Abstract:
:A 21-year-old man ingested 75g of pure caffeine, in an attempt to commit suicide. This represents 7.5 times the minimal lethal dose. Caffeine, 1,3,7-trimethylxanthine, is the most widely consumed psychoactive compound worldwide. It is mostly found in coffee, tea, energizing drinks and in some drugs. However, it has become really easy to obtain pure caffeine (powder or tablets) on the Internet. Mechanisms of action are dose-dependent. When caffeine overdosing occurs, neurologic, cardiovascular and renal systems are mainly affected. Severe intoxication can be fatal. No antidote is available and treatment is purely symptomatic. Hemoperfusion has previously been carried out in the 1990's to treat patients with caffeine intoxication. Since 2009, hemodialysis and hemofiltration have proposed as well. Our patient was successfully treated with a combination of hemodiafiltration, intermittent and then continuous.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Colin-Benoit E,Friolet R,Rusca M,Teta D,Gobin Ndoi
10.1016/j.nephro.2016.10.005subject
Has Abstractpub_date
2017-05-01 00:00:00pages
183-187issue
3eissn
1769-7255issn
1872-9177pii
S1769-7255(17)30109-8journal_volume
13pub_type
杂志文章abstract:INTRODUCTION:The treatment of secondary hyperparathyroidism (SHPT) in dialysis patients has changed with the introduction of cinacalcet (CC), which represents a medical alternative to surgical parathyroidectomy (PTX). The aim of our study is to prospectively assess the tolerance and efficacy of CC in patients, treated ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.12.004
更新日期:2010-04-01 00:00:00
abstract::Diabetic nephropathy is a frequent complication in type 2 diabetic. Patients with diabetic nephropathy have a characteristic dyslipidemia profile associated increased concentrations of triglycerides, reduced levels of HDL cholesterol, and qualitative abnormalities of LDL. The dyslipidemia management in patients with d...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract::Mitochondrial disorders are genetic defects of oxidative phosphorylation. Oxidative phosphorylation takes place in the mitochondrial inner membrane and consists of the oxidation of fuel molecules by oxygen and the concomitant energy transduction into ATP. The mitochondrial respiratory chain is a complex metabolic path...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2012.10.004
更新日期:2013-04-01 00:00:00
abstract::When seen, some habits of calcium oxalate monohydrate crystals (whewellite) are so typical of ethylene glycol intoxication that they may be helpful for its diagnosis when circumstances are not clearly established. ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2014.04.003
更新日期:2014-11-01 00:00:00
abstract::End-stage renal disease has an important impact on the patients' daily life, which can be measured by quality of life questionnaires. The objective of this work was to adapt the Kidney Disease Quality of Life questionnaire (KDQoL) into French and to determine its basic psychometric properties, i.e. validity and reliab...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2007.05.005
更新日期:2007-10-01 00:00:00
abstract::Definition and classification of acute renal failure evolved in recent years. The acronym "Acute Kidney Injury" replaces "Acute Renal Failure". The RIFLE classification spreads the AKI in three degrees of severity, and two degrees of disease duration. The group Acute Kidney Injury Network refines this classification i...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2010.11.005
更新日期:2011-06-01 00:00:00
abstract::In 2006, 6,509 patients with end-stage renal disease living in 16 regions covering 48(M) inhabitants (79% of the French population), started renal replacement therapy (dialysis or preemptive graft): median age was 71 years; 3% had a preemptive graft. The overall crude annual incidence rate of renal replacement therapy...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract::Beta cell replacement by pancreas or Langerhans islets transplantation is the only way to restore glucose homeostasis in type 1 diabetic patients. The counterpart is the need for long-term immunosuppression. These transplantations are therefore mainly indicated for patients candidates for kidney transplantation and fo...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.02.006
更新日期:2018-04-01 00:00:00
abstract::We report on two cases of hypokaliemic periodic paralysis due to a potassium shift from the extracellular to the intracellular compartment of skeletal muscle cells. The first case occurred in a 15-year-old boy who experienced rapid onset flaccid tetraplegia without neurological abnormalities. Physical exam revealed fa...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.07.012
更新日期:2006-11-01 00:00:00
abstract::We report seven cases of patients treated with fluindione, who presented with acute renal failure, associated with clinical features of allergy: poor status, fever, dyspnea, lymphadenopathy and erythroderma. All patients had elevated eosinophil counts. Renal biopsy disclosed in all cases a tubulo-interstitial nephriti...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.01.008
更新日期:2009-07-01 00:00:00
abstract::The haemodialysis has considerably transformed the evolution of chronic renal failure which usually has a precarious evolution. However, this palliative treatment disturbed in several manners the universe of the patient. Our purposes were to evaluate the quality of life of patient on haemodialysis and to identify the ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/j.nephro.2007.07.008
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:In dialysis patients, a misevaluation of dry weight may lead to an increased morbidity and mortality. The aim of this cross-sectional multicenter study was to evaluate the association between residual urinary sodium excretion and extracellular volume status in chronically treated hemodialysis patients. PATI...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/j.nephro.2013.11.004
更新日期:2014-04-01 00:00:00
abstract::The potential neurotoxicity of betalactam antibiotics are well-known and is frequently associated with drug accumulation in patients with renal failure since these antibiotics are eliminated mostly by kidneys. The regional center of pharmacovigilance of Amiens has collected since 10 years, 20 notifications of neurotox...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2008.10.004
更新日期:2009-04-01 00:00:00
abstract::Overweight, as well as obesity have become mass phenomena with an ever increasing prevalence in most countries all over the world, and are associated with a greater cardiovascular risk and mortality. Weight excess is usually directly related to an additional risk of morbidity and mortality in the general population. I...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/S1769-7255(09)75167-3
更新日期:2009-07-01 00:00:00
abstract::The overall risk of cancer in the kidney transplant patient is three to five times higher than the risk in the general population, and the risk of cutaneous epitheliomas, the most frequent, is multiplied by 100. There are many causes of posttransplantation cancer involving modifications in the immunosurveillance of ne...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/S1769-7255(08)74238-X
更新日期:2008-10-01 00:00:00
abstract::Access to kidney transplants for patients with end-stage chronic renal disease is a major challenge in France. Registration on the transplant waiting list is a mandatory step to be able to access this technique. The Haute Autorité de santé (HAS) updated, in 2015, the contraindications to access this list. In this cont...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.02.014
更新日期:2020-05-01 00:00:00
abstract::Cryoglobulins are immunoglobulins that undergo reversible precipitation at low temperatures. They can induce systemic vasculitis, characterized by purpuric cutaneous lesions, arthritis, peripheral neuropathy, hypocomplementemia and glomerular disease. Renal pathology reveals membranoproliferative glomerulonephritis, w...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.02.003
更新日期:2018-04-01 00:00:00
abstract::The source of living kidney donors in the general population remains underused. The present study aims at assessing the prevalence and the characteristics of potential living kidney donors in Ivory Coast in a view of a project of kidney transplantation in French Black Africa. A survey was undertaken in Abidjan from 30...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.12.003
更新日期:2007-12-01 00:00:00
abstract::In 2009, 8,560 patients with end-stage renal disease living in 20 regions (Alsace, Auvergne, Bourgogne, Bretagne, Centre, Champagne-Ardenne, Corse, Haute-Normandie, Ile de France, la Réunion, Languedoc-Roussillon, Limousin, Lorraine, Midi- Pyrénées, Nord-Pas de Calais, Pays de Loire, Picardie, Poitou- Charentes, Prove...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(11)70009-8
更新日期:2011-09-01 00:00:00
abstract::The dramatic occurrence, during haemodialysis sessions, of hemodynamic and cerebral symptoms in a 53-year-old haemodialysed woman with a history of aortocoronary bypass leads to discovery and treatment by percutaneous angioplasty and stenting of a significant stenosis of proximal subclavian artery, ipsilateral to the ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.06.002
更新日期:2009-12-01 00:00:00
abstract::Graft survival is worse in recipient aged less than 5 years due to the greater risk of vascular thrombosis. Thrombosis may be prevented by the choice of the donor, method of surgery, perioperative hemodynamic optimisation and preventive anti-coagulation. Normal growth is a major objective of the management of transpla...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2011.11.005
更新日期:2011-12-01 00:00:00
abstract::Post-transplantation lymphoproliferative disorder (PTLD) is a well-know complication after organ transplantation. We report a case of a patient who developed an extramedullary plasmacytoma-like PTLD around his transplanted kidney treated with standard multiple myeloma chemotherapy. Three years after benefiting of a de...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.07.404
更新日期:2018-12-01 00:00:00
abstract::IgA nephropathy is the primitive glomerulonephritis the most frequently encountered worldwide. In about one case out of three, it is responsible for the progression from progressive renal failure to end-stage renal failure. The pathophysiological mechanisms of this disease which is mediated by immune complexes remain ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2010.03.007
更新日期:2010-11-01 00:00:00
abstract::Studies at the population level must take into account the effect of social insecurity and socioeconomic inequalities on the patient outcomes. Socioeconomic inequalities depend on many determinants that are socially determined. In renal transplantation, these social determinants are not registered in the databases. Th...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2017.04.003
更新日期:2018-04-01 00:00:00
abstract::While the CKD-EPI (for Chronic Kidney Disease Epidemiology) equation is now implemented worldwide, utilization of the Cockcroft formula is still advocated by some physicians for drug dosage adjustment. Justifications for this recommendation are that the Cockcroft formula was preferentially used to determine dose adjus...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2015.07.472
更新日期:2016-02-01 00:00:00
abstract::The management of lupus nephritis remains a clinical problem in children as in adults. Corticosteroids, cyclophosphamide and azathioprine have been used with satisfactory response, but the most important problems are their potential toxicities. Therefore, we evaluate the use of mycophenolate mofetil (MMF) as a new age...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2010.07.001
更新日期:2010-12-01 00:00:00
abstract::Since the introduction of the first magnesium pharmaceutical specialty in 1928, multiple medical indications were attributed to magnesium supplementation, despite rigorous scientific researches, leading to a very confuse therapeutic chapter. Real hypomagnesemia, acute or chronic, is rare, however oral magnesium drugs ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2013.09.004
更新日期:2014-02-01 00:00:00
abstract::Anti-HLA antibodies formed de novo post-transplantation are involved in the development of acute humoral rejection also known as antibody-mediated rejection. This form of rejection is characterized by histological lesions, a positive C4d-staining of peritubular capillaries and anti-donor antibodies. The presence of an...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(08)73645-9
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Self-care education can play an important role in improving the quality of life in hemodialysis patients. PURPOSE:The purpose of this study was to determine the effect of self-care education with teach back method on the quality of life in hemodialysis patients. METHODS:In this pre- and post-test clinical ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.01.002
更新日期:2020-07-01 00:00:00
abstract::A patient is admitted in hospital to explore a nephrotic proteinuria associated with milky urine. This is explained by a chyluria (presence of lymphatic fluid in the urines), which is due to a pyelolymphatic fistula probably linked to a lymphatic filariasis. Usually, the diagnosis of chyluria can be confirmed by the p...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2009.06.003
更新日期:2009-12-01 00:00:00