Corticosteroids Prior to Embryo Transfer in Assisted Reproduction in Women with Crohn's Disease and Ulcerative Colitis - A Nationwide Cohort Study.

Abstract:

Purpose:Former studies have suggested that women with Crohn's disease (CD) and ulcerative colitis (UC) have a decreased chance of a live born child after assisted reproductive technology (ART) treatment. It is debated whether corticosteroids before ART may improve outcomes, either by decreasing inflammatory bowel disease-related inflammation or increasing endometrial receptivity. We examined the efficacy of corticosteroids before embryo transfer in women with CD and UC. Patients and Methods:Our cohort study is based on nationwide Danish health registries, comprising women with CD and UC receiving an embryo transfer (1 January 2006 through 2017). Exposed cohorts constituted women with CD and UC who had received corticosteroids within three months before embryo transfer, and the unexposed cohorts women with CD and UC who did not receive corticosteroids. Our primary outcome was live birth. We controlled for multiple covariates in the analyses. Results:We examined 2408 embryo transfers. In patients with CD, 114 embryo transfers were preceded by a corticosteroid prescription, and 964 were not. The corresponding numbers in UC were 122 and 1208, respectively. The adjusted odds ratio (aOR) for live birth in women with CD receiving corticosteroids before embryo transfer, relative to women with CD not receiving corticosteroids, was 0.89 (95% CI 0.49-1.63). The corresponding aOR in UC was 0.98 (95% CI 0.55-1.74). Conclusion:Corticosteroids prior to ART in women with CD and UC did not increase the chance of a live born child. The exact impact of corticosteroids prior to embryo transfer in patients with CD and UC still remains to be determined.

journal_name

Clin Epidemiol

journal_title

Clinical epidemiology

authors

Nørgård BM,Larsen MD,Friedman S,Fedder J

doi

10.2147/CLEP.S234996

subject

Has Abstract

pub_date

2020-03-23 00:00:00

pages

317-326

issn

1179-1349

pii

234996

journal_volume

12

pub_type

杂志文章
  • National Database of Geriatrics.

    abstract:AIM OF DATABASE:The aim of the National Database of Geriatrics is to monitor the quality of interdisciplinary diagnostics and treatment of patients admitted to a geriatric hospital unit. STUDY POPULATION:The database population consists of patients who were admitted to a geriatric hospital unit. Geriatric patients can...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.2147/CLEP.S99473

    authors: Kannegaard PN,Vinding KL,Hare-Bruun H

    更新日期:2016-10-25 00:00:00

  • Under-recording of hospital bleeding events in UK primary care: a linked Clinical Practice Research Datalink and Hospital Episode Statistics study.

    abstract:Background:Primary care databases represent a rich source of data for health care research; however, the quality of recording of secondary care events in these databases is uncertain. This study sought to investigate the completeness of recording of hospital admissions for bleeds in primary care records and explore the...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S170304

    authors: McDonald L,Sammon CJ,Samnaliev M,Ramagopalan S

    更新日期:2018-09-04 00:00:00

  • A Novel Method for Quantifying Intestinal Inflammatory Burden in Inflammatory Bowel Disease Using Register Data.

    abstract:Background:The Swedish Quality Register for Inflammatory Bowel Disease (SWIBREG) contains clinical data for the study of inflammatory bowel disease (IBD). The Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) cohort was recently established for the study of gastrointestinal histopathology. We aim...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S265404

    authors: Axelrad JE,Sachs MC,Ludvigsson JF,Olén O,SWIBREG Study Group.

    更新日期:2020-10-09 00:00:00

  • The impact of comorbidity on cancer survival: a review.

    abstract:BACKGROUND:A number of studies have shown poorer survival among cancer patients with comorbidity. Several mechanisms may underlie this finding. In this review we summarize the current literature on the association between patient comorbidity and cancer prognosis. Prognostic factors examined include tumor biology, diagn...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.2147/CLEP.S47150

    authors: Søgaard M,Thomsen RW,Bossen KS,Sørensen HT,Nørgaard M

    更新日期:2013-11-01 00:00:00

  • HPV self-sampling in cervical cancer screening: the effect of different invitation strategies in various socioeconomic groups - a randomized controlled trial.

    abstract:Background:Participation in cervical cancer screening varies by socioeconomic status. The aims were to assess if offering human papilloma virus (HPV) self-sampling kits has an effect on screening participation among various socioeconomic groups and to determine if two invitation strategies for offering self-sampling in...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S164826

    authors: Tranberg M,Bech BH,Blaakær J,Jensen JS,Svanholm H,Andersen B

    更新日期:2018-08-23 00:00:00

  • A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents.

    abstract:OBJECTIVE:The Department of Hematology, Zealand University Hospital, Denmark, and the National Institute of Public Health, University of Southern Denmark, created the first nationwide, population-based, and the most comprehensive cross-sectional health-related quality of life (HRQoL) survey of patients with myeloprolif...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S117587

    authors: Brochmann N,Flachs EM,Christensen AI,Andersen CL,Juel K,Hasselbalch HC,Zwisler AD

    更新日期:2017-03-02 00:00:00

  • Quality assessment of observational studies in a drug-safety systematic review, comparison of two tools: the Newcastle-Ottawa Scale and the RTI item bank.

    abstract:BACKGROUND:The study objective was to compare the Newcastle-Ottawa Scale (NOS) and the RTI item bank (RTI-IB) and estimate interrater agreement using the RTI-IB within a systematic review on the cardiovascular safety of glucose-lowering drugs. METHODS:We tailored both tools and added four questions to the RTI-IB. Two ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S66677

    authors: Margulis AV,Pladevall M,Riera-Guardia N,Varas-Lorenzo C,Hazell L,Berkman ND,Viswanathan M,Perez-Gutthann S

    更新日期:2014-10-10 00:00:00

  • Estimation of Cardiovascular Risk from Self-Reported Knowledge of Risk Factors: Insights from the Minnesota Heart Survey.

    abstract:Background:Cost-effective primary prevention of cardiovascular disease (CVD) relies on accuracy of risk assessment. Current risk scores require clinical and laboratory measures, are expensive and are often difficult to apply in the population setting. Objective:This study sought to estimate CVD risk from individuals' ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S219708

    authors: Duval S,Van't Hof JR,Steffen LM,Luepker RV

    更新日期:2020-01-14 00:00:00

  • Physical Activity as an Effect Modifier of the Association Between Obesity and Venous Thromboembolism: A Danish Population-Based Cohort Study.

    abstract:Purpose:Obesity is an established risk factor for venous thromboembolism (VTE), while studies on physical inactivity and VTE risk show conflicting results. We examined whether physical activity modified the association between obesity and VTE. Patients and Methods:We conducted a population-based cohort study by combin...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S275079

    authors: Solli H,Olsen M,Larsen FB,Pedersen L,Schmidt M

    更新日期:2020-12-08 00:00:00

  • Gastroenteritis attributable to rotavirus in hospitalized Saudi Arabian children in the period 2007-2008.

    abstract:PURPOSE:Rotavirus (RV) is a leading cause of severe gastroenteritis (GE) in children across the world. As there is a lack of epidemiological data for RV gastroenteritis (RVGE) in Saudi Arabia, this hospital-based study was designed to estimate the disease burden of RVGE and assess the prevalent RV types in Saudi childr...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S69502

    authors: Khalil M,Azhar E,Kao M,Al-Kaiedi N,Alhani H,Al Olayan I,Pawinski R,Gopala K,Kandeil W,Anis S,Van Doorn LJ,DeAntonio R

    更新日期:2015-02-11 00:00:00

  • Concordance of metabolic enzyme genotypes assayed from paraffin-embedded, formalin-fixed breast tumors and normal lymphatic tissue.

    abstract:OBJECTIVES:Translational epidemiology studies often use archived tumor specimens to evaluate genetic hypotheses involving cancer outcomes. When the exposure of interest is a germline polymorphism, a key concern is whether the genotype assayed from tumor-derived DNA is representative of the germline. We evaluated the co...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S13811

    authors: Ahern TP,Christensen M,Cronin-Fenton DP,Lunetta KL,Rosenberg CL,Sørensen HT,Lash TL,Hamilton-Dutoit S

    更新日期:2010-10-22 00:00:00

  • Validity of the recorded codes of gonadotropin-releasing hormone agonist treatment and orchiectomies in the Danish National Patient Registry.

    abstract:PURPOSE:Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid. We therefore estimated the positive predictive value (PPV) and negative predictive value (...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S32313

    authors: Jespersen CG,Borre M,Nørgaard M

    更新日期:2012-01-01 00:00:00

  • Non-Adherence To Childhood HPV Vaccination Is Associated With Non-Participation In Cervical Cancer Screening - A Nationwide Danish Register-Based Cohort Study.

    abstract:Background:The combination of organized cervical cancer screening and childhood HPV vaccination programs has the potential to eliminate cervical cancer in the future. However, only women participating in both programs gain the full protection, and combined non-attenders remain at high risk of developing cervical cancer...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S203023

    authors: Badre-Esfahani S,Larsen MB,Seibæk L,Petersen LK,Blaakær J,Støvring H,Andersen B

    更新日期:2019-11-08 00:00:00

  • The impact of moderate wine consumption on the risk of developing prostate cancer.

    abstract:Objective:To investigate the impact of moderate wine consumption on the risk of prostate cancer (PCa). We focused on the differential effect of moderate consumption of red versus white wine. Design:This study was a meta-analysis that includes data from case-control and cohort studies. Materials and methods:A systemat...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.2147/CLEP.S163668

    authors: Vartolomei MD,Kimura S,Ferro M,Foerster B,Abufaraj M,Briganti A,Karakiewicz PI,Shariat SF

    更新日期:2018-04-17 00:00:00

  • Risk of Anemia in Patients with Newly Identified Chronic Kidney Disease - A Population-Based Cohort Study.

    abstract:Purpose:Anemia is prevalent in patients with chronic kidney disease (CKD), but the longitudinal risk of anemia in patients with newly identified CKD is unknown. We therefore examined the risks of experiencing anemia in persons with newly identified CKD. Patients and Methods:This cohort study included adult patients wi...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S259648

    authors: Vestergaard SV,Heide-Jørgensen U,van Haalen H,James G,Hedman K,Birn H,Thomsen RW,Christiansen CF

    更新日期:2020-09-11 00:00:00

  • Matched case-control studies: a review of reported statistical methodology.

    abstract:BACKGROUND:Case-control studies are a common and efficient means of studying rare diseases or illnesses with long latency periods. Matching of cases and controls is frequently employed to control the effects of known potential confounding variables. The analysis of matched data requires specific statistical methods. M...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S30816

    authors: Niven DJ,Berthiaume LR,Fick GH,Laupland KB

    更新日期:2012-01-01 00:00:00

  • Emergent trends in the reported incidence of prostate cancer in Nigeria.

    abstract:BACKGROUND:To date there has not been any nationwide age-standardized incidence data reported for prostate cancer in Nigeria. We examined and integrated diverse trends in the age-specific incidence of prostate cancer into a comprehensive trend for Nigeria, and examined how best the existing data could generate a countr...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S23536

    authors: Ifere GO,Abebe F,Ananaba GA

    更新日期:2012-01-01 00:00:00

  • Arachidonic acid and colorectal adenoma risk: a Mendelian randomization study.

    abstract:Background:Previous studies have shown a link between increased dietary intake of arachidonic acid (ARA) and colorectal neoplasms. It has been shown that erythrocyte phospholipid membrane concentrations of ARA are strongly determined by genetic variation. Fatty acid desaturase (FADS) controls the rate limiting step in ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S186883

    authors: Isom CA,Shrubsole MJ,Cai Q,Smalley WE,Ness RM,Zheng W,Murff HJ

    更新日期:2018-12-18 00:00:00

  • Clinical course of nonalcoholic fatty liver disease: an assessment of severity, progression, and outcomes.

    abstract:Purpose:To identify the characteristics and initial disease severity of patients with nonalcoholic fatty liver disease (NAFLD) and assess incidence and risk factors for disease progression in a retrospective study. Methods:Patients ≥18 years of age without alcoholism or other liver diseases (eg, hepatitis B/C) were se...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S144368

    authors: Simeone JC,Bae JP,Hoogwerf BJ,Li Q,Haupt A,Ali AK,Boardman MK,Nordstrom BL

    更新日期:2017-12-14 00:00:00

  • Comorbidity index in central cancer registries: the value of hospital discharge data.

    abstract:Background:The presence of comorbid medical conditions can significantly affect a cancer patient's treatment options, quality of life, and survival. However, these important data are often lacking from population-based cancer registries. Leveraging routine linkage to hospital discharge data, a comorbidity score was cal...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S146395

    authors: Lichtensztajn DY,Giddings BM,Morris CR,Parikh-Patel A,Kizer KW

    更新日期:2017-11-20 00:00:00

  • Incidence of ICD-Based Diagnoses of Alcohol-Related Disorders and Diseases from Swedish Nationwide Registers and Suggestions for Coding.

    abstract:Aim:To improve consistency between register studies in Sweden and ensure valid comparisons of possible changes in alcohol-related disorders and diseases (ARDDs) over time, we propose a definition of ARDDs. Based on this definition, we examined Sweden's incidence rates of ARDDs from 1970 to 2018 in non-primary healthcar...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S285936

    authors: Bergman D,Hagström H,Capusan AJ,Mårild K,Nyberg F,Sundquist K,Ludvigsson JF

    更新日期:2020-12-31 00:00:00

  • The optimal hormonal replacement modality selection for multiple organ procurement from brain-dead organ donors.

    abstract::The management of brain-dead organ donors is complex. The use of inotropic agents and replacement of depleted hormones (hormonal replacement therapy) is crucial for successful multiple organ procurement, yet the optimal hormonal replacement has not been identified, and the statistical adjustment to determine the best ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S71403

    authors: Mi Z,Novitzky D,Collins JF,Cooper DK

    更新日期:2014-12-22 00:00:00

  • Age-specific cancer survival in Estonia: recent trends and data quality.

    abstract:BACKGROUND:A number of population-based studies have demonstrated lower cancer survival in elderly patients than among middle-aged or younger patients. Also, data quality in cancer registries has been shown to be associated with age. The objective of this study was to examine the recent age-specific cancer survival tre...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S87699

    authors: Innos K,Lang K,Pärna K,Aareleid T

    更新日期:2015-07-29 00:00:00

  • Hypertrophic scarring in cleft lip repair: a comparison of incidence among ethnic groups.

    abstract:BACKGROUND:Although hypertrophic scar (HTS) formation following cleft lip repair is relatively common, published rates vary widely, from 1% to nearly 50%. The risk factors associated with HTS formation in cleft patients are not well characterized. The primary aim of this retrospective study of 180 cleft lip repairs is ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S31119

    authors: Soltani AM,Francis CS,Motamed A,Karatsonyi AL,Hammoudeh JA,Sanchez-Lara PA,Reinisch JF,Urata MM

    更新日期:2012-01-01 00:00:00

  • Reliability of recurrent pregnancy loss diagnosis coding in the Swedish National Patient Register: a validation study.

    abstract::Background: The Swedish National Patient Registry (NPR) is a nationwide registry that is used extensively for epidemiological research. Using the NPR, we recently found a recurrent pregnancy loss (RPL) incidence of 650/100,000 (0.65%) pregnant women in Sweden. It is of great importance that the quality of the coding i...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S199206

    authors: Rasmark Roepke E,Christiansen OB,Hansson SR

    更新日期:2019-05-08 00:00:00

  • Antidepressants and the risk of traumatic brain injury in the elderly: differences between individual agents.

    abstract:Objective:To determine the association of individual antidepressants (ADs) with the risk of traumatic brain injury (TBI) in the elderly. Patients and methods:We conducted a case-control study nested in a cohort of new users of ADs aged ≥65 years, identified in the German Pharmacoepidemiological Research Database durin...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S173667

    authors: Pisa FE,Reinold J,Kollhorst B,Haug U,Schink T

    更新日期:2019-02-15 00:00:00

  • The database of the Danish Renal Cancer Group.

    abstract:AIM OF THE DATABASE:The main purpose of the database of the Danish Renal Cancer Group (DaRenCaData) is to improve the quality of renal cancer treatment in Denmark and secondarily to conduct observational research. STUDY POPULATION:DaRenCaData includes all Danish patients with a first-time diagnosis of renal cancer in ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.2147/CLEP.S106042

    authors: Petersen AC,Søgaard M,Mehnert F,Larsen EH,Donskov F,Azawi NH,Kromann-Andersen B

    更新日期:2016-10-25 00:00:00

  • Familial aggregation of Parkinson's disease and coaggregation with neuropsychiatric diseases: a population-based cohort study.

    abstract:Background:Individuals with a family history of Parkinson's disease (PD) appear to have a higher risk of developing PD and other neuropsychiatric diseases. However, estimates of the relative risks (RRs) of PD and the roles of genetic and environmental factors in PD susceptibility are unclear. The aim of this study was ...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S164330

    authors: Liu FC,Lin HT,Kuo CF,Hsieh MY,See LC,Yu HP

    更新日期:2018-05-30 00:00:00

  • Diagnostic Screening for Lumbar Spinal Stenosis.

    abstract:Purpose:To develop a self-administered diagnostic screening questionnaire for lumbar spinal stenosis (LSS) consisting of items with high content validity and to investigate the diagnostic value of the questionnaire and the items. Patients and Methods:A self-reported diagnostic LSS screening questionnaire was developed...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S263646

    authors: Jensen RK,Lauridsen HH,Andresen ADK,Mieritz RM,Schiøttz-Christensen B,Vach W

    更新日期:2020-08-19 00:00:00

  • Rural and urban disparities in the care of Canadian patients with inflammatory bowel disease: a population-based study.

    abstract:Background and aims:Canada's large geographic area and low population density pose challenges in access to specialized health care for remote and rural residents. We compared health services use, surgical rate, and specialist gastroenterologist care in rural and urban inflammatory bowel disease (IBD) patients in Canada...

    journal_title:Clinical epidemiology

    pub_type: 杂志文章

    doi:10.2147/CLEP.S178056

    authors: Benchimol EI,Kuenzig ME,Bernstein CN,Nguyen GC,Guttmann A,Jones JL,Potter BK,Targownik LE,Catley CA,Nugent ZJ,Tanyingoh D,Mojaverian N,Underwood FE,Siddiq S,Otley AR,Bitton A,Carroll MW,deBruyn JC,Dummer TJ,El-Matar

    更新日期:2018-11-08 00:00:00