Abstract:
:Angina pectoris due to coronary artery disease is a common manifestation of myocardial ischemia. Reduction of oxygen demand (beta-blockers) and relief of coronary vasoconstriction (calcium blocker or nitrate) are additive approaches to controlling ischemia. Risk factor reduction may improve coronary vascular physiology, and ASA reduces the likelihood of thrombosis and myocardial infarction. It is still unclear whether reduction of angina reduces cardiac morbidity and/or mortality. In the Asymptomatic Cardiac Ischemia Pilot Study (ACIP) and Total Ischemic Burden Bisoprolol Study (TIBBS) trials, data suggest benefit from reducing myocardial ischemia. Thus control of angina pectoris is a major goal of the treatment of coronary artery disease.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Parmley WWdoi
10.1159/000177503subject
Has Abstractpub_date
1997-01-01 00:00:00pages
27-31eissn
0008-6312issn
1421-9751journal_volume
88 Suppl 3pub_type
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