当前位置： SCI文献检索 > Clinical Epidemiology期刊下所有文献 > Diagnostic Screening for Lumbar Spinal Stenosis.

Diagnostic Screening for Lumbar Spinal Stenosis.

Abstract：

Purpose:To develop a self-administered diagnostic screening questionnaire for lumbar spinal stenosis (LSS) consisting of items with high content validity and to investigate the diagnostic value of the questionnaire and the items. Patients and Methods:A self-reported diagnostic LSS screening questionnaire was developed based on items from the existing literature describing key symptoms of LSS. The screening questionnaire (index test) was to be tested in a cohort of patients with persistent lumbar and/or leg pain recruited from a Danish publicly funded outpatient secondary care spine clinic with clinicians performing the reference test. However, to avoid unnecessary collection of data if the screening questionnaire proved to be of limited value, a case-control design was incorporated into the cohort design including an interim analysis. Additional cases for the case-control study were recruited at two Danish publicly funded spine surgery departments. Prevalence, sensitivity, specificity and diagnostic odds ratio (OR) were calculated for each individual item, and AUC (area under the curve) was calculated to examine the performance of the full questionnaire. Results:A 13-item Danish questionnaire was developed and tested in 153 cases and 230 controls. The interim analysis was not in favour of continuing the cohort study, and therefore, only results from the case-control study are reported. There was a positive association for all items except the presence of back pain. However, the association was only moderate with ORs up to 3.3. When testing the performance of the whole questionnaire, an AUC of 0.72 was reached with a specificity of 20% for a fixed sensitivity of 95%. Conclusion:The items were associated with LSS and therefore have some potential to identify LSS patients. However, the association was not strong enough to provide sufficient accuracy for a diagnostic tool. Additional dimensions of symptoms of LSS need identification to obtain a reliable questionnaire for screening purposes.

journal_name

Clin Epidemiol

journal_title

Clinical epidemiology

authors

Jensen RK,Lauridsen HH,Andresen ADK,Mieritz RM,Schiøttz-Christensen B,Vach W

doi

10.2147/CLEP.S263646

subject

Has Abstract

pub_date

2020-08-19 00:00:00

pages

891-905

issn

1179-1349

pii

263646

journal_volume

pub_type

杂志文章

在线工具

Diagnostic Screening for Lumbar Spinal Stenosis.