[Transplantation strategy in type 1 diabetic patients].

Abstract:

:Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and for patients with poor quality of life due to unstable diabetes with life-threatening hypoglycemic events. Both beta cell replacement techniques have different benefits and risks and should be adapted to each type 1 diabetic patient. The transplant strategy must be personalized according to parameters assessed in the pre-transplant period, validated by a multidisciplinary team and reassessed regularly until transplantation.

journal_name

Nephrol Ther

authors

Buron F,Badet L,Morelon E

doi

10.1016/j.nephro.2018.02.006

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

S23-S30

eissn

1769-7255

issn

1872-9177

pii

S1769-7255(18)30021-X

journal_volume

14 Suppl 1

pub_type

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    更新日期:2007-06-01 00:00:00

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  • [Sodium, hypertension, chronic kidney diseases, and public health].

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  • [French-Brazilian school of nephrology].

    abstract::The recent history of French and Brazilian medicine goes back to the first decades of the xixth century. As regards nephrology, the first links were established starting in the 1950s of the xxth century. Over the past 60 years, the scientific production of the Franco-Brazilian school of nephrology totalized more than ...

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  • [Solid tumors after kidney transplantation].

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  • [Kidney transplantation in childhood: from milimeter to centimeters].

    abstract::Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...

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    更新日期:2007-10-01 00:00:00

  • [Post-transplantation anti-HLA antibodies: which relevance?].

    abstract::Anti-HLA antibodies formed de novo post-transplantation are involved in the development of acute humoral rejection also known as antibody-mediated rejection. This form of rejection is characterized by histological lesions, a positive C4d-staining of peritubular capillaries and anti-donor antibodies. The presence of an...

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