Abstract:
:Three generations of a family with the Romano-Ward syndrome are described. Of all the affected members, only 1 was symptomatic, experiencing episodes of syncope proven to be due to polymorphous ventricular tachycardia (PMVT) induced by chlorimipramine treatment for depression. During treatment of an episode of PMVT with lidocaine, the patient developed the 'torsade de pointes' variant of ventricular tachycardia, which progressed to ventricular fibrillation and was successfully treated with electroversion. The hazards of treating these patients with commonly used drugs, the possible etiologies for the Romano-Ward syndrome and its mode of inheritance are discussed.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Flugelman MY,Pollack S,Hammerman H,Riss E,Barzilai Ddoi
10.1159/000173500subject
Has Abstractpub_date
1982-01-01 00:00:00pages
170-4issue
3eissn
0008-6312issn
1421-9751journal_volume
69pub_type
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