Abstract:
Purpose:To establish the validity of intracerebral hemorrhage (ICH) diagnoses in the Danish Stroke Registry (DSR) and the Danish National Patient Registry (DNPR). Patients and Methods:Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009-2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, without underlying structural cause). We also calculated the sensitivity of these diagnoses in each of the registers. Finally, we classified the location of verified s-ICH. Results:A total of 3,956 patients with ICH diagnosis codes were studied (DSR only: 87; DNPR only: 1,513; both registries: 2,356). In the DSR, the PPVs were 86.5% (95% CI=85.1-87.8) for a-ICH and 81.8% (95% CI=80.2-83.3) for s-ICH. The PPVs in DNPR (discharge code, primary diagnostic position) were 76.2% (95% CI=74.7-77.6) for a-ICH and 70.2% (95% CI=68.6-71.8) for s-ICH. Sensitivity for a-ICH and s-ICH was 76.4% (95% CI=74.8-78.0) and 78.7% (95% CI=77.1-80.2) in DSR, and 87.3% (95% CI=86.0-88.5) and 87.7% (95% CI=86.3-88.9) in DNPR. The location of verified s-ICH was lobar (39%), deep (33.6%), infratentorial (13.2%), large unclassifiable (11%), isolated intraventricular (1.9%), or unclassifiable due to insufficient information (1.3%). Conclusion:The validity of a-ICH diagnoses is high in both registries. For s-ICH, PPV was higher in DSR, while sensitivity was higher in DNPR. The location of s-ICH was similar to distributions seen in other populations.
journal_name
Clin Epidemioljournal_title
Clinical epidemiologyauthors
Hald SM,Kring Sloth C,Agger M,Schelde-Olesen MT,Højholt M,Hasle M,Bogetofte H,Olesrud I,Binzer S,Madsen C,Krone W,García Rodríguez LA,Al-Shahi Salman R,Hallas J,Gaist Ddoi
10.2147/CLEP.S267583subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1313-1325issn
1179-1349pii
267583journal_volume
12pub_type
杂志文章abstract:Aim:The EPICHRONIC (EPIdemiology of CHRONIC diseases) project investigated the possibility of developing common procedures for French and Spanish electronic health care databases to enable large-scale pharmacoepidemiological studies on chronic diseases. A feasibility study assessed the prevalence of type 2 diabetes mel...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S151890
更新日期:2018-07-27 00:00:00
abstract:PURPOSE:The primary objective of this study is to examine the race-specific associations between statin use and overall mortality, as well as cardiovascular and cancer mortality, among blacks and whites in the Southeastern United States (US). Little is known about these associations in blacks. PATIENTS AND METHODS:The...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S53492
更新日期:2013-12-19 00:00:00
abstract:BACKGROUND:Data on the safety of selective serotonin-reuptake inhibitors (SSRIs) in pregnancy are inconsistent. We examined associations between SSRI use during early pregnancy and risk of congenital malformations in infants. METHODS:Set in Northern Denmark, our population-based prevalence study included 216,042 women...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/clep.s9256
更新日期:2010-08-09 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. Since the global spread of MRSA in the 1960s, MRSA strains have evolved with increased pathogenic potential. Notably, some strains are now capable of causing persistent infections not only in...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S37071
更新日期:2013-07-04 00:00:00
abstract:PURPOSE:Large-scale observational studies based on existing medical databases may have an important role in studies of long-term effects of different treatments in prostate cancer patients if the coding of the treatment is valid. We therefore estimated the positive predictive value (PPV) and negative predictive value (...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S32313
更新日期:2012-01-01 00:00:00
abstract:Purpose:Substantial heterogeneity exists in reported kidney function decline in pre-dialysis chronic kidney disease (CKD). By design, kidney function decline can be studied in CKD 3-5 cohorts or dialysis-based studies. In the latter, patients are selected based on the fact that they initiated dialysis, possibly leading...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S153367
更新日期:2018-05-25 00:00:00
abstract:BACKGROUND:To date there has not been any nationwide age-standardized incidence data reported for prostate cancer in Nigeria. We examined and integrated diverse trends in the age-specific incidence of prostate cancer into a comprehensive trend for Nigeria, and examined how best the existing data could generate a countr...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S23536
更新日期:2012-01-01 00:00:00
abstract:Background:Participation in cervical cancer screening varies by socioeconomic status. The aims were to assess if offering human papilloma virus (HPV) self-sampling kits has an effect on screening participation among various socioeconomic groups and to determine if two invitation strategies for offering self-sampling in...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S164826
更新日期:2018-08-23 00:00:00
abstract:Background:Sentinel lymph node biopsy (SLNB) was introduced over 30 years ago, but the application of SLNB in China is unclear. This study aimed to explore the real-world implementation of SLNB among early-stage breast cancer patients in China. Methods:A multi-center, retrospective study was conducted among primary br...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S264349
更新日期:2020-09-01 00:00:00
abstract:Background and aims:Canada's large geographic area and low population density pose challenges in access to specialized health care for remote and rural residents. We compared health services use, surgical rate, and specialist gastroenterologist care in rural and urban inflammatory bowel disease (IBD) patients in Canada...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S178056
更新日期:2018-11-08 00:00:00
abstract:Purpose:To identify the characteristics and initial disease severity of patients with nonalcoholic fatty liver disease (NAFLD) and assess incidence and risk factors for disease progression in a retrospective study. Methods:Patients ≥18 years of age without alcoholism or other liver diseases (eg, hepatitis B/C) were se...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S144368
更新日期:2017-12-14 00:00:00
abstract:AIM OF DATABASE:The aim of the National Database of Geriatrics is to monitor the quality of interdisciplinary diagnostics and treatment of patients admitted to a geriatric hospital unit. STUDY POPULATION:The database population consists of patients who were admitted to a geriatric hospital unit. Geriatric patients can...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99473
更新日期:2016-10-25 00:00:00
abstract::Memory diseases are the most important determinant of health care service use and quality of life among older individuals. Adverse effects of medication are common among older people, but this age group is underrepresented in clinical trials. Finnish statutory health care and prescription registers, together with pers...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S46622
更新日期:2013-08-07 00:00:00
abstract:Objective:Reports on the epidemiology of vestibular schwannoma (VS) indicate an increase in diagnosed cases, often based on selected materials over a limited period of time. This report presents prospective 40-year epidemiological data from an unselected national cohort of all patients diagnosed with a VS in Denmark si...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S218670
更新日期:2019-11-08 00:00:00
abstract:BACKGROUND:Data from the Nordic health care registers have been of great value in perinatal epidemiological research. It has been assumed that findings from the Nordic population (Denmark, Finland, Iceland, Norway, and Sweden) are applicable to other populations as well, including the population of the US. OBJECTIVE:T...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S106126
更新日期:2016-08-03 00:00:00
abstract::When healthcare professionals have the choice between several drug treatments for their patients, they often experience considerable decision uncertainty because many decisions simply have no single "best" choice. The challenges are manifold and include that guideline recommendations focus on randomized controlled tri...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S274466
更新日期:2020-11-02 00:00:00
abstract::Sjögren's syndrome is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands. It can present as an entity by itself, primary Sjögren's syndrome (pSS), or in addition to another autoimmune disease, secondary Sjögren's syndrome (sSS). pSS has a strong female propensity and is ...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S47399
更新日期:2014-07-30 00:00:00
abstract:OBJECTIVE:Invasive bladder cancer (IBC) is a common urological malignancy accounting for 4%-5% of all cancers in Denmark. Our aim was to examine possible changes in short- and long-term survival of patients with IBC during 1998-2009. STUDY DESIGN AND SETTING:Data on all patients (N = 4032) with an incident diagnosis o...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S20615
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Primary hyperparathyroidism (pHPT) is associated with an increased risk of developing breast cancer, but little is known about the underlying factors. The aim of this study was to compare women with a history of pHPT and a reference population in terms of standard factors predictive of prognosis and response...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S17298
更新日期:2011-03-25 00:00:00
abstract::Long-term storage of biological samples from patients has become increasingly important in studies of disease control and treatment. The first nationwide Danish diabetes project, ie, The Danish Center for Strategic Research in Type II Diabetes (DD2), aims to improve treatment and the long-term outcome of patients with...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S33042
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Validation of definitions used to identify conditions of interest is imperative to epidemiologic studies based on routinely collected data. The objective of the study was thus to estimate positive predictive values (PPVs) of International Classification of Diseases, 10th Revision (ICD-10) codes to identify c...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S139895
更新日期:2017-08-17 00:00:00
abstract:Purpose:Synthetic oxytocin for labor augmentation during birth has been linked to negative neurodevelopment effects in children. We examined whether maternal labor augmentation was associated with lower cognitive ability in young adulthoods. Patients and methods:We identified 330,107 individuals (96.6% were men), with...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S181012
更新日期:2018-11-26 00:00:00
abstract:Purpose:To develop a self-administered diagnostic screening questionnaire for lumbar spinal stenosis (LSS) consisting of items with high content validity and to investigate the diagnostic value of the questionnaire and the items. Patients and Methods:A self-reported diagnostic LSS screening questionnaire was developed...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S263646
更新日期:2020-08-19 00:00:00
abstract:AIM:In 2008, the Danish National Chronic Lymphocytic Leukemia Registry was founded within the Danish National Hematology Database. The primary aim of the registry is to assure quality of diagnosis and care of patients with chronic lymphocytic leukemia (CLL) in Denmark. Secondarily, to evaluate adherence to national gui...
journal_title:Clinical epidemiology
pub_type: 杂志文章,评审
doi:10.2147/CLEP.S99486
更新日期:2016-10-25 00:00:00
abstract:INTRODUCTION:Smoking is a main risk factor for morbidity and mortality in people living with human immunodeficiency virus (PLHIV), but its potential association with renal impairment remains to be established. METHODS:We did a nationwide population-based cohort study in Danish PLHIV to evaluate the association between...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S83530
更新日期:2015-08-28 00:00:00
abstract:Aim:To improve consistency between register studies in Sweden and ensure valid comparisons of possible changes in alcohol-related disorders and diseases (ARDDs) over time, we propose a definition of ARDDs. Based on this definition, we examined Sweden's incidence rates of ARDDs from 1970 to 2018 in non-primary healthcar...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S285936
更新日期:2020-12-31 00:00:00
abstract::Routinely-collected health data (RCD) are now used for a wide range of studies, including observational studies, comparative effectiveness research, diagnostics, studies of adverse effects, and predictive analytics. At the same time, limitations inherent in using data collected without specific a priori research quest...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S110528
更新日期:2016-10-19 00:00:00
abstract:BACKGROUND:Physical activity (PA) and its relationship with all-cause mortality suggest a strong and consistent inverse association. This study prospectively investigated the association between PA level and mortality among participants of the Norwegian Women and Cancer (NOWAC) Study. METHODS:A total of 66,136 NOWAC p...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S22681
更新日期:2011-01-01 00:00:00
abstract:Purpose:To report completeness of registered surgeries in the Danish hip arthroscopy registry (DHAR) and proportion of patients completing patient-reported outcome measures (PROMs) prior to surgery and at 1-year follow-up. Patients and Methods:Completeness was determined as the number of surgeries registered in DHAR i...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S264683
更新日期:2020-08-04 00:00:00
abstract:BACKGROUND:With the emergence of new lipid-lowering therapies, more patients are expected to achieve substantial lowering of low-density lipoprotein cholesterol (LDL-C). However, there are limited data examining the clinical experience of patients with low (<1.3 mmol/L) or very low (<0.65 mmol/L) levels of LDL-C. To pr...
journal_title:Clinical epidemiology
pub_type: 杂志文章
doi:10.2147/CLEP.S77676
更新日期:2015-02-26 00:00:00