Dyspnea and reversibility of antiplatelet agents: ticagrelor, elinogrel, cangrelor, and beyond.

abstract：:Fenofibrate is a fibric acid derivative with enhanced potency and specificity of action on lipids. Preclinical toxicology reveals minimal toxic effects; dose-related changes occurred seldom, with only hepatic effects in rodents (mainly enzyme changes), some renal effects in dogs, and no reactions in monkeys. Teratogen...

journal_title：Cardiology

authors： Roberts WC

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:This study sought to assess the impact of treatment with digitalis on recurrences of ventricular tachyarrhythmias in implantable cardioverter defibrillator (ICD) recipients with atrial fibrillation (AF) and heart failure (HF). BACKGROUND:The data regarding outcomes of digitalis therapy in ICD recipients are ...

journal_title：Cardiology

authors： Schupp T,Behnes M,Weiss C,Nienaber C,Reiser L,Bollow A,Taton G,Reichelt T,Ellguth D,Engelke N,Rusnak J,Weidner K,Akin M,Mashayekhi K,Borggrefe M,Akin I

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that a lower lymphocyte ratio (Ly%) in the white blood cell (WBC) differential count is related to worse outcomes in patients with acute heart failure (AHF) and other cardiovascular disorders. METHODS:In the Pre-RELAX-AHF study, 234 patients with AHF, systolic blood pressure ...

journal_title：Cardiology

authors： Milo-Cotter O,Teerlink JR,Metra M,Felker GM,Ponikowski P,Voors AA,Edwards C,Weatherley BD,Greenberg B,Filippatos G,Unemori E,Teichman SL,Cotter G

更新日期：2010-01-01 00:00:00

abstract：:To study the effects of steroid elution on chronic pacing threshold and impedance, a 4-mm2 surface area lead with steroid (030-368, Telectronics; n = 9) was compared to the same lead without steroid (030-359, Telectronics; n = 9) 3 months after implantation. The pulse duration thresholds of the steroid lead were signi...

journal_title：Cardiology

authors： Schuchert A,Kuck KH

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:This study aimed to investigate the feasibility and effects of intramuscular injections of autologous bone marrow cells (BMC) combined with off-pump coronary artery bypass grafts (OPCAB) on improving cardiac function in chronic myocardial infarction patients. METHODS:Ninety patients with chronic myocardial ...

journal_title：Cardiology

authors： Wang H,Wang Z,Jiang H,Ma D,Zhou W,Zhang G,Chen W,Huang J,Liu Y

更新日期：2015-01-01 00:00:00

abstract：:The primary aim of the management of hypertension should be to prevent coronary heart disease. Antihypertensive treatment should have a beneficial effect on the risk factors associated with coronary heart disease, particularly hypertension, dyslipidemia, hyperinsulinemia, and/or glucose intolerance. Other important ri...

journal_title：Cardiology

authors： Weidmann P

更新日期：1994-01-01 00:00:00

abstract：:Limited prospective data are available regarding the influence of pacemaker leads on tricuspid valve function. To examine the true incidence of these complications, 35 patients were prospectively examined by two-dimensional and Doppler echocardiography before and after implantation of either a permanent pacemaker or a...

journal_title：Cardiology

authors： Leibowitz DW,Rosenheck S,Pollak A,Geist M,Gilon D

更新日期：2000-01-01 00:00:00

abstract：:In order to compare the acute hemodynamic effects of digoxin (0.01 mg/kg) and enoximone (1 mg/kg), a phosphodiesterase inhibitor inotropic agent, in severe chronic congestive heart failure, 8 patients (male, mean age 56.7 years, sinus rhythm) were investigated with a randomized cross-over study. Peak effect of enoximo...

journal_title：Cardiology

authors： Casella G,Cantelli I,Pavesi PC,Barbato G,Bracchetti D

更新日期：1994-01-01 00:00:00

abstract：:We evaluated the efficacy and safety of daily administration of gallopamil 150 mg/day and its effects on myocardial perfusion in a medium-term, randomized, double-blind, cross-over, placebo-controlled trial. We studied 19 patients (17 males and 2 females; mean age 57 +/- 6.8 years) with stable effort angina, angiograp...

journal_title：Cardiology

authors： Acanfora D,Vitale DF,Rengo C,Iannuzzi GL,Furgi G,Picone C,Rossi M,Trojano L,Rengo F

更新日期：1997-07-01 00:00:00

abstract：:CD18 integrins mediate leucocyte adhesion to vascular endothelium. This represents the initial step in inflammatory cell infiltration following myocardial necrosis. The current study assessed whether the expression of these rapidly activated and readily measured adhesion receptors on circulating neutrophils would refl...

journal_title：Cardiology

authors： Hillis G,Taggart P,Dalsey W,Mangione A,Ma XL

更新日期：2001-01-01 00:00:00

abstract：:Review of a longitudinal study of the effects of 40 mg of propranolol orally in 14 patients with coronary heart disease demonstrated a minor but not statistically significant change in the relationship of percentage of maximal oxygen uptake to percentage of maximal heart rate. In a cross-sectional comparison of severa...

journal_title：Cardiology

authors： Hossack KF,Bruce RA,Clarke LJ

更新日期：1980-01-01 00:00:00

abstract：PURPOSE:It was the purpose of this study to demonstrate the feasibility of performing coronary artery flow and coronary flow reserve (CFR) measurements in normal human volunteers using a magnetic resonance (MR) phase contrast technique. MATERIALS AND METHODS:Coronary flow rate, flow velocity, peak flow and CFR were de...

journal_title：Cardiology

authors： Grist TM,Polzin JA,Bianco JA,Foo TK,Bernstein MA,Mistretta CM

更新日期：1997-01-01 00:00:00

abstract：:We report the case of a man whose high-density lipoprotein cholesterol (HDL-C) and the ratios of total cholesterol to HDL-C and low-density lipoprotein cholesterol to HDL-C worsened dramatically during pravastatin treatment. After 3 years, pravastatin was replaced by fenofibrate. The result was spectacular. The HDL-C ...

journal_title：Cardiology

authors： Devroey D,Betz W,Coigniez P,Lauwers R,Velkeniers B

更新日期：2002-01-01 00:00:00

abstract：:Renal function in the basal state and after sodium load has been investigated in 21 borderline, hypertensive, first-degree relatives of established hypertensives and in 21 age- and sex-matched, normal subjects with no family history of hypertension. During intravenous infusion of inulin and p-aminohippurate in saline,...

journal_title：Cardiology

authors： Trimarco B,De Simone A,Volpe M,Ricciardelli B,Ungaro B,Sacca L,Rengo F,Condorelli M

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVES:Studies evaluating the long-term outcome of adults with ventricular septal defect (VSD) are important to inform patients about prognosis. This study investigated the long-term outcome of patients with perimembranous VSD (pmVSD) followed in the Belgian Registry on Adult Congenital Heart Disease. METHODS:All ...

journal_title：Cardiology

authors： Gabriels C,De Backer J,Pasquet A,Paelinck BP,Morissens M,Helsen F,Van De Bruaene A,Budts W

更新日期：2017-01-01 00:00:00

abstract：:Valsartan is a specific angiotensin II receptor antagonist with high selectivity for the AT(1) receptor subtype. After oral administration of single or repeated once-daily doses, valsartan 40-80 mg inhibits the pressor response to angiotensin II for 24 hours. In patients with mild-to-moderate hypertension, efficacy of...

journal_title：Cardiology

authors： McInnes GT

更新日期：1999-01-01 00:00:00

abstract：:A 56-year-old woman, who had received an aortic valve replacement suffered from complete left bundle branch block and advanced atrioventricular block. On the basis of marked systemic inflammatory findings on admission and histopathological findings on previous cardiac surgery, this patient was considered to have condu...

journal_title：Cardiology

authors： Naitoh M,Chino M,Sakai T,Saitoh S,Ohkura M,Nishikawa K

更新日期：1990-01-01 00:00:00

abstract：:Fifty percent of patients with dilated cardiomyopathy die within 5 years of diagnosis. Syncope is known to be a predictor of poor outcome in patients with advanced heart failure. To assess the risk of patients with dilated cardiomyopathy with a history of syncope during standard medical treatment we compared this grou...

journal_title：Cardiology

authors： Fruhwald FM,Eber B,Schumacher M,Zweiker R,Watzinger N,Klein WW

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVE:Niacin is underutilized due to flushing, which occurs in over 90% of niacin-treated patients. Laropiprant (LRPT) reduces flushing associated with niacin. This study compared flushing with a combination tablet of extended-release (ER) niacin (ERN)/LRPT to niacin ER (N-ER; without LRPT) during the first week of...

journal_title：Cardiology

authors： Kush D,Hu DY,Ye P,Kim HS,Chen E,Sirah W,McCrary Sisk C,Paolini JF,Maccubbin D

更新日期：2009-01-01 00:00:00

abstract：:Carvedilol is a multiple-action cardiovascular agent that is a nonselective beta-adrenoceptor antagonist and a vasodilator. beta-Adrenoceptor antagonists reduce myocardial work, secondary to reductions in heart rate and contractility, both in animals and in humans. For these reasons, carvedilol may improve survival of...

journal_title：Cardiology

authors： Ruffolo RR Jr,Bril A,Feuerstein GZ

更新日期：1993-01-01 00:00:00

abstract：:Atrial fibrillation is a complex disease. Its etiologies are diverse and genetic factors may also contribute to this disease. With the advent of modern molecular biology technology, it is now possible to explore the genetic components in the pathogenesis of atrial fibrillation. Past molecular genetic studies on atrial...

journal_title：Cardiology

authors： Lai LP,Lin JL,Huang SK

更新日期：2003-01-01 00:00:00

abstract：:The spectrum of patients operated on without preoperative catheterization and angiography, the accuracy of echocardiographic diagnosis and its impact on the results of surgical treatment were prospectively assessed in 2,788 children consecutively operated for congenital heart defects (CHD) between 1986 and 1992. The o...

journal_title：Cardiology

authors： Marek J,Skovránek J,Hucín B,Chaloupecký V,Tax P,Reich O,Samánek M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The shift toward a preventative approach in medical aftercare of congenital heart disease (CHD) patients has led to encouragement of regular physical activity (PA) in this patient population. Objective measures are crucial in accurately displaying PA levels and have increasingly found their way into clinical...

journal_title：Cardiology

authors： Brudy L,Meyer M,Garcia-Cuenllas L,Oberhoffer R,Hager A,Ewert P,Müller J

更新日期：2021-01-13 00:00:00

abstract：:Aortic dissection is accompanied by fever in about one third of the patients. However, fever of unknown origin as the predominant manifestation of aortic dissection seems to be extremely rare. A review of the English literature revealed only 3 patients characterized by fever as the principal sign of aortic dissection....

journal_title：Cardiology

authors： Giladi M,Pines A,Averbuch M,Hershkoviz R,Sherez J,Levo Y

更新日期：1991-01-01 00:00:00

abstract：:Patients with coronary artery disease can exhibit substantial vascular involvement; and vascular patients have a high incidence of coronary disease. Combined coronary artery bypass grafting (CABG) and treatment of extracranial cerebrovascular disease was performed in 52 patients, presenting strong indications for surg...

journal_title：Cardiology

authors： Carrel T,Stillhard G,Turina M

更新日期：1992-01-01 00:00:00

abstract：:Low cardiac output in acute heart failure can result in a functional impairment of organs, when tissue hypoxia occurs and cardiogenic shock develops. To restore cardiac output, various forms of therapy can be considered. Fluid replacement is sometimes beneficial in acute situations where oedema can reduce effective pl...

journal_title：Cardiology

authors： Vincent JL,Léon M,Berré J

更新日期：1990-01-01 00:00:00

abstract：:Ventricular assist devices have emerged as the standard of care in treating end-stage heart failure. Their success in bridging patients to transplantation is well documented. The data supporting their ability to bridge patients to recovery is sparser. However, as technology continues to advance, these devices will off...

journal_title：Cardiology

authors： Kherani AR,Maybaum S,Oz MC

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:Bisoprolol, carvedilol and nebivolol have been shown to be effective in the treatment of heart failure. However, the beta-blocking effects of these drugs have never been compared directly. METHODS:Therefore, we performed a randomized, double-blind, placebo-controlled, cross-over trial in 16 healthy males. Su...

journal_title：Cardiology

authors： Stoschitzky K,Stoschitzky G,Brussee H,Bonelli C,Dobnig H

更新日期：2006-01-01 00:00:00

abstract：:The 6-min walk test (6MWT) is a simple and inexpensive exercise test to evaluate physical functional capacity that is widely used in heart failure (HF) patients. With the 6MWT, a distance <350 m is associated with increased mortality in patients with HF, and change in walking distance >50 m is considered clinically re...

journal_title：Cardiology

authors： Sgorbini L,Rossetti A,Galati A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Atrial fibrosis plays a critical role in the occurrence and maintenance of atrial fibrillation. The role of TGF-β1 in mediating atrial fibrosis is well documented. The β-galactoside-binding lectin galectin-3 (Gal-3) is mainly produced by macrophages in biological events such as inflammation and angiogenesis....

journal_title：Cardiology

authors： Xiao M,Zhang M,Bie M,Wang X,Guo J,Xiao H

更新日期：2020-01-01 00:00:00