[Combination of hemodialysis and hemofiltration in severe caffeine intoxication].


:A 21-year-old man ingested 75g of pure caffeine, in an attempt to commit suicide. This represents 7.5 times the minimal lethal dose. Caffeine, 1,3,7-trimethylxanthine, is the most widely consumed psychoactive compound worldwide. It is mostly found in coffee, tea, energizing drinks and in some drugs. However, it has become really easy to obtain pure caffeine (powder or tablets) on the Internet. Mechanisms of action are dose-dependent. When caffeine overdosing occurs, neurologic, cardiovascular and renal systems are mainly affected. Severe intoxication can be fatal. No antidote is available and treatment is purely symptomatic. Hemoperfusion has previously been carried out in the 1990's to treat patients with caffeine intoxication. Since 2009, hemodialysis and hemofiltration have proposed as well. Our patient was successfully treated with a combination of hemodiafiltration, intermittent and then continuous.


Nephrol Ther


Colin-Benoit E,Friolet R,Rusca M,Teta D,Gobin N




Has Abstract


2017-05-01 00:00:00














  • [A preemptive combined liver-kidney transplantation in Aalpha fibrinogen chain renal amyloidosis].

    abstract::The predominant cause of hereditary renal amyloidosis is a mutation of the fibrinogen Aalpha chain (AFib), the most common being the E526V mutation. The evolution towards terminal renal insufficiency is constant and raises the question of renal transplantation and the risk of recurrence. We describe the case of a Port...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Delabre JP,Pageaux GP,Le Quellec A,Raynaud P,Grateau G,Mourad G

    更新日期:2009-04-01 00:00:00

  • [Sodium, hypertension, chronic kidney diseases, and public health].

    abstract::Salt consumption has substantially increased these last years in our modern societies and far exceeds our needs. It has a great impact on cardiovascular and renal disease and represents a major issue in public health. The present work is a review of observational and interventional studies exploring the relationship b...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Keller N,Krummel T,Hannedouche T

    更新日期:2018-04-01 00:00:00

  • [Acute kidney injury in thromboangiitis obliterans disease].

    abstract::Buerger's disease or thombo-angiitis obliterans disease is a small vessel's vasculitis, frequently observed in young and smoker's males. Diagnosis is based on both clinical and radiological arguments. There is no specific treatment designed for this disease. We report the case of 43 years old patient presenting with a...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Deffontis T,Kintega R,Jannot M,Nicoud P,Hanf W

    更新日期:2018-05-01 00:00:00

  • [Network and epidemiologic information in nephrology: Kidney report 2009].

    abstract::In 2009, 8,560 patients with end-stage renal disease living in 20 regions (Alsace, Auvergne, Bourgogne, Bretagne, Centre, Champagne-Ardenne, Corse, Haute-Normandie, Ile de France, la Réunion, Languedoc-Roussillon, Limousin, Lorraine, Midi- Pyrénées, Nord-Pas de Calais, Pays de Loire, Picardie, Poitou- Charentes, Prove...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章



    更新日期:2011-09-01 00:00:00

  • [Treatments of the martial deficiencies: preparations available in France].

    abstract::The financial advantage of the oral treatments of iron is minimised by their low bioavailibility (10 to 20%) and the fact that instructions for oral treatments are often badly followed by the patient (eg: tablets taken too far away from meals inducing frequent digestive problems). In France, since Maltofer (hydroxic f...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Ranfaing E

    更新日期:2006-11-01 00:00:00

  • [Aortocoronary bypass, haemodialysis and internal mammary artery steal].

    abstract::The dramatic occurrence, during haemodialysis sessions, of hemodynamic and cerebral symptoms in a 53-year-old haemodialysed woman with a history of aortocoronary bypass leads to discovery and treatment by percutaneous angioplasty and stenting of a significant stenosis of proximal subclavian artery, ipsilateral to the ...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Cluzel P,Chabrot P,Citron B,Gazuy N,Cassagnes L,Boyer L,Lipiecki J,Bonniol C

    更新日期:2009-12-01 00:00:00

  • [Impaired hypertension control in France: What the nephrologist needs to know].

    abstract::In France, 1 adult out of 3 is affected by hypertension and only 1 hypertensive out of 4 achieves blood pressure targets (<140/90mmHg). This proportion is significantly better in similar countries (e.g. England, Germany, the USA). Nephrologists are particularly concerned since although more than 90 % of Chronic Kidney...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Rubin S,Boulestreau R,Couffinhal T,Combe C,Girerd X

    更新日期:2020-11-01 00:00:00

  • [Measuring quality of life in end-stage renal disease. Transcultural adaptation and validation of the specific Kidney Disease Quality of Life questionnaire].

    abstract::End-stage renal disease has an important impact on the patients' daily life, which can be measured by quality of life questionnaires. The objective of this work was to adapt the Kidney Disease Quality of Life questionnaire (KDQoL) into French and to determine its basic psychometric properties, i.e. validity and reliab...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Boini S,Leplege A,Loos Ayav C,Français P,Ecosse E,Briançon S

    更新日期:2007-10-01 00:00:00

  • [Renal involvement in glycogen storage disease type 1: Practical issues].

    abstract:AIM:To investigate risk factors of renal complications in glycogen storage disease type I, in order to identify practical implications for renal preservation. METHODS:A retrospective study of 38 patients with glycogen storage disease type I. RESULTS:The patients studied were 8.6 years old in average (1.5 to 22 years)...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Ben Chehida A,Bensmaïl T,Ben Rehouma F,Ben Abdelaziz R,Azzouz H,Boudabbous H,Slim Abdelmoula M,Abdelhak S,Kaabachi N,Ben Turkia H,Tebib N

    更新日期:2015-07-01 00:00:00

  • A case of dasatinib-induced focal segmental glomerulosclerosis in a patient with Philadelphia chromosome positive chronic myeloid leukemia.

    abstract::Focal segmental glomerulosclerosis is a common glomerular histological lesion, which is usually characterised by non-nephrotic range proteinuria or nephrotic syndrome. It may be idiopathic or occurs secondarily to drugs, diabetes, obesity or HIV nephropathy and other infections. Dasatinib, a tyrosine kinase inhibitor ...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Ersoy Yesil E,Sit D,Kayabasi H,Zerenler Gursoy F,Demirbas MB,Ocak Serin S

    更新日期:2021-01-08 00:00:00

  • [Hepatitis E infection in dialysis and after transplantation].

    abstract::Hepatitis E virus (HEV) causes epidemics of acute hepatitis in developing countries, and also appears to be an emerging agent in industrialized countries. HEV infection is transmitted via the fecal-oral route, and may be a zoonosis in industrialized countries. HEV infection was thought to be responsible for acute hepa...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Kamar N,Abravanel F,Mansuy JM,Peron JM,Izopet J,Rostaing L

    更新日期:2010-04-01 00:00:00

  • [Online hemodiafiltration in children and hypoparathyroidism: a single-centre series of cases].

    abstract:BACKGROUND:Due to technical requirements and cost, hemodiafiltration (HDF) is not widely used in pediatrics. We have been using online HDF (oHDF) since 2009 and we observed low parathyroid hormone (PTH) levels despite the accurate management of CKD-MBD. METHODS:We reviewed the medical charts and parameters of mineral ...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Pérouse de Montclos T,Ranchin B,Leclerc AL,Bertholet-Thomas A,Belot A,Cochat P,Bacchetta J

    更新日期:2014-02-01 00:00:00

  • [Kidney transplantation in childhood: from milimeter to centimeters].

    abstract::Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Ranchin B,Demede D,Javouhey E,Basmaison O,Cejka JC,Bertholet-Thomas A,Hameury F,Martin X,Cochat P,Badet L

    更新日期:2011-12-01 00:00:00

  • [Assessment of iron deficiency anemia management in the general hospital of Grenoble: A 12-month follow-up of an intravenous ferric carboxymaltose treatment program in a cohort of patients with non-dialysis-dependent chronic kidney disease].

    abstract:INTRODUCTION:The FIND-CKD study has validated the use of ferric carboxymaltose (FCM) injection with a target of ferritin level between 400 and 600ng/mL to treat iron deficiency anemia in non-dialysis-dependent chronic kidney disease (ND-CKD) patients. In order to assess this strategy in clinical practice, we constitute...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Romanet T,Bedouch P,Zaoui P

    更新日期:2019-04-01 00:00:00

  • [Crystalluria in ethylene glycol intoxication].

    abstract::When seen, some habits of calcium oxalate monohydrate crystals (whewellite) are so typical of ethylene glycol intoxication that they may be helpful for its diagnosis when circumstances are not clearly established. ...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Montagnac R,Thouvenin M,Luxey G,Schendel A,Parent X

    更新日期:2014-11-01 00:00:00

  • [Acetate-free hemodialysis: what does it mean?].

    abstract::Substituting bicarbonate by acetate in dialysis fluids has been proposed for avoiding precipitation of calcium and magnesium carbonates. However, acetate hemodialysis has been abandoned because of deleterious effects of acetate. Conventional bicarbonate hemodialysis is not totally acetate-free, because 3 to 7 mEq/l of...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Petitclerc T,Diab R,Le Roy F,Mercadal L,Hmida J

    更新日期:2011-04-01 00:00:00

  • [Magnesium disorders].

    abstract::Extracellular content in magnesium represents about 1% of total body content, of which plasma magnesium is thus a poor reflect. Hypomagnesaemia is defined by a value lesser than 0.65mmol/L. Its incidence in hospitalized patients ranges between 10 and 15%. Identification of the physiopathology of hypomagnesaemia relies...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Blanchard A,Vargas-Poussou R

    更新日期:2012-11-01 00:00:00

  • [Medical and economic evaluation of new peritoneal dialysis solutions].

    abstract::Conventional peritoneal dialysis solutions are mostly bioincompatible in relationship with a low pH, a high glucose and glucose degradation products (GDP) concentrations inducing anatomical and functional peritoneal membrane alterations. Use of icodextrin solution instead of glucose hypertonic solution preserves perit...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Ryckelynck JP,Lobbedez T,Ficheux M,Chatelet V,Thuillier-Lecouf A,Henri P,Hurault de Ligny B

    更新日期:2009-06-01 00:00:00

  • [Patients on dialysis and the psychological aging process].

    abstract::In reference to psychopathology, the authors highlight several indicators of the aging dialysed patient's psychological functioning. The aim of this work is to extract some indicators in order to help these patients to experience a pleasant aging, in spite of a difficult disease state, constraining care and the presen...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Cupa D,Riazuelo H,Causeret C,Gourdon ML,Pirlot G

    更新日期:2009-04-01 00:00:00

  • [ESRD in children and adolescents].

    abstract::This chapter provides indicators to describe the specificity of End Stage Renal Disease in children in France and to study these patients'outcome and the choices of treatment modalities. In 2011, the incidence and the prevalence of ESRD among patients under 20 years old remained stable at 8 and 53 pmp respectively. Th...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,多中心研究


    authors: Harambat J,Hogan J,Macher MA,Couchoud C,registre du REIN.

    更新日期:2013-09-01 00:00:00

  • [Obesity in haemodialysis: the paradox].

    abstract::Overweight, as well as obesity have become mass phenomena with an ever increasing prevalence in most countries all over the world, and are associated with a greater cardiovascular risk and mortality. Weight excess is usually directly related to an additional risk of morbidity and mortality in the general population. I...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Kunz K,Hannedouche T

    更新日期:2009-07-01 00:00:00

  • [Acute immuno-allergic interstitial nephritis after treatment with fluindione. Seven cases].

    abstract::We report seven cases of patients treated with fluindione, who presented with acute renal failure, associated with clinical features of allergy: poor status, fever, dyspnea, lymphadenopathy and erythroderma. All patients had elevated eosinophil counts. Renal biopsy disclosed in all cases a tubulo-interstitial nephriti...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Reynaud F,Giraud P,Cisterne JM,Verdier D,Kouchakipour Z,Hermelin A,Modesto-Segonds A,Bagheri H,Pourrat J

    更新日期:2009-07-01 00:00:00

  • [Strategies aiming to control hyperphosphatemia in chronic kidney disease].

    abstract::Chronic kidney disease is known to be associated with phosphate retention. The mechanisms are complex and the early increase in serum phosphate levels in chronic kidney disease is not strictly related to the dietary phosphate load or to the degree of phosphate retention. It also implicates the activity of intestinal s...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Ureña Torres PA

    更新日期:2017-04-01 00:00:00

  • [Medical prescriptions in haemodialysis patients: critical analysis].

    abstract:AIM:The aim of the study is to analyse haemodialysis patients' prescriptions accordance with legal registrations in 64 chronic haemodialysis patients during a one-month follow-up period. RESULTS:Patients are taking 9.6+/-3 different drugs. A mean of 2.4+/-1.3 prescriptions per patient disagree with the recommended dru...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,多中心研究


    authors: Riemer E,Werling E,Kribs M,Hamman De Compte A,Dimitrov Y

    更新日期:2005-10-01 00:00:00

  • [Renal involvement of cryoglobulinemia].

    abstract::Cryoglobulins are immunoglobulins that undergo reversible precipitation at low temperatures. They can induce systemic vasculitis, characterized by purpuric cutaneous lesions, arthritis, peripheral neuropathy, hypocomplementemia and glomerular disease. Renal pathology reveals membranoproliferative glomerulonephritis, w...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Karras A

    更新日期:2018-04-01 00:00:00

  • [Haemodialysis and its impact on the quality of life].

    abstract::The haemodialysis has considerably transformed the evolution of chronic renal failure which usually has a precarious evolution. However, this palliative treatment disturbed in several manners the universe of the patient. Our purposes were to evaluate the quality of life of patient on haemodialysis and to identify the ...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,多中心研究


    authors: Nasr M,Hadj Ammar M,Khammouma S,Ben Dhia N,Ghachem A

    更新日期:2008-02-01 00:00:00

  • [Aquaporins in the kidney].

    abstract::The understanding of water traffic through biological membranes has tremendously progressed with the discovery of the aquaporins. Aquaporins water channels inserted in lipid bilayer drive specific, regulated, water flux under osmotic gradient. Some of them, the aquaglycéroporines, are permeated by urea, glycerol and o...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章,评审


    authors: Pietrement C

    更新日期:2008-12-01 00:00:00

  • [Perioperative acute kidney injury and failure].

    abstract::Perioperative period is very likely to lead to acute renal failure because of anesthesia (general or perimedullary) and/or surgery which can cause acute kidney injury. Characterization of acute renal failure is based on serum creatinine level which is imprecise during and following surgery. Studies are based on variou...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Chhor V,Journois D

    更新日期:2014-04-01 00:00:00

  • [Post-transplantation anti-HLA antibodies: which relevance?].

    abstract::Anti-HLA antibodies formed de novo post-transplantation are involved in the development of acute humoral rejection also known as antibody-mediated rejection. This form of rejection is characterized by histological lesions, a positive C4d-staining of peritubular capillaries and anti-donor antibodies. The presence of an...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Glotz D

    更新日期:2008-06-01 00:00:00

  • [The issue of dialysis withdrawal and palliative cares. A 3-year retrospective study carried out at Grenoble university teaching hospital development of a decision-making tool].

    abstract::Dialysis-related constraints encourage questioning about discontinuation of treatment. In France, the 04/22/2005 law, related to patients' rights and end-of-life issues, defines bounds to treatment withdrawal, authorizing it in specific conditions, to avoid foolish obstinacy. Shortly before the publication of this law...

    journal_title:Nephrologie & therapeutique

    pub_type: 杂志文章


    authors: Jarrin G,Maurizi-Balzan J,Laval G

    更新日期:2007-07-01 00:00:00