Perceived patient comprehension in acute and chronic cardiovascular clinical trials.

abstract：:At present nitrates remain the initial treatment for relief or prevention of angina in patients with coronary artery disease. In cases where nitrates and beta blockers have been used and are ineffective for managing effort angina, calcium antagonists may be substituted or added to the beta-blocking treatment. When the...

journal_title：Cardiology

authors： Conti CR,Pepine CJ,Feldman RL,Hill JA

更新日期：1985-01-01 00:00:00

abstract：:Three generations of a family with the Romano-Ward syndrome are described. Of all the affected members, only 1 was symptomatic, experiencing episodes of syncope proven to be due to polymorphous ventricular tachycardia (PMVT) induced by chlorimipramine treatment for depression. During treatment of an episode of PMVT wi...

journal_title：Cardiology

authors： Flugelman MY,Pollack S,Hammerman H,Riss E,Barzilai D

更新日期：1982-01-01 00:00:00

abstract：:Ibopamine is an active dopamine analogue leading to improved renal perfusion and afterload reduction in heart failure. This report describes casuistic experiences in patients with severe heart failure awaiting heart transplantation. All patients could be stabilized, intravenous catecholamines be discontinued, and diur...

journal_title：Cardiology

authors： Kleber FX,Sabin GV,Thyroff-Friesinger U,Cabell B,Glogar D

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To explore the role of platelet-derived growth factor-B (PDGF-B)/platelet-derived growth factor receptor-β (PDGFR-β) signaling in chronic atrial fibrillation (AF). METHODS:Thirty-nine AF patients and 33 patients with sinus rhythm (SR) were enrolled. Twenty canines were randomized into 5 groups: control, sham...

journal_title：Cardiology

authors： Jiang Z,Zhong G,Wen L,Hong Y,Fang S,Sun P,Li S,Li S,Feng G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The value of glycosylated hemoglobin (HbA1c) as a surrogate marker for the prevention of cardiovascular outcomes on antidiabetic drugs is debated. The 2008 FDA guidance led to multiple large clinical trials to evaluate the effect of new antidiabetic drugs versus placebo on major adverse cardia...

journal_title：Cardiology

authors： Ambrosi P,Daumas A,Villani P,Giorgi R

更新日期：2020-01-01 00:00:00

abstract：:The induction of spontaneous repetitive activity by a drive ('overdrive excitation') was studied in the sinoatrial node of the guinea pig by recording electrical and mechanical activity in sinoatrial preparations made quiescent by exposure to 20 mM caffeine of caffeine plus high [Ca]0. Electrical drive induced action ...

journal_title：Cardiology

authors： Vassalle M,Carbonin P,Iacono G,Di Gennaro M

更新日期：1988-01-01 00:00:00

abstract：:The D1790G mutation was found in all 24 patients of an extended long QT family but not in 200 chromosomes carried by healthy individuals. We describe a 37-year-old man presenting with a typical spontaneous type 1 Brugada pattern who in electrophysiological testing had easily inducible ventricular fibrillation. At the ...

journal_title：Cardiology

authors： Blich M,Efrati E,Marai I,Suleiman M,Gepstein L,Boulous M

更新日期：2015-01-01 00:00:00

abstract：:There has been recent interest in treating acute myocardial infarction with coronary reperfusion by fibrinolytic therapy. Experimental studies have shown that myocardial infarct size can be reduced by coronary reperfusion. However, return of cardiac function, high energy phosphate metabolism, and cardiac ultrastructur...

journal_title：Cardiology

authors： Kloner RA,Ellis SG,Carlson NV,Braunwald E

更新日期：1983-01-01 00:00:00

abstract：:The EKG response to exercise and the working capacity in a group of 70 patients with positive serology for Chagas' disease has been determined by stress testing on a bicycle-ergometer, in order to establish the usefulness of such a test in the early diagnosis of Chagas' cardiomyopathy. The exercise EKG provides inform...

journal_title：Cardiology

authors： Hirschhaut E,Aparicio JM

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that a lower lymphocyte ratio (Ly%) in the white blood cell (WBC) differential count is related to worse outcomes in patients with acute heart failure (AHF) and other cardiovascular disorders. METHODS:In the Pre-RELAX-AHF study, 234 patients with AHF, systolic blood pressure ...

journal_title：Cardiology

authors： Milo-Cotter O,Teerlink JR,Metra M,Felker GM,Ponikowski P,Voors AA,Edwards C,Weatherley BD,Greenberg B,Filippatos G,Unemori E,Teichman SL,Cotter G

更新日期：2010-01-01 00:00:00

abstract：:Hydrogenated oils containing trans-fatty acids (TFA) are used to produce margarine and various processed foods. TFA affect serum lipid levels, fatty acid metabolism, and endothelial function. High TFA intake is linked to increased all-cause mortality, coronary heart disease mortality, and cardiovascular disease (CVD) ...

journal_title：Cardiology

authors： Wilczek MM,Olszewski R,Krupienicz A

更新日期：2017-01-01 00:00:00

abstract：:Although very useful agents, fluoroquinolones are associated with a number of adverse events, some with considerable clinical significance. Prolongation of the QT interval, for example, is an adverse effect associated with the use of fluoroquinolones. Fluoroquinolones prolong the QT interval by blocking voltage-gated ...

journal_title：Cardiology

authors： Briasoulis A,Agarwal V,Pierce WJ

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the feasibility, reproducibility, safety and information obtained on exercise physiology from cardiopulmonary exercise testing (CPX) in patients with aortic stenosis. METHODS:Patients with an aortic valve area (AVA) <1.3 cm2 who were judged asymptomatic or equivocal sym...

journal_title：Cardiology

authors： van Le D,Jensen GV,Carstensen S,Kjøller-Hansen L

更新日期：2016-01-01 00:00:00

abstract：:Since recent studies demonstrated an impaired outcome after percutaneous coronary interventions (PCI) in patients with chronic renal failure but did not address the aetiology of renal failure, we now analysed the outcome of patients with diabetic nephropathy in 721 consecutive patients undergoing PCI. Diabetic nephrop...

journal_title：Cardiology

authors： Reinecke H,Matzkies F,Fobker M,Breithardt G,Schaefer RM

更新日期：2005-01-01 00:00:00

abstract：:Low cardiac output in acute heart failure can result in a functional impairment of organs, when tissue hypoxia occurs and cardiogenic shock develops. To restore cardiac output, various forms of therapy can be considered. Fluid replacement is sometimes beneficial in acute situations where oedema can reduce effective pl...

journal_title：Cardiology

authors： Vincent JL,Léon M,Berré J

更新日期：1990-01-01 00:00:00

abstract：:Nitrovasodilators relax vascular smooth muscle by stimulating soluble guanylate cyclase (GC). The resulting rise in cGMP probably initiates Ca extrusion from the smooth muscle cell which causes relaxation. Since repeated administration of organic nitrates, particularly nitroglycerin, leads to tolerance, i.e. a decreas...

journal_title：Cardiology

authors： Kukovetz WR,Holzmann S,Romanin C

更新日期：1987-01-01 00:00:00

abstract：:We performed this study in order to compare the immediate and mid-term outcomes of sirolimus-eluting stents (SES) and paclitaxel-eluting stents (PES) in lesions of the unprotected left main coronary artery (LMCA). We assessed 54 patients from 5 centers who had undergone unprotected LMCA stenting (35 SES and 19 PES). T...

journal_title：Cardiology

authors： Lee SH,Ko YG,Jang Y,Kwon HM,Lee SH,Yoon JH,Park SH,Kim BO,Jeon DW,Yang JY,Ryu SK,Korean Multicenter Angioplasty Team (KOMATE) Investigators.

更新日期：2005-01-01 00:00:00

abstract：:Carvedilol is a multiple-action cardiovascular agent that is a nonselective beta-adrenoceptor antagonist and a vasodilator. beta-Adrenoceptor antagonists reduce myocardial work, secondary to reductions in heart rate and contractility, both in animals and in humans. For these reasons, carvedilol may improve survival of...

journal_title：Cardiology

authors： Ruffolo RR Jr,Bril A,Feuerstein GZ

更新日期：1993-01-01 00:00:00

abstract：:Valsartan is a specific angiotensin II receptor antagonist with high selectivity for the AT(1) receptor subtype. After oral administration of single or repeated once-daily doses, valsartan 40-80 mg inhibits the pressor response to angiotensin II for 24 hours. In patients with mild-to-moderate hypertension, efficacy of...

journal_title：Cardiology

authors： McInnes GT

更新日期：1999-01-01 00:00:00

abstract：:The antiarrhythmic effects of tiapamil were investigated in 48 patients, mean age 54, with acute myocardial infarction and ventricular arrhythmias. 9 had ventricular tachycardia, 6 ventricular fibrillation, and 33 multifocal premature ventricular contractions. Before and after therapy, ECG parameters, left ventricular...

journal_title：Cardiology

authors： Lessem J

更新日期：1982-01-01 00:00:00

abstract：:Transcatheter electrical shock ablation of a concealed posteroseptal accessory pathway was performed on a 57-year-old man with drug-refractory paroxysmal supraventricular tachycardia. A single 300-joules shock delivered at the ostium of the coronary sinus abolished conduction in the accessory pathway and resulted in l...

journal_title：Cardiology

authors： Belhassen B,Shapira I,Miller H,Geller E,Laniado S

更新日期：1988-01-01 00:00:00

abstract：PURPOSE:It was the purpose of this study to demonstrate the feasibility of performing coronary artery flow and coronary flow reserve (CFR) measurements in normal human volunteers using a magnetic resonance (MR) phase contrast technique. MATERIALS AND METHODS:Coronary flow rate, flow velocity, peak flow and CFR were de...

journal_title：Cardiology

authors： Grist TM,Polzin JA,Bianco JA,Foo TK,Bernstein MA,Mistretta CM

更新日期：1997-01-01 00:00:00

abstract：:The left ventricular function of 14 acromegalic patients was investigated using radionuclide ventriculography. After labeling the red blood cells with 750-1,000 MBq 99mTc-pertechnetate, ECG-triggered left anterior oblique images were recorded. Fourier analysis was then performed on the time-activity curve of the left ...

journal_title：Cardiology

authors： Erbas T,Erbas B,Usman A,Bekdik CF

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:To substitute the stroke volume index (SVi) with flow rate (FR) in the hemodynamic classification of severe aortic stenosis (AS) with preserved ejection fraction (EF), in order to evaluate its prognostic value. METHODS:A total of 529 patients (78.8 ± 9.8 years old, 44.1% males) with isolated severe AS (aort...

journal_title：Cardiology

authors： Alexandru D,Pollack S,Petillo F,Cao JJ,Barasch E

更新日期：2018-01-01 00:00:00

abstract：:We evaluated the efficacy and safety of daily administration of gallopamil 150 mg/day and its effects on myocardial perfusion in a medium-term, randomized, double-blind, cross-over, placebo-controlled trial. We studied 19 patients (17 males and 2 females; mean age 57 +/- 6.8 years) with stable effort angina, angiograp...

journal_title：Cardiology

authors： Acanfora D,Vitale DF,Rengo C,Iannuzzi GL,Furgi G,Picone C,Rossi M,Trojano L,Rengo F

更新日期：1997-07-01 00:00:00

abstract：:The subcutaneous implantable cardioverter defibrillator (S-ICD) registry included very few patients with a body mass index (BMI) greater than 40. We present a case of a 40-year-old male with a BMI of 44 and ejection fraction of 25% who underwent S-ICD implantation for primary prevention of sudden cardiac death in the ...

journal_title：Cardiology

authors： Levine JD,Ellins C,Winn N,Kim R,Hsu SS,Catanzaro JN

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) is a well-recognized risk factor for heart failure (HF). We hypothesized that HF also increases the risk for DM. OBJECTIVE:We explored the hypothesis that HF is a risk factor for DM. METHODS:The Cardiovascular Health Study was a prospective cohort study of cardiovascular risk in ambu...

journal_title：Cardiology

authors： Guglin M,Lynch K,Krischer J

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To assess the relationship between nonalcoholic fatty liver disease (NAFLD) and arterial stiffness in nondiabetic, nonhypertensive individuals with and without metabolic syndrome (MetS). METHODS:Hepatic ultrasound and brachial-ankle pulse wave velocity (baPWV) were investigated in 4,467 individuals. The sub...

journal_title：Cardiology

authors： Kim BJ,Kim NH,Kim BS,Kang JH

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Red blood cell microparticles (RBCm) have potential adverse vascular effects and they have been shown to be elevated in ST elevation myocardial infarction (STEMI). The purpose of this study is to investigate their relationship with biochemical infarct size. METHODS:RBCm were quantified with flow cytometry i...

journal_title：Cardiology

authors： Giannopoulos G,Vrachatis DA,Oudatzis G,Paterakis G,Angelidis C,Koutivas A,Sianos G,Cleman MW,Filippatos G,Lekakis J,Deftereos S

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To compare all-cause mortality in JUPITER with other statin trials at 21 months of follow-up. BACKGROUND:Outcome advantages including all-cause mortality reduction yielded from the JUPITER trial support aggressive use of rosuvastatin and, perhaps by extension, other statins for primary prevention. Despite en...

journal_title：Cardiology

authors： Serebruany VL

更新日期：2011-01-01 00:00:00