Abstract:
:Ovarian cancer is the leading cause of death due to malignant tumors in female reproductive organs. However, the lack of understanding regarding its pathogenesis brings difficulties to study it. In this study, we analyze the differently expressed genes in both GSE54388 (ovarian cancer vs. normal ovarian tissues) and GSE51373 (chemotherapy-resistant vs. chemotherapy-sensitive tissues). By intersecting the differently expressed genes, 79 genes were identified. Then, further function enrichment analysis, including GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis, was performed. Also, a protein-protein network analysis was conducted to reveal the potential relationship between genes. Finally, survival analysis was utilized to find out that FOXL2 (Forkhead Box L2), TIMP3 (TIMP Metallopeptidase Inhibitor 3), and ZEB1 (Zinc Finger E-Box Binding Homeobox 1) may serve as biomarkers for predicting the prognosis of ovarian cancer patients.
journal_name
Ann Clin Lab Scijournal_title
Annals of clinical and laboratory scienceauthors
Zhang B,Wang L,Zhao X,Wei Y,Zhang Ysubject
Has Abstractpub_date
2018-09-01 00:00:00pages
573-579issue
5eissn
0091-7370issn
1550-8080pii
48/5/573journal_volume
48pub_type
杂志文章abstract::In the past, necrotizing vasculitis has been considered to be one of the dominant intrarenal vascular abnormalities in systemic lupus erythematosus (SLE). To test the validity of this statement, 70 consecutive renal biopsies from patients with SLE were reviewed. Light microscopy (LM) and immunofluorescence (IF) studie...
journal_title:Annals of clinical and laboratory science
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
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journal_title:Annals of clinical and laboratory science
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journal_title:Annals of clinical and laboratory science
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journal_title:Annals of clinical and laboratory science
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2011-04-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2015-07-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2017-11-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:2006-04-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1982-03-01 00:00:00
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journal_title:Annals of clinical and laboratory science
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doi:
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
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journal_title:Annals of clinical and laboratory science
pub_type: 杂志文章,评审
doi:
更新日期:1999-04-01 00:00:00
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journal_title:Annals of clinical and laboratory science
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doi:
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