Abstract:
:The presence of cardiac proteins in serum has been related to ischemic heart diseases such as acute myocardial infarction and angina pectoris, which are more frequent in non-insulin-dependent diabetic patients. Silent myocardial ischemia, which is also more frequent in these patients, occurs in association with autonomic dysfunction. We used Western blot analysis to search the myocardial protein alpha-actinin in sera from non-insulin-dependent diabetic patients with or without autonomic dysfunction. Of the 24 diabetic patients with neuropathy, 18 were positive for circulating alpha-actinin; this protein was found in only 1 of the 22 diabetic patients without neuropathy. Our results showed a significant correlation between non-insulin-dependent diabetic patients with neuropathy and detectable circulating alpha-actinin in serum, and suggest that the determination by immunoblotting of serum alpha-actinin in these patients may be an effective method to detect myocardial cell impairment, and to identify diabetic patients that may need special consideration.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Prados J,Melguizo C,Arånega AE,Escobar-Jimenez F,Cobo V,Aránega Adoi
10.1159/000177106subject
Has Abstractpub_date
1996-07-01 00:00:00pages
283-6issue
4eissn
0008-6312issn
1421-9751journal_volume
87pub_type
杂志文章相关文献
CARDIOLOGY文献大全abstract:OBJECTIVE:Recent studies have shown that high-sensitivity C-reactive protein (hs-CRP) measured before cardioversion (CV) plays a significant role in predicting atrial fibrillation (AF) relapse. The time course of changes in hs-CRP after successful electrical CV remains controversial. The aim of the present study was to...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000327998
更新日期:2011-01-01 00:00:00
abstract::Electrocardiographic responses of body-builders and control subjects obtained during the performance of static and dynamic Valsalva maneuvers were studied to determine the causative stimulus for wandering pacemaker activity. The incidence of shifting or wandering pacemaker was nearly double in body-builders, suggestin...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173486
更新日期:1982-01-01 00:00:00
abstract::The early administration of nitrates in acute myocardial infarction (AMI) may lower myocardial oxygen demand and increase blood supply to the ischemic myocardium. Actually, nitrates are the drugs most largely used in AMI patients, but no definite proof of their clinical benefits had been reported before GISSI 3 and IS...
journal_title:Cardiology
pub_type: 杂志文章,meta分析
doi:10.1159/000176441
更新日期:1994-01-01 00:00:00
abstract::A pulmonary artery aneurysm is defined as pulmonary artery dilatation >4 cm. Pulmonary artery aneurysms are rare findings and are usually not associated with chest pain. This is the first report of a case of pulmonary artery aneurysm causing chest pain in a patient with Noonan's syndrome. Chest X-ray showed cardiomega...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000112408
更新日期:2008-01-01 00:00:00
abstract::Coronary arteries in diabetic patients appear to be narrower than in normal subjects, but this has not been examined systematically. To investigate this hypothesis we reviewed the data of 711 consecutive patients with angiographically 'normal coronary arteries'. Excluded were patients with valvular, myocardial or peri...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006764
更新日期:1998-01-01 00:00:00
abstract::Cell membrane phospholipids, including platelet-activating factor (PAF), participate in the pathogenesis of acute myocardial infarction (AMI). The plasma level of PAF acetylhydrolase (AH) was determined in 18 patients at presentation with AMI before thrombolysis, and the administration of adjunctive therapy, and compa...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000006831
更新日期:1998-10-01 00:00:00
abstract::The natriuretic effects of furosemide and the long-acting loop diuretic torasemide have been compared in patients with chronic renal failure with and without nephrotic syndrome. In patients with chronic renal failure without nephrotic syndrome, furosemide and torasemide exerted similar natriuretic activity. In patient...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176469
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Despite recent advances in cardiovascular surgery, hyperbilirubinemia after heart valve surgery occurs often and the mechanism is not well clarified. We evaluated the incidence and nature of postoperative hyperbilirubinemia in heart valve surgery patients to analyze its risk factors and to identify its clini...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000338142
更新日期:2012-01-01 00:00:00
abstract::Third degree atrioventricular (AV) heart block with severe Adams-Stokes attacks in 3 patients with Lyme borreliosis is described. All patients had similar clinical manifestations: previously healthy, they experience syncope as an abrupt onset of the disease. Data on skin changes--erythema migrans--was subsequently obt...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177064
更新日期:1996-01-01 00:00:00
abstract::Several lines of evidence have shown that viral infections are capable of causing coronary spasm and precipitating or mimicking clinical myocardial infarction. Here we report the case of a 41-year-old woman with recurrent angina who was admitted to our hospital because of ventricular tachycardia. Laboratory examinatio...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006987
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVES:During the past decade, the most common causes of mortality and morbidity were cardiovascular diseases and malignancies. The aim of the current study was to describe the incidence, course of admission, and short-term (30-day) prognosis of patients with and without malignancy, admitted to a tertiary center in...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000477840
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:The PRevention of cArdiac Dysfunction during Adjuvant breast cancer therapy (PRADA) study is a randomized, placebo-controlled, double-blind trial to determine whether angiotensin receptor blockers (ARB), or beta-blockers or their combination may prevent the development of left ventricular (LV) dysfunction in ...
journal_title:Cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1159/000343622
更新日期:2012-01-01 00:00:00
abstract::We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). T...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000088106
更新日期:2005-01-01 00:00:00
abstract::Various aspects of carbohydrate and lipid metabolism were studied in two groups of patients with mild hypertension before and after 6 months' treatment with either lisinopril (n = 10) or hydrochlorothiazide (n = 10). A significant reduction of arterial blood pressure was seen after both treatment regimens. Circulating...
journal_title:Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000175965
更新日期:1993-01-01 00:00:00
abstract::The severe teratogenic side effects of thalidomide led to its well-publicized withdrawal in the 1970s, but as it is cautiously being reintroduced into clinical use, new adverse effects are being described. A 65-year-old male with multiple myeloma received chemotherapy which included cyclophosphamide, thalidomide and d...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000348367
更新日期:2013-01-01 00:00:00
abstract::Sudden cardiac death in athletes, although relatively uncommon, is a well-recognized condition generally associated with some congenital abnormalities. It, however, continues to be of vast interest to the public as athletes are seen as a distinct group of individuals who are especially able to tolerate more intense ph...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000074812
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To assess whether postoperative quality of life (QOL) for composite aortic root replacement patients differs according to whether it is based on the use of mechanical valves or bioprosthetic valves. METHODS:The study included 146 consecutive patients who underwent composite aortic root replacement at our ins...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000438783
更新日期:2016-01-01 00:00:00
abstract::Aortic valve myxoma is an extremely rare cardiac tumour. We describe a 60-year-old woman found to have an aortic valve myxoma and a patent foramen ovale (PFO) presenting as a stroke. In view of the recurrent cerebral ischaemic events, the aortic valve myxoma was surgically removed and the PFO was closed. To the best o...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000327081
更新日期:2011-01-01 00:00:00
abstract::Heart failure is a huge healthcare issue not only for clinicians but for healthcare managers also, with increasing pressure to demonstrate the cost-effectiveness of therapies especially for common chronic conditions. The cost-effectiveness of heart failure treatments relate to their effects on the progression of the d...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000177166
更新日期:1996-01-01 00:00:00
abstract:OBJECTIVE:To compare all-cause mortality in JUPITER with other statin trials at 21 months of follow-up. BACKGROUND:Outcome advantages including all-cause mortality reduction yielded from the JUPITER trial support aggressive use of rosuvastatin and, perhaps by extension, other statins for primary prevention. Despite en...
journal_title:Cardiology
pub_type: 社论
doi:10.1159/000330507
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To study the care pathway effect on the percentage of patients with ST-elevation myocardial infarction -(STEMI) receiving timely coronary reperfusion and the percentage of STEMI patients receiving optimal secondary prevention. METHODS:A care pathway was implemented by the Collaborative Model for Achieving B...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000488932
更新日期:2018-01-01 00:00:00
abstract::(1) 36 outpatients with a manifest orthostatic syndrome were the subject of a double-blind study to investigate the influence of Dihydergot and a placebo over a 4-week period. (2) In the majority of subjects, the dosage was 1 tablet (2.5 mg) 3 times a day. (3) In the test group with Dihydergot (17 subjects), a normali...
journal_title:Cardiology
pub_type: 临床试验,杂志文章
doi:10.1159/000169827
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVES:To explore the relation between the baseline aortic valve gradient (AVG) as a continuous variable and clinical outcomes following transcatheter aortic valve implantation (TAVI) in general and specifically in patients with high-gradient aortic stenosis (AS). METHODS:We reviewed 317 consecutive patients who u...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000444007
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:It was the purpose of this study to demonstrate the feasibility of performing coronary artery flow and coronary flow reserve (CFR) measurements in normal human volunteers using a magnetic resonance (MR) phase contrast technique. MATERIALS AND METHODS:Coronary flow rate, flow velocity, peak flow and CFR were de...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177314
更新日期:1997-01-01 00:00:00
abstract::Lipid-lowering agents are used with the purpose of ameliorating hyperlipoproteinemias, in order to prevent arterial disease. Lipid-lowering drugs can be classified into absorbable agents and into nonabsorbable compounds, acting within the gastrointestinal lumen. Absorbable drugs (fibric acids, nicotinic acid, probucol...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000174789
更新日期:1991-01-01 00:00:00
abstract::A new method is presented for decomposition of 99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. Th...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173943
更新日期:1985-01-01 00:00:00
abstract:BACKGROUND:Digital health is rapidly entering clinical practice in cardiology. Estonia is one of the leading nations in implementing digital nationwide solutions. Recently, the European Society of Cardiology organized the 1st Summit on Digital Health in Tallinn, which provided the opportunity to discuss various aspects...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000504564
更新日期:2020-01-01 00:00:00
abstract::The spectrum of patients operated on without preoperative catheterization and angiography, the accuracy of echocardiographic diagnosis and its impact on the results of surgical treatment were prospectively assessed in 2,788 children consecutively operated for congenital heart defects (CHD) between 1986 and 1992. The o...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176928
更新日期:1995-01-01 00:00:00
abstract:CONTEXT:Oral reversible platelet P2Y12 receptor inhibitors (ticagrelor and elinogrel) cause double-digit rates of dyspnea, while irreversible oral antiplatelet drugs (aspirin, ticlopidoine, clopidogrel, and prasugrel) or intravenous glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, or tirofiban) do not increas...
journal_title:Cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000354876
更新日期:2014-01-01 00:00:00
abstract::Patients with Marfan syndrome are at risk for ascending aortic dilation and dissection at the level of the aortic sinuses, making aortic root and valve replacement common. Patients undergoing an aortic root replacement with concomitant replacement of the aortic valve with a bioprosthesis (Bio-Bentall) are predisposed ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000357265
更新日期:2014-01-01 00:00:00