abstract：OBJECTIVE:To investigate the role of neutrophil gelatinase-associated lipocalin in the evaluation of renal function, nutrition, anemia and inflammation in patients with chronic kidney diseases. MATERIALS AND METHODS:A total of 302 patients with chronic kidney diseases were selected, and their clinical data, blood neut...

journal_title：Nephrologie & therapeutique

authors： Gu Z,Huang Y,Yang F,Tang S,Sun J,Chen T,Liu F,Wu H,Wang J

更新日期：2021-01-16 00:00:00

abstract：:Focal segmental glomerulosclerosis is a common glomerular histological lesion, which is usually characterised by non-nephrotic range proteinuria or nephrotic syndrome. It may be idiopathic or occurs secondarily to drugs, diabetes, obesity or HIV nephropathy and other infections. Dasatinib, a tyrosine kinase inhibitor ...

journal_title：Nephrologie & therapeutique

authors： Ersoy Yesil E,Sit D,Kayabasi H,Zerenler Gursoy F,Demirbas MB,Ocak Serin S

更新日期：2021-01-08 00:00:00

abstract：:Ischemia-reperfusion injury is an inescapable phenomenon in kidney transplantation. It combines lesional processes of biochemical origin associated with oxydative stress and of immunological origin in connection with the recruitment and activation of innate immunity cells. Histological lesions associate acute tubular ...

journal_title：Nephrologie & therapeutique

authors： Dufour L,Ferhat M,Robin A,Inal S,Favreau F,Goujon JM,Hauet T,Gombert JM,Herbelin A,Thierry A

更新日期：2020-11-01 00:00:00

abstract：:In France, 1 adult out of 3 is affected by hypertension and only 1 hypertensive out of 4 achieves blood pressure targets (<140/90mmHg). This proportion is significantly better in similar countries (e.g. England, Germany, the USA). Nephrologists are particularly concerned since although more than 90 % of Chronic Kidney...

journal_title：Nephrologie & therapeutique

authors： Rubin S,Boulestreau R,Couffinhal T,Combe C,Girerd X

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Self-care education can play an important role in improving the quality of life in hemodialysis patients. PURPOSE:The purpose of this study was to determine the effect of self-care education with teach back method on the quality of life in hemodialysis patients. METHODS:In this pre- and post-test clinical ...

journal_title：Nephrologie & therapeutique

authors： Abbasi Abianeh N,Abdollah Zargar S,Amirkhani A,Adelipouramlash A

更新日期：2020-07-01 00:00:00

abstract：:Access to kidney transplants for patients with end-stage chronic renal disease is a major challenge in France. Registration on the transplant waiting list is a mandatory step to be able to access this technique. The Haute Autorité de santé (HAS) updated, in 2015, the contraindications to access this list. In this cont...

journal_title：Nephrologie & therapeutique

authors： Vabret E,Vigneau C,Bayat S,Frimat L,Monnet É,Hannedouche T,Jacquelinet C

更新日期：2020-05-01 00:00:00

abstract：INTRODUCTION:The FIND-CKD study has validated the use of ferric carboxymaltose (FCM) injection with a target of ferritin level between 400 and 600ng/mL to treat iron deficiency anemia in non-dialysis-dependent chronic kidney disease (ND-CKD) patients. In order to assess this strategy in clinical practice, we constitute...

journal_title：Nephrologie & therapeutique

authors： Romanet T,Bedouch P,Zaoui P

更新日期：2019-04-01 00:00:00

abstract：:IgA vasculitis is a systemic vasculitis affecting small vessels. IgA vasculitis usually affect children whereas it is rare in adults (150 to 200 for 1) in which the disease is often more serious with more frequent and severe nephritis. Prevalence of adult IgA vasculitis is unknown and its annual incidence is 1 in 1 mi...

journal_title：Nephrologie & therapeutique

authors： Pillebout É

更新日期：2019-04-01 00:00:00

abstract：:African-Americans exhibit an excess risk for chronic and end-stage kidney disease compared to the non-African populations. Two APOL1 genetic variants were shown to account for the majority of this racial disparity in glomerulopathies and other non-diabetic kidney disease. The high-risk genotype has only been reported ...

journal_title：Nephrologie & therapeutique

authors： Kaboré NF,Limou S

更新日期：2019-04-01 00:00:00

abstract：:Cytomegalovirus is common in adult recipients (prevalence of 40-90%). Children are typically seronegative but immunosuppression may prone to primary-infection or viral reactivation, with potentially severe consequences. CMV infection incidence in pediatric kidney transplant recipients has seldom been investigated. The...

journal_title：Nephrologie & therapeutique

authors： Tanné C,Roy P,Frobert É,Duncan A,Laurent A,Cochat P

更新日期：2019-03-01 00:00:00

abstract：AIM:Post-streptococcal glomerulonephritis (PSGN) is a frequent cause of acute nephritis in children. This study aimed to describe the epidemiology, clinical characteristics and outcomes of PSGN and look for predictor's factors of severity. METHODS:A 12-year retrospective review of case notes and laboratory data was co...

journal_title：Nephrologie & therapeutique

authors： Maalej B,Ben Amor M,Jallouli M,Weli M,Charfi M,Abdelkefi Y,Chakroun O,Kamoun K,Hachicha J,Rekik N,Gargah T,Gargouri L,Mahfoudh A

更新日期：2018-12-01 00:00:00

abstract：:Post-transplantation lymphoproliferative disorder (PTLD) is a well-know complication after organ transplantation. We report a case of a patient who developed an extramedullary plasmacytoma-like PTLD around his transplanted kidney treated with standard multiple myeloma chemotherapy. Three years after benefiting of a de...

journal_title：Nephrologie & therapeutique

authors： Thibaud V,Rivalan J,Llamas F,Cherel M,Decaux O,Vigneau C

更新日期：2018-12-01 00:00:00

abstract：:High blood pressure during renal disease is highly prevalent and an important risk factor for cardiovascular disease and renal progression. Its optimal management is therefore necessary to improve the prognosis of patients. Several trials concerning the blood pressure target in patients with chronic non-diabetic kidne...

journal_title：Nephrologie & therapeutique

authors： Krummel T,Keller N,Prinz É,Hannedouche T

更新日期：2018-11-01 00:00:00

abstract：:The history of dialysis, which started only half a century ago, is rich in developments and technological innovations. Thanks to scientific progress and the development of knowledge in the field of dialysis, patient survival will continue to increase and quality of life will continue to improve. More precise purificat...

journal_title：Nephrologie & therapeutique

authors： Petitclerc T

更新日期：2018-11-01 00:00:00

abstract：:Buerger's disease or thombo-angiitis obliterans disease is a small vessel's vasculitis, frequently observed in young and smoker's males. Diagnosis is based on both clinical and radiological arguments. There is no specific treatment designed for this disease. We report the case of 43 years old patient presenting with a...

journal_title：Nephrologie & therapeutique

authors： Deffontis T,Kintega R,Jannot M,Nicoud P,Hanf W

更新日期：2018-05-01 00:00:00

abstract：:Studies at the population level must take into account the effect of social insecurity and socioeconomic inequalities on the patient outcomes. Socioeconomic inequalities depend on many determinants that are socially determined. In renal transplantation, these social determinants are not registered in the databases. Th...

journal_title：Nephrologie & therapeutique

authors： Châtelet V,Lobbedez T,Harambat J,Bayat-Makoei S,Glowacki F,Vigneau C

更新日期：2018-04-01 00:00:00

abstract：:Cryoglobulins are immunoglobulins that undergo reversible precipitation at low temperatures. They can induce systemic vasculitis, characterized by purpuric cutaneous lesions, arthritis, peripheral neuropathy, hypocomplementemia and glomerular disease. Renal pathology reveals membranoproliferative glomerulonephritis, w...

journal_title：Nephrologie & therapeutique

authors： Karras A

更新日期：2018-04-01 00:00:00

abstract：:Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and fo...

journal_title：Nephrologie & therapeutique

authors： Buron F,Badet L,Morelon E

更新日期：2018-04-01 00:00:00

abstract：:Salt consumption has substantially increased these last years in our modern societies and far exceeds our needs. It has a great impact on cardiovascular and renal disease and represents a major issue in public health. The present work is a review of observational and interventional studies exploring the relationship b...

journal_title：Nephrologie & therapeutique

authors： Keller N,Krummel T,Hannedouche T

更新日期：2018-04-01 00:00:00

abstract：:The remarkable improvement of the outcome of HIV infection came with the price of substantial toxicity of some antiretrovirals. The first molecules used to treat HIV included an important nephrotoxicity. Zalcitabine, stavudine and didanosine can induce severe lactic acidosis. Lactate production is enhanced and the ren...

journal_title：Nephrologie & therapeutique

authors： Loens C,Amet S,Isnard-Bagnis C,Deray G,Tourret J

更新日期：2018-02-01 00:00:00

abstract：:Due to a national theoretical training provided to all resident for many years and the ongoing discussions to change the organization of the resident training of specialized study diploma (SSD) of nephrology, a survey was done to assess the perception of skills acquired in the management of different clinical situatio...

journal_title：Nephrologie & therapeutique

authors： Moranne O,Peraldi MN,Choukroun G,Brunet P,Rondeau É,Moulin B

更新日期：2017-12-01 00:00:00

abstract：:Mycophenolate mofetil is a prodrug widely used in renal transplantation to prevent organ rejection. It is hydrolyzed to its active compound mycophenolic acid (MPA). MPA area under the curve (AUC0-12h) is considered the best pharmacokinetic parameter for the estimation of MPA exposition and for prediction of rejection....

journal_title：Nephrologie & therapeutique

authors： Gaies E,Ben Sassi M,El Jebari H,Jebabli N,Charfi R,Chokri I,Salouage I,Klouz A,Trabelsi S

更新日期：2017-11-01 00:00:00

abstract：:A 21-year-old man ingested 75g of pure caffeine, in an attempt to commit suicide. This represents 7.5 times the minimal lethal dose. Caffeine, 1,3,7-trimethylxanthine, is the most widely consumed psychoactive compound worldwide. It is mostly found in coffee, tea, energizing drinks and in some drugs. However, it has be...

journal_title：Nephrologie & therapeutique

authors： Colin-Benoit E,Friolet R,Rusca M,Teta D,Gobin N

更新日期：2017-05-01 00:00:00

abstract：:International guidelines suggest lowering elevated phosphorus level to the normal range in patients on dialysis. Among the phosphate-lowering strategies, phosphate binder is frequently used in addition to dietary phosphate restriction and an adequate dialysis strategy. However, serum phosphate concentration higher tha...

journal_title：Nephrologie & therapeutique

authors： Bataille P,Delattre V,Daroux M

更新日期：2017-04-01 00:00:00

abstract：:Hypoxia is a common clinical problem that has profound effects on renal homeostasis. Prolyl-4-hydroxylases PHD1, 2 and 3 function as oxygen sensors and control the activity of hypoxia-inducible factor (HIF), an oxygen-sensitive transcription factor that regulates a multitude of hypoxia responses, which help cells and ...

journal_title：Nephrologie & therapeutique

authors： Haase VH

更新日期：2017-04-01 00:00:00

abstract：:Chronic kidney disease is known to be associated with phosphate retention. The mechanisms are complex and the early increase in serum phosphate levels in chronic kidney disease is not strictly related to the dietary phosphate load or to the degree of phosphate retention. It also implicates the activity of intestinal s...

journal_title：Nephrologie & therapeutique

authors： Ureña Torres PA

更新日期：2017-04-01 00:00:00

abstract：:Plasma exchange is a non-selective apheresis technique that can be performed by filtration or centrifugation allowing rapid purification of high molecular weight pathogens. An immunosuppressive treatment is generally associated to reduce the rebound effect of the purified substance. Substitution solutes such as human ...

journal_title：Nephrologie & therapeutique

authors： Ridel C,Kissling S,Mesnard L,Hertig A,Rondeau É

更新日期：2017-02-01 00:00:00

abstract：:The treatment of end-stage renal disease requires a significant number of drug treatments. At patient level, daily management is somewhat difficult: Number of prescribed pills, medication side effects, treatment of asymptomatic diseases… The objective of the study was to investigate the effect of guidance tailored to ...

journal_title：Nephrologie & therapeutique

authors： Parmier M,Gourieux B,Krummel T,Bazin-Kara D,Dory A,Hannedouche T

更新日期：2016-12-01 00:00:00

abstract：:Protein energy wasting is a major complication in peritoneal dialysis. It is leading to a poor quality of life and increasing mortality. Diagnosis must be early, according to criteria defined by the International society of renal nutrition and metabolism. It is necessary to appropriate the diagnostic tools with dialys...

journal_title：Nephrologie & therapeutique

authors： Castrale C,Azar R,Piquet MA,Lobbedez T

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The end-stage renal disease (ESRD) in children has special features in terms of etiologies, therapeutic modalities and access to renal transplantation. In Tunisia, there are no data on the epidemiology of ESRD in children. The aim of our study was to describe epidemiology of ESRD among Tunisian children. ME...

journal_title：Nephrologie & therapeutique

authors： Jellouli M,Boussetta A,Abidi K,Maalej B,Naija O,Hammi Y,Zarrouk C,Mahfoudh A,Gargah T

更新日期：2016-06-01 00:00:00

abstract：:BK virus is near ubiquitous, with a seroprevalence of around 80% in the general population. Subsequent to an asymptomatic primary infection, BK virus then remains dormant in healthy subjects. Reactivation occurs in immunocompromised people. BKv is pathogenic mainly among patients who have received a kidney transplant,...

journal_title：Nephrologie & therapeutique

authors： Lanot A,Bouvier N,Chatelet V,Dina J,Béchade C,Ficheux M,Henri P,Lobbedez T,Hurault de Ligny B

更新日期：2016-04-01 00:00:00

abstract：:While the CKD-EPI (for Chronic Kidney Disease Epidemiology) equation is now implemented worldwide, utilization of the Cockcroft formula is still advocated by some physicians for drug dosage adjustment. Justifications for this recommendation are that the Cockcroft formula was preferentially used to determine dose adjus...

journal_title：Nephrologie & therapeutique

authors： Delanaye P,Flamant M,Cavalier É,Guerber F,Vallotton T,Moranne O,Pottel H,Boffa JJ,Mariat C

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Online hemodiafiltration (oHDF) is increasingly used in children; we treated 28 children since 2009, adapting this technique to pediatric patients. METHODS:In this service evaluation audit, we assessed plasma electrolytes to evaluate the evolution of total (tCa) and ionized (iCa) during a session, as well a...

journal_title：Nephrologie & therapeutique

authors： Bacchetta J,Sellier-Leclerc AL,Bertholet-Thomas A,Carlier MC,Cartier R,Cochat P,Ranchin B

更新日期：2015-11-01 00:00:00

abstract：:Cytomegalovirus infection in kidney transplantation is associated with increased morbidity and mortality through direct and indirect effects. International guidelines had been recently updated, focusing on diagnostic, prevention strategies and curative treatment. Cytomegalovirus-specific immune response plays also an ...

journal_title：Nephrologie & therapeutique

authors： Kaminski H,Couzi L,Déchanet-Merville J,Merville P

更新日期：2015-11-01 00:00:00

abstract：AIM:To investigate risk factors of renal complications in glycogen storage disease type I, in order to identify practical implications for renal preservation. METHODS:A retrospective study of 38 patients with glycogen storage disease type I. RESULTS:The patients studied were 8.6 years old in average (1.5 to 22 years)...

journal_title：Nephrologie & therapeutique

authors： Ben Chehida A,Bensmaïl T,Ben Rehouma F,Ben Abdelaziz R,Azzouz H,Boudabbous H,Slim Abdelmoula M,Abdelhak S,Kaabachi N,Ben Turkia H,Tebib N

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:Morocco stays far behind other countries in the domain of organ donation and transplantation. Improving the knowledge of Moroccan students, about organ donation and transplantation, can be a key factor in the development of transplant activity. The aim of this study is to evaluate the knowledge, attitudes ...

journal_title：Nephrologie & therapeutique

authors： Esqalli I,Knidiri H,Mahoungou G,Aitlahcen Z,Fadili W,Laouad I

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:Optimal drug treatment may slow down the progression of chronic kidney disease (CKD) and reduce the associated complications. We conducted a study to assess the drug treatment of inpatients with CKD at their discharge. METHODS:We retrospectively collected patient data from the electronic medical record of...

journal_title：Nephrologie & therapeutique

authors： Reutemann B,Beney J,Jordan-von Gunten V,Roulet L

更新日期：2015-02-01 00:00:00

abstract：:When seen, some habits of calcium oxalate monohydrate crystals (whewellite) are so typical of ethylene glycol intoxication that they may be helpful for its diagnosis when circumstances are not clearly established. ...

journal_title：Nephrologie & therapeutique

authors： Montagnac R,Thouvenin M,Luxey G,Schendel A,Parent X

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:In dialysis patients, a misevaluation of dry weight may lead to an increased morbidity and mortality. The aim of this cross-sectional multicenter study was to evaluate the association between residual urinary sodium excretion and extracellular volume status in chronically treated hemodialysis patients. PATI...

journal_title：Nephrologie & therapeutique

authors： Crochette R,Lobbedez T,Hanoy M,Le Roy F,Potier J,Besselièvre T,Cardineau É,Landru I,Ficheux M,Ryckelynck JP,Henri P

更新日期：2014-04-01 00:00:00

abstract：:Perioperative period is very likely to lead to acute renal failure because of anesthesia (general or perimedullary) and/or surgery which can cause acute kidney injury. Characterization of acute renal failure is based on serum creatinine level which is imprecise during and following surgery. Studies are based on variou...

journal_title：Nephrologie & therapeutique

authors： Chhor V,Journois D

更新日期：2014-04-01 00:00:00