Abstract:
:Definition and classification of acute renal failure evolved in recent years. The acronym "Acute Kidney Injury" replaces "Acute Renal Failure". The RIFLE classification spreads the AKI in three degrees of severity, and two degrees of disease duration. The group Acute Kidney Injury Network refines this classification into three stages, to improve the sensitivity in detecting moderate forms. The epidemiology of AKI remains imprecise. In the ICU, more than 30% of patients suffered from AKI, often in a context of multiple organs failure. In addition to serum creatinine and urine output, new biomarkers can be assessed. Their early detection should enable a clearer distinction between "acute tubular necrosis" and other causes of AKI, but also to distinguish patients at risk for pejorative evolution of renal function. The management of AKI based on an optimal resuscitation. The administration of loop diuretics or low dose dopamine showed no benefit. Hydration in prevention of the contrast-induced nephropathy is confirmed. The role of acetylcysteine must be determined. The ideal time to initiate a renal replacement therapy and the choice of the technique remain unresolved. The same goes for the dose of dialysis administered. A systematic application of an algorithm, such as proposed by Bagshow would make comparisons easier and the realisation of multicenter studies will help to clarify these points.
journal_name
Nephrol Therjournal_title
Nephrologie & therapeutiqueauthors
Moonen M,Fraipont V,Radermacher L,Masset C,Firre E,Warling Xdoi
10.1016/j.nephro.2010.11.005subject
Has Abstractpub_date
2011-06-01 00:00:00pages
172-7issue
3eissn
1769-7255issn
1872-9177pii
S1769-7255(10)00250-6journal_volume
7pub_type
杂志文章,评审abstract::The recent history of French and Brazilian medicine goes back to the first decades of the xixth century. As regards nephrology, the first links were established starting in the 1950s of the xxth century. Over the past 60 years, the scientific production of the Franco-Brazilian school of nephrology totalized more than ...
journal_title:Nephrologie & therapeutique
pub_type: 历史文章,杂志文章
doi:10.1016/j.nephro.2012.05.004
更新日期:2012-12-01 00:00:00
abstract::The financial advantage of the oral treatments of iron is minimised by their low bioavailibility (10 to 20%) and the fact that instructions for oral treatments are often badly followed by the patient (eg: tablets taken too far away from meals inducing frequent digestive problems). In France, since Maltofer (hydroxic f...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
abstract::Cytomegalovirus infection in kidney transplantation is associated with increased morbidity and mortality through direct and indirect effects. International guidelines had been recently updated, focusing on diagnostic, prevention strategies and curative treatment. Cytomegalovirus-specific immune response plays also an ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2015.03.005
更新日期:2015-11-01 00:00:00
abstract::The overall risk of cancer in the kidney transplant patient is three to five times higher than the risk in the general population, and the risk of cutaneous epitheliomas, the most frequent, is multiplied by 100. There are many causes of posttransplantation cancer involving modifications in the immunosurveillance of ne...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/S1769-7255(08)74238-X
更新日期:2008-10-01 00:00:00
abstract::Substituting bicarbonate by acetate in dialysis fluids has been proposed for avoiding precipitation of calcium and magnesium carbonates. However, acetate hemodialysis has been abandoned because of deleterious effects of acetate. Conventional bicarbonate hemodialysis is not totally acetate-free, because 3 to 7 mEq/l of...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2010.10.008
更新日期:2011-04-01 00:00:00
abstract:AIM:To investigate risk factors of renal complications in glycogen storage disease type I, in order to identify practical implications for renal preservation. METHODS:A retrospective study of 38 patients with glycogen storage disease type I. RESULTS:The patients studied were 8.6 years old in average (1.5 to 22 years)...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2014.12.007
更新日期:2015-07-01 00:00:00
abstract::Recombinant human erythropoietin (rHuEPO) has transformed the management chronic renal failure (CKD) and considerably improved the outcome of patients on regular chronic dialysis. However, a significant number of patients fail to respond to high of Erythropoiesis-stimulating agents (ESAs) and several causes of inadequ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::Recently, several meta-analysis suggested an increased risk of cancers linked to the use of antagonists of angiotensin-2 receptors or inhibitors of angiotensinogen converting enzyme. The results of epidemiological studies are conflicting. Meta-analysis as well as retrospective studies are not reliable and biased, sinc...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2012.09.006
更新日期:2013-04-01 00:00:00
abstract::The remarkable improvement of the outcome of HIV infection came with the price of substantial toxicity of some antiretrovirals. The first molecules used to treat HIV included an important nephrotoxicity. Zalcitabine, stavudine and didanosine can induce severe lactic acidosis. Lactate production is enhanced and the ren...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2017.12.001
更新日期:2018-02-01 00:00:00
abstract::In France, 1 adult out of 3 is affected by hypertension and only 1 hypertensive out of 4 achieves blood pressure targets (<140/90mmHg). This proportion is significantly better in similar countries (e.g. England, Germany, the USA). Nephrologists are particularly concerned since although more than 90 % of Chronic Kidney...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.10.001
更新日期:2020-11-01 00:00:00
abstract::Since the introduction of the first magnesium pharmaceutical specialty in 1928, multiple medical indications were attributed to magnesium supplementation, despite rigorous scientific researches, leading to a very confuse therapeutic chapter. Real hypomagnesemia, acute or chronic, is rare, however oral magnesium drugs ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2013.09.004
更新日期:2014-02-01 00:00:00
abstract:AIM:The aim of the study is to analyse haemodialysis patients' prescriptions accordance with legal registrations in 64 chronic haemodialysis patients during a one-month follow-up period. RESULTS:Patients are taking 9.6+/-3 different drugs. A mean of 2.4+/-1.3 prescriptions per patient disagree with the recommended dru...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,多中心研究
doi:10.1016/j.nephro.2005.08.002
更新日期:2005-10-01 00:00:00
abstract::The potential neurotoxicity of betalactam antibiotics are well-known and is frequently associated with drug accumulation in patients with renal failure since these antibiotics are eliminated mostly by kidneys. The regional center of pharmacovigilance of Amiens has collected since 10 years, 20 notifications of neurotox...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2008.10.004
更新日期:2009-04-01 00:00:00
abstract::Considering the increasing incidence of diabetic nephropathy and its serious complications, the prevention of nephropathy evolution risk in diabetic patients is the subject of several recently initiated studies. In diabetic patients with advanced nephropathy, the lowering of proteinuria by renin angiotensin system blo...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:
更新日期:2006-05-01 00:00:00
abstract::For ten years, an increase in the number of elderly patients on renal transplant waiting lists has occured. In an attempt to close the widening gap between supply and demand and because the demand for kidneys for younger patients already surpasses the supply, transplant physicians nowadays accept organs from older don...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2005.12.004
更新日期:2006-02-01 00:00:00
abstract::Extracellular content in magnesium represents about 1% of total body content, of which plasma magnesium is thus a poor reflect. Hypomagnesaemia is defined by a value lesser than 0.65mmol/L. Its incidence in hospitalized patients ranges between 10 and 15%. Identification of the physiopathology of hypomagnesaemia relies...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2012.09.002
更新日期:2012-11-01 00:00:00
abstract::Low salt diet for dialysis patients was recommended at the very beginning of dialysis treatment. It was issued from Kempner and Guyton studies who have established the relationship between salt, hypertension, and the role of the kidney in sodium balance. This recommendation vanished from dialysis literature during the...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/s1769-7255(07)80022-8
更新日期:2007-09-01 00:00:00
abstract::We report on two cases of hypokaliemic periodic paralysis due to a potassium shift from the extracellular to the intracellular compartment of skeletal muscle cells. The first case occurred in a 15-year-old boy who experienced rapid onset flaccid tetraplegia without neurological abnormalities. Physical exam revealed fa...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.07.012
更新日期:2006-11-01 00:00:00
abstract::Surgical removal of a hemodialysis access after thrombosis is generally not performed as it remains clinically well tolerated. However, it may be the source of distal embolization. We report the case of a 43-year-old patient, kidney recipient, who presented with digital ischemia of the right hand. He had a forearm art...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2009.12.002
更新日期:2010-04-01 00:00:00
abstract::The source of living kidney donors in the general population remains underused. The present study aims at assessing the prevalence and the characteristics of potential living kidney donors in Ivory Coast in a view of a project of kidney transplantation in French Black Africa. A survey was undertaken in Abidjan from 30...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.12.003
更新日期:2007-12-01 00:00:00
abstract::Clinical nephrology in the european french-speaking countries made great strides just after the 2nd World War. The "Société de Pathologie Rénale" was founded and assembles French, Belgian and Swiss nephrologists. The first studies were physiopathological and bore on acute uremia and the associated hydromineral disorde...
journal_title:Nephrologie & therapeutique
pub_type: 历史文章,杂志文章
doi:10.1016/j.nephro.2009.01.005
更新日期:2009-06-01 00:00:00
abstract::Protein energy wasting is a major complication in peritoneal dialysis. It is leading to a poor quality of life and increasing mortality. Diagnosis must be early, according to criteria defined by the International society of renal nutrition and metabolism. It is necessary to appropriate the diagnostic tools with dialys...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2016.03.004
更新日期:2016-07-01 00:00:00
abstract::BK virus is near ubiquitous, with a seroprevalence of around 80% in the general population. Subsequent to an asymptomatic primary infection, BK virus then remains dormant in healthy subjects. Reactivation occurs in immunocompromised people. BKv is pathogenic mainly among patients who have received a kidney transplant,...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2015.11.003
更新日期:2016-04-01 00:00:00
abstract::Overweight, as well as obesity have become mass phenomena with an ever increasing prevalence in most countries all over the world, and are associated with a greater cardiovascular risk and mortality. Weight excess is usually directly related to an additional risk of morbidity and mortality in the general population. I...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/S1769-7255(09)75167-3
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Self-care education can play an important role in improving the quality of life in hemodialysis patients. PURPOSE:The purpose of this study was to determine the effect of self-care education with teach back method on the quality of life in hemodialysis patients. METHODS:In this pre- and post-test clinical ...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2020.01.002
更新日期:2020-07-01 00:00:00
abstract::Cytomegalovirus is common in adult recipients (prevalence of 40-90%). Children are typically seronegative but immunosuppression may prone to primary-infection or viral reactivation, with potentially severe consequences. CMV infection incidence in pediatric kidney transplant recipients has seldom been investigated. The...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.04.003
更新日期:2019-03-01 00:00:00
abstract::Conventional peritoneal dialysis solutions are mostly bioincompatible in relationship with a low pH, a high glucose and glucose degradation products (GDP) concentrations inducing anatomical and functional peritoneal membrane alterations. Use of icodextrin solution instead of glucose hypertonic solution preserves perit...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/S1769-7255(09)74560-2
更新日期:2009-06-01 00:00:00
abstract::Studies at the population level must take into account the effect of social insecurity and socioeconomic inequalities on the patient outcomes. Socioeconomic inequalities depend on many determinants that are socially determined. In renal transplantation, these social determinants are not registered in the databases. Th...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章,评审
doi:10.1016/j.nephro.2017.04.003
更新日期:2018-04-01 00:00:00
abstract::Cryoglobulins are immunoglobulins that undergo reversible precipitation at low temperatures. They can induce systemic vasculitis, characterized by purpuric cutaneous lesions, arthritis, peripheral neuropathy, hypocomplementemia and glomerular disease. Renal pathology reveals membranoproliferative glomerulonephritis, w...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2018.02.003
更新日期:2018-04-01 00:00:00
abstract::About an observation of aspergillus sinusitis in an hemodialyzed patient, correlation between chronic maxillary sinusitis, its aspergillus origin and previous dental treatments is emphasized. Eventual severe complications then evolved in immunocompromised patients justify having the knowledge of this possible patholog...
journal_title:Nephrologie & therapeutique
pub_type: 杂志文章
doi:10.1016/j.nephro.2006.01.003
更新日期:2006-05-01 00:00:00