解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:The shift toward a preventative approach in medical aftercare of congenital heart disease (CHD) patients has led to encouragement of regular physical activity (PA) in this patient population. Objective measures are crucial in accurately displaying PA levels and have increasingly found their way into clinical...
journal_title:Cardiology
pub_type:
doi:10.1159/000512186
更新日期:2021-01-13 00:00:00
abstract::Fractional flow reserve (FFR) may not be immune from hemodynamic perturbations caused by both vessel and lesion related factors. The aim of this study was to investigate the impact of plaque- and vessel wall-related features of vulnerability on the hemodynamic effect of intermediate coronary stenoses. Methods and Resu...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000508885
更新日期:2021-01-01 00:00:00
abstract::The radial artery is the preferred access site for cardiac catheterization because of patient comfort, early ambulation, and improved survival in acute coronary syndromes, when compared to the femoral artery route. However, it is associated with a high radial artery occlusion (RAO) rate, and patent haemostasis which c...
journal_title:Cardiology
pub_type:
doi:10.1159/000510293
更新日期:2020-12-16 00:00:00
abstract:BACKGROUND:The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is largely unknown. Proteomics offers an approach to overview the molecular activities and signal transduction pathways involved in specific disease processes. OBJECTIVES:In this study, the expression of proteins in endarterectomized ...
journal_title:Cardiology
pub_type: 新闻
doi:10.1159/000502831
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Digital health is rapidly entering clinical practice in cardiology. Estonia is one of the leading nations in implementing digital nationwide solutions. Recently, the European Society of Cardiology organized the 1st Summit on Digital Health in Tallinn, which provided the opportunity to discuss various aspects...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000504564
更新日期:2020-01-01 00:00:00
abstract::Type 2 diabetes mellitus (T2DM) and heart failure (HF) have a tremendous impact worldwide, markedly reducing life-expectancy and quality of life. It is now known that each disease represents a risk factor for the other. Moreover, when they are combined, the prognosis is significantly worse. Until recently, these patho...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000504694
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:End-stage renal disease is associated with cardiac remodeling, which is partly reversible after kidney transplantation (KT). We aimed to determine the association of cardiovascular comorbidities or kidney-related factors with cardiac reverse remodeling after KT. METHODS:We performed echocardiography in 56 p...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000504381
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:A significant number of heart failure (HF) patients with reduced left ventricular ejection fraction (LVEF) experience ventricular function recovery during follow-up. We studied the variables associated with LVEF recovery in patients treated with sacubitril/valsartan (SV) in clinical practice. METHODS:We ana...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000505148
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:There is no consensus regarding the natural history of rheumatic mitral stenosis (MS) among adults presenting with nonsevere disease. This study aims to describe the progression of stenosis among adult rheumatic MS patients, to identify predictive factors for progression, and to assess the incidence of com...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000505481
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:J-point elevation in the inferior and/or lateral leads is associated with an increased incidence of sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HCM), although the exact underlying mechanism is not known. As severe left ventricular hypertrophy and late gadolinium enhancement (LGE) are important...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000505639
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The value of glycosylated hemoglobin (HbA1c) as a surrogate marker for the prevention of cardiovascular outcomes on antidiabetic drugs is debated. The 2008 FDA guidance led to multiple large clinical trials to evaluate the effect of new antidiabetic drugs versus placebo on major adverse cardia...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000506004
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Atrial fibrosis plays a critical role in atrial fibrillation (AF). A key event in the pathogenesis of fibrosis is the activation of fibroblasts (FBs) into myofibroblasts (MFBs). Paracrine factors released from MFBs lead to ion channel expression changes in cardiomyocytes (CMs). Downregulation of L-type calciu...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000505641
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Atrial fibrosis plays a critical role in the occurrence and maintenance of atrial fibrillation. The role of TGF-β1 in mediating atrial fibrosis is well documented. The β-galactoside-binding lectin galectin-3 (Gal-3) is mainly produced by macrophages in biological events such as inflammation and angiogenesis....
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000506072
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To assess improvement in predictive performance of Global Registry of Acute Coronary Events risk score (GRS) by addition of a glucose matrix. METHODS:1,056 acute coronary syndrome (ACS) survivors without known diabetes had pre-discharge fasting (FPG) and 2-h post-load plasma glucose (2h-PG) measured. GRS was...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000509180
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:There are several electrocardiographic algorithms to predict the origin of idiopathic outflow tract ventricular arrhythmias (OT-VAs). This study aimed to develop a more accurate and efficient stepwise electrocardiographic algorithm to discriminate left ventricular outflow tract (LVOT) from right ventricular ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000507360
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The association between height and cardiovascular disease (CVD) has been reported in epidemiological studies for decades; however, the mechanism for this relationship is still unclear. We previously reported that dyslipidemia was associated with adult height in Korean men without CVD. OBJECTIVES:This study ...
journal_title:Cardiology
pub_type: 新闻
doi:10.1159/000509631
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:COVID-19 is a rapidly growing infectious disease that represents an immediate threat for the health of millions of people around the world, both in direct and indirect ways. CASE PRESENTATION:In the present report we describe the development of stress cardiomyopathy in a patient who was overwhelmingly str...
journal_title:Cardiology
pub_type:
doi:10.1159/000511450
更新日期:2020-01-01 00:00:00
abstract::Heart failure (HF) with reduced ejection fraction (HFrEF) has a well-known epidemic relevance in western countries. It affects up to 1-2% of patients > 60 years and reaches a prevalence of 12% in octogenarian patients. The role of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitive troponin I (hsT...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000488640
更新日期:2019-01-01 00:00:00
abstract::Patients with chronic kidney disease (CKD) have an increased risk of adverse cardiovascular/cerebrovascular events. The aim of this study is to clarify whether stress myocardial perfusion single-photon emission computed tomography (SPECT) could predict cardiovascular/cerebrovascular events. In the Gunma-CKD SPECT Stud...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000496330
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Women are underrepresented in sacubitril/valsartan (SV) clinical trials. The aim of this study was to assess sex-specific differences in efficacy, tolerability, and safety of SV in real-world heart failure with reduced ejection fraction (HFrEF) patients. METHODS:A prospective registry in 10 centers includin...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000498984
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:This study sought to assess the impact of treatment with digitalis on recurrences of ventricular tachyarrhythmias in implantable cardioverter defibrillator (ICD) recipients with atrial fibrillation (AF) and heart failure (HF). BACKGROUND:The data regarding outcomes of digitalis therapy in ICD recipients are ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000497271
更新日期:2019-01-01 00:00:00
abstract:AIM:Hyponatremia is very often associated with renal disease in patients with heart failure (HF) and, when present, determines a poor outcome. We investigated the role of hyponatremia in HF patients in whom the presence or absence renal insufficiency was accurately predefined. METHODS:This was a cohort study based on ...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000502566
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Multiple studies have quantified the relationship between aortic size and risk of dissection. However, these studies estimated the risk of dissection without accounting for any increase in aortic size from the dissection process itself. OBJECTIVES:This study aims to compare aortic size before and after diss...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000481930
更新日期:2018-01-01 00:00:00
abstract::Hybrid coronary revascularization (HCR) combines surgical bypass with percutaneous coronary intervention (PCI) performed either during the same procedure or in a staged approach within 60 days. Coronary artery bypass grafting using the left internal mammary artery (LIMA) has shown excellent long-term patency with impr...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000488190
更新日期:2018-01-01 00:00:00
abstract::The aim of our study was to examine the pathophysiology of ST depression (STD) in leads V1-V3 in the setting of inferior ST elevation myocardial infarction (iSTEMI) through the perspective of cardiac magnetic resonance (CMR). METHODS:Differences in myocardial area at risk (MaR), infarct size, ejection fraction and my...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000491745
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To study the care pathway effect on the percentage of patients with ST-elevation myocardial infarction -(STEMI) receiving timely coronary reperfusion and the percentage of STEMI patients receiving optimal secondary prevention. METHODS:A care pathway was implemented by the Collaborative Model for Achieving B...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000488932
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To substitute the stroke volume index (SVi) with flow rate (FR) in the hemodynamic classification of severe aortic stenosis (AS) with preserved ejection fraction (EF), in order to evaluate its prognostic value. METHODS:A total of 529 patients (78.8 ± 9.8 years old, 44.1% males) with isolated severe AS (aort...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000493165
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:Although dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is currently recommended in patients after transcatheter aortic valve implantation (TAVI), this practice is not supported by sufficient evidence. This study was performed to compare DAPT to single antiplatelet therapy (SAPT). METHODS:An ...
journal_title:Cardiology
pub_type: 杂志文章,meta分析
doi:10.1159/000490307
更新日期:2018-01-01 00:00:00
abstract::Coronary calcification is a hard challenge for the interventional cardiologist, as it is associated with incomplete stent expansion and frequently stent failure. In recent years, innovative techniques, such as rotational atherectomy, have been developed to treat coronary calcification. However, these are burdened with...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000495177
更新日期:2018-01-01 00:00:00
abstract::The subcutaneous implantable cardioverter defibrillator (S-ICD) registry included very few patients with a body mass index (BMI) greater than 40. We present a case of a 40-year-old male with a BMI of 44 and ejection fraction of 25% who underwent S-ICD implantation for primary prevention of sudden cardiac death in the ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000447484
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Red blood cell microparticles (RBCm) have potential adverse vascular effects and they have been shown to be elevated in ST elevation myocardial infarction (STEMI). The purpose of this study is to investigate their relationship with biochemical infarct size. METHODS:RBCm were quantified with flow cytometry i...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000447625
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Studies evaluating the long-term outcome of adults with ventricular septal defect (VSD) are important to inform patients about prognosis. This study investigated the long-term outcome of patients with perimembranous VSD (pmVSD) followed in the Belgian Registry on Adult Congenital Heart Disease. METHODS:All ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000448513
更新日期:2017-01-01 00:00:00
abstract::Heart failure with a preserved ejection fraction (HFpEF) is increasingly prevalent and a leading cause of morbidity and mortality worldwide. HFpEF has a complex pathophysiology, with recent evidence suggesting that an interaction of cardiovascular and noncardiovascular comorbidities (e.g. obesity, hypertension, diabet...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000450573
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Recent research has indicated that red blood cell distribution width (RDW) is associated with the prognosis of cardiovascular diseases such as chronic heart failure and coronary heart disease. We aimed to study the predictive value of RDW for bleeding events in patients with nonvalvular atrial fibrillation (...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000449461
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Angiotensin II (Ang II) plays an important role in cardiovascular disease. It also leads to the activation of coagulation. The coagulation protease thrombin induces cellular responses by activating protease-activated receptor 1 (PAR-1). We investigated whether PAR-1 contributes to Ang II-induced cardiovascul...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000452269
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:The present study aimed to evaluate the hypertension status of community residents, analyze environmental and epigenetic factors, and propose prevention measures for hypertension. METHODS:In our study, different methylation levels were distinguished utilizing melting temperature (Tm) values in both the case...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000458520
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Transforming growth factor β1 (TGF-β1) is the major cytokine for stimulating endothelial cells (ECs) to transdifferentiate to mesenchymal cells (MCs) in the process known as endothelial-to-mesenchymal transition (EndMT). Recently, TGF-β1-induced EndMT has been implicated in the pathogenesis of atherosclerosis...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000464321
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Cardiomyopathy (CMP) in children is a clinically and genetically heterogeneous group of disorders. Disease-associated mutations have been identified in more than 50 genes. Recently, mutations in the mitochondrial tRNA processing gene, ELAC2, were reported to be associated with the recessively inherited form o...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000465516
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVES:Retropharyngeal lesions are often associated with Kawasaki disease (KD). A 4-year-old male first presented a peritonsillar and retropharyngeal abscess-like lesion. Surgical tonsillectomy was performed to avoid a risk of mediastinal abscess, but he fulfilled the diagnostic criteria of KD after the operation. ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000467388
更新日期:2017-01-01 00:00:00
abstract::Acute stent thrombosis (AST) is a rare but life-threatening complication of coronary artery stenting. AST remains a challenging task for cardiologists, despite the application of modern procedural techniques and dual-antiplatelet therapy strategies as well as improved understanding of the underlying pathophysiology. T...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000464404
更新日期:2017-01-01 00:00:00