Rationale and design of the prevention of cardiac dysfunction during an Adjuvant Breast Cancer Therapy (PRADA) Trial.

abstract：:Investigations on orthostatic tolerance and physical fitness prior to and after 6-8 h immersion experiments surprisingly revealed that all untrained subjects endured pre- and postimmersion tilt table tests without subjective complaints, whereas after immersion all trained participants collapsed within the first minute...

journal_title：Cardiology

authors： Stegemann J

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:The landmark Dual Antiplatelet Therapy (DAPT) trial revealed an impressive reduction of stent thrombosis and myocardial infarction after prolonged 30-month DAPT compared to the conventional 12-month regimen. However, aside from the expected extra bleeding risks, more cancers and noncardiovascular deaths (NCV...

journal_title：Cardiology

authors： Serebruany VL,Cherepanov V,Golukhova EZ,Kim MH

更新日期：2015-01-01 00:00:00

abstract：:It is well documented that in the treatment of mild or moderate hypertension selective alpha 1-inhibitors such as doxazosin and prazosin lower blood pressure to approximately the same extent as beta-blockers, diuretics, ACE inhibitors and calcium antagonists. However, treatment with selective alpha 1-inhibitors is als...

journal_title：Cardiology

authors： Lund-Johansen P,Hjermann I,Iversen BM,Thaulow E

更新日期：1993-01-01 00:00:00

abstract：:Renal function in the basal state and after sodium load has been investigated in 21 borderline, hypertensive, first-degree relatives of established hypertensives and in 21 age- and sex-matched, normal subjects with no family history of hypertension. During intravenous infusion of inulin and p-aminohippurate in saline,...

journal_title：Cardiology

authors： Trimarco B,De Simone A,Volpe M,Ricciardelli B,Ungaro B,Sacca L,Rengo F,Condorelli M

更新日期：1982-01-01 00:00:00

abstract：CONTEXT:Oral reversible platelet P2Y12 receptor inhibitors (ticagrelor and elinogrel) cause double-digit rates of dyspnea, while irreversible oral antiplatelet drugs (aspirin, ticlopidoine, clopidogrel, and prasugrel) or intravenous glycoprotein IIb/IIIa inhibitors (abciximab, eptifibatide, or tirofiban) do not increas...

journal_title：Cardiology

authors： Serebruany VL,Sibbing D,DiNicolantonio JJ

更新日期：2014-01-01 00:00:00

abstract：:Renal hemodynamics in essential hypertensives is characterized by an increase in renal vascular resistance (RVR) and a decrease in renal plasma flow (RPF), while glomerular filtration rate (GFR) is either normal or slightly decreased. Filtration fraction (FF) is increased, indicating that vasoconstriction predominantl...

journal_title：Cardiology

authors： Beaufils M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:We undertook this study to assess the relationship between presentation pattern and mortality in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention. METHODS:This registry included 10,455 patients with ACS, of whom 2,853 patients had ST-segment elevation myocardial infa...

journal_title：Cardiology

authors： Ndrepepa G,Mehilli J,Schulz S,Iijima R,Keta D,Byrne RA,Pache J,Seyfarth M,Schömig A,Kastrati A

更新日期：2009-01-01 00:00:00

abstract：:Cell therapies hold the potential for suppression, modification, or cure of disease. Several unique challenges have been recognized as this field has developed. Many of these involve considerations of trial design. This paper summarizes the discussion and suggestions constructed during the 8th Cardiovascular Clinical ...

journal_title：Cardiology

authors： Lewis RM,Gordon DJ,Poole-Wilson PA,Borer JS,Zannad F

更新日期：2008-01-01 00:00:00

abstract：:An anonymous patient perception comprehension and satisfaction questionnaire was sent to 438 patients 1-3 months after they had participated in a clinical cardiovascular trial to examine the level of patient comprehension as perceived by the patient. We compared perceived comprehension in acute (acute myocardial infar...

journal_title：Cardiology

authors： Yuval R,Halon DA,Flugelman MY,Lewis BS

更新日期：2003-01-01 00:00:00

abstract：:This study assessed behavioral activity, dietary and emotional variables among patient cohorts with angina pectoris, atypical chest pain, and no chest pain in whom coronary disease is suspected. Questionnaire responses of 3,899 employed male patients at the time of coronary arteriography were analyzed. Patients with a...

journal_title：Cardiology

authors： Young LD,Barboriak JJ,Anderson AJ

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Most cases of infective endocarditis are caused by nonenterococcal streptococci. The emergence of strains resistant to penicillin is increasingly recognized worldwide. This study sought to assess the effect of penicillin resistance on presentation and outcome of streptococcal endocarditis. METHODS:...

journal_title：Cardiology

authors： Hsu RB,Lin FY

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Atrial fibrosis plays a critical role in atrial fibrillation (AF). A key event in the pathogenesis of fibrosis is the activation of fibroblasts (FBs) into myofibroblasts (MFBs). Paracrine factors released from MFBs lead to ion channel expression changes in cardiomyocytes (CMs). Downregulation of L-type calciu...

journal_title：Cardiology

authors： Li S,Gao Y,Liu Y,Li J,Yang X,Hu R,Liu J,Zhang Y,Zuo K,Li K,Yin X,Chen M,Zhong J,Yang X

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Although dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is currently recommended in patients after transcatheter aortic valve implantation (TAVI), this practice is not supported by sufficient evidence. This study was performed to compare DAPT to single antiplatelet therapy (SAPT). METHODS:An ...

journal_title：Cardiology

authors： Hu X,Yang FY,Wang Y,Zhang Y,Chen M

更新日期：2018-01-01 00:00:00

abstract：:Coarctation of the aorta commonly presents in infancy as congestive heart failure, or later in childhood as hypertension or as a heart murmur. However, we experienced a unique infant case of isolated coarctation presenting with acute decompensation of a dilated cardiomyopathy, which recovered completely 8 months posto...

journal_title：Cardiology

authors： Hwang MS,Chu JJ,Chang YS,Su WJ

更新日期：2006-01-01 00:00:00

abstract：:Fractional flow reserve (FFR) may not be immune from hemodynamic perturbations caused by both vessel and lesion related factors. The aim of this study was to investigate the impact of plaque- and vessel wall-related features of vulnerability on the hemodynamic effect of intermediate coronary stenoses. Methods and Resu...

journal_title：Cardiology

authors： Sezer M,Aslanger E,Cakir O,Atici A,Sezer I,Ozcan A,Umman B,Bugra Z,Umman S

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:To investigate a polymorphism of the apolipoprotein J (APOJ) gene in relation to coronary artery disease (CAD) and lipid variables in a Chinese male population of genetically unrelated individuals. METHODS:In this study, we recruited 126 control male subjects and 237 CAD male patients. CAD was defined as a ...

journal_title：Cardiology

authors： Pan JP,Wei SL,Chiang SC,Lee-Chen GJ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine whether the release by macrophages of matrix metalloproteinase (MMP)-12 and vascular endothelial growth factor (VEGF) - leading to inflammation, matrix degradation and neoangiogenesis - represents an effective pathway that underlies aortic wall remodeling in Stanford typ...

journal_title：Cardiology

authors： Del Porto F,di Gioia C,Tritapepe L,Ferri L,Leopizzi M,Nofroni I,De Santis V,Della Rocca C,Mitterhofer AP,Bruno G,Taurino M,Proietta M

更新日期：2014-01-01 00:00:00

abstract：:Ventricular late potentials are obtained by signal averaging of surface electrocardiograms. Late potentials have been reported to be affected by body size or left ventricular mass. However, the effect of subadipose tissue, which is known to influence QRS amplitudes of surface ECG, on the variables of late potentials h...

journal_title：Cardiology

authors： Masui A,Tsuji H,Tamura K,Sugiura T,Matsui Y,Iwasaka T,Inada M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:It is known that the expression, activity and alternative splicing of Ca2+/calmodulin-dependent protein kinase IIδ (CaMKIIδ) are dysregulated in the cardiac remodeling process. Recently, we found a further signaling pathway, by which dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) regu...

journal_title：Cardiology

authors： Yao J,Qin X,Zhu J,Sheng H

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Digital health is rapidly entering clinical practice in cardiology. Estonia is one of the leading nations in implementing digital nationwide solutions. Recently, the European Society of Cardiology organized the 1st Summit on Digital Health in Tallinn, which provided the opportunity to discuss various aspects...

journal_title：Cardiology

authors： Lotman EM,Viigimaa M

更新日期：2020-01-01 00:00:00

abstract：:Fifty percent of patients with dilated cardiomyopathy die within 5 years of diagnosis. Syncope is known to be a predictor of poor outcome in patients with advanced heart failure. To assess the risk of patients with dilated cardiomyopathy with a history of syncope during standard medical treatment we compared this grou...

journal_title：Cardiology

authors： Fruhwald FM,Eber B,Schumacher M,Zweiker R,Watzinger N,Klein WW

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:End-stage renal disease is associated with cardiac remodeling, which is partly reversible after kidney transplantation (KT). We aimed to determine the association of cardiovascular comorbidities or kidney-related factors with cardiac reverse remodeling after KT. METHODS:We performed echocardiography in 56 p...

journal_title：Cardiology

authors： Kobayashi M,Huttin O,Schikowski J,Bozec E,Zohra L,Frimat L,Girerd N,Girerd S

更新日期：2020-01-01 00:00:00

abstract：:Aortic valve myxoma is an extremely rare cardiac tumour. We describe a 60-year-old woman found to have an aortic valve myxoma and a patent foramen ovale (PFO) presenting as a stroke. In view of the recurrent cerebral ischaemic events, the aortic valve myxoma was surgically removed and the PFO was closed. To the best o...

journal_title：Cardiology

authors： Koyalakonda SP,Mediratta NK,Ball J,Royle M

更新日期：2011-01-01 00:00:00

abstract：:The combination of oral anticoagulation (OAC) and aspirin was the antithrombotic treatment initially adopted after coronary stenting (PCI-S). Although dual antiplatelet therapy with aspirin and a thienopyridine subsequently proved safer and more effective, OAC and aspirin combination is still used in patients with an ...

journal_title：Cardiology

authors： Rubboli A,Milandri M,Castelvetri C,Cosmi B

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:This study sought to elucidate the underlying hemodynamic mechanisms involved in the longitudinal propagation of acute, type-B aortic dissections. METHODS:Three-dimensional patient-specific aortic geometry was reconstructed from computed tomography images of 3 cases, followed by computational fluid dynamic a...

journal_title：Cardiology

authors： Zhang Y,Lu Q,Feng J,Yu P,Zhang S,Teng Z,Gillard JH,Song R,Jing Z

更新日期：2014-01-01 00:00:00

abstract：:Tissue Doppler imaging (TDI) is a new echocardiographic technique employing the Doppler principle to measure the velocity of myocardial segments and other cardiac structures. It is well suited for the measurement of long-axis ventricular function. Impairment of longitudinal myocardial fiber motion is a sensitive marke...

journal_title：Cardiology

authors： Nikitin NP,Witte KK

更新日期：2004-01-01 00:00:00

abstract：:Of 1,125 patients catheterized over a period of 8 years, 68 (6%) had coronary ectasia. Twenty-five of them were catheterized at least twice and constituted the study group. The time between the first and last catheterization ranged from 2 to 8 years (mean +/- SD = 4.2 +/- 1.6). Coronary ectasia was more frequent in ma...

journal_title：Cardiology

authors： Ilia R,Kafri C,Carmel S,Goldfarb B,Gueron M,Battler A

更新日期：1995-01-01 00:00:00

abstract：:The purpose of this study was to elucidate the mechanism that induces an improvement in exercise capacity by nitrates in patients with stable effort angina pectoris. The study population was composed of 19 patients: group A, 10 patients with chronic stable effort angina who had a well-developed coronary collateral cir...

journal_title：Cardiology

authors： Ohno A,Fujita M,Miwa K,Ejiri M,Asanoi H,Sasayama S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:N-terminal pro-B-type natriuretic peptide (NT-proBNP) appears to be a strong risk marker of mortality in patients with acute coronary syndrome. However, little information is available on NT-proBNP as a predictor of long-term serious cardiovascular events beyond that of left ventricular ejection fraction in ...

journal_title：Cardiology

authors： Jonsson G,Abdelnoor M,Landaas S,Muller C,Kjeldsen SE,Os I,Westheim A

更新日期：2006-01-01 00:00:00

abstract：:To investigate the possible role of endothelin in coronary vasoconstriction contributing to the development of myocardial ischemia, plasma endothelin concentrations at rest and during atrial pacing-induced myocardial ischemia have been measured in blood samples drawn from the aorta and coronary sinus in 12 patients wi...

journal_title：Cardiology

authors： Vojácek J,Rohác J,Jindra A Jr,Jáchymová M,Savlíková J,Kmonicek P,Simek S,Horký K

更新日期：1994-01-01 00:00:00