Abstract:
:Cytomegalovirus infection in kidney transplantation is associated with increased morbidity and mortality through direct and indirect effects. International guidelines had been recently updated, focusing on diagnostic, prevention strategies and curative treatment. Cytomegalovirus-specific immune response plays also an important function in controlling the virus. Here, we propose to present the different components of this specific immune response and the advantages of immune monitoring for patient's management: identification of patients who require a treatment, adaptation of curative treatment length, guidance for resistance genotypic testing.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Kaminski H,Couzi L,Déchanet-Merville J,Merville Pdoi
10.1016/j.nephro.2015.03.005subject
Has Abstractpub_date
2015-11-01 00:00:00pages
465-73issue
6eissn
1769-7255issn
1872-9177pii
S1769-7255(15)00105-4journal_volume
11pub_type
杂志文章,评审abstract::The management of lupus nephritis remains a clinical problem in children as in adults. Corticosteroids, cyclophosphamide and azathioprine have been used with satisfactory response, but the most important problems are their potential toxicities. Therefore, we evaluate the use of mycophenolate mofetil (MMF) as a new age...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2010.07.001
更新日期:2010-12-01 00:00:00
abstract:INTRODUCTION:The FIND-CKD study has validated the use of ferric carboxymaltose (FCM) injection with a target of ferritin level between 400 and 600ng/mL to treat iron deficiency anemia in non-dialysis-dependent chronic kidney disease (ND-CKD) patients. In order to assess this strategy in clinical practice, we constitute...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.10.006
更新日期:2019-04-01 00:00:00
abstract::These guidelines were constructed by the commission of dialysis of the Society of nephrology regarding the venous network and arteries preservation, at the intention of every specialist concerned by vascular access problems. ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.03.006
更新日期:2006-07-01 00:00:00
abstract::IgA vasculitis is a systemic vasculitis affecting small vessels. IgA vasculitis usually affect children whereas it is rare in adults (150 to 200 for 1) in which the disease is often more serious with more frequent and severe nephritis. Prevalence of adult IgA vasculitis is unknown and its annual incidence is 1 in 1 mi...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2019.02.001
更新日期:2019-04-01 00:00:00
abstract::IgA nephropathy is the primitive glomerulonephritis the most frequently encountered worldwide. In about one case out of three, it is responsible for the progression from progressive renal failure to end-stage renal failure. The pathophysiological mechanisms of this disease which is mediated by immune complexes remain ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2010.03.007
更新日期:2010-11-01 00:00:00
abstract::This chapter provides indicators to describe the specificity of End Stage Renal Disease in children in France and to study these patients'outcome and the choices of treatment modalities. In 2011, the incidence and the prevalence of ESRD among patients under 20 years old remained stable at 8 and 53 pmp respectively. Th...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/S1769-7255(13)70044-0
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To investigate the role of neutrophil gelatinase-associated lipocalin in the evaluation of renal function, nutrition, anemia and inflammation in patients with chronic kidney diseases. MATERIALS AND METHODS:A total of 302 patients with chronic kidney diseases were selected, and their clinical data, blood neut...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.10.006
更新日期:2021-01-16 00:00:00
abstract::The overall risk of cancer in the kidney transplant patient is three to five times higher than the risk in the general population, and the risk of cutaneous epitheliomas, the most frequent, is multiplied by 100. There are many causes of posttransplantation cancer involving modifications in the immunosurveillance of ne...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/S1769-7255(08)74238-X
更新日期:2008-10-01 00:00:00
abstract::Malignancies and opportunistic infections are frequently observed after solid-organ transplantation. Their occurrence strongly affects recipient survival. We report the case of a 29-year-old Tunisian kidney-recipient who was diagnosed simultaneously with post-transplant lymphoproliferative disease (PTLD) and visceral ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2011.01.010
更新日期:2011-11-01 00:00:00
abstract::Salt consumption has substantially increased these last years in our modern societies and far exceeds our needs. It has a great impact on cardiovascular and renal disease and represents a major issue in public health. The present work is a review of observational and interventional studies exploring the relationship b...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2018.02.002
更新日期:2018-04-01 00:00:00
abstract::The dramatic occurrence, during haemodialysis sessions, of hemodynamic and cerebral symptoms in a 53-year-old haemodialysed woman with a history of aortocoronary bypass leads to discovery and treatment by percutaneous angioplasty and stenting of a significant stenosis of proximal subclavian artery, ipsilateral to the ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.06.002
更新日期:2009-12-01 00:00:00
abstract::The treatment of end-stage renal disease requires a significant number of drug treatments. At patient level, daily management is somewhat difficult: Number of prescribed pills, medication side effects, treatment of asymptomatic diseases… The objective of the study was to investigate the effect of guidance tailored to ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2016.04.001
更新日期:2016-12-01 00:00:00
abstract::Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2011.11.005
更新日期:2011-12-01 00:00:00
abstract::Due to a national theoretical training provided to all resident for many years and the ongoing discussions to change the organization of the resident training of specialized study diploma (SSD) of nephrology, a survey was done to assess the perception of skills acquired in the management of different clinical situatio...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2017.01.026
更新日期:2017-12-01 00:00:00
abstract::We report on two cases of hypokaliemic periodic paralysis due to a potassium shift from the extracellular to the intracellular compartment of skeletal muscle cells. The first case occurred in a 15-year-old boy who experienced rapid onset flaccid tetraplegia without neurological abnormalities. Physical exam revealed fa...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.07.012
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:The treatment of secondary hyperparathyroidism (SHPT) in dialysis patients has changed with the introduction of cinacalcet (CC), which represents a medical alternative to surgical parathyroidectomy (PTX). The aim of our study is to prospectively assess the tolerance and efficacy of CC in patients, treated ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.12.004
更新日期:2010-04-01 00:00:00
abstract::In France, the incidence of dialysis patients is increasing in people over 75 years and represents 40% of incident patients. In these elderly patients with many comorbidities, the benefit of dialysis in terms of survival and quality of life remains controversial. Using data from REIN, determinants of early mortality w...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/j.nephro.2012.03.008
更新日期:2012-12-01 00:00:00
abstract::The understanding of water traffic through biological membranes has tremendously progressed with the discovery of the aquaporins. Aquaporins water channels inserted in lipid bilayer drive specific, regulated, water flux under osmotic gradient. Some of them, the aquaglycéroporines, are permeated by urea, glycerol and o...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2008.03.009
更新日期:2008-12-01 00:00:00
abstract::In 2009, 8,560 patients with end-stage renal disease living in 20 regions (Alsace, Auvergne, Bourgogne, Bretagne, Centre, Champagne-Ardenne, Corse, Haute-Normandie, Ile de France, la Réunion, Languedoc-Roussillon, Limousin, Lorraine, Midi- Pyrénées, Nord-Pas de Calais, Pays de Loire, Picardie, Poitou- Charentes, Prove...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(11)70009-8
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:Morocco stays far behind other countries in the domain of organ donation and transplantation. Improving the knowledge of Moroccan students, about organ donation and transplantation, can be a key factor in the development of transplant activity. The aim of this study is to evaluate the knowledge, attitudes ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2015.02.003
更新日期:2015-07-01 00:00:00
abstract::Buerger's disease or thombo-angiitis obliterans disease is a small vessel's vasculitis, frequently observed in young and smoker's males. Diagnosis is based on both clinical and radiological arguments. There is no specific treatment designed for this disease. We report the case of 43 years old patient presenting with a...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2017.10.006
更新日期:2018-05-01 00:00:00
abstract::African-Americans exhibit an excess risk for chronic and end-stage kidney disease compared to the non-African populations. Two APOL1 genetic variants were shown to account for the majority of this racial disparity in glomerulopathies and other non-diabetic kidney disease. The high-risk genotype has only been reported ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2019.03.007
更新日期:2019-04-01 00:00:00
abstract::A patient is admitted in hospital to explore a nephrotic proteinuria associated with milky urine. This is explained by a chyluria (presence of lymphatic fluid in the urines), which is due to a pyelolymphatic fistula probably linked to a lymphatic filariasis. Usually, the diagnosis of chyluria can be confirmed by the p...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2009.06.003
更新日期:2009-12-01 00:00:00
abstract:INTRODUCTION:Optimal drug treatment may slow down the progression of chronic kidney disease (CKD) and reduce the associated complications. We conducted a study to assess the drug treatment of inpatients with CKD at their discharge. METHODS:We retrospectively collected patient data from the electronic medical record of...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2014.08.004
更新日期:2015-02-01 00:00:00
abstract::Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and fo...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.02.006
更新日期:2018-04-01 00:00:00
abstract::Ischemia-reperfusion injury is an inescapable phenomenon in kidney transplantation. It combines lesional processes of biochemical origin associated with oxydative stress and of immunological origin in connection with the recruitment and activation of innate immunity cells. Histological lesions associate acute tubular ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.05.001
更新日期:2020-11-01 00:00:00
abstract::When seen, some habits of calcium oxalate monohydrate crystals (whewellite) are so typical of ethylene glycol intoxication that they may be helpful for its diagnosis when circumstances are not clearly established. ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2014.04.003
更新日期:2014-11-01 00:00:00
abstract::Dialysis-related constraints encourage questioning about discontinuation of treatment. In France, the 04/22/2005 law, related to patients' rights and end-of-life issues, defines bounds to treatment withdrawal, authorizing it in specific conditions, to avoid foolish obstinacy. Shortly before the publication of this law...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2007.03.004
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:In dialysis patients, a misevaluation of dry weight may lead to an increased morbidity and mortality. The aim of this cross-sectional multicenter study was to evaluate the association between residual urinary sodium excretion and extracellular volume status in chronically treated hemodialysis patients. PATI...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/j.nephro.2013.11.004
更新日期:2014-04-01 00:00:00
abstract:UNLABELLED:Ethylene glycol is present predominantly in antifreeze,and in industrial solvents. Accidental ingestion of ethylene glycol is relatively rare, but may be potentially lethal. It results in a depression of the central nervous system, a severe metabolic acidosis and an acute renal failure by tubular precipitati...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2008.12.003
更新日期:2009-06-01 00:00:00