听力与言语-语言病理学

行为科学

医学伦理学

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  • Experimental increase of blood glucose alters resting state EEG measures of excitation-inhibition balance.

    abstract:NEW FINDINGS:What is the central question of this study? Glucose is the dominant energy source for the brain. However, little is known about how glucose metabolism impacts the coordination of network activity in the brain in healthy adults. What is the main finding and its importance? We demonstrate that both alpha osc...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP089211

    authors: Walker CP,Buse J,Frohlich F

    更新日期:2021-01-28 00:00:00

  • Changes in prefrontal cerebral oxygenation and microvascular blood volume in hypoxia and possible association with acute mountain sickness.

    abstract:NEW FINDINGS:What is the central question of this study? The role of the cerebral haemodynamic response to either normobaric or hypobaric hypoxia in people susceptible to acute mountain sickness (AMS) is still under debate. Prefrontal cortex near-infrared spectroscopy-derived parameters were monitored in normobaric hyp...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088515

    authors: Manferdelli G,Marzorati M,Easton C,Porcelli S

    更新日期:2021-01-01 00:00:00

  • Combined methazolamide and theophylline improves oxygen saturation but not exercise performance or altitude illness in acute hypobaric hypoxia.

    abstract:NEW FINDINGS:What is the central question of this study? Does the combination of methazolamide and theophylline reduce symptoms of acute mountain sickness (AMS) and improve aerobic performance in acute hypobaric hypoxia? What is the main finding and its importance? The oral combination of methazolamide (100 BID) and th...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088461

    authors: Subudhi AW,Evero O,Reitinger J,Davis C,Gronewold J,Nichols AJ,Van-Houten SJ,Roach RC

    更新日期:2021-01-01 00:00:00

  • Cerebral haemodynamics and oxygenation during whole-body exercise over 5 days at high altitude.

    abstract:NEW FINDINGS:What is the central question of this study? Impairment and subsequent improvement in cerebral oxygenation during acute and prolonged exposure to high altitude affect exercise performance. This study innovates by investigating the effect of acute and prolonged high-altitude exposure on cerebral haemodynamic...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088354

    authors: Marillier M,Rupp T,Bouzat P,Walther G,Baillieul S,Millet GY,Robach P,Verges S

    更新日期:2021-01-01 00:00:00

  • Acute phase response to exertional heat stroke in mice.

    abstract:NEW FINDINGS:What is the central question of this study? Exertional heat stroke is accompanied by a marked inflammatory response. In this study, we explored the time course of acute phase proteins during recovery from severe heat stress in mice and the potential role of skeletal muscles as their source. What is the mai...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088501

    authors: Iwaniec J,Robinson GP,Garcia CK,Murray KO,de Carvalho L,Clanton TL,Laitano O

    更新日期:2021-01-01 00:00:00

  • Previous recreational cold exposure does not alter endothelial function or sensory thermal thresholds in the hands or feet.

    abstract:NEW FINDINGS:What is the central question of this study? Does recreational cold exposure result in cold sensitivity and is this associated with endothelial dysfunction and impaired sensory thermal thresholds? What is the main finding and its importance? Previous cold exposure was correlated with cold sensitivity of the...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088555

    authors: Eglin CM,Costello JT,Tipton MJ,Massey H

    更新日期:2021-01-01 00:00:00

  • Homeobox A5 and C10 genes modulate adaptation of brown adipose tissue during exercise training in juvenile rats.

    abstract:NEW FINDINGS:What is the central question of this study? Exercise can stimulate brown adipose tissue (BAT) with subsequent increase in uncoupling protein 1 expression and mitochondrial biogenesis. In that case, do BAT-specific Hox genes modify BAT functioning and cause uncoupling protein expression changes due to exerc...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP089114

    authors: Kato H,Ario T,Kishida T,Tadano M,Osawa S,Maeda Y,Takakura H,Izawa T

    更新日期:2020-12-28 00:00:00

  • Effects of short-term heat acclimation on whole-body heat exchange and local nitric oxide synthase- and cyclooxygenase-dependent heat loss responses in exercising older men.

    abstract:NEW FINDINGS:What is the central question of this study? Does short-term heat acclimation enhance whole-body evaporative heat loss and augment nitric oxide synthase (NOS)-dependent cutaneous vasodilatation and NOS- and cyclooxygenase (COX)-dependent sweating, in exercising older men? What is the main finding and its im...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP089025

    authors: Fujii N,McGarr GW,Notley SR,Boulay P,Sigal RJ,Amano T,Nishiyasu T,Poirier MP,Kenny GP

    更新日期:2020-12-21 00:00:00

  • Human amniotic membrane mesenchymal stem cell-conditioned medium reduces inflammatory factors and fibrosis in ovalbumin-induced asthma in mice.

    abstract:NEW FINDINGS:What is the central question of this study? Is mesenchymal stem cell-conditioned medium capable of improving the pathological alterations of ovalbumin-induced asthma in mice? What is the main finding and its importance? Our study indicated that human amniotic membrane mesenchymal stem cell-conditioned medi...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088911

    authors: Dalouchi F,Falak R,Bakhshesh M,Sharifiaghdam Z,Azizi Y,Aboutaleb N

    更新日期:2020-12-01 00:00:00

  • Ventricular contraction and relaxation rates during muscle metaboreflex activation in heart failure: are they coupled?

    abstract:NEW FINDINGS:What is the central question of this study? Does the muscle metaboreflex affect the ratio of left ventricular contraction/relaxation rates and does heart failure impact this relationship. What is the main finding and its importance? The effect of muscle metaboreflex activation on the ventricular relaxation...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP089053

    authors: Mannozzi J,Massoud L,Kaur J,Coutsos M,O'Leary DS

    更新日期:2020-11-23 00:00:00

  • Age-related electrophysiological changes in mouse taste receptor cells.

    abstract:NEW FINDINGS:What is the central question of this study? Loss of taste or inability to distinguish between different tastes progresses with age. The purpose was to evaluate the age-dependent changes in taste by studying the electrophysiological properties of taste receptor cells. What is the main finding and its import...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP089104

    authors: Takeuchi K,Yoshii K,Ohtubo Y

    更新日期:2020-11-10 00:00:00

  • Activation of the 5-HT7 receptor but not nitric oxide synthase is necessary for chronic 5-hydroxytryptamine-induced hypotension.

    abstract:NEW FINDINGS:What is the central question of this study? What mechanisms account for the hypotension observed during chronic elevations in circulating 5-hydroxytryptamine in rats? What is the main finding and its importance? Chronic 5-hydroxytryptamine-induced hypotension requires continued activation of the 5-HT7 rece...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088919

    authors: Seitz BM,Fink GD,Watts SW

    更新日期:2020-10-14 00:00:00

  • Human immune cell mobilization during exercise: effect of IL-6 receptor blockade.

    abstract:NEW FINDINGS:What is the central question of this study? Does blockade of the IL-6 receptor by tocilizumab inhibit immune cell mobilization to the blood stream in humans during an acute bout of exercise? What is the main finding and its importance? Blockade of IL-6 receptor signalling by tocilizumab attenuates mobiliza...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088864

    authors: Bay ML,Heywood S,Wedell-Neergaard AS,Schauer T,Lehrskov LL,Christensen RH,Legård GE,Jensen PØ,Krogh-Madsen R,Ellingsgaard H

    更新日期:2020-10-02 00:00:00

  • hsa_circ_001653 up-regulates NR6A1 expression and elicits gastric cancer progression by binding to microRNA-377.

    abstract:NEW FINDINGS:What is the central question of this study? Does hsa_circ_001653 influence the development of gastric cancer (GC) and if so how? What is the main finding and its importance? Bioinformatics analysis revealed the presence of differentially expressed hsa_circ_001653 in GC and adjacent normal tissues, and this...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088399

    authors: Zhou W,Jiang R,Wang Y,Li Y,Sun Z,Zhao H

    更新日期:2020-10-02 00:00:00

  • Ageing augments β-adrenergic cutaneous vasodilatation differently in men and women, with no effect on β-adrenergic sweating.

    abstract:NEW FINDINGS:What is the central question of this study? β-Adrenergic receptor activation modulates cutaneous vasodilatation and sweating in young adults. In this study, we assessed whether age-related differences in β-adrenergic regulation of these responses exist and whether they differ between men and women. What is...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088583

    authors: Fujii N,McGarr GW,Amano T,Sigal RJ,Boulay P,Nishiyasu T,Kenny GP

    更新日期:2020-10-01 00:00:00

  • Oestradiol affects skeletal muscle mass, strength and satellite cells following repeated injuries.

    abstract:NEW FINDINGS:What is the central question of this study? Oestradiol (E2 ) plays an important role in regulating skeletal muscle strength in females. To what extent does E2 deficiency affect recovery of strength and satellite cell number when muscle is challenged by multiple injuries? What is the main finding and its im...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088827

    authors: Larson AA,Baumann CW,Kyba M,Lowe DA

    更新日期:2020-10-01 00:00:00

  • Breath holding as an example of extreme hypoventilation: experimental testing of a new model describing alveolar gas pathways.

    abstract:NEW FINDINGS:What is the central question of this study? We modelled the alveolar pathway during breath holding on the hypothesis that it follows a hypoventilation loop on the O2 -CO2 diagram. What is the main finding and its importance? Validation of the model was possible within the range of alveolar gas compositions...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088977

    authors: Taboni A,Fagoni N,Fontolliet T,Grasso GS,Moia C,Vinetti G,Ferretti G

    更新日期:2020-09-29 00:00:00

  • Impaired pulmonary gas exchange efficiency, but normal pulmonary artery pressure increases, with hypoxia in men and women with a patent foramen ovale.

    abstract:NEW FINDINGS:What is the central question of this study? Do individuals with a patent foramen ovale (PFO+ ) have a larger alveolar-to-arterial difference in P O 2 ...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088750

    authors: Duke JW,Beasley KM,Speros JP,Elliott JE,Laurie SS,Goodman RD,Futral E,Hawn JA,Lovering AT

    更新日期:2020-09-01 00:00:00

  • Natural killer cell mobilization and egress following acute exercise in men with prostate cancer.

    abstract:NEW FINDINGS:What is the central question of this study? What are the characteristics of the NK cell response following acute moderate-intensity aerobic exercise in prostate cancer survivors and is there a relationship between stress hormones and NK cell mobilization? What is the main finding and its importance? NK cel...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088627

    authors: Hanson ED,Sakkal S,Que S,Cho E,Spielmann G,Kadife E,Violet JA,Battaglini CL,Stoner L,Bartlett DB,McConell GK,Hayes A

    更新日期:2020-09-01 00:00:00

  • Analgesic effect of dexmedetomidine in rats after chronic constriction injury by mediating microRNA-101 expression and the E2F2-TLR4-NF-κB axis.

    abstract:NEW FINDINGS:What is the central question of this study? Dexmedetomidine has a capacity for sedation, anti-anxiety and analgesia with minimal suppression of respiratory function; what is its role in neuropathic pain and what is the involvement of miRNAs? What is the main finding and its importance? Dexmedetomidine atte...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088596

    authors: Zhang W,Yu T,Cui X,Yu H,Li X

    更新日期:2020-09-01 00:00:00

  • The gut hormone secretin triggers a gut-brown fat-brain axis in the control of food intake.

    abstract:NEW FINDINGS:What is the topic of this review? Brown fat's role in meal-associated thermogenesis and the related consequences for energy balance regulation with a focus on the gut hormone secretin, which has been identified as the endocrine molecular mediator of meal-associated brown fat thermogenesis. What advances do...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087878

    authors: Schnabl K,Li Y,Klingenspor M

    更新日期:2020-08-01 00:00:00

  • The role of carotid bodies in the generation of active inspiratory and expiratory responses to exercise in rats.

    abstract:NEW FINDINGS:What is the central question of this study? What is the carotid bodies' contribution to active inspiratory and expiratory response to exercise? What is the main finding and its importance? Removal of the carotid bodies reduced the active inspiratory and expiratory responses of diaphragm and abdominal inter...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088203

    authors: Spiller PF,da Silva CAA,Francescato HDC,Moraes DJA

    更新日期:2020-08-01 00:00:00

  • Sitting decreases endothelial microparticles but not circulating angiogenic cells irrespective of lower leg exercises: a randomized cross-over trial.

    abstract:NEW FINDINGS:What is the central question of this study? What are the cellular and molecular determinants of increased risk for cardiovascular disease from prolonged sitting? What is the main finding and its importance? Prolonged sitting, independent of calf raise interruption strategies, decreases microparticle counts...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088690

    authors: Evans WS,Hanson ED,Shill DD,Landers-Ramos RQ,Stoner L,Willey Q,Credeur DP,Prior SJ

    更新日期:2020-08-01 00:00:00

  • Short-term very low caloric intake causes endothelial dysfunction and increased susceptibility to cardiac arrhythmias and pathology in male rats.

    abstract:NEW FINDINGS:What is the central question of this study? What are the effects of a 2 week period of severe food restriction on vascular reactivity of resistance arteries and on cardiac structure and function? What is the main finding and its importance? This study showed, for the first time, that a 2 week period of sev...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088434

    authors: Almeida JFQ,Shults N,de Souza AMA,Ji H,Wu X,Woods J,Sandberg K

    更新日期:2020-07-01 00:00:00

  • A pilot study to investigate the associations of urinary concentrations of NO, ATP and derivatives with overactive bladder symptom severity.

    abstract:NEW FINDINGS:What is the central question of this study? Are the urinary concentrations of NO and ATP, and their metabolites, associated with the severity of symptoms of overactive bladder? What is the main finding and its importance? The urinary ratios of [ATP/NO], [ADP/NO] and a combination of these, [ATP/Cr*ADP/Cr]/...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088450

    authors: Firouzmand S,Young JS

    更新日期:2020-06-01 00:00:00

  • MicroRNA-424-5p regulates aortic smooth muscle cell function in atherosclerosis by blocking APOC3-mediated nuclear factor-κB signalling pathway.

    abstract:NEW FINDINGS:What is the central question of this study? What is the role of microRNA-424-5p (miR-424-5p) in aortic smooth muscle cells? How does miR-424-5p function as a suppressor of the inflammatory response? What is the main finding and its importance? Upregulation of miR-424-5p inhibits the inflammatory response i...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088088

    authors: Li C,Zhang M,Dai Y,Xu Z

    更新日期:2020-06-01 00:00:00

  • Bionic women and men - Part 1: Cardiovascular lessons from heart failure patients implanted with left ventricular assist devices.

    abstract:NEW FINDINGS:What is the topic of this review? Patients with advanced heart failure who are implanted with left ventricular assist devices (LVADs) present an opportunity to understand the human circulation under extreme conditions. What advances does it highlight? LVAD patients have a unique circulation that is charact...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088323

    authors: Stöhr EJ,Cornwell WK 3rd,Kanwar M,Cockcroft JR,McDonnell BJ

    更新日期:2020-05-01 00:00:00

  • Long non-coding RNA PRRT3-AS1 silencing inhibits prostate cancer cell proliferation and promotes apoptosis and autophagy.

    abstract:NEW FINDINGS:What is the central question of this study? What is the role of lncRNA PRRT3-AS1 in the regulation of peroxisome proliferator-activated receptor γ (PPARγ) gene-mediated mechanistic target of rapamycin (mTOR) signalling pathway in proliferation, apoptosis and autophagy of prostate cancer cells? What is the ...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088011

    authors: Fan L,Li H,Wang W

    更新日期:2020-05-01 00:00:00

  • microRNA-143-3p regulates odontogenic differentiation of human dental pulp stem cells through regulation of the osteoprotegerin-RANK ligand pathway by targeting RANK.

    abstract:NEW FINDINGS:What is the central question of this study? What is the role of miR-143-3p during human dental pulp stem cell (hDPSC) differentiation. What is the main finding and its importance? miR-143-3p negatively regulates receptor activator of nuclear factor-κB (RANK). RANK ligand (RANKL) binds to RANK and stimulate...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087992

    authors: Yang C,Jia R,Zuo Q,Zheng Y,Wu Q,Luo B,Lin P,Yin L

    更新日期:2020-05-01 00:00:00

  • Exercise and insulin-like growth factor 1 supplementation improve angiogenesis and angiogenic cytokines in a rat model of diabetes-induced neuropathy.

    abstract:NEW FINDINGS:What is the central question of this study? Do changes in levels of angiogenesis-related mediators [vascular endothelial growth factor-A (VEGF-A), thrombospondin-1 (TSP-1) and nuclear factor-κB (NF-κB)] in the sciatic nerve mediate diabetic neuropathy in the streptozotocin-induced type 1 diabetic male rat?...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088069

    authors: Saboory E,Gholizadeh-Ghaleh Aziz S,Samadi M,Biabanghard A,Chodari L

    更新日期:2020-05-01 00:00:00

  • Exercise intolerance in heart failure: The important role of pulmonary hypertension.

    abstract:NEW FINDINGS:What is the topic of this review? This review concerns the negative impact of pulmonary hypertension (PH) on the pulmonary haemodynamic and gas exchange responses to exercise, considering the mechanisms by which PH plays a role in exercise intolerance in heart failure (HF) patients. What advances does it h...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088105

    authors: Taylor BJ,Shapiro BP,Johnson BD

    更新日期:2020-02-24 00:00:00

  • Shear-thinning behaviour of blood in response to active hyperaemia: Implications for the assessment of arterial shear stress-mediated dilatation.

    abstract:NEW FINDINGS:What is the central question of this study? Quantitative values of shear rate-specific blood viscosity and shear stress in the human macrovasculature in response to exercise hyperaemia are unknown. What is the main finding and its importance? Using the handgrip exercise model, we showed that an increase in...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP088226

    authors: Leo JA,Simmonds MJ,Sabapathy S

    更新日期:2020-02-01 00:00:00

  • Creatine supplementation improves performance above critical power but does not influence the magnitude of neuromuscular fatigue at task failure.

    abstract:NEW FINDINGS:What is the central question of this study? Does the magnitude of neuromuscular fatigue depend on the amount of work done (W') at task failure when cycling above critical power (CP)? What is the main finding and its importance? Creatine supplementation increases W' and enhances supra-CP performance, but in...

    journal_title:Experimental physiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1113/EP087886

    authors: Schäfer LU,Hayes M,Dekerle J

    更新日期:2019-12-01 00:00:00

  • Metabolic plasticity mediates differential responses to spring and autumn migrations: Evidence from gene expression patterns in migratory buntings.

    abstract:NEW FINDINGS:What is the central question of this study? What are the molecular underpinnings of seasonal metabolic plasticity during spring and autumn migrations in songbirds? What is the main finding and its importance? We report differences in mRNA levels of genes involved in the regulation of glucose and fat metabo...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087974

    authors: Sharma A,Kumar V

    更新日期:2019-12-01 00:00:00

  • Oestrogen receptor ERα and ERβ agonists ameliorate oxidative brain injury and improve memory dysfunction in rats with an epileptic seizure.

    abstract:NEW FINDINGS:What is the central question of this study? Could different hormonally active substances, including oestrogen receptor (ER) agonists, protect against oxidative brain damage and memory impairment induced by a single epileptic seizure in rats? If so, which signalling mechanisms are involved in their anti-inf...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087986

    authors: Koyuncuoğlu T,Arabacı Tamer S,Erzik C,Karagöz A,Akakın D,Yüksel M,Yeğen BÇ

    更新日期:2019-12-01 00:00:00

  • Tactile priming accelerates conscious access to continuous flash-suppressed characters.

    abstract:NEW FINDINGS:What is the central question of this study? Research has reported that some sensory input, such as auditory and olfactory input, can affect subliminal visual processing. However, it is important to address whether tactile input, another form of elementary sensory input, could influence the interocular riva...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087944

    authors: Lang Y,Gao M,Huang Q,Liu Z,Wu L,Tang R

    更新日期:2019-11-01 00:00:00

  • Control of exercise hyperpnoea: Contributions from thin-fibre skeletal muscle afferents.

    abstract:NEW FINDINGS:What is the topic of this review? In this review, we examine the evidence for control mechanisms underlying exercise hyperpnoea, giving attention to the feedback from thin-fibre skeletal muscle afferents, and highlight the frequently conflicting findings and difficulties encountered by researchers using a ...

    journal_title:Experimental physiology

    pub_type: 杂志文章,评审

    doi:10.1113/EP087649

    authors: Bruce RM,Jolley C,White MJ

    更新日期:2019-11-01 00:00:00

  • Combined treatment of dipeptidyl peptidase-4 inhibitor and exercise training improves lipid profile in KK/Ta mice.

    abstract:NEW FINDINGS:What is the central question of this study? Exercise for type 2 diabetes patients treated with insulin therapy involves the risk of hypoglycaemia. Dipeptidyl peptidase-4 (DPP-4) inhibitors can be effective in combination with exercise because they reduce the incidence of hypoglycaemia. We evaluated the eff...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087449

    authors: Tanimura Y,Aoi W,Mizushima K,Higashimura Y,Naito Y

    更新日期:2019-07-01 00:00:00

  • Enhancement of mouse diaphragm contractility in the presence of antagonists of GABAA and GABAB receptors.

    abstract:NEW FINDINGS:What is the central question of this study? Do GABA receptors play any role at the neuromuscular junction? What is the main finding and its importance? In the presence of either ionotropic or metabotropic GABA receptor antagonists, diaphragm muscle force production elicited by stimulating the motor nerve a...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087611

    authors: Lenina O,Petrov K,Kovyazina I,Malomouzh A

    更新日期:2019-07-01 00:00:00

  • The integrity of the FOG-2 LXCXE pRb-binding motif is required for small intestine homeostasis.

    abstract:NEW FINDINGS:What is the central question of this study? Do Fog2Rb-/Rb- mice present a defect of small intestine homeostasis? What is the main finding and its importance? The importance of interactions between FOG-2 and pRb in adipose tissue physiology has previously been demonstrated. Here it is shown that this intera...

    journal_title:Experimental physiology

    pub_type: 杂志文章

    doi:10.1113/EP087369

    authors: Goupille O,Kadri Z,Langelé A,Luccantoni S,Badoual C,Leboulch P,Chrétien S

    更新日期:2019-07-01 00:00:00

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