Abstract:
:A 21-year-old woman with hypertension confirmed on ambulatory blood pressure monitoring and unresponsive to beta-blockers, diltiazem and amiloride was found to have serum potassium, renin and aldosterone levels at or just below the lower end of normal. Urinary glucocorticoid metabolite analysis revealed high excretion of cortisol and androgen metabolites, with normal serum cortisol levels. This pattern suggests a partial glucocorticoid resistance syndrome; such patients are more responsive to ACE inhibitors and spironolactone.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Shamim W,Bakhai A,Yousufuddin M,Coats AJdoi
10.1159/000007015subject
Has Abstractpub_date
2000-01-01 00:00:00pages
131-2issue
1-2eissn
0008-6312issn
1421-9751pii
7015journal_volume
93pub_type
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