Abstract:
:In this first clinical report of an idiopathic familial persistently short QT interval (QTI), we describe three members of one family (a 17-year-old female, her 21-year-old brother, and their 51-year-old mother) demonstrating this ECG phenomenon, associated in the 17-year-old with several episodes of paroxysmal atrial fibrillation requiring electrical cardioversion. Similar ECG changes seen in an unrelated 37-year-old patient were associated with sudden cardiac death. Our report also describes other manifestations of abnormal shortening of the QTI and considers the possible arrhythmogenic potential of the short QTI.
journal_name
Cardiologyjournal_title
Cardiologyauthors
Gussak I,Brugada P,Brugada J,Wright RS,Kopecky SL,Chaitman BR,Bjerregaard Pdoi
10.1159/000047299subject
Has Abstractpub_date
2000-01-01 00:00:00pages
99-102issue
2eissn
0008-6312issn
1421-9751pii
47299journal_volume
94pub_type
杂志文章相关文献
CARDIOLOGY文献大全abstract::Mass screening for heart disease in children can be accomplished by automatic analysis of phonocardiograms (PCG) obtained from five routine auscultation points. An ECG signal serves as reference. PCG signals exceeding 20% of the amplitude of the first heart sound S1 in the diastolic interval and 40% of S1 in the systo...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000169876
更新日期:1978-01-01 00:00:00
abstract:OBJECTIVES:To explore the relation between the baseline aortic valve gradient (AVG) as a continuous variable and clinical outcomes following transcatheter aortic valve implantation (TAVI) in general and specifically in patients with high-gradient aortic stenosis (AS). METHODS:We reviewed 317 consecutive patients who u...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000444007
更新日期:2016-01-01 00:00:00
abstract::The spectrum of patients operated on without preoperative catheterization and angiography, the accuracy of echocardiographic diagnosis and its impact on the results of surgical treatment were prospectively assessed in 2,788 children consecutively operated for congenital heart defects (CHD) between 1986 and 1992. The o...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176928
更新日期:1995-01-01 00:00:00
abstract:AIM:To determine the frequency and outcomes of coronary artery bypass graft (CABG) surgery in patients with a wide spectrum of acute coronary syndromes (ACS). METHODS AND RESULTS:We prospectively enrolled 10,484 ACS patients from 103 hospitals in 25 countries across Europe and the Mediterranean basin. Of the 10,204 pa...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1159/000081851
更新日期:2005-01-01 00:00:00
abstract::The early administration of nitrates in acute myocardial infarction (AMI) may lower myocardial oxygen demand and increase blood supply to the ischemic myocardium. Actually, nitrates are the drugs most largely used in AMI patients, but no definite proof of their clinical benefits had been reported before GISSI 3 and IS...
journal_title:Cardiology
pub_type: 杂志文章,meta分析
doi:10.1159/000176441
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Heart failure (HF) patients with diabetes mellitus experience poor prognosis. We assessed the independent predictive effect of prevalent diabetes mellitus on all-cause mortality in HF outpatients. Furthermore, we investigated if optimized HF medication differed in diabetic versus nondiabetic patients. METHO...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000444658
更新日期:2016-01-01 00:00:00
abstract::Clopidogrel, in combination with acetylsalicylic acid, has become a mainstay of the pharmacological therapy for patients with acute coronary syndromes, especially in those undergoing percutaneous coronary interventions (PCI). While a series of studies has shown that pre-treatment with a loading dose of clopidogrel 300...
journal_title:Cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000096988
更新日期:2007-01-01 00:00:00
abstract::Aortic dissection is accompanied by fever in about one third of the patients. However, fever of unknown origin as the predominant manifestation of aortic dissection seems to be extremely rare. A review of the English literature revealed only 3 patients characterized by fever as the principal sign of aortic dissection....
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000174770
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Previous studies using transesophageal echocardiography (TEE) report an association of valvular heart disease (VHD) with cerebral infarcts and central neuropsychiatric systemic lupus erythematosus (NPSLE). However, TEE cannot be routinely used. AIM:To determine if VHD detected by transthoracic echocardiogra...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000099104
更新日期:2007-01-01 00:00:00
abstract::Ibopamine is an active dopamine analogue leading to improved renal perfusion and afterload reduction in heart failure. This report describes casuistic experiences in patients with severe heart failure awaiting heart transplantation. All patients could be stabilized, intravenous catecholamines be discontinued, and diur...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175786
更新日期:1992-01-01 00:00:00
abstract::Since the reported incidence of pericardial effusion following thrombolysis is highly variable, we have evaluated 80 consecutive patients with first acute myocardial infarction treated with streptokinase. Two-dimensional echocardiographic studies were performed on days 1, 2, 3, and 7, at 3 and 6 weeks, and 3, 6, and 1...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177417
更新日期:1997-11-01 00:00:00
abstract::To assess possible age-related differences in the time of occurrence (hour of the day, day of the week, month of the year) of cardiopulmonary collapses of presumed cardiac etiology, 3,305 out-of-hospital patients registered by the Belgian Cardiopulmonary-Cerebral Resuscitation Study Group between 1983 and 1990 were st...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000176873
更新日期:1995-01-01 00:00:00
abstract::Valsartan is a specific angiotensin II receptor antagonist with high selectivity for the AT(1) receptor subtype. After oral administration of single or repeated once-daily doses, valsartan 40-80 mg inhibits the pressor response to angiotensin II for 24 hours. In patients with mild-to-moderate hypertension, efficacy of...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000047283
更新日期:1999-01-01 00:00:00
abstract::We investigated the incidence and determinants of early and late repeat hospitalization for cardiac causes in 378 patients following myocardial revascularization [199 coronary balloon angioplasty (PTCA), 179 coronary bypass surgery (CABG)] in a single cardiovascular center and followed for a median period of 13 years....
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000064681
更新日期:2002-01-01 00:00:00
abstract::An abundance of clinical trial data indicates that lipid-regulating therapy reduces coronary artery disease morbidity and mortality. In patients with established coronary artery disease, lipid regulation has been shown to attenuate progression of atherosclerosis and extend survival. In primary prevention, a clear bene...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000177138
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:Atrial fibrosis plays a critical role in atrial fibrillation (AF). A key event in the pathogenesis of fibrosis is the activation of fibroblasts (FBs) into myofibroblasts (MFBs). Paracrine factors released from MFBs lead to ion channel expression changes in cardiomyocytes (CMs). Downregulation of L-type calciu...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000505641
更新日期:2020-01-01 00:00:00
abstract::Lymphocytes can be activated to produce and release opioid peptides. We investigated the levels of immunoreactive beta-endorphin in peripheral blood mononuclear cells from 11 patients with acute myocardial infarction. The concentrations of beta-endorphin in mononuclear leukocytes of 30.2 +/- 6.9 pg/10(6) cells on admi...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000006815
更新日期:1998-07-01 00:00:00
abstract::We report the case of a man whose high-density lipoprotein cholesterol (HDL-C) and the ratios of total cholesterol to HDL-C and low-density lipoprotein cholesterol to HDL-C worsened dramatically during pravastatin treatment. After 3 years, pravastatin was replaced by fenofibrate. The result was spectacular. The HDL-C ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000063114
更新日期:2002-01-01 00:00:00
abstract::Hydrogenated oils containing trans-fatty acids (TFA) are used to produce margarine and various processed foods. TFA affect serum lipid levels, fatty acid metabolism, and endothelial function. High TFA intake is linked to increased all-cause mortality, coronary heart disease mortality, and cardiovascular disease (CVD) ...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000479956
更新日期:2017-01-01 00:00:00
abstract::To study the effects of steroid elution on chronic pacing threshold and impedance, a 4-mm2 surface area lead with steroid (030-368, Telectronics; n = 9) was compared to the same lead without steroid (030-359, Telectronics; n = 9) 3 months after implantation. The pulse duration thresholds of the steroid lead were signi...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000175976
更新日期:1993-01-01 00:00:00
abstract::This study shows significant changes occurring in systolic time intervals in an experimental animal model of aortic outflow obstruction with cardiac hypertrophy. The left ventricular ejection time is markedly prolonged and the preejection period/left ventricular ejection time ratio shortened. These changes are in the ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000173260
更新日期:1981-01-01 00:00:00
abstract::Single photon emission computed tomographic (SPECT) imaging with thallium-201 was evaluated in 492 consecutive, unselected patients to ascertain the patterns of use and additive value to the exercise electrocardiogram in the diagnosis of myocardial ischemia in a community hospital setting. Myocardial perfusion images ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177076
更新日期:1996-03-01 00:00:00
abstract::Calculated values of oxygen consumption have been used to calculate a Fick cardiac output when thermodilution measurements are unreliable and when oxygen consumption measurements are unavailable. To determine the accuracy of these calculations, we measured cardiac output in 20 patients by four methods: (1) a reference...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177304
更新日期:1997-01-01 00:00:00
abstract::This study was designed to assess the contribution of clinical, electrocardiographic and exercise hemodynamic variables to the prediction of normalization on resting reinjection scintigraphy of persistent thallium-201 (201Tl) myocardial perfusion defects seen with exercise and 2- to 4-hour delayed (redistribution) ima...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000177093
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVES:We tested the acute effects of resynchronization in heart failure patients with a normal (>50%) left ventricular (LV) ejection fraction (HFNEF) and mechanical dyssynchrony. METHODS:Twenty-four HFNEF patients (72 ± 6 years, 5 male) with mechanical dyssynchrony (standard deviation of electromechanical time de...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000368795
更新日期:2015-01-01 00:00:00
abstract::Pulmonary alveolar microlithiasis (PAM) is a rare disorder of uncertain etiology and pathogenesis that is characterized by tiny calcium phosphate depositions in lung alveoli. Ectopic organ involvement has been reported infrequently. We hereby present a patient with PAM complicated by severe pleural calcification that ...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000095420
更新日期:2007-01-01 00:00:00
abstract::Heart failure with a preserved ejection fraction (HFpEF) is increasingly prevalent and a leading cause of morbidity and mortality worldwide. HFpEF has a complex pathophysiology, with recent evidence suggesting that an interaction of cardiovascular and noncardiovascular comorbidities (e.g. obesity, hypertension, diabet...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000450573
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:A number of innovative approaches have been investigated for their value in the early detection of acute ischemia or infarction in patients presenting to the emergency department (ED) with chest pain suggestive of a cardiac origin. Prior investigations have demonstrated the utility of adding right precordial...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000077912
更新日期:2004-01-01 00:00:00
abstract::Renin is a key component of the renin-angiotensin system (RAS), which plays an important role in the maintenance of blood pressure and electrolyte-volume homeostasis. RAS also plays a role in cardiovascular (CV) disease as a result of effects on inflammation and oxidative stress. There is growing evidence that plasma ...
journal_title:Cardiology
pub_type: 杂志文章,评审
doi:10.1159/000348365
更新日期:2013-01-01 00:00:00
abstract:UNLABELLED:The risk for cardiovascular events conferred by decreased renal function is curvilinear with exponentially greater increases in risk as estimated glomerular filtration rate (eGFR) declines. In 13 non-diabetic pre-dialysis chronic kidney disease (CKD) patients, we employed quantitative F-18 fluorodeoxyglucose...
journal_title:Cardiology
pub_type: 杂志文章
doi:10.1159/000318227
更新日期:2010-01-01 00:00:00