Similarities and differences in design considerations for cell therapy and pharmacologic cardiovascular clinical trials.

abstract：:Fractional flow reserve (FFR) may not be immune from hemodynamic perturbations caused by both vessel and lesion related factors. The aim of this study was to investigate the impact of plaque- and vessel wall-related features of vulnerability on the hemodynamic effect of intermediate coronary stenoses. Methods and Resu...

journal_title：Cardiology

authors： Sezer M,Aslanger E,Cakir O,Atici A,Sezer I,Ozcan A,Umman B,Bugra Z,Umman S

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:To explore the relation between the baseline aortic valve gradient (AVG) as a continuous variable and clinical outcomes following transcatheter aortic valve implantation (TAVI) in general and specifically in patients with high-gradient aortic stenosis (AS). METHODS:We reviewed 317 consecutive patients who u...

journal_title：Cardiology

authors： Witberg G,Barsheshet A,Assali A,Vaknin-Assa H,Shaul AA,Orvin K,Vaturi M,Schwartzenberg S,Shapira Y,Sagie A,Kornowski R

更新日期：2016-01-01 00:00:00

abstract：:Low cardiac output in acute heart failure can result in a functional impairment of organs, when tissue hypoxia occurs and cardiogenic shock develops. To restore cardiac output, various forms of therapy can be considered. Fluid replacement is sometimes beneficial in acute situations where oedema can reduce effective pl...

journal_title：Cardiology

authors： Vincent JL,Léon M,Berré J

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVE:The objective was to evaluate the effect of hormone replacement therapy (HRT) on plasma homocysteine levels in postmenopausal women with coronary artery disease (CAD) and to investigate associations of homocysteine to other cardiovascular risk factors. METHODS:The women in this single-center, controlled, and...

journal_title：Cardiology

authors： Os I,Os A,Sandset PM,Bølling S,Seljeflot I,Djurovic S,Westheim A

更新日期：2002-01-01 00:00:00

abstract：:Pulmonary alveolar microlithiasis (PAM) is a rare disorder of uncertain etiology and pathogenesis that is characterized by tiny calcium phosphate depositions in lung alveoli. Ectopic organ involvement has been reported infrequently. We hereby present a patient with PAM complicated by severe pleural calcification that ...

journal_title：Cardiology

authors： Kacmaz F,Alyan O,Celenk M,Ozdemir O,Turkvatan A,Dogan M,Ilkay E

更新日期：2007-01-01 00:00:00

abstract：:Ventricular late potentials are obtained by signal-averaged surface electrocardiography. Late potentials in normal subjects may be influenced by physiological elements such as gender, height and body mass index. Considering that growth hormone (GH) hypersecretion is able to markedly alter different anthropometric vari...

journal_title：Cardiology

authors： Maffei P,Corfini A,de Carlo E,Martini C,Bozza G,Photiou E,Sicolo N

更新日期：1995-01-01 00:00:00

abstract：:This is the case of a 43-year-old Caucasian man with frequent episodes of paroxysmal atrial fibrillation (AF) and normal resting electrocardiogram (ECG), who fulfilled two minor diagnostic criteria for arrhythmogenic right ventricular cardiomyopathy (ARVC): late potentials by signal-averaged ECG and regional right ven...

journal_title：Cardiology

authors： Anastasakis A,Vouliotis AI,Protonotarios N,Stefanadis C

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Myocardial perfusion imaging (MPI) with positron emission tomography (PET) has advantages over single-photon emission computerized tomography, particularly for women. This investigation was undertaken to define the prognosis of a normal stress PET MPI study in women. METHODS:The cohort comprised 457 women e...

journal_title：Cardiology

authors： Van Tosh A,Supino PG,Nichols KJ,Garza D,Horowitz SF,Reichek N

更新日期：2010-01-01 00:00:00

abstract：:The renin-angiotensin-aldosterone system plays an important role in the development of congestive heart failure (CHF). In patients with chronic heart failure, angiotensin-converting enzyme (ACE) inhibitors, such as captopril, enalapril, and quinapril, have been shown to improve hemodynamics, reduce symptoms of fatigue...

journal_title：Cardiology

authors： Riegger AJ

更新日期：1989-01-01 00:00:00

abstract：:Antihypertensive therapy has been thought to be a life-long treatment. Nevertheless, antihypertensive medication may be discontinued in a substantial proportion of hypertensive patients at least for some time. The current study focused on predictors for the development of elevated blood pressure levels after discontin...

journal_title：Cardiology

authors： Schmieder RE,Rockstroh JK,Gatzka CD,Rüddel H,Schächinger H

更新日期：1997-05-01 00:00:00

abstract：:A 13-year-old girl presented with incessant ventricular tachycardia complicating acute Coxsackie B3 myocarditis. Electrophysiologic assessment revealed that the tachycardia could not be terminated, overdrive suppressed or accelerated by programmed electrical stimulation, but was transiently slowed by intravenous adeno...

journal_title：Cardiology

authors： Tai YT,Lau CP,Fong PC,Li JP,Lee KL

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is largely unknown. Proteomics offers an approach to overview the molecular activities and signal transduction pathways involved in specific disease processes. OBJECTIVES:In this study, the expression of proteins in endarterectomized ...

journal_title：Cardiology

authors： Xi Q,Liu Z,Song Y,Gan H,Huang Z,Luo Q,Zhao Z

更新日期：2020-01-01 00:00:00

abstract：:Arterial blood pressure patterns in 12 men with sleep apnea and arterial hypertension were studied at baseline and after 6 months' therapy with nasal continuous positive airway pressure (nCPAP). Preexisting antihypertensive medication was discontinued 1 week before baseline measurements. Weight did not change during t...

journal_title：Cardiology

authors： Mayer J,Becker H,Brandenburg U,Penzel T,Peter JH,von Wichert P

更新日期：1991-01-01 00:00:00

abstract：:This study was designed to assess the contribution of clinical, electrocardiographic and exercise hemodynamic variables to the prediction of normalization on resting reinjection scintigraphy of persistent thallium-201 (201Tl) myocardial perfusion defects seen with exercise and 2- to 4-hour delayed (redistribution) ima...

journal_title：Cardiology

authors： Shammas NW,Schwartz RG,Pomerantz RM,Murphy GW,Hall WJ

更新日期：1996-05-01 00:00:00

abstract：:Hybrid coronary revascularization (HCR) combines surgical bypass with percutaneous coronary intervention (PCI) performed either during the same procedure or in a staged approach within 60 days. Coronary artery bypass grafting using the left internal mammary artery (LIMA) has shown excellent long-term patency with impr...

journal_title：Cardiology

authors： Saha T,Naqvi SY,Goldberg S

更新日期：2018-01-01 00:00:00

abstract：:A double-chambered right ventricle (DCRV) is an uncommon congenital anomaly: the right ventricle (RV) is divided into two chambers due to the presence of an abnormally located muscular band or anomalous muscle hypertrophy in the subinfundibular part of RV outflow tract, with a variable degree of obstruction. Generally...

journal_title：Cardiology

authors： Nikolic A,Jovovic L,Ilisic T,Antonic Z

更新日期：2016-01-01 00:00:00

abstract：:Patients with coronary artery disease can exhibit substantial vascular involvement; and vascular patients have a high incidence of coronary disease. Combined coronary artery bypass grafting (CABG) and treatment of extracranial cerebrovascular disease was performed in 52 patients, presenting strong indications for surg...

journal_title：Cardiology

authors： Carrel T,Stillhard G,Turina M

更新日期：1992-01-01 00:00:00

abstract：:Valsartan is a specific angiotensin II receptor antagonist with high selectivity for the AT(1) receptor subtype. After oral administration of single or repeated once-daily doses, valsartan 40-80 mg inhibits the pressor response to angiotensin II for 24 hours. In patients with mild-to-moderate hypertension, efficacy of...

journal_title：Cardiology

authors： McInnes GT

更新日期：1999-01-01 00:00:00

abstract：:Following electrocardiographic analysis, isolated or combined blocks in the intraventricular trifascicular system including predivisional left bundle branch block with left posterior hemiblock in Nigerians are presented and the underlying causes reviewed. The rarity of complete heart block, despite the not uncommon fa...

journal_title：Cardiology

authors： Cole TO,Falase AO

更新日期：1975-01-01 00:00:00

abstract：:The D1790G mutation was found in all 24 patients of an extended long QT family but not in 200 chromosomes carried by healthy individuals. We describe a 37-year-old man presenting with a typical spontaneous type 1 Brugada pattern who in electrophysiological testing had easily inducible ventricular fibrillation. At the ...

journal_title：Cardiology

authors： Blich M,Efrati E,Marai I,Suleiman M,Gepstein L,Boulous M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The systematic pro-inflammatory responses after percutaneous coronary intervention with drug-eluting stents (DES) remain poorly defined. Therefore, we compared the systematic pro-inflammatory state of circulating mononuclear cells (MNCs) between DES and bare metal stent (BMS) implantation. METHODS:Patients w...

journal_title：Cardiology

authors： Liu J,Zhuo XZ,Liu W,Wan Z,Wang X,Zhang W,Gao S,Yuan Z,Wu Y

更新日期：2014-01-01 00:00:00

abstract：:The efficacy of the transfemoral left-ventricular assist device Hemopump (HP; 21 Fr outer diameter) was examined in experiments with adult sheep in two different models of cardiogenic shock (tachycardia shock; ischemia shock), and during ventricular fibrillation. During tachycardia (high frequency pacing-induced; n = ...

journal_title：Cardiology

authors： Scholz KH,Hering JP,Schröder T,Uhlig P,Kreuzer H,Hellige G

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:Despite recent advances in cardiovascular surgery, hyperbilirubinemia after heart valve surgery occurs often and the mechanism is not well clarified. We evaluated the incidence and nature of postoperative hyperbilirubinemia in heart valve surgery patients to analyze its risk factors and to identify its clini...

journal_title：Cardiology

authors： Nishi H,Sakaguchi T,Miyagawa S,Yoshikawa Y,Fukushima S,Saito S,Ueno T,Kuratani T,Sawa Y

更新日期：2012-01-01 00:00:00

abstract：:Cardiovascular adaptation to the sudden inflation of a balloon in the descending aorta was investigated in intact awake, standing dogs. The balloon inflation raised pressure in the arterial bed proximal from the balloon. Initially, it lowered heart rate and cardiac output. After 4 sec, heart rate and cardiac output be...

journal_title：Cardiology

authors： Ehrlich W,Rodriguez-Lopez E

更新日期：1978-01-01 00:00:00

abstract：:The spectrum of patients operated on without preoperative catheterization and angiography, the accuracy of echocardiographic diagnosis and its impact on the results of surgical treatment were prospectively assessed in 2,788 children consecutively operated for congenital heart defects (CHD) between 1986 and 1992. The o...

journal_title：Cardiology

authors： Marek J,Skovránek J,Hucín B,Chaloupecký V,Tax P,Reich O,Samánek M

更新日期：1995-01-01 00:00:00

abstract：:Atrial fibrillation is a complex disease. Its etiologies are diverse and genetic factors may also contribute to this disease. With the advent of modern molecular biology technology, it is now possible to explore the genetic components in the pathogenesis of atrial fibrillation. Past molecular genetic studies on atrial...

journal_title：Cardiology

authors： Lai LP,Lin JL,Huang SK

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Currently, several modalities are available to predict viability, however, studies comparing various modalities validated by functional recovery after revascularization are scarce. This study analyzed the relative merits of low-dose dobutamine echocardiography, F-18 deoxyglucose (FDG) positron emission tomog...

journal_title：Cardiology

authors： Lund GK,Freyhoff J,Schwaiger M,Lübeck M,Lund CH,Buchert R,Sheehan FH,Meinertz T,Nienaber CA

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The shift toward a preventative approach in medical aftercare of congenital heart disease (CHD) patients has led to encouragement of regular physical activity (PA) in this patient population. Objective measures are crucial in accurately displaying PA levels and have increasingly found their way into clinical...

journal_title：Cardiology

authors： Brudy L,Meyer M,Garcia-Cuenllas L,Oberhoffer R,Hager A,Ewert P,Müller J

更新日期：2021-01-13 00:00:00

abstract：:An anonymous patient perception comprehension and satisfaction questionnaire was sent to 438 patients 1-3 months after they had participated in a clinical cardiovascular trial to examine the level of patient comprehension as perceived by the patient. We compared perceived comprehension in acute (acute myocardial infar...

journal_title：Cardiology

authors： Yuval R,Halon DA,Flugelman MY,Lewis BS

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were: (1) to evaluate the specificity of cardiac troponin I and creatine kinase-MB isoenzyme in ambulatory asymptomatic chronic renal failure patients on long-term hemodialysis, and (2) to evaluate the effect of hemodialysis on the serum levels of cardiac troponin I and creatine ...

journal_title：Cardiology

authors： Tun A,Khan IA,Win MT,Hussain A,Hla TA,Wattanasuwan N,Vasavada BC,Sacchi TJ

更新日期：1998-01-01 00:00:00