Abstract：
:Malignancies and opportunistic infections are frequently observed after solid-organ transplantation. Their occurrence strongly affects recipient survival. We report the case of a 29-year-old Tunisian kidney-recipient who was diagnosed simultaneously with post-transplant lymphoproliferative disease (PTLD) and visceral leishmaniasis (VL). Withdrawal of immunosuppressive therapy together with antiparasitic treatment using liposomal amphotericin B, and anti-CD20 antibodies medication resulted in cure of leishmaniasis and remission from PTLD. This case is of clinical interest because of the uncommon association of VL with PTLD after solid organ transplantation. It is also original by the favourable outcome of VL and PTLD, both known as life-threatening diseases. Also, it illustrates the predisposing role of immunosuppressive therapy in occurrence of opportunistic infections and malignancies after solid organ transplantation.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Bacha MM,Abderrahim E,Ounissi M,Chaouech D,Cherif M,Turki S,Rajhi H,Znaidi N,Bahloul A,Trabelsi S,Khaled S,Ben Abdallah T,Ben Maïz H,Kheder Adoi
10.1016/j.nephro.2011.01.010subject
Has Abstractpub_date
2011-11-01 00:00:00pages
488-93issue
6eissn
1769-7255issn
1872-9177pii
S1769-7255(11)00046-0journal_volume
7pub_type
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
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pub_type： 杂志文章,评审
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pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章,多中心研究
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
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abstract：:Cytomegalovirus infection in kidney transplantation is associated with increased morbidity and mortality through direct and indirect effects. International guidelines had been recently updated, focusing on diagnostic, prevention strategies and curative treatment. Cytomegalovirus-specific immune response plays also an ...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/j.nephro.2015.03.005
更新日期：2015-11-01 00:00:00
abstract：:Access to kidney transplants for patients with end-stage chronic renal disease is a major challenge in France. Registration on the transplant waiting list is a mandatory step to be able to access this technique. The Haute Autorité de santé (HAS) updated, in 2015, the contraindications to access this list. In this cont...
journal_title：Nephrologie & therapeutique
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abstract：:IgA vasculitis is a systemic vasculitis affecting small vessels. IgA vasculitis usually affect children whereas it is rare in adults (150 to 200 for 1) in which the disease is often more serious with more frequent and severe nephritis. Prevalence of adult IgA vasculitis is unknown and its annual incidence is 1 in 1 mi...
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