Abstract:
INTRODUCTION:Optimal drug treatment may slow down the progression of chronic kidney disease (CKD) and reduce the associated complications. We conducted a study to assess the drug treatment of inpatients with CKD at their discharge. METHODS:We retrospectively collected patient data from the electronic medical record of a Swiss regional hospital for two non-consecutive months. Patients were eligible if their glomerular filtration rate at discharge ranged between 15 and 60 mL/min/1.73 m2. Primary outcome was optimal CKD management, defined by drug treatment conforming to the following 3 criteria: (i) appropriate medication dosage relative to kidney function, (ii) absence of contraindicated medication, and (iii) treatment of any comorbidity/complication related to CKD; or alternatively by the recommendation of a kidney-specific follow-up. RESULTS:The primary outcome was achieved by 45.1% of the 71 patients included. A total of 29.6% had at least one inappropriate medication dosage at discharge, 9.9% left with a drug contraindicated in case of CKD, and 73.2% presented at least one untreated comorbidity/complication at discharge. The most common untreated comorbidity was anaemia. A proposition for a specific follow-up was lacking in 39 of the 56 patients discharged with a non-optimal treatment. CONCLUSION:Drug treatment of patients with CKD may be improved in our setting, especially the treatment of comorbidities/complications related to CKD and the specific ambulatory follow-up.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Reutemann B,Beney J,Jordan-von Gunten V,Roulet Ldoi
10.1016/j.nephro.2014.08.004subject
Has Abstractpub_date
2015-02-01 00:00:00pages
34-41issue
1eissn
1769-7255issn
1872-9177pii
S1769-7255(14)00633-6journal_volume
11pub_type
杂志文章abstract::Hepatitis E virus (HEV) causes epidemics of acute hepatitis in developing countries, and also appears to be an emerging agent in industrialized countries. HEV infection is transmitted via the fecal-oral route, and may be a zoonosis in industrialized countries. HEV infection was thought to be responsible for acute hepa...
journal_title:Nephrologie & therapeutique
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doi:10.1016/j.nephro.2009.10.005
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abstract::Buerger's disease or thombo-angiitis obliterans disease is a small vessel's vasculitis, frequently observed in young and smoker's males. Diagnosis is based on both clinical and radiological arguments. There is no specific treatment designed for this disease. We report the case of 43 years old patient presenting with a...
journal_title:Nephrologie & therapeutique
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
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abstract::Low salt diet for dialysis patients was recommended at the very beginning of dialysis treatment. It was issued from Kempner and Guyton studies who have established the relationship between salt, hypertension, and the role of the kidney in sodium balance. This recommendation vanished from dialysis literature during the...
journal_title:Nephrologie & therapeutique
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
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journal_title:Nephrologie & therapeutique
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journal_title:Nephrologie & therapeutique
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doi:10.1016/j.nephro.2017.01.026
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journal_title:Nephrologie & therapeutique
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journal_title:Nephrologie & therapeutique
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doi:10.1016/j.nephro.2013.11.007
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journal_title:Nephrologie & therapeutique
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journal_title:Nephrologie & therapeutique
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abstract::Ischemia-reperfusion injury is an inescapable phenomenon in kidney transplantation. It combines lesional processes of biochemical origin associated with oxydative stress and of immunological origin in connection with the recruitment and activation of innate immunity cells. Histological lesions associate acute tubular ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.05.001
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2008.08.015
更新日期:2009-04-01 00:00:00
abstract::We report on two cases of hypokaliemic periodic paralysis due to a potassium shift from the extracellular to the intracellular compartment of skeletal muscle cells. The first case occurred in a 15-year-old boy who experienced rapid onset flaccid tetraplegia without neurological abnormalities. Physical exam revealed fa...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.07.012
更新日期:2006-11-01 00:00:00
abstract::Surgical removal of a hemodialysis access after thrombosis is generally not performed as it remains clinically well tolerated. However, it may be the source of distal embolization. We report the case of a 43-year-old patient, kidney recipient, who presented with digital ischemia of the right hand. He had a forearm art...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.12.002
更新日期:2010-04-01 00:00:00
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
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更新日期:2006-09-01 00:00:00
abstract:INTRODUCTION:The treatment of secondary hyperparathyroidism (SHPT) in dialysis patients has changed with the introduction of cinacalcet (CC), which represents a medical alternative to surgical parathyroidectomy (PTX). The aim of our study is to prospectively assess the tolerance and efficacy of CC in patients, treated ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.12.004
更新日期:2010-04-01 00:00:00
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2008.03.009
更新日期:2008-12-01 00:00:00
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.04.003
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.01.008
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2013.09.004
更新日期:2014-02-01 00:00:00
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2013.03.012
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abstract::Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2011.11.005
更新日期:2011-12-01 00:00:00
abstract::Nephrologists should be aware the fact that the angioedema is a common side effect not only under angiotensin-converting enzyme (ACE) inhibitors treatment but also under sartans therapy. The frequency of angioedema under ACE inhibitors is estimated at 1 to 7 per thousand. The physiopathology of ACE angioedema implicat...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2007.03.003
更新日期:2007-06-01 00:00:00
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2015.07.472
更新日期:2016-02-01 00:00:00
abstract::The primitive peritonitis (PP) is one of the rare but severe complications of the nephrotic syndrome. Through a series of 25 children who suffer from a primitive peritonitis complicating or revealing a nephritic syndrome, we tried to analyse the epidemiological and bacteriological aspects of these peritonitis. The mea...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2005.01.010
更新日期:2005-11-01 00:00:00
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journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.07.404
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Emphysematous pyelonephritis is a rare and severe form of acute pyelonephritis. It is defined as the presence of gas-producing bacteria in the kidney and in peri-nepheretic areas. We report a case of emphysematous pyelonephritis on a single kidney associated with urolithiasis. OBSERVATION:A 44-year-old wo...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2008.04.005
更新日期:2009-02-01 00:00:00
abstract::Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and fo...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.02.006
更新日期:2018-04-01 00:00:00
abstract::Recently, several meta-analysis suggested an increased risk of cancers linked to the use of antagonists of angiotensin-2 receptors or inhibitors of angiotensinogen converting enzyme. The results of epidemiological studies are conflicting. Meta-analysis as well as retrospective studies are not reliable and biased, sinc...
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