听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览ANNALS OF CLINICAL AND LABORATORY SCIENCE期刊下所有文献
  • Thymic Carcinoid as the First Manifestation of Multiple Endocrine Neoplasia Type 1 Syndrome: A Case Report and Review of the Literature.

    abstract::The present study reported a rare case with thymic carcinoid as the first manifestation of multiple endocrine neoplasia type 1 (MEN1) syndrome, which presented with gene mutations of the MEN1 and glucokinase regulatory protein (GCKR). In this report, a 40-year-old male was diagnosed as MEN1 syndrome with thymic carcin...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Zheng M,Chen S,Qi C,Ren L,Zhen Y,Yu X,Wei L

    更新日期:2020-11-01 00:00:00

  • Morphological and Immunohistochemical Features of Placental Damage in Cases of Perinatal Death: Institutional Experience with Emphasis on Viral Etiology.

    abstract:OBJECTIVE:Intrauterine hypoxia/asphyxia is not the cause, but a consequence of different pathological conditions that requires a more detailed study of the morphogenesis of perinatal death. METHODS:Structural changes in placentas of intrauterine fetal demise (IUFD) in different stages of intrauterine period and placen...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Nasyrov RA,Sidorova NA,Melnikova VF,Fedotova EP

    更新日期:2020-11-01 00:00:00

  • The Prognostic Significance of TERT Locus Polymorphism (rs36115365) in Surgically Resected Non-Small Cell Lung Cancer.

    abstract:OBJECTIVE:Telomere length is an important factor for the development of non-small cell lung cancer (NSCLC), and current articles focused on telomere associated genes. We studied the clinicopathological and prognostic implications of rs36115365 polymorphism of the TERT-CLPTM1L locus in NSCLC. The association between rs3...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Lee DH,Jung SJ,Park WJ,Heo YR,Lee JH

    更新日期:2020-09-01 00:00:00

  • MicroRNA-200c Inhibits the Metastasis of Triple-Negative Breast Cancer by Targeting ZEB2, an Epithelial-Mesenchymal Transition Regulator.

    abstract:OBJECTIVE:Triple-negative breast cancer (TNBC) is one of the most common malignant, highly heterogeneous tumors in women. MicroRNAs (miRNAs), such as miR-200c, play an important role in various types of malignant cancer, including TNBC. However, the biological role of miRNA-200c in TNBC is not well understood. In this ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Chen H,Li Z,Zhang L,Zhang L,Zhang Y,Wang Y,Xu M,Zhong Q

    更新日期:2020-07-01 00:00:00

  • Decreased Lymphocyte to Monocyte Ratio and Increased Neutrophil to Lymphocyte Ratio Observed in Rotavirus-Positive Acute Gastroenteritis in Children: A Retrospective Study.

    abstract:OBJECTIVE:To search for hematological parameters changes in human rotavirus (HRV) infectious acute gastroenteritis in children and find useful parameters for the differential diagnosis in low re-source environments. METHODS:In this study, children less than 5 years old were divided into three groups which were rotavir...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Zhang C,Li G,Zhang H,Zhang H,Fei Y

    更新日期:2020-07-01 00:00:00

  • Trust your Endocrinologist - Report and Recommendations on the Ordering of Reverse T3 Testing.

    abstract::Laboratory testing for markers of thyroid function is essential for the diagnosis of thyroid disease, yet, the landscape of thyroid function testing is complex and inappropriate test orders are common. Reverse T3 (rT3) is frequently seen on thyroid function testing menus as a marker of nonthyroidal illness. However, t...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Garnett ER,Pagaduan JV,Devaraj S

    更新日期:2020-05-01 00:00:00

  • Reduction of Drug-Drug Interaction Risk; CDC Guidelines Influence on Opiate Benzodiazepine Prescribing.

    abstract::We examined the results of 1.3 million drug tests performed on patients being monitored for compliance with pain medications and substance abuse rehabilitation to determine if the 2016 CDC prescribing guidelines had any impact on opiate benzodiazepine use. We observed that the combination of the opiate drugs morphine,...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Pesce A,Thomas R,Krock K,Tran K,Ackerman G,Nickley J

    更新日期:2020-05-01 00:00:00

  • Analytical Performance Evaluation of Aptima Herpes Simplex Virus 1 and 2 Assay Using Hologic Panther Instrument.

    abstract:OBJECTIVE:Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are responsible for a variety of human diseases. Therefore, rapid detection of these viruses in clinical laboratory is important. Recently Aptima Herpes Simplex 1 and 2 assay has been approved by the FDA. We evaluated analytical performance of this assay by com...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Dixon RB,Bonaparte J,Greenwood CJ,Davis M,Dasgupta A

    更新日期:2020-03-01 00:00:00

  • Circulating miRNA-199a and miRNA-122 Levels as Potential Diagnostic and Prognostic Biomarkers for Hepatocellular Carcinoma.

    abstract:OBJECTIVE:MicroRNAs (miRNAs) are associated with hepatocellular carcinoma (HCC) progression and metastasis. However, it is unclear whether they could act as biomarkers for HCC diagnosis and prognosis. METHODS:In this study, the miR-122 and miR-199a expression levels were determined by quantitative real-time PCR (qRT-P...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Wu J,Wu Y,Luo Y,Li X,Lin N,Yang X,Lin Y,Chen M

    更新日期:2020-03-01 00:00:00

  • Comparison of Matrix-assisted Laser Desorption Ionization Time-of-flight Mass Spectrometry (MALDI-TOF MS) and the Vitek 2 System for Routine Identification of Clinically Relevant Bacteria and Yeast.

    abstract:OBJECTIVE:In this study, we compared the observed agreement and correlation of the Vitek 2 system with the biomarker-based MALDI-TOF MS identification results of bacteria and yeast on a routine basis. METHODS:Clinical isolates collected from two years were included. Isolates were identified using the Vitek 2 system an...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Garza-González E,Camacho-Ortíz A,Rodríguez-Noriega E,Esparza-Ahumada S,Flores-Treviño S,Bocanegra-Ibarias P,Tijerina-Rodríguez L,Morfín-Otero R

    更新日期:2020-01-01 00:00:00

  • Yeast Extract Induces Apoptosis and Cell Cycle Arrest via Activating p38 Signal Pathway in Colorectal Cancer Cells.

    abstract::The microbiome has recently become a key interest for cancer research. Anti-tumor effects of reinforced clostridium media (RCM) were investigated for all ingredients of RCM, which showed that yeast extract could be a candidate for this phenomenon. MTT assay, cell counting, cell death analysis, cell cycle analysis, and...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Moon D,Kang HK,Kim J,Yoon SP

    更新日期:2020-01-01 00:00:00

  • Changes in Expression of Follicular Glucose Transporters May Be Involved in Ovarian Function Impairment during Diabetic Hyperglycemia.

    abstract::Diabetes-induced hyperglycemia has a direct damaging effect on ovarian function. Despite its deadly impact on ovaries, the mechanism of this condition has not been fully elucidated. Glucose transporters are involved in glucose uptake and utilization. Many transporters have been detected in the ovaries, but their roles...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Xu B,Hu Y,Luo YT,Xu H,Qi SH,Zhang YY,Zhao D,Yuan DZ

    更新日期:2019-11-01 00:00:00

  • BCR/ABL1 Transcripts in Healthy Individuals: A Comparative Analysis Between First-Degree Relatives of Patients with Chronic Myelogenous Leukemia and Subjects without Antecedents of the Disease.

    abstract::BCR/ABL1 transcripts, the molecular hallmarks of chronic myeloid leukemia (CML), have been detected in peripheral blood from healthy individuals. Although CML is a sporadic disease, familial occurrence has been reported. This raises the question of whether there is a hereditary factor related to the etiology of CML. O...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Meza-Espinoza JP,Vásquez-Jiménez EA,Barajas-Torres RL,Magaña-Torres MT,González-García JR

    更新日期:2019-11-01 00:00:00

  • Identification of Yersinia Pestis of Xilingele Plateau Ecotype Isolated from China Using Insertion Sequences as Target.

    abstract:OBJECTIVE:This study aims to develop a strategy for distinguishing Yersinia pestis of the Xilingele Plateau ecotype from other biovar of Yersinia pestis using insertion sequences. METHODS:Genome computational analysis was used to discover the positions of insertion sequences unique to Yersinia pestis 91001. PCR was us...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Zhang Z,Wu L,Liang Y,Wang S,He J,Yu D,Li W

    更新日期:2019-09-01 00:00:00

  • Deletion of miR-15 Protects Against Rheumatoid Arthritis via Deregulating its Target Gene BCL2L2 and Repressing NF-κB Pathway.

    abstract:OBJECTIVE:MiR-15 is involved in modulating many cellular processes that are normally destroyed in disease. The regulation of the cell cycle, angiogenesis, and responses to cellular stress are notable processes influenced by MiR-15. MiR-15 plays a critical role in the model of inflammation-related angiogenesis defects. ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Li G,Qiu Z

    更新日期:2019-09-01 00:00:00

  • Evaluation of the Value of Anti-Citrullinated α-enolase Peptide 1 Antibody in the Diagnosis of Rheumatoid Arthritis.

    abstract:GOALS:Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. The α enolase is a nuclear glycolytic enzyme. Antibodies to citrullinated-enolase peptide1(anti-CEP-1) are found in approximately 40% of patients with RA, but the diagnostic value of anti-CEP-1 for RA is not clear. METHODS:We enrolled 282 patient...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Zhou J,Feng L,Zhang H,Wang T,Cui L

    更新日期:2019-09-01 00:00:00

  • New Insight into the Role of Exosomes in Pancreatic Cancer.

    abstract::Pancreatic cancer is one of the most lethal diseases among solid malignancies. Most patients are diagnosed in the late stage or after metastasis. Notably, pancreatic cancer is resistant to chemotherapy and lacks efficient target therapy methods. Given that, investigating the mechanism of metastasis, finding biomarkers...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,评审

    doi:

    authors: Wang CC,Zhao YM,Wang HY,Zhao YP

    更新日期:2019-05-01 00:00:00

  • The Prognostic Value of Measuring PD-L1 mRNA Expression Levels in Surgically Resected Non-Small Cell Lung Cancer.

    abstract::The expression of programmed cell death 1-ligand 1 (PD-L1) by tumor cells acts as an immune-checkpoint when it interacts with its receptor on immune cells, effectively preventing the immune system from attacking the tumor. Inhibitors against PD-L1 have shown remarkable therapeutic activity in non-small cell lung cance...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Kim GJ,Lee JH,Park WJ,Lee HW,Hwang IS,Lee DH

    更新日期:2019-05-01 00:00:00

  • Serum C1q Concentration Positively Correlates with Erythrocyte Sedimentation Rate in Polymyositis/Dermatomyositis.

    abstract::C1q is an important component of the classical complement pathway. This study aimed to investigate C1q concentrations in the sera of PM/DM patients. C1q concentrations were measured in the sera of 87 PM/DM patients and 100 healthy subjects. In addition, the association between C1q concentration and laboratory indexes ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Li L,Chen J,Chen S,Liu C,Zhang F,Li Y

    更新日期:2019-03-01 00:00:00

  • Clinical and Prognostic Value of Human Mammary Tumor Virus in Korean Patients with Breast Carcinoma.

    abstract:BACKGROUND:Human mammary tumor virus (HMTV) is 90-95% homologous to mouse mammary tumor virus, one of the causal agents of murine mammary tumors. Although HMTV has been frequently detected in human breast cancers, its clinical and prognostic value remains unknown. METHODS:In the present study, we analyzed HMTV infecti...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Seo I,Cho JH,Lee MH,Park WJ,Kwon SY,Lee JH

    更新日期:2019-03-01 00:00:00

  • The Association between Platelet Distribution Width and Stroke in Atrial Fibrillation Patients.

    abstract:AIMS:To explore the association between platelet distribution width (PDW) and stroke in atrial fibrillation (AF) patients. METHODS:This study included 150 AF patients who were divided into stroke and non-stroke groups. Multivariate logistic regression analysis and area under the receiver operating characteristic curve...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Lyu QS,Liu B,Huang C,Huang YQ

    更新日期:2019-01-01 00:00:00

  • Influence of Docosahexaenoic Acid on Proliferation and Apoptosis in Human HepG2 Cell Line.

    abstract:OBJECTIVE:This study aims to investigate the effect of different concentrations of docosahexaenoic acid (DHA) on proliferation and apoptosis in HepG2 cell lines, and to research the possible molecular mechanisms. METHODS:DHA concentration was 0 g/mL in the negative control group, and 15, 30, 45, 60 and 75 ug/mL, respe...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Chen YJ,Jiang HT,Wang TF

    更新日期:2019-01-01 00:00:00

  • A Phenotypically Unusual Hemoglobin H Disease Resulting from a Rare α-Globin Genotype (-SEA/-α27.6).

    abstract::Hemoglobin H (Hb H) disease is usually characterized by the existence of Hb H, which influences the degree of functional anemia. We here report a patient with a rare Hb H disease genotype (-SEA/-α27.6), who was observed to paradoxically have no detectable Hb H fraction on electrophoresis. To date, the reason why the q...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Ling LQ,Chen H,Yu SL,Chen S,Liu CN,Li Q,Wang MJ,Zhou J

    更新日期:2018-11-01 00:00:00

  • Upregulated Expression of Serum Exosomal microRNAs as Diagnostic Biomarkers of Lung Adenocarcinoma.

    abstract::Lung cancer is the leading cause of cancer-related death worldwide. Lung adenocarcinoma (AC) cases account for approximately 40% of lung cancers. Early diagnosis can reduce mortality, improve prognosis, prolong survival, and improve quality of life. Specific and stable biomarkers for early diagnosis of AC are still la...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Feng M,Zhao J,Wang L,Liu J

    更新日期:2018-11-01 00:00:00

  • High Mean Platelet Volume Is Associated with Worse Outcomes in Patients with HBV-Related Decompensated Cirrhosis.

    abstract:BACKGROUND:Mean platelet volume (MPV) is an inexpensive, routinely measured clinical parameter, and its elevation shows an increase in the size and activity of platelets. It has been shown that MPV can be used as a prognostic biomarker in certain chronic diseases. In the present study, MPV in patients with hepatitis B ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Ma Y,Quan W,Zhu H

    更新日期:2018-09-01 00:00:00

  • Identification of Candidate Genes Associated with Chemotherapy Resistance in Ovarian Cancer.

    abstract::Ovarian cancer is the leading cause of death due to malignant tumors in female reproductive organs. However, the lack of understanding regarding its pathogenesis brings difficulties to study it. In this study, we analyze the differently expressed genes in both GSE54388 (ovarian cancer vs. normal ovarian tissues) and G...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Zhang B,Wang L,Zhao X,Wei Y,Zhang Y

    更新日期:2018-09-01 00:00:00

  • CYP3A4*1B Polymorphism and Cancer Risk: A Meta-Analysis Based on 55 Case-control Studies.

    abstract::Published data on the association between CYP3A4*1B polymorphism and cancer risk are inconclusive. To derive a more precise estimation of the association, we conducted a meta-analysis. A systematic search of the PubMed database was performed. A total of 55 separate studies including 22072 cancer cases and 25433 contro...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章,meta分析

    doi:

    authors: Zheng Y,Xu Y,Zhou BY,Sun L,Yu PB,Zhang L,Xu J,Wang JJ

    更新日期:2018-07-01 00:00:00

  • A Pilot Study of RSK4 Expression in Patients with Human Non-Small Cell Lung Carcinoma.

    abstract:BACKGROUND:Lung cancer represents the leading cause of cancer deaths worldwide, with non-small cell lung carcinoma (NSCLC) comprising the most common type of lung cancer. OBJECTIVE:The aim of this pilot study was to ascertain RSK4 expression at both the gene and protein level in normal and cancerous tissue of patients...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Li A,Liu D,Liu Y,Zhou Y,Du Z,Song J

    更新日期:2018-07-01 00:00:00

  • Mechanisms of Resistance in Clinical Isolates of Enterobacter cloacae that Are Less Susceptible to Cefepime than to Ceftazidime.

    abstract::Thirty-two Enterobacter cloacae strains that are less susceptible to cefepime than to ceftazidime were collected. This unique phenotype of 8 strains was confirmed using the agar dilution method. OXA1, OXA10, OXA31 and OXA35 were detected in 3, 2, 3, and 2 strains, respectively, whereas all strains were negative for PS...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Liu L,Yu J,Tang M,Liu J

    更新日期:2018-05-01 00:00:00

  • Major Discrepancies of HCV Viral Loads Determined by Real Time Polymerase Chain Reaction Caused by Use of Collection Tubes that Differ Only with the Presence or Absence of Serum Separator.

    abstract:BACKGROUND:For viral load (VL) analysis of hepatitis C virus (HCV) by Real Time PCR, approved collection tubes were lavender top (LTT) and plasma processing (PPT) tubes, that differ in that PPTs include plasma separator. Using a Real Time PCR method, we investigated how the results correlated for the two tube types. M...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Wang X,Momeni A,Eid I,Li L,Brackett F,Davis-Smith B,Wieczorek R,Pincus MR

    更新日期:2018-05-01 00:00:00

  • Cryopreservation of Genotyped ABO Subgroup RBCs for Quality Assurance of ABO Grouping Reagents.

    abstract:BACKGROUND:Quality assurance of newly developed or manufactured blood grouping reagents with reagent red blood cells (RBCs) is crucial in the process of product approval by governmental agency. However, RBCs with rare blood group are not easily available in the fresh state. We investigated the feasibility of cryopreser...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Kim S,Song S,Kim HO

    更新日期:2018-03-01 00:00:00

  • Micronuclei Induction in Amniotic Fluid Cells from Cyclophosphamide Treated Rats.

    abstract::The aim of the study was to determine if amniotic fluid cells of rats can be used to provide evidence of genotoxicity. In order to do that micronuclei formation was induced in rats during pregnancy after treatment with cyclophosphamide (CP), at different CP doses. On gestational day 19, we collected the amniotic fluid...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Gomez-Mariscal K,Gómez-Meda BC,Zamora-Perez AL,Sánchez-Parada MG,Gallegos-Arreola MP,Zúñiga-González GM

    更新日期:2018-03-01 00:00:00

  • Analytical and Clinical Performance Evaluation of the Abbott Architect PIVKA Assay.

    abstract::Protein induced by vitamin K absence (PIVKA) is measured using various assays and is used to help diagnose hepatocellular carcinoma. The present study evaluated the analytical and clinical performances of the recently released Abbott Architect PIVKA assay. Precision, linearity, and correlation tests were performed in ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Ko DH,Hyun J,Kim HS,Park MJ,Kim JS,Park JY,Shin DH,Cho HC

    更新日期:2018-01-01 00:00:00

  • RASGRF1 Hypermethylation, a Putative Biomarker of Colorectal Cancer.

    abstract:OBJECTIVE:RASGRF1 is a guanine nucleotide exchange factor, which promotes the release of GDP from inactive Ras and stabilizes the apoprotein. In this study, the methylation status of RASGRF1 promoter and its correlation with clinicopathological parameters were evaluated in colorectal cancer (CRC). METHODS:Methylation-...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Chen H,Xu Z,Yang B,Zhou X,Kong H

    更新日期:2018-01-01 00:00:00

  • A Novel Inherited Mutation of SCN8A in a Korean Family with Benign Familial Infantile Epilepsy Using Diagnostic Exome Sequencing.

    abstract::Mutations in SCN8A, which codes for the voltage-gated sodium channel NaV1.6, have been described in relation to infantile onset epilepsy with developmental delay and cognitive impairment. Here, we report the case of an infant and her father with early onset benign familial infantile epilepsy, but without cognitive or ...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Han JY,Jang JH,Lee IG,Shin S,Park J

    更新日期:2017-11-01 00:00:00

  • T Cell Immunoglobulin- and Mucin-Domain-Containing Molecule 3 Gene Polymorphisms and Susceptibility to Invasive Breast Cancer.

    abstract::The T-cell immunoglobulin and mucin domain containing molecule 3 (TIM-3) gene is an important immune regulatory molecule. In fact, studies have shown that polymorphisms in the (TIM-3) gene may be associated with various cancers. The goal of this study was to investigate whether the -1516G/T, -574G/T, or +4259T/G singl...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Cheng S,Ju Y,Han F,Wang Y,Xu Y,Qu T,Lu Z

    更新日期:2017-11-01 00:00:00

  • Novel Germline p.Gly42Val MEN1 Mutation in a Family with Multiple Endocrine Neoplasia Type 1 - Excellent Response of Prolactinoma to Cabergoline.

    abstract::We report on a 27-year-old male patient presenting with renal colic secondary to hyperparathyroidism. Further investigations confirmed a diagnosis of type 1 multiple endocrine neoplasia and revealed a 2.0 cm pancreatic neuroendocrine tumour as well as a pituitary macroadenoma with significantly elevated prolactin leve...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Koehler VF,Jungheim K,Groß U,Iacovazzo D,Mann A,Korbonits M

    更新日期:2017-09-01 00:00:00

  • Detection of the Single Nucleotide Polymorphism at Position rs2735940 in the Human Telomerase Reverse Transcriptase Gene by the Introduction of a New Restriction Enzyme Site for the PCR-RFLP Assay.

    abstract::It has been shown that the single nucleotide polymorphism (SNP) of the rs2735940 site in the human telomerase reverse transcriptase (hTERT) gene is associated with increased cancer risk. The traditional method to detect SNP genotypes is polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). How...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Wang S,Ding M,Duan X,Wang T,Feng X,Wang P,Yao W,Wu Y,Yan Z,Feng F,Yu S,Wang W

    更新日期:2017-09-01 00:00:00

  • Vitamin D and Immunomodulation: Is It Time to Change the Reference Values?

    abstract::The term "vitamin D" refers to two chemical compounds - ergosterol, or vitamin D2, and cholecalciferol, or vitamin D3. Active vitamin D3 is correctly regarded as a neurohormone due to its pleiotropic biological activities. Although the relation between vitamin D and calcium-phosphorus metabolism has never been discuss...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Bivona G,Agnello L,Ciaccio M

    更新日期:2017-08-01 00:00:00

  • Impact of TLR 2, TLR 4-activation on the Expression of ABCA1 and ABCG1 in Raw Cells.

    abstract::Toll-like receptors (TLR) activation is thought to modulate the macrophage cholesterol efflux and contribute to the atherosclerosis progression; however, the precise pathophysiological mechanism remains unclear. We investigated the effects of TLR2- and TLR4-activation on the expression of the ATP-binding cassette (ABC...

    journal_title:Annals of clinical and laboratory science

    pub_type: 杂志文章

    doi:

    authors: Suzuki K,Kawakami Y,Yamauchi K

    更新日期:2017-08-01 00:00:00

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