Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion.

abstract：BACKGROUND:Previous studies showed that Mirasol (Navigant Biotechnologies, Inc.) pathogen reduction technology (PRT) treatment resulted in an increase in platelet (PLT) glucose consumption and lactate production rates and decrease in pH in media during PLT storage. Increased glycolytic flux could result from damage to ...

journal_title：Transfusion

authors： Li J,Lockerbie O,de Korte D,Rice J,McLean R,Goodrich RP

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Full siblings were compared with half-siblings to observe how well the two relationships could be distinguished by informative tests. STUDY AND DESIGN METHODS: Parentage analysis ascertained 25 pairs of full siblings and 25 pairs of half-siblings. The pairs were then examined for the sharing of alleles at th...

journal_title：Transfusion

authors： Wenk RE,Chiafari FA

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The serological safety of transfusing ≤4 units of low titer group O whole blood (LTOWB) in civilian trauma patients has been demonstrated. This study investigated clinical outcomes of LTOWB recipients compared to patients who received only conventional blood components during their resuscitation. STUDY DESI...

journal_title：Transfusion

authors： Seheult JN,Anto V,Alarcon LH,Sperry JL,Triulzi DJ,Yazer MH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Transfusion of bacterially contaminated platelet concentrates (PCs) can result in serious health consequences for the affected patient. Before being released from blood banking facilities, PCs are routinely screened for bacterial contamination by culture-based tests. However, culture-based PC screening metho...

journal_title：Transfusion

authors： Zweitzig DR,Riccardello NM,Pester JM,Jeanmonod R,Kopnitsky MJ,O'Hara SM

更新日期：2014-06-01 00:00:00

abstract：:In Taiwan, the prevalence of circulating anti-HCV is 2 percent among first-time voluntary Chinese blood donors, 10 percent among donors with elevated ALT levels (greater than 45 IU/L), and higher among older men. The carrier rate for HBsAg was 18.6 percent and the frequency of positive HBV marker(s) (HBsAg, anti-HBc, ...

journal_title：Transfusion

authors： Lin-Chu M,Tsai SJ,Watanabe J,Nishioka K

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:After multiple transfusions, the serologic typing of autologous blood group phenotypes is difficult, because of mixed RBC populations. The genotyping of ABO, Rh, Kell, Kidd, and Duffy systems could be used to determine autologous blood group antigen status. STUDY DESIGN AND METHODS:Blood samples from patien...

journal_title：Transfusion

authors： Rozman P,Dovc T,Gassner C

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Patients with thalassemia major require iron chelation therapy (ICT) to prevent complications from transfusional iron overload. Deferoxamine is effective, but requires administration as a slow continuous subcutaneous or intravenous infusion five to seven times per week. Deferiprone is a three-times-daily ora...

journal_title：Transfusion

authors： Delea TE,Edelsberg J,Sofrygin O,Thomas SK,Baladi JF,Phatak PD,Coates TD

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:The use of hematopoietic progenitor cell (HPC) transplantation has rapidly expanded in recent years. Currently, several sources of HPCs are available for transplantation including peripheral blood HPCs (PBPCs), cord blood cells, and marrow cells. Of these, PBPC collection has become the major source of HPCs....

journal_title：Transfusion

authors： Chen J,Burns KM,Babic A,Carrum G,Kennedy M,Segura FJ,Garcia S,Potts S,Leveque C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The Joint Commission on the Accreditation of Healthcare Organizations requires that hospitals have a planned approach to systematically collect data on processes related to the use, ordering, and administering of blood components. This study describes how a comprehensive blood-administering assessment progra...

journal_title：Transfusion

authors： Saxena S,Ramer L,Shulman IA

更新日期：2004-09-01 00:00:00

abstract：:In an attempt to gain insight into the motivations of blood donors and nondonors, two paper and pencil questionnaires were developed and mailed to approximately 7,000 individuals. In response, 1,429 nondonors and 200 donors completed and returned usable questionnaires. Among donors, awareness of the need for blood, al...

journal_title：Transfusion

authors： Leibrecht BC,Hogan JM,Luz GA,Tobias KI

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:This study reports the incidence of Wr(a) antigen and anti-Wr(a) in Valencia, Spain. STUDY DESIGN AND METHODS:The incidence of the Wr(a) antigen in 110,000 healthy blood donors was estimated. Likewise, the incidence of anti-Wr(a) was analyzed in a population consisting of 730 healthy blood donors, 356 pregn...

journal_title：Transfusion

authors： Arriaga F,Llopis F,de la Rubia J,Carpio N,Moscardó J,Marty ML

更新日期：2005-08-01 00:00:00

abstract：:A 67-year-old white woman received transfusions of a total of 87 units of whole blood and red blood cells during and within 48 hours following a pneumonectomy. Although she had previously received blood transfusions, unexpected antibodies were not detectable by routine screening. On the second postoperative day, she d...

journal_title：Transfusion

authors： Chandeysson PL,Flye MW,Simpkins SM,Holland PV

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Fresh-frozen plasma (FFP) is frequently transfused to patients with mild prolongation of coagulation values under the assumption that FFP will correct the coagulopathy. There is little evidence to support this practice, however. To determine the effect of FFP on coagulation variables and correlation with ble...

journal_title：Transfusion

authors： Abdel-Wahab OI,Healy B,Dzik WH

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The RHD gene is flanked by two highly homologous DNA segments of approximately 9000 bp, the upstream and downstream Rhesus boxes. In haplotypes with an RHD deletion, the fusion of the two Rhesus boxes generates the single-hybrid Rhesus box, the detection of which has been applied for RHD zygosity determinati...

journal_title：Transfusion

authors： Wagner FF,Moulds JM,Flegel WA

更新日期：2005-03-01 00:00:00

abstract：:Two monoclonal antibodies (MoAbs), BRIC 66 (IgM) and BRIC 111 (IgG1), were produced by immunizing mice with ovarian cyst blood group A1 glycoprotein and Tn red cells (RBCs), respectively. Their specificities were determined by inhibitions using Tn sialoglycoproteins (SGPs), mucins (armadillo [ASG] and ovine [OSG] subm...

journal_title：Transfusion

authors： King MJ,Parsons SF,Wu AM,Jones N

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Delayed hemolysis mediated by long-term production of pre-existing recipient-derived antibodies directed against donor RBC antigens after allogenic BMT is an unusual complication of hematopoietic transplantation. CASE REPORT:A 26-year-old man with aplastic anemia had pre-existing alloantibodies to E and c. ...

journal_title：Transfusion

authors： Izumi N,Fuse I,Furukawa T,Uesugi Y,Tsuchiyama J,Toba K,Togashi K,Yamada K,Ohtake S,Saitoh Y,Yanagisawa N,Aizawa Y

更新日期：2003-02-01 00:00:00

abstract：:ALX148, a novel CD47 blocking agent, is in clinical development for the treatment of advanced solid tumors and lymphoma. Because CD47 is highly expressed on red blood cells (RBCs), its therapeutic blockade can potentially interfere with pretransfusion compatibility testing. This study describes the interference of ALX...

journal_title：Transfusion

authors： Kim TY,Yoon MS,Hustinx H,Sim J,Wan HI,Kim H

更新日期：2020-08-20 00:00:00

abstract：:Red blood cells stored in saline solution for two weeks at 12 C lose some of their Fya, Fyb, and Fy3 antigenicity. At the same time substances with specific inhibitory activity against appropriate Duffy antibodies appear in the saline. Similar changes could not be recognized in time-expired commercial reagent red bloo...

journal_title：Transfusion

authors： Williams D,Johnson CL,Marsh WL

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Tests for platelet-specific antibodies are important in the diagnosis of immune platelet disorders. Monoclonal antibody glycoprotein capture assays have been the gold standards in platelet antibody detection for almost 30 years. However, such assays are complex and cumbersome to perform, which limits their r...

journal_title：Transfusion

authors： Metzner K,Bauer J,Ponzi H,Ujcich A,Curtis BR

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Coxiella burnetii, an obligate intracellular organism, is the causative agent of the zoonotic disease Q fever. The seroprevalence rate for Q fever in the United States is 3.1%, suggesting a high number of infections each year. However, fewer than 200 cases of Q fever are reported to the CDC annually. This di...

journal_title：Transfusion

authors： Kersh GJ,Priestley R,Massung RF

更新日期：2013-07-01 00:00:00

abstract：:Evidence supporting the existence of two agents of human non-A, non-B hepatitis was obtained by the inoculation of chimpanzees sequentially with serum from a chronically infected human (Inoculum I) and with fibrinogen prepared from pooled plasma (Inoculum IV), each of which had transmitted non-A, non-B hepatitis to hu...

journal_title：Transfusion

authors： Tabor E,Snoy P,Jackson DR,Schaff Z,Blatt PM,Gerety RJ

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Mobilized peripheral blood is the most common source of CD34+ cells intended for transplantations. The collection and enrichment of CD34+ cells could be affected by various factors and there are some controversies regarding the effects of patient-related factors. The aim of this study was to assess the impac...

journal_title：Transfusion

authors： Kresnik PK,Krasna M,Rozman P,Vrtovec B,Malicev E

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:There are no reports in the transfusion medicine literature that describe adverse reactions and donor arm injuries after whole-blood donation based on solicited information. STUDY DESIGN AND METHODS:The present study solicited adverse reaction and donor arm injury information from 1000 randomly selected who...

journal_title：Transfusion

authors： Newman BH,Pichette S,Pichette D,Dzaka E

更新日期：2003-05-01 00:00:00

abstract：:Japanese encephalitis virus (JEV) is endemic to tropical areas in Asia and the Western Pacific. It can cause fatal encephalitis, although most infected individuals are asymptomatic. JEV is mainly transmitted to humans through the bite of an infected mosquito, but can also be transmitted through blood transfusion. To m...

journal_title：Transfusion

authors： Rustanti L,Hobson-Peters J,Colmant AMG,Hall RA,Young PR,Reichenberg S,Tolksdorf F,Sumian C,Gravemann U,Seltsam A,Marks DC,Faddy HM

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Blood donations collected at the National Blood Center, the Thai Red Cross Society, Bangkok, in 2007 were tested by nucleic acid amplification technology (NAT) using the Chiron TIGRIS/Procleix Ultrio test and the Roche cobas s 201/cobas TaqScreen multiplex (MPX) test. STUDY DESIGN AND METHODS:The sensitivit...

journal_title：Transfusion

authors： Phikulsod S,Oota S,Tirawatnapong T,Sakuldamrongpanich T,Chalermchan W,Louisirirotchanakul S,Tanprasert S,Chongkolwatana V,Kitpoka P,Phanuphak P,Wasi C,Nuchprayoon C,Working Group for NAT Study in Thai Blood Donations.

更新日期：2009-06-01 00:00:00

abstract：:The development of flexible plastic blood bags has permitted effective blood component production and therapy. However, the plasticizer di(2-ethylhexyl)phthalate (DEHP), whose toxicity in humans is still undefined, is known to leach from the plastic into stored blood. Despite the availability of bags made of plastics ...

journal_title：Transfusion

authors： Rock G,Tocchi M,Ganz PR,Tackaberry ES

更新日期：1984-11-01 00:00:00

abstract：:Originally pasted on walls and on locations reserved specially for that purpose, the poster is a medium for advertising and promotion to be seen on the streets and in public places. More recently, it has spread, in a smaller format, on dedicated indoor sites: billboards, columns, street furniture, and so forth. For tr...

journal_title：Transfusion

authors： Lefrère JJ,Danic B

更新日期：2012-06-01 00:00:00

abstract：:An exchange transfusion was performed preoperatively on a patient with sickle cell disease using a continuous-flow blood cell separator. An exchange of 2,825 ml red blood cells achieved a hemoglobin A level of 90.8 per cent. The continuous-flow blood cell separator appears to offer a safe and effective method of excha...

journal_title：Transfusion

authors： Kernoff LM,Botha MC,Jacobs P

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Patients presenting with acute episodes of thrombotic microangiopathies (TMAs) require urgent access to plasma exchange (PEX). OctaplasLG, a solvent/detergent fresh-frozen plasma product that has undergone viral inactivation and prion reduction step, has been used in our institution since 2013, replacing Oct...

journal_title：Transfusion

authors： Vendramin C,McGuckin S,Alwan F,Westwood JP,Thomas M,Scully M

更新日期：2017-01-01 00:00:00

abstract：:Ultraviolet B (UVB) irradiation of platelet concentrates (PCs) may prevent the development of posttransfusion HLA alloimmunization. As irradiation performed in a blood center or a hospital will probably be associated with a variable postirradiation delay before transfusion, the ability to store PCs after UVB irradiati...

journal_title：Transfusion

authors： Snyder EL,Beardsley DS,Smith BR,Horne W,Johnson R,Wooten T,Napychank PA,Male P,Buchholz DH

更新日期：1991-07-01 00:00:00