Abstract：
:A 21-year-old man ingested 75g of pure caffeine, in an attempt to commit suicide. This represents 7.5 times the minimal lethal dose. Caffeine, 1,3,7-trimethylxanthine, is the most widely consumed psychoactive compound worldwide. It is mostly found in coffee, tea, energizing drinks and in some drugs. However, it has become really easy to obtain pure caffeine (powder or tablets) on the Internet. Mechanisms of action are dose-dependent. When caffeine overdosing occurs, neurologic, cardiovascular and renal systems are mainly affected. Severe intoxication can be fatal. No antidote is available and treatment is purely symptomatic. Hemoperfusion has previously been carried out in the 1990's to treat patients with caffeine intoxication. Since 2009, hemodialysis and hemofiltration have proposed as well. Our patient was successfully treated with a combination of hemodiafiltration, intermittent and then continuous.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Colin-Benoit E,Friolet R,Rusca M,Teta D,Gobin Ndoi
10.1016/j.nephro.2016.10.005subject
Has Abstractpub_date
2017-05-01 00:00:00pages
183-187issue
3eissn
1769-7255issn
1872-9177pii
S1769-7255(17)30109-8journal_volume
13pub_type
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
pub_type： 杂志文章,评审
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2011.11.005
更新日期：2011-12-01 00:00:00
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journal_title：Nephrologie & therapeutique
pub_type： 杂志文章
doi：10.1016/j.nephro.2010.10.008
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journal_title：Nephrologie & therapeutique
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doi：10.1016/j.nephro.2012.09.002
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journal_title：Nephrologie & therapeutique
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journal_title：Nephrologie & therapeutique
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