Abstract:
:In 2006, 6,509 patients with end-stage renal disease living in 16 regions covering 48(M) inhabitants (79% of the French population), started renal replacement therapy (dialysis or preemptive graft): median age was 71 years; 3% had a preemptive graft. The overall crude annual incidence rate of renal replacement therapy for end-stage renal disease was 137 per million population (pmp) in 16 regions that met exhaustivity, with significant differences in sex and age-adjusted incidence across regions (107 to 179 pmh). At initiation, more than one patient out of two had at least one cardiovascular disease and 37% diabetes (88% Type 2 non-insulin-dependent diabetes). On December 31, 2006, 25,774 patients living in these 16 regions were on dialysis: median age was 69.5 years. On December 31, 19,491 patients were living with a functioning graft: median age was 53 years. The overall crude prevalence rate of dialysis was 536 pmp in 15 regions. The overall crude prevalence rate of renal graft was 409 pmp in 15 regions. The overall crude prevalence rate of renal replacement therapy for end-stage renal disease was 945 pmp in 15 regions, with significant differences in age-adjusted prevalence across regions (765 to 1061 pmh). In the 2002-06 cohort of 18,264 incident patients, the overall one-year survival rate was 82%, 72% at 2 years and 63% at 3 years. Survival decreased with age, but remained above 50% at 2 years in patients older than 75 at RRT initiation. Among the 6,321 new patients starting dialysis in 2006 in the 16 regions, 6% had a BMI lower than 18.5 kg/m(2) and 17% a BMI higher than 30. At initiation, 62% had a haemoglobin value lower than 11g/l and 9% an albumin value lower than 25g/l. The first haemodialysis was started in emergency in 30% of the patients and with a catheter in 48%. On December 31, 2006, 8% treated in the dialysis units of the 16 regions received peritoneal dialysis, of which 38% were treated with automated peritoneal dialysis. 95% of the patients on haemodialysis had 3 sessions per week, with a median duration of 4 hours. In 2006, 2,144 patients received a renal graft. On December 31, 2006, 4,838 patients were on the waiting list for a renal graft in the transplantation centres of the 16 regions.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Couchoud C,Lassalle M,Stengel B,Jacquelinet Csubject
Has Abstractpub_date
2008-07-01 00:00:00pages
S53-167eissn
1769-7255issn
1872-9177pii
S1769-7255(08)73654-Xjournal_volume
4 Suppl 2pub_type
杂志文章abstract::Primary hyperoxalurias are rare recessive inherited inborn errors of glyoxylate metabolism. They are responsible for progressive renal involvement, which further lead to systemic oxalate deposition, which can even occur in infants. Primary hyperoxaluria type 1 is the most common form in Europe and is due to alanine-gl...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2011.03.004
更新日期:2011-07-01 00:00:00
abstract::African-Americans exhibit an excess risk for chronic and end-stage kidney disease compared to the non-African populations. Two APOL1 genetic variants were shown to account for the majority of this racial disparity in glomerulopathies and other non-diabetic kidney disease. The high-risk genotype has only been reported ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2019.03.007
更新日期:2019-04-01 00:00:00
abstract::Psychological support before kidney donation is advocated by all authors, but not systematically proposed by all transplantation centers. An analysis of the literature shows that there are many positive aspects to organ donation including improved self-esteem and quality of life. But many secondary psychological effec...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2007.07.010
更新日期:2008-02-01 00:00:00
abstract::The potential neurotoxicity of betalactam antibiotics are well-known and is frequently associated with drug accumulation in patients with renal failure since these antibiotics are eliminated mostly by kidneys. The regional center of pharmacovigilance of Amiens has collected since 10 years, 20 notifications of neurotox...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2008.10.004
更新日期:2009-04-01 00:00:00
abstract::The history of dialysis, which started only half a century ago, is rich in developments and technological innovations. Thanks to scientific progress and the development of knowledge in the field of dialysis, patient survival will continue to increase and quality of life will continue to improve. More precise purificat...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(18)30644-8
更新日期:2018-11-01 00:00:00
abstract:UNLABELLED:Ethylene glycol is present predominantly in antifreeze,and in industrial solvents. Accidental ingestion of ethylene glycol is relatively rare, but may be potentially lethal. It results in a depression of the central nervous system, a severe metabolic acidosis and an acute renal failure by tubular precipitati...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2008.12.003
更新日期:2009-06-01 00:00:00
abstract::Conventional peritoneal dialysis solutions are mostly bioincompatible in relationship with a low pH, a high glucose and glucose degradation products (GDP) concentrations inducing anatomical and functional peritoneal membrane alterations. Use of icodextrin solution instead of glucose hypertonic solution preserves perit...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(09)74560-2
更新日期:2009-06-01 00:00:00
abstract::IgA vasculitis is a systemic vasculitis affecting small vessels. IgA vasculitis usually affect children whereas it is rare in adults (150 to 200 for 1) in which the disease is often more serious with more frequent and severe nephritis. Prevalence of adult IgA vasculitis is unknown and its annual incidence is 1 in 1 mi...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2019.02.001
更新日期:2019-04-01 00:00:00
abstract::While the CKD-EPI (for Chronic Kidney Disease Epidemiology) equation is now implemented worldwide, utilization of the Cockcroft formula is still advocated by some physicians for drug dosage adjustment. Justifications for this recommendation are that the Cockcroft formula was preferentially used to determine dose adjus...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2015.07.472
更新日期:2016-02-01 00:00:00
abstract::Cryoglobulins are immunoglobulins that undergo reversible precipitation at low temperatures. They can induce systemic vasculitis, characterized by purpuric cutaneous lesions, arthritis, peripheral neuropathy, hypocomplementemia and glomerular disease. Renal pathology reveals membranoproliferative glomerulonephritis, w...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.02.003
更新日期:2018-04-01 00:00:00
abstract::Chronic kidney disease is known to be associated with phosphate retention. The mechanisms are complex and the early increase in serum phosphate levels in chronic kidney disease is not strictly related to the dietary phosphate load or to the degree of phosphate retention. It also implicates the activity of intestinal s...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2017.01.002
更新日期:2017-04-01 00:00:00
abstract::A patient is admitted in hospital to explore a nephrotic proteinuria associated with milky urine. This is explained by a chyluria (presence of lymphatic fluid in the urines), which is due to a pyelolymphatic fistula probably linked to a lymphatic filariasis. Usually, the diagnosis of chyluria can be confirmed by the p...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2009.06.003
更新日期:2009-12-01 00:00:00
abstract::Definition and classification of acute renal failure evolved in recent years. The acronym "Acute Kidney Injury" replaces "Acute Renal Failure". The RIFLE classification spreads the AKI in three degrees of severity, and two degrees of disease duration. The group Acute Kidney Injury Network refines this classification i...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2010.11.005
更新日期:2011-06-01 00:00:00
abstract:INTRODUCTION:Emphysematous pyelonephritis is a rare and severe form of acute pyelonephritis. It is defined as the presence of gas-producing bacteria in the kidney and in peri-nepheretic areas. We report a case of emphysematous pyelonephritis on a single kidney associated with urolithiasis. OBSERVATION:A 44-year-old wo...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2008.04.005
更新日期:2009-02-01 00:00:00
abstract::Perioperative period is very likely to lead to acute renal failure because of anesthesia (general or perimedullary) and/or surgery which can cause acute kidney injury. Characterization of acute renal failure is based on serum creatinine level which is imprecise during and following surgery. Studies are based on variou...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2013.11.007
更新日期:2014-04-01 00:00:00
abstract::Low salt diet for dialysis patients was recommended at the very beginning of dialysis treatment. It was issued from Kempner and Guyton studies who have established the relationship between salt, hypertension, and the role of the kidney in sodium balance. This recommendation vanished from dialysis literature during the...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/s1769-7255(07)80022-8
更新日期:2007-09-01 00:00:00
abstract::The treatment of end-stage renal disease requires a significant number of drug treatments. At patient level, daily management is somewhat difficult: Number of prescribed pills, medication side effects, treatment of asymptomatic diseases… The objective of the study was to investigate the effect of guidance tailored to ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2016.04.001
更新日期:2016-12-01 00:00:00
abstract::For ten years, an increase in the number of elderly patients on renal transplant waiting lists has occured. In an attempt to close the widening gap between supply and demand and because the demand for kidneys for younger patients already surpasses the supply, transplant physicians nowadays accept organs from older don...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2005.12.004
更新日期:2006-02-01 00:00:00
abstract::Protein energy wasting is a major complication in peritoneal dialysis. It is leading to a poor quality of life and increasing mortality. Diagnosis must be early, according to criteria defined by the International society of renal nutrition and metabolism. It is necessary to appropriate the diagnostic tools with dialys...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2016.03.004
更新日期:2016-07-01 00:00:00
abstract::In France, the incidence of dialysis patients is increasing in people over 75 years and represents 40% of incident patients. In these elderly patients with many comorbidities, the benefit of dialysis in terms of survival and quality of life remains controversial. Using data from REIN, determinants of early mortality w...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/j.nephro.2012.03.008
更新日期:2012-12-01 00:00:00
abstract::Cytomegalovirus infection in kidney transplantation is associated with increased morbidity and mortality through direct and indirect effects. International guidelines had been recently updated, focusing on diagnostic, prevention strategies and curative treatment. Cytomegalovirus-specific immune response plays also an ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2015.03.005
更新日期:2015-11-01 00:00:00
abstract::We report seven cases of patients treated with fluindione, who presented with acute renal failure, associated with clinical features of allergy: poor status, fever, dyspnea, lymphadenopathy and erythroderma. All patients had elevated eosinophil counts. Renal biopsy disclosed in all cases a tubulo-interstitial nephriti...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.01.008
更新日期:2009-07-01 00:00:00
abstract::The recent history of French and Brazilian medicine goes back to the first decades of the xixth century. As regards nephrology, the first links were established starting in the 1950s of the xxth century. Over the past 60 years, the scientific production of the Franco-Brazilian school of nephrology totalized more than ...
journal_title:Nephrologie & therapeutique
pub_type: 历史文章,杂志文章
doi:10.1016/j.nephro.2012.05.004
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Self-care education can play an important role in improving the quality of life in hemodialysis patients. PURPOSE:The purpose of this study was to determine the effect of self-care education with teach back method on the quality of life in hemodialysis patients. METHODS:In this pre- and post-test clinical ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.01.002
更新日期:2020-07-01 00:00:00
abstract::Dialysis-related constraints encourage questioning about discontinuation of treatment. In France, the 04/22/2005 law, related to patients' rights and end-of-life issues, defines bounds to treatment withdrawal, authorizing it in specific conditions, to avoid foolish obstinacy. Shortly before the publication of this law...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2007.03.004
更新日期:2007-07-01 00:00:00
abstract::Overweight, as well as obesity have become mass phenomena with an ever increasing prevalence in most countries all over the world, and are associated with a greater cardiovascular risk and mortality. Weight excess is usually directly related to an additional risk of morbidity and mortality in the general population. I...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/S1769-7255(09)75167-3
更新日期:2009-07-01 00:00:00
abstract::The renal transplantation is nowadays the reference treatment of ESRD. Living donor kidney transplantation is less often performed in France than in other countries. Nevertheless, numerous French and international surveys have evidenced that it provides the recipients a longer life expectancy and a better quality of l...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/S1769-7255(11)70007-4
更新日期:2011-07-01 00:00:00
abstract::In 2009, 8,560 patients with end-stage renal disease living in 20 regions (Alsace, Auvergne, Bourgogne, Bretagne, Centre, Champagne-Ardenne, Corse, Haute-Normandie, Ile de France, la Réunion, Languedoc-Roussillon, Limousin, Lorraine, Midi- Pyrénées, Nord-Pas de Calais, Pays de Loire, Picardie, Poitou- Charentes, Prove...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(11)70009-8
更新日期:2011-09-01 00:00:00
abstract::Plasma exchange is a non-selective apheresis technique that can be performed by filtration or centrifugation allowing rapid purification of high molecular weight pathogens. An immunosuppressive treatment is generally associated to reduce the rebound effect of the purified substance. Substitution solutes such as human ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2016.12.002
更新日期:2017-02-01 00:00:00
abstract::The financial advantage of the oral treatments of iron is minimised by their low bioavailibility (10 to 20%) and the fact that instructions for oral treatments are often badly followed by the patient (eg: tablets taken too far away from meals inducing frequent digestive problems). In France, since Maltofer (hydroxic f...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00