Abstract：
:The understanding of water traffic through biological membranes has tremendously progressed with the discovery of the aquaporins. Aquaporins water channels inserted in lipid bilayer drive specific, regulated, water flux under osmotic gradient. Some of them, the aquaglycéroporines, are permeated by urea, glycerol and other small solutes in addition to water. More than 450 aquaporins have been described, and 13 in vertebrates. Aquaporins 1-4, 6-8 and 11 are expressed in kidney, all along the nephron except the thick ascending limb of Henle. Each of them has a specific localization and regulation, and contributes to the body water balance.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Pietrement Cdoi
10.1016/j.nephro.2008.03.009subject
Has Abstractpub_date
2008-12-01 00:00:00pages
562-7issue
7eissn
1769-7255issn
1872-9177pii
S1769-7255(08)00102-8journal_volume
4pub_type
杂志文章,评审abstract：:Extracellular content in magnesium represents about 1% of total body content, of which plasma magnesium is thus a poor reflect. Hypomagnesaemia is defined by a value lesser than 0.65mmol/L. Its incidence in hospitalized patients ranges between 10 and 15%. Identification of the physiopathology of hypomagnesaemia relies...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2012.09.002
更新日期：2012-11-01 00:00:00
abstract：:Diabetic nephropathy is a frequent complication in type 2 diabetic. Patients with diabetic nephropathy have a characteristic dyslipidemia profile associated increased concentrations of triglycerides, reduced levels of HDL cholesterol, and qualitative abnormalities of LDL. The dyslipidemia management in patients with d...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：:International guidelines suggest lowering elevated phosphorus level to the normal range in patients on dialysis. Among the phosphate-lowering strategies, phosphate binder is frequently used in addition to dietary phosphate restriction and an adequate dialysis strategy. However, serum phosphate concentration higher tha...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2017.01.004
更新日期：2017-04-01 00:00:00
abstract：UNLABELLED:Ethylene glycol is present predominantly in antifreeze,and in industrial solvents. Accidental ingestion of ethylene glycol is relatively rare, but may be potentially lethal. It results in a depression of the central nervous system, a severe metabolic acidosis and an acute renal failure by tubular precipitati...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2008.12.003
更新日期：2009-06-01 00:00:00
abstract：:Calcium and phosphate play a key role in bone mineralization but have also many other physiological functions. The control of serum phosphate concentration is mandatory to avoid the occurrence of severe metabolic disorders, but is less tightly regulated than serum ionized calcium concentration, which is maintained in ...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2010.12.004
更新日期：2011-04-01 00:00:00
abstract：:BK virus is near ubiquitous, with a seroprevalence of around 80% in the general population. Subsequent to an asymptomatic primary infection, BK virus then remains dormant in healthy subjects. Reactivation occurs in immunocompromised people. BKv is pathogenic mainly among patients who have received a kidney transplant,...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2015.11.003
更新日期：2016-04-01 00:00:00
abstract：:African-Americans exhibit an excess risk for chronic and end-stage kidney disease compared to the non-African populations. Two APOL1 genetic variants were shown to account for the majority of this racial disparity in glomerulopathies and other non-diabetic kidney disease. The high-risk genotype has only been reported ...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2019.03.007
更新日期：2019-04-01 00:00:00
abstract：:Due to a national theoretical training provided to all resident for many years and the ongoing discussions to change the organization of the resident training of specialized study diploma (SSD) of nephrology, a survey was done to assess the perception of skills acquired in the management of different clinical situatio...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2017.01.026
更新日期：2017-12-01 00:00:00
abstract：:Proliferation signal inhibitors (PSI) have been used in France for kidney transplants for some ten years. They provide a certain number of long-term benefits for kidney function in transplant patients due to their anti-proliferation and anti-tumour properties and absence of nephrotoxicity. Their use has been evaluated...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/S1769-7255(09)73430-3
更新日期：2009-12-01 00:00:00
abstract：:Recently, several meta-analysis suggested an increased risk of cancers linked to the use of antagonists of angiotensin-2 receptors or inhibitors of angiotensinogen converting enzyme. The results of epidemiological studies are conflicting. Meta-analysis as well as retrospective studies are not reliable and biased, sinc...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/j.nephro.2012.09.006
更新日期：2013-04-01 00:00:00
abstract：:The recent history of French and Brazilian medicine goes back to the first decades of the xixth century. As regards nephrology, the first links were established starting in the 1950s of the xxth century. Over the past 60 years, the scientific production of the Franco-Brazilian school of nephrology totalized more than ...
journal_title：Nephrologie & therapeutique
pub_type： 历史文章,杂志文章
doi：10.1016/j.nephro.2012.05.004
更新日期：2012-12-01 00:00:00
abstract：:Access to kidney transplants for patients with end-stage chronic renal disease is a major challenge in France. Registration on the transplant waiting list is a mandatory step to be able to access this technique. The Haute Autorité de santé (HAS) updated, in 2015, the contraindications to access this list. In this cont...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2020.02.014
更新日期：2020-05-01 00:00:00
abstract：:We report seven cases of patients treated with fluindione, who presented with acute renal failure, associated with clinical features of allergy: poor status, fever, dyspnea, lymphadenopathy and erythroderma. All patients had elevated eosinophil counts. Renal biopsy disclosed in all cases a tubulo-interstitial nephriti...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2009.01.008
更新日期：2009-07-01 00:00:00
abstract：:IgA vasculitis is a systemic vasculitis affecting small vessels. IgA vasculitis usually affect children whereas it is rare in adults (150 to 200 for 1) in which the disease is often more serious with more frequent and severe nephritis. Prevalence of adult IgA vasculitis is unknown and its annual incidence is 1 in 1 mi...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2019.02.001
更新日期：2019-04-01 00:00:00
abstract：:In 2009, 8,560 patients with end-stage renal disease living in 20 regions (Alsace, Auvergne, Bourgogne, Bretagne, Centre, Champagne-Ardenne, Corse, Haute-Normandie, Ile de France, la Réunion, Languedoc-Roussillon, Limousin, Lorraine, Midi- Pyrénées, Nord-Pas de Calais, Pays de Loire, Picardie, Poitou- Charentes, Prove...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/S1769-7255(11)70009-8
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:The end-stage renal disease (ESRD) in children has special features in terms of etiologies, therapeutic modalities and access to renal transplantation. In Tunisia, there are no data on the epidemiology of ESRD in children. The aim of our study was to describe epidemiology of ESRD among Tunisian children. ME...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,多中心研究
doi：10.1016/j.nephro.2015.09.001
更新日期：2016-06-01 00:00:00
abstract：:Kakimoto and Akazawa, first isolated and identified asymmetric dimethylarginine (ADMA) from human urine in 1970. They speculated that ADMA, and its structural isomer symmetrical dimethylarginine (SDMA), "may be important for the study of various pathological states". It took 22 years before this hypothesis materialize...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/j.nephro.2007.02.002
更新日期：2007-04-01 00:00:00
abstract：:Recombinant human erythropoietin (rHuEPO) has transformed the management chronic renal failure (CKD) and considerably improved the outcome of patients on regular chronic dialysis. However, a significant number of patients fail to respond to high of Erythropoiesis-stimulating agents (ESAs) and several causes of inadequ...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：INTRODUCTION:Emphysematous pyelonephritis is a rare and severe form of acute pyelonephritis. It is defined as the presence of gas-producing bacteria in the kidney and in peri-nepheretic areas. We report a case of emphysematous pyelonephritis on a single kidney associated with urolithiasis. OBSERVATION:A 44-year-old wo...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/j.nephro.2008.04.005
更新日期：2009-02-01 00:00:00
abstract：:Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2011.11.005
更新日期：2011-12-01 00:00:00
abstract：:The renal transplantation is nowadays the reference treatment of ESRD. Living donor kidney transplantation is less often performed in France than in other countries. Nevertheless, numerous French and international surveys have evidenced that it provides the recipients a longer life expectancy and a better quality of l...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,多中心研究
doi：10.1016/S1769-7255(11)70007-4
更新日期：2011-07-01 00:00:00
abstract：:In France, 1 adult out of 3 is affected by hypertension and only 1 hypertensive out of 4 achieves blood pressure targets (<140/90mmHg). This proportion is significantly better in similar countries (e.g. England, Germany, the USA). Nephrologists are particularly concerned since although more than 90 % of Chronic Kidney...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2020.10.001
更新日期：2020-11-01 00:00:00
abstract：:Chronic kidney disease is known to be associated with phosphate retention. The mechanisms are complex and the early increase in serum phosphate levels in chronic kidney disease is not strictly related to the dietary phosphate load or to the degree of phosphate retention. It also implicates the activity of intestinal s...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/j.nephro.2017.01.002
更新日期：2017-04-01 00:00:00
abstract：:Ischemia-reperfusion injury is an inescapable phenomenon in kidney transplantation. It combines lesional processes of biochemical origin associated with oxydative stress and of immunological origin in connection with the recruitment and activation of innate immunity cells. Histological lesions associate acute tubular ...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2020.05.001
更新日期：2020-11-01 00:00:00
abstract：:Since the introduction of the first magnesium pharmaceutical specialty in 1928, multiple medical indications were attributed to magnesium supplementation, despite rigorous scientific researches, leading to a very confuse therapeutic chapter. Real hypomagnesemia, acute or chronic, is rare, however oral magnesium drugs ...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/j.nephro.2013.09.004
更新日期：2014-02-01 00:00:00
abstract：:Overweight, as well as obesity have become mass phenomena with an ever increasing prevalence in most countries all over the world, and are associated with a greater cardiovascular risk and mortality. Weight excess is usually directly related to an additional risk of morbidity and mortality in the general population. I...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
doi：10.1016/S1769-7255(09)75167-3
更新日期：2009-07-01 00:00:00
abstract：:Anti-HLA antibodies formed de novo post-transplantation are involved in the development of acute humoral rejection also known as antibody-mediated rejection. This form of rejection is characterized by histological lesions, a positive C4d-staining of peritubular capillaries and anti-donor antibodies. The presence of an...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/S1769-7255(08)73645-9
更新日期：2008-06-01 00:00:00
abstract：:Buerger's disease or thombo-angiitis obliterans disease is a small vessel's vasculitis, frequently observed in young and smoker's males. Diagnosis is based on both clinical and radiological arguments. There is no specific treatment designed for this disease. We report the case of 43 years old patient presenting with a...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2017.10.006
更新日期：2018-05-01 00:00:00
abstract：:This chapter provides indicators to describe the specificity of End Stage Renal Disease in children in France and to study these patients'outcome and the choices of treatment modalities. In 2011, the incidence and the prevalence of ESRD among patients under 20 years old remained stable at 8 and 53 pmp respectively. Th...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,多中心研究
doi：10.1016/S1769-7255(13)70044-0
更新日期：2013-09-01 00:00:00
abstract：:The financial advantage of the oral treatments of iron is minimised by their low bioavailibility (10 to 20%) and the fact that instructions for oral treatments are often badly followed by the patient (eg: tablets taken too far away from meals inducing frequent digestive problems). In France, since Maltofer (hydroxic f...
journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：
更新日期：2006-11-01 00:00:00
