解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:Purpose:Comorbidity indices are often used to measure comorbidities in register-based research. We aimed to adapt the Charlson comorbidity index (CCI) to a Swedish setting. Methods:Four versions of the CCI were compared and evaluated by disease-specific experts. Results:We created a cohesive coding system for CCI to ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S282475
更新日期:2021-01-12 00:00:00
abstract:Aim:To improve consistency between register studies in Sweden and ensure valid comparisons of possible changes in alcohol-related disorders and diseases (ARDDs) over time, we propose a definition of ARDDs. Based on this definition, we examined Sweden's incidence rates of ARDDs from 1970 to 2018 in non-primary healthcar...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S285936
更新日期:2020-12-31 00:00:00
abstract:Purpose:Obesity is an established risk factor for venous thromboembolism (VTE), while studies on physical inactivity and VTE risk show conflicting results. We examined whether physical activity modified the association between obesity and VTE. Patients and Methods:We conducted a population-based cohort study by combin...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S275079
更新日期:2020-12-08 00:00:00
abstract:Purpose:To establish the validity of intracerebral hemorrhage (ICH) diagnoses in the Danish Stroke Registry (DSR) and the Danish National Patient Registry (DNPR). Patients and Methods:Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S267583
更新日期:2020-12-01 00:00:00
abstract:Objective:To evaluate the long-term risk of stroke and poststroke adverse outcomes in patients with heart failure (HF). Methods:We used research data from Taiwan's National Health Insurance Program from 2000 to 2005 and identified 20,072 adults aged ≥30 years who were newly diagnosed with HF. Frequency matching based ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S261179
更新日期:2020-11-05 00:00:00
abstract::When healthcare professionals have the choice between several drug treatments for their patients, they often experience considerable decision uncertainty because many decisions simply have no single "best" choice. The challenges are manifold and include that guideline recommendations focus on randomized controlled tri...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S274466
更新日期:2020-11-02 00:00:00
abstract:Background:The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aim...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S265404
更新日期:2020-10-09 00:00:00
abstract:Purpose:Anemia is prevalent in patients with chronic kidney disease (CKD), but the longitudinal risk of anemia in patients with newly identified CKD is unknown. We therefore examined the risks of experiencing anemia in persons with newly identified CKD. Patients and Methods:This cohort study included adult patients wi...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S259648
更新日期:2020-09-11 00:00:00
abstract:Background:Sentinel lymph node biopsy (SLNB) was introduced over 30 years ago, but the application of SLNB in China is unclear. This study aimed to explore the real-world implementation of SLNB among early-stage breast cancer patients in China. Methods:A multi-center, retrospective study was conducted among primary br...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S264349
更新日期:2020-09-01 00:00:00
abstract:Purpose:To develop a self-administered diagnostic screening questionnaire for lumbar spinal stenosis (LSS) consisting of items with high content validity and to investigate the diagnostic value of the questionnaire and the items. Patients and Methods:A self-reported diagnostic LSS screening questionnaire was developed...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S263646
更新日期:2020-08-19 00:00:00
abstract:Purpose:To report completeness of registered surgeries in the Danish hip arthroscopy registry (DHAR) and proportion of patients completing patient-reported outcome measures (PROMs) prior to surgery and at 1-year follow-up. Patients and Methods:Completeness was determined as the number of surgeries registered in DHAR i...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S264683
更新日期:2020-08-04 00:00:00
abstract:Background:Prenatal exposures may contribute to male infertility in adult life, but large-scale epidemiological evidence is still lacking. The Fetal Programming of Semen quality (FEPOS) cohort was founded to provide means to examine if fetal exposures can interfere with fetal reproductive development and ultimately lea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S242631
更新日期:2020-07-17 00:00:00
abstract:Purpose:Inherited ichthyosis is a monogenetic disease characterized by hyperkeratosis and scaling of the skin, with large interindividual variation in severity. It can affect quality of life for patients and their families. Population-based data on inherited ichthyosis are lacking, which hampers studies into its epidem...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S232956
更新日期:2020-06-19 00:00:00
abstract:Background:Congenital red blood cell (RBC) disorders, such as hemoglobinopathies, are frequent worldwide but with large geographical variation. Growing migration has increased the number of patients with RBC disorders in formerly low prevalence countries, eg, Denmark. However, accurate prevalences are unknown. Methods...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S250251
更新日期:2020-05-21 00:00:00
abstract::[This corrects the article DOI: 10.2147/CLEP.S249903.]. ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,已发布勘误
doi:10.2147/CLEP.S259005
更新日期:2020-04-29 00:00:00
abstract:Purpose:Former studies have suggested that women with Crohn's disease (CD) and ulcerative colitis (UC) have a decreased chance of a live born child after assisted reproductive technology (ART) treatment. It is debated whether corticosteroids before ART may improve outcomes, either by decreasing inflammatory bowel disea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S234996
更新日期:2020-03-23 00:00:00
abstract:Purpose:To validate the use of International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) codes to identify patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in the Taiwan National Health Insurance (NHI) Outpatient Claims Dataset. Methods:We conducted ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S236823
更新日期:2020-02-20 00:00:00
abstract:Background:Cost-effective primary prevention of cardiovascular disease (CVD) relies on accuracy of risk assessment. Current risk scores require clinical and laboratory measures, are expensive and are often difficult to apply in the population setting. Objective:This study sought to estimate CVD risk from individuals' ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S219708
更新日期:2020-01-14 00:00:00
abstract:Objective:Reports on the epidemiology of vestibular schwannoma (VS) indicate an increase in diagnosed cases, often based on selected materials over a limited period of time. This report presents prospective 40-year epidemiological data from an unselected national cohort of all patients diagnosed with a VS in Denmark si...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S218670
更新日期:2019-11-08 00:00:00
abstract:Background:The combination of organized cervical cancer screening and childhood HPV vaccination programs has the potential to eliminate cervical cancer in the future. However, only women participating in both programs gain the full protection, and combined non-attenders remain at high risk of developing cervical cancer...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S203023
更新日期:2019-11-08 00:00:00
abstract:Purpose:Apolipoproteins C-I, C-II, C-III and E have been associated with risk of arterial thrombotic diseases. We investigated whether these apolipoproteins have prothrombotic properties and are associated with risk of venous thromboembolism (VTE). Patients and methods:A total of 127 VTE patients and 299 controls were...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S196266
更新日期:2019-07-22 00:00:00
abstract::Background: The Swedish National Patient Registry (NPR) is a nationwide registry that is used extensively for epidemiological research. Using the NPR, we recently found a recurrent pregnancy loss (RPL) incidence of 650/100,000 (0.65%) pregnant women in Sweden. It is of great importance that the quality of the coding i...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S199206
更新日期:2019-05-08 00:00:00
abstract::Introduction: Spontaneous (non-traumatic) subarachnoid hemorrhage (ntSAH) is frequently suspected in the emergency department, but the incidence rate is low. Diagnosis registers can provide valuable data for research in uncommon conditions like ntSAH. Unfortunately, validity vary in the registers. We aimed to assess t...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S197251
更新日期:2019-05-01 00:00:00
abstract:Objective:To determine the association of individual antidepressants (ADs) with the risk of traumatic brain injury (TBI) in the elderly. Patients and methods:We conducted a case-control study nested in a cohort of new users of ADs aged ≥65 years, identified in the German Pharmacoepidemiological Research Database durin...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S173667
更新日期:2019-02-15 00:00:00
abstract:Background:Previous studies have shown a link between increased dietary intake of arachidonic acid (ARA) and colorectal neoplasms. It has been shown that erythrocyte phospholipid membrane concentrations of ARA are strongly determined by genetic variation. Fatty acid desaturase (FADS) controls the rate limiting step in ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S186883
更新日期:2018-12-18 00:00:00
abstract:Purpose:Sharing of detailed individual-level data continues to pose challenges in multi-center studies. This issue can be addressed in part by using analytic methods that require only summary-level information to perform the desired multivariable-adjusted analysis. We examined the feasibility and empirical validity of ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S178163
更新日期:2018-11-27 00:00:00
abstract:Purpose:Synthetic oxytocin for labor augmentation during birth has been linked to negative neurodevelopment effects in children. We examined whether maternal labor augmentation was associated with lower cognitive ability in young adulthoods. Patients and methods:We identified 330,107 individuals (96.6% were men), with...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S181012
更新日期:2018-11-26 00:00:00
abstract:Background and aims:Canada's large geographic area and low population density pose challenges in access to specialized health care for remote and rural residents. We compared health services use, surgical rate, and specialist gastroenterologist care in rural and urban inflammatory bowel disease (IBD) patients in Canada...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S178056
更新日期:2018-11-08 00:00:00
abstract:Purpose:This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. Materials and methods:We investigated two primary care records databases covering UK National Health Service (Clinical Practice Resear...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164112
更新日期:2018-10-09 00:00:00
abstract:Objective:Maternal thyroid disease (TD) during pregnancy is associated with adverse birth outcomes, but little is known on its long-term outcomes. We aimed to examine if children born to mothers with TD have increased disease risk during childhood and adolescence. Patients and methods:A register-based cohort study was...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S167128
更新日期:2018-09-28 00:00:00
abstract:Background:Primary care databases represent a rich source of data for health care research; however, the quality of recording of secondary care events in these databases is uncertain. This study sought to investigate the completeness of recording of hospital admissions for bleeds in primary care records and explore the...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S170304
更新日期:2018-09-04 00:00:00
abstract:Background:Participation in cervical cancer screening varies by socioeconomic status. The aims were to assess if offering human papilloma virus (HPV) self-sampling kits has an effect on screening participation among various socioeconomic groups and to determine if two invitation strategies for offering self-sampling in...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164826
更新日期:2018-08-23 00:00:00
abstract:Aim:The EPICHRONIC (EPIdemiology of CHRONIC diseases) project investigated the possibility of developing common procedures for French and Spanish electronic health care databases to enable large-scale pharmacoepidemiological studies on chronic diseases. A feasibility study assessed the prevalence of type 2 diabetes mel...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S151890
更新日期:2018-07-27 00:00:00
abstract:Background:Decision makers in health care increasingly rely on nonrandomized database analyses to assess the effectiveness, safety, and value of medical products. Health care data scientists use data-adaptive approaches that automatically optimize confounding control to study causal treatment effects. This article summ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S166545
更新日期:2018-07-06 00:00:00
abstract:Background:Association between psoriasis severity and cerebro- and cardiovascular comorbidities has rarely been investigated. Aim:We aimed to investigate differences in cerebro- and cardiovascular comorbidities by psoriasis severity. Materials and methods:Using Swedish nationwide health-care registers, new adult user...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164918
更新日期:2018-06-19 00:00:00
abstract:Background:Individuals with a family history of Parkinson's disease (PD) appear to have a higher risk of developing PD and other neuropsychiatric diseases. However, estimates of the relative risks (RRs) of PD and the roles of genetic and environmental factors in PD susceptibility are unclear. The aim of this study was ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164330
更新日期:2018-05-30 00:00:00
abstract:Purpose:Substantial heterogeneity exists in reported kidney function decline in pre-dialysis chronic kidney disease (CKD). By design, kidney function decline can be studied in CKD 3-5 cohorts or dialysis-based studies. In the latter, patients are selected based on the fact that they initiated dialysis, possibly leading...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S153367
更新日期:2018-05-25 00:00:00
abstract::Characterizing the relations between exposures and diseases is the central tenet of epidemiology. Researchers may want to evaluate exposure-disease causation by assessing whether the disease under concern is induced by the various exposures - the so-called "attribution". In this paper, the authors propose a method to ...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S160205
更新日期:2018-04-27 00:00:00
abstract:Objective:To investigate the impact of moderate wine consumption on the risk of prostate cancer (PCa). We focused on the differential effect of moderate consumption of red versus white wine. Design:This study was a meta-analysis that includes data from case-control and cohort studies. Materials and methods:A systemat...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S163668
更新日期:2018-04-17 00:00:00
abstract:Background:In 2012, liver cancer ranked as the fifth and eighth most common cancer in men and women, respectively, in urban Shanghai. This study aims to present the trend and projection of age-specific incidence and mortality of liver cancer in Shanghai. Methods:We extracted data of liver cancer incident cases and dea...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S153951
更新日期:2018-03-09 00:00:00