoms are common in individuals with autism spectrum disorder (ASD). Altered sensory gating may cause sensory overload. However, whether ASD individuals have P50 gating deficits is controversial in childhood and lacks evidence in adulthood. Beyond P50, fewer studies have examined N100 or P200, although N100...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Chien YL,Hsieh MH,Gau SS

更新日期：2019-12-20 00:00:00

abstract：INTRODUCTION:Increased incidence of obesity and excess weight lead to an increased incidence of non-alcoholic fatty liver disease (NAFLD). Recent evidence indicates a protective effect of cannabis consumption on weight gain and related metabolic alterations in psychosis patients. Overall, patients are at greater risk o...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Vázquez-Bourgon J,Ortiz-García de la Foz V,Suarez-Pereira I,Iruzubieta P,Arias-Loste MT,Setién-Suero E,Ayesa-Arriola R,Gómez-Revuelta M,Crespo J,Crespo Facorro B

更新日期：2019-12-20 00:00:00

abstract：:Stem cell is defined by its ability to self-renewal and generates differentiated functional cell types, which are derived from the embryo and various sources of postnatal animal. These cells can be divided according to their potential development into totipotent, unipotent, multipotent andpluripotent. Pluripotent is c...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Amin N,Tan X,Ren Q,Zhu N,Botchway BOA,Hu Z,Fang M

更新日期：2019-12-20 00:00:00

abstract：PURPOSE OF THE REVIEW:Nutrition, as part of lifestyle and modifiable environmental factors, constitutes an interesting approach for the prevention of geriatric syndromes. The objective of this review was to examine the most recent evidence on the association between nutrition, from dietary patterns to specific nutrient...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Feart C

更新日期：2019-12-20 00:00:00

abstract：:Auditory verbal hallucinations (AVHs) constitute a frequent and distressing symptom of schizophrenia, associated with physical, emotional, and cognitive challenges. Despite their clinical importance, changes in the multiple dimensions of AVHs during treatment have rarely been examined, and subjective views thereof hav...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Kim SH,Hwang SS,Jung HY,Kim Y,Ahn YM,Chung IW,Kim YS

更新日期：2019-12-20 00:00:00