The "Burden" of Malignancy in a Tertiary Hospital Intensive Cardiovascular Care Unit.

Abstract:

OBJECTIVES:During the past decade, the most common causes of mortality and morbidity were cardiovascular diseases and malignancies. The aim of the current study was to describe the incidence, course of admission, and short-term (30-day) prognosis of patients with and without malignancy, admitted to a tertiary center intensive cardiovascular care unit (ICCU). METHODS:A prospective observational study of 2,259 patients admitted to the ICCU was conducted between January 2014 and December 2015. Patients with malignancies (n = 256) were divided into 2 groups: those with solid and those with homogenous tumors. RESULTS:The time of diagnosis was categorized into 3 patient groups: recent (<6 months), 59 patients (23%); late (6-24 months), 49 patients (19%), and very late (>24 months), 148 patients (58%). Those with a history of malignancy were older (73 ± 12 vs. 64 ± 15, p < 0.001) and were more likely to be female (p = 0.002). After using a multivariate logistic regression model analysis, no differences were found in therapeutic interventions and clinical outcomes, including major bleeding and acute renal failure, between patients with and without malignancies. CONCLUSIONS:Patients with a malignancy comprised about 10% of the entire ICCU population. While mortality was independently associated with advanced age, renal failure, and a diagnosis of ST-elevation myocardial infarction, malignancy alone was not found to be independently associated with a higher mortality rate at 30 days of follow-up.

journal_name

Cardiology

journal_title

Cardiology

authors

Mazin I,Matetzky S,Shemer L,Fourey D,Fefer P,Segev A,Abu-Much A,Beigel R,Asher E,Platelets and Thrombosis in Sheba (PLATIS) Study Group.

doi

10.1159/000477840

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

195-199

issue

3

eissn

0008-6312

issn

1421-9751

pii

000477840

journal_volume

138

pub_type

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