abstract：BACKGROUND:Deterioration in quality of platelet concentrates (PCs) during storage results from the appearance of storage lesions affecting the hemostatic functions and posttransfusion survival of platelets. These lesions depend on the preparation and pathogen inactivation methods used, duration of storage, and platelet...

journal_title：Transfusion

authors： Isola H,Ravanat C,Rudwill F,Pongerard A,Haas D,Eckly A,Gachet C,Hechler B

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:To quantify the impact of the US President's Emergency Plan for AIDS Relief (PEPFAR) on the risk of HIV transmission through infected blood donations in countries supported by PEPFAR blood safety programs. METHODS:Data reported to the World Health Organization Global Database on Blood Safety were analyzed f...

journal_title：Transfusion

authors： Mili FD,Teng Y,Shiraishi RW,Yu J,Bock N,Drammeh B,Watts DH,Benech I

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:Whole blood donors may experience post-donation symptoms such as fatigue, dizziness, or headache after blood donation, which could influence donor retention. We aimed to examine post-donation symptoms during 1 week after whole blood donation, investigate donor characteristics associated with symptoms, and ev...

journal_title：Transfusion

authors： Sweegers MG,Twisk JWR,Quee FA,Ferguson E,van den Hurk K

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:In December 2015, the men who have sex with men (MSM) deferral was reduced to 12 months in the United States. We compared human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) incidence and residual risk before and after this policy change using data from >50% of the US blo...

journal_title：Transfusion

authors： Steele WR,Dodd RY,Notari EP,Haynes J,Anderson SA,Williams AE,Reik R,Kessler D,Custer B,Stramer SL,Transfusion-Transmissible Infections Monitoring System (TTIMS).

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Platelets pose the greatest transfusion-transmitted infectious risk among blood products. Refrigeration of platelets can mitigate bacterial contamination and extend platelet shelf life. Implementation of pathogen reduction technologies (PRTs) at blood banks has become increasingly popular to protect against ...

journal_title：Transfusion

authors： Agey A,Reddoch-Cardenas K,McIntosh C,Sharma U,Cantu C,Cap A,Bynum J

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:At Canadian Blood Services, platelet concentrate (PC) shelf life was extended to 7 days with a large-volume, delayed-sampling bacterial screening algorithm. We present the development study and postimplementation results. STUDY DESIGN AND METHODS:In the development study, PCs inoculated with five bacteria (...

journal_title：Transfusion

authors： Ramirez-Arcos S,Evans S,McIntyre T,Pang C,Yi QL,DiFranco C,Goldman M

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:ABO-incompatible red blood cell (RBC) transfusions and acute hemolytic reactions occur infrequently, yet resultant fatalities are reported to the US Food and Drug Administration (FDA) every year. We describe a 20-year retrospective study of reported mistransfusion cases to identify temporal trends, common ca...

journal_title：Transfusion

authors： Storch EK,Rogerson B,Eder AF

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:With the coronavirus disease 2019 (COVID-19) pandemic continuing to accelerate and blood collection agencies (BCAs) warning of shortages, it is critical to identify the current determinants of donor behavior for donors and nondonors. STUDY DESIGN AND METHODS:In May and June 2020, Australian residents who be...

journal_title：Transfusion

authors： Masser BM,Hyde MK,Ferguson E

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:This study compared the likelihood of return to donate and donation rate ratio by age of donors at their first donation when followed up to 12 years. STUDY DESIGN AND METHODS:Donation history of two cohorts of first-time donors (those donating in 2007 and 2013) was extracted until March 2019 from Australian...

journal_title：Transfusion

authors： Priyono A,Masser BM,Dyda A,Davison TE,Irving DO,Karki S

更新日期：2020-11-12 00:00:00

abstract：BACKGROUND:During the COVID-19 outbreak, most hospitals deferred elective surgical procedures to allow space for the overwhelming number of COVID-19 patient admissions, expecting a decrease in routine blood component requirements. However, because transfusion support needs of COVID-19 patients are not well known, its i...

journal_title：Transfusion

authors： Velázquez-Kennedy K,Luna A,Sánchez-Tornero A,Jiménez-Chillón C,Jiménez-Martín A,Vallés Carboneras A,Tenorio M,García García I,López-Jiménez FJ,Moreno-Jiménez G

更新日期：2020-11-04 00:00:00

abstract：:Japanese encephalitis virus (JEV) is endemic to tropical areas in Asia and the Western Pacific. It can cause fatal encephalitis, although most infected individuals are asymptomatic. JEV is mainly transmitted to humans through the bite of an infected mosquito, but can also be transmitted through blood transfusion. To m...

journal_title：Transfusion

authors： Rustanti L,Hobson-Peters J,Colmant AMG,Hall RA,Young PR,Reichenberg S,Tolksdorf F,Sumian C,Gravemann U,Seltsam A,Marks DC,Faddy HM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:The Verax PGD rapid test for bacteria in platelets (PLTs) has been updated to simplify workflow and improve specificity and sensitivity by employing a novel sequential format. The performance of this updated version, called PGDprime, was evaluated to determine its suitability for use as an FDA-cleared "safet...

journal_title：Transfusion

authors： Vallejo RP,Shinefeld L,LaVerda D,Best N,Lawrence G,Lousararian A,Hornbaker N,Rasmusson P,Mintz PD

更新日期：2020-11-01 00:00:00

abstract：:Anemia is common in pregnant women and is associated with increased morbidity for the mother and the fetus, including increased risk of allogeneic blood transfusion. Iron deficiency is the most common etiology for anemia during pregnancy. Oral iron therapy remains the standard treatment but is often poorly tolerated d...

journal_title：Transfusion

authors： Guinn NR,Cooter ML,Maisonave Y,Grimsley A,Cellura C,Grotegut CA,Lamon A,Aronson S,Duke Perioperative Enhancement Team (POET).

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Hemoglobin (Hb)-based oxygen (O2 ) carriers (HBOCs) are being developed as alternatives to red blood cells and blood when these products are unavailable. Clinical trials of previous HBOC generations revealed side effects, including hypertension and vasoconstriction, that were not observed in preclinical stud...

journal_title：Transfusion

authors： Muller CR,Williams AT,Munoz CJ,Eaker AM,Breton AN,Palmer AF,Cabrales P

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:Chikungunya (CHIKV), dengue (DENV), and Zika (ZIKV) viruses are of concern due to the potential of transfusion transmission in blood, especially in regions such as Southeast Asia where the viruses are endemic. The recent availability of nucleic acid testing (NAT) to screen blood donations on an automated pla...

journal_title：Transfusion

authors： Stanley J,Chongkolwatana V,Duong PT,Kitpoka P,Stramer SL,Dung NTT,Grimm KE,Pojanasingchod A,Suksomboonvong P,Galel SA

更新日期：2020-10-07 00:00:00

abstract：:Transfusion of an incorrect blood component is an important avoidable serious hazard of transfusion resulting from process errors. Our group and others have taken advantage of new technology and developed electronic transfusion systems for safe transfusion practice in a previous studies. They allow the clinical staff ...

journal_title：Transfusion

authors： Staples S,O'Callaghan C,Pavord S,Staves J,Murphy MF

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Although the need for whole blood is declining, so too are the number of first-time and repeat blood donors. To develop new recruitment and retention strategies, therefore, we need to draw on as wide a variation in blood donor motivations as possible. The primary aim of this study is to draw on a large surve...

journal_title：Transfusion

authors： Ferguson E,Hill A,Lam M,Reynolds C,Davison K,Lawrence C,Brailsford SR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Sickle cell disease (SCD) is associated with hematologic complications including delayed hemolytic transfusion reactions (DHTRs) and pregnancy-related morbidity and mortality. Hyperhemolysis syndrome (HS) is the most severe form of DHTR in patients with SCD, in which both transfused and native red blood cell...

journal_title：Transfusion

authors： Vasanthamohan L,Choo S,Marshall T,Symons YT,Matsui D,Eastabrook G,Solh Z

更新日期：2020-08-26 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：BACKGROUND:Hypothermic storage transforms red blood cells (RBC) from smooth biconcave discocytes into increasingly spherical spiculated echinocytes and, ultimately, fragile spherocytes (S). Individual cells undergo this transformation at different rates, producing a heterogeneous mixture of RBCs at all stages of echino...

journal_title：Transfusion

authors： Lu M,Shevkoplyas SS

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Growth in size and complexity of clinical hematopoietic progenitor cell (HPC) transplant programs necessitates parallel increases in cellular therapy laboratory (CTL) workload. Typically individually developed, HPC product processing is labor and time intensive. Variation in procedure type and numbers across...

journal_title：Transfusion

authors： Thibodeaux SR,McKenna DH,Szczepiorkowski ZM,Fontaine MJ,Kelley L,Reems JA,Young PP,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Blood collection centers are charged with creating donor educational materials (DnEM) that are easily understood across all prospective donor populations, while addressing mandates and recommendations from regulatory agencies and professional standard setting organizations. Donors must have sufficient inform...

journal_title：Transfusion

authors： Wehrli G,Rossmann SN,Waxman DA,Katz LM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Whole blood donors are at risk of becoming iron deficient. To monitor iron stores, Sanquin implemented a new deferral policy based on ferritin levels, in addition to the traditional hemoglobin measurements. METHODS:Ferritin levels are determined in every fifth donation, as well as in all first-time donors. ...

journal_title：Transfusion

authors： Vinkenoog M,van den Hurk K,van Kraaij M,van Leeuwen M,Janssen MP

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Very preterm newborns receive up to three to five red blood cell (RBC) transfusions, often early, after birth. Despite awareness of the association of transfusion with increases in cytokines and markers of endothelial activation, research has focused on single transfusions weeks after birth. With pathophysio...

journal_title：Transfusion

authors： Crawford TM,Andersen CC,Stark MJ

更新日期：2020-07-25 00:00:00

abstract：BACKGROUND:In the pandemic, testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by real-time polymerase chain reaction is one of the pillars on which countermeasures are based. Factors limiting the output of laboratories interfere with the effectiveness of public health measures. Conserving reagent...

journal_title：Transfusion

authors： Schmidt M,Hoehl S,Berger A,Zeichhardt H,Hourfar K,Ciesek S,Seifried E

更新日期：2020-07-06 00:00:00

abstract：BACKGROUND:The AABB Clinical Transfusion Medicine Committee (CTMC) compiles an annual synopsis of the published literature covering important developments in the field of transfusion medicine (TM) for the board of director's review. This synopsis is now made available as a manuscript published in TRANSFUSION. STUDY DE...

journal_title：Transfusion

authors： Pagano MB,Allen ES,Chou ST,Dunbar NM,Gniadek T,Goel R,Harm SK,Hopkins CK,Jacobson J,Lokhandwala PM,Metcalf RA,Raval JS,Schwartz J,Shan H,Spinella PC,Storch E,Cohn CS

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:In 2014, we experienced the first isolation of Lactococcus garvieae from a platelet concentrate (PC). Thereafter, L. garvieae contamination of PCs occurred in two more cases in Japan. It is rare that bacterial contamination with uncommon strains like this species occurs frequently within a short period. Ther...

journal_title：Transfusion

authors： Kozakai M,Matsumoto C,Matsumoto M,Takakura A,Matsubayashi K,Satake M

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Point-of-issue tests, such as the Verax Pan Genera Detection (PGD) test, can be used to mitigate the occurrence of septic reactions. Little is known about how widespread the adoption of the PGD test is across US hospitals. STUDY DESIGN/METHODS:The Red Cross hemovigilance database was used to determine the n...

journal_title：Transfusion

authors： Rios J,Westra J,Dy B,Young PP

更新日期：2020-07-01 00:00:00

abstract：:Pathogen inactivation/reduction technologies for platelet components have been developed to enhance microbial safety, and many studies have been carried out to determine whether this technique adversely affects the platelet's ability to stop or prevent bleeding. These clinical trials require inclusion of several hundr...

journal_title：Transfusion

authors： Heddle NM,Cardoso M,van der Meer PF

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Frozen plasma is superior to crystalloids for hemorrhage resuscitation but remains logistically challenging in austere environments because of specialized clinical equipment for on-demand thawing. This research examines some ad hoc thawing techniques that have been implemented by military medical personnel...

journal_title：Transfusion

authors： Meledeo MA,Peltier GC,McIntosh CS,Corley JB,Bynum JA,Cap AP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Acute trauma coagulopathy (ATC) after military trauma has not been comprehensively studied. ATC is defined as a prolonged prothrombin time ratio (PTr) or reduced clot amplitude (A5) in viscoelastic testing. Compared to civilian trauma, military trauma has more injuries from explosions and gunshot wounds (GSW...

journal_title：Transfusion

authors： Woolley T,Gwyther R,Parmar K,Kirkman E,Watts S,Midwinter M,Lucca JD,Hunt BJ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Low-titer group O whole blood (LTOWB) is increasingly being used in the civilian trauma setting, although there is a risk of hemolysis. This study evaluated the impact on hemolytic markers following the transfusion of 4 or more units of uncrossmatched LTOWB. METHODS:Civilian adult trauma patients who receiv...

journal_title：Transfusion

authors： Harrold IM,Seheult JN,Alarcon LH,Corcos A,Sperry JL,Triulzi DJ,Yazer MH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Conventional platelet (PLT) storage at room temperature under continuous agitation results in a limited shelf life (5 days) and an increased risk of bacterial contamination. However, both of these aspects can be ameliorated by cold storage. Preliminary work has suggested that PLTs can be cold stored for up t...

journal_title：Transfusion

authors： D'Alessandro A,Thomas KA,Stefanoni D,Gamboni F,Shea SM,Reisz JA,Spinella PC

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Phlebotomy is among the main determinants of anemia of prematurity. Blood sparing policies endorsed umbilical cord blood (here called placental) as an alternative source for laboratory testing. Little is known on the suitability of placental blood to evaluate neonatal hemostasis of newborn infants. We aimed ...

journal_title：Transfusion

authors： Raffaeli G,Tripodi A,Manzoni F,Scalambrino E,Pesenti N,Amodeo I,Cavallaro G,Villamor E,Peyvandi F,Mosca F,Ghirardello S

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservation, but HSC products also contain various cells and plasma components. Our recent prospective study of 1125 ...

journal_title：Transfusion

authors： Ikeda K,Ohto H,Yamada-Fujiwara M,Okuyama Y,Fujiwara SI,Muroi K,Mori T,Kasama K,Kanamori H,Iseki T,Nagamura-Inoue T,Kameda K,Kanda J,Nagai K,Fujii N,Ashida T,Hirose A,Takahashi T,Minakawa K,Tanosaki R

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Some jurisdictions require leukoreduction of cellular blood components. The only whole blood collection set with a platelet-saving filter uses citrate-phosphate-dextrose (CPD) as storage solution. Substituting CPD with citrate-phosphate-dextrose-adenine (CPDA-1) increases shelf life from 21 to 35 days. This ...

journal_title：Transfusion

authors： Sivertsen J,Braathen H,Lunde THF,Kristoffersen EK,Hervig T,Strandenes G,Apelseth TO

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Neutrophil specific Fcγ receptor IIIb (CD16b) is a low-affinity IgG receptor. Its polymorphic variants are associated with human neutrophil antigens (HNA). HNA-1a and HNA-1b differ in four amino acids. Immunization can lead to the production of alloantibodies. The exact contribution of four amino acid exchan...

journal_title：Transfusion

authors： Sachs UJ,Radke C,Bein G,Grabowski C,Simtong P,Bux J,Bayat B,Reil A

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Understanding factors that impact tissue oxygen extraction may guide red blood cell (RBC) transfusion decision making in preterm infants. Our objective was to assess the influence of enteral feeding and anemia on cerebral and mesenteric oxygen saturation (Csat and Msat) and fractional tissue oxygen extractio...

journal_title：Transfusion

authors： Goldstein GP,Rao A,Ling AY,Ding VY,Chang IJ,Chock VY

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Among labile blood products, platelet concentrates (PCs) are the leading cause of hypersensitivity transfusion reactions (HTRs). These reactions often lead to interruption of PC transfusion and can result in a prolonged transfusion process leading to significant morbidity and use of premedication and close m...

journal_title：Transfusion

authors： Mertes PM,Tacquard C,Andreu G,Kientz D,Gross S,Malard L,Drouet C,Carlier M,Gachet C,Sandid I,Boudjedir K

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Blood transfusion is the first-line treatment for patients with thalassemia and many sickle cell patients. However, cases of unregulated blood transfusion are shown to carry a high risk of alloimmunization to red blood cells (RBCs), which can lead to a hemolytic transfusion reaction and be fatal to patients....

journal_title：Transfusion

authors： Hindawi S,Badawi M,Elfayoumi R,Elgemmezi T,Al Hassani A,Raml M,Alamoudi S,Gholam K

更新日期：2020-02-01 00:00:00