Abstract:
:At present nitrates remain the initial treatment for relief or prevention of angina in patients with coronary artery disease. In cases where nitrates and beta blockers have been used and are ineffective for managing effort angina, calcium antagonists may be substituted or added to the beta-blocking treatment. When the predominant symptom is rest angina, and there is evidence suggesting coronary artery spasm, nitrates and a calcium antagonist can be effective therapy. In patients with heart block, bradyarrhythmias, heart failure, or hypertension nifedipine may be the drug of choice. In contrast verapamil merits choice when supraventricular tachycardia is present. Diltiazem appears intermediate between nifedipine and verapamil and may be particularly useful when hypotension or other side effects must be avoided.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Conti CR,Pepine CJ,Feldman RL,Hill JAdoi
10.1159/000173886subject
Has Abstractpub_date
1985-01-01 00:00:00pages
297-321issue
5-6eissn
0008-6312issn
1421-9751journal_volume
72pub_type
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