abstract：BACKGROUND:Prevalence and contribution of intracranial and extracranial arterial stenosis to stroke risk were assessed prospectively in children and young adults with sickle cell disease. METHODS:In this cross-sectional study, children and young adults (mean = 19.4 years) with sickle cell disease underwent neurologica...

journal_title：Pediatric neurology

authors： Schlotman AA,Donahue MJ,Kassim AA,Lee CA,Waddle SL,Pruthi S,Davis LT,Rodeghier M,DeBaun MR,Jordan LC

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Clinically mild encephalopathy with a reversible splenial lesion (MERS) is the second commonest cause of encephalopathy. Several pathogens have been detected in patients with MERS type 2, such as influenza A and B, but little is known about the proportion of cases of MERS type 2 with this pathogenesis. Human...

journal_title：Pediatric neurology

authors： Sano F,Fukao T,Tamaru K,Kanemura H,Inukai T,Aihara M

更新日期：2020-12-01 00:00:00

abstract：:Cerebral cavernous malformations are the second most common vascular malformations in the central nervous system, and over one-third are found in children. Lesions may be solitary or multiple, be discovered incidentally, be sporadic, or be secondary to familial cavernomatosis or radiation therapy. Children may present...

journal_title：Pediatric neurology

authors： Paddock M,Lanham S,Gill K,Sinha S,Connolly DJA

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Autopsy studies in Rasmussen encephalitis reveal areas of sparing within the affected hemisphere. Clinical progression and inflammation are milder with an older onset. We sought to demonstrate radiological corroboration for these patterns. METHODS:In our retrospective study, 38 cases were dichotomized into ...

journal_title：Pediatric neurology

authors： Benjamin RN,Thomas M,Muthusamy K,Yoganathan S,Mathew V,Chacko AG,Prabhu K,Chacko G

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Acute flaccid myelitis (AFM) is a rare disease of young children. The typical presentation involves acute-onset flaccid paralysis in one or more extremities with a nonspecific viral prodrome. Long-term outcomes demonstrate that functional recovery plateaus around six to nine months. The purpose of this study...

journal_title：Pediatric neurology

authors： Paziuk TM,Tadley M,Aversano M,Kozin SH,Zlotolow DA

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:High dosages of natural adrenocorticotropic hormone are used in many centers in the United States for the treatment of infantile spasms. However, lower dosages of synthetic adrenocorticotropic hormone (tetracosactide) might be equally efficient as high dosages. We analyzed the treatment options for infantile...

journal_title：Pediatric neurology

authors： Riikonen R,Lähdetie J,Kokki H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Sturge-Weber syndrome is a neurocutaneous disorder associated with epilepsy, glaucoma, cognitive impairments, and a port-wine birthmark. Although individuals with Sturge-Weber syndrome are vulnerable to known risk factors for suicide, including chronic illness and physical differences (port-wine birthmark), ...

journal_title：Pediatric neurology

authors： Sebold AJ,Ahmed AS,Ryan TC,Cohen BA,Jampel HD,Suskauer SJ,Zabel TA,Comi AM,Rybczynski S

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To investigate clinical risk factors for acute magnetic resonance imaging (MRI) abnormalities in patients with benign convulsions with mild gastroenteritis or benign infantile epilepsy. STUDY DESIGN:We investigated clinical and diffusion-weighted imaging findings in 32 patients with benign convulsions with m...

journal_title：Pediatric neurology

authors： Ogawa C,Kidokoro H,Ishihara N,Tsuji T,Kurahashi H,Hattori A,Suzuki M,Ogaya S,Ito Y,Fukasawa T,Kubota T,Okumura A,Saitoh S,Natsume J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:It is well known that febrile seizures are commonly occur in children with exanthem subitum. In this study, we compared the clinical features and backgrounds of patients with complex febrile seizures with and without primary human herpesvirus 6B infection. METHODS:Sixty-two patients were enrolled after expe...

journal_title：Pediatric neurology

authors： Miyake M,Kawamura Y,Hattori F,Miura H,Ishihara N,Yoshikawa T

更新日期：2020-08-01 00:00:00

abstract：:Ischemic and hemorrhagic stroke can occur in the setting of pediatric trauma, particularly those with head or neck injuries. The risk of stroke appears highest within the first two weeks after trauma. Stroke diagnosis may be challenging due to lack of awareness or concurrent injuries limiting detailed neurological ass...

journal_title：Pediatric neurology

authors： Galardi MM,Strahle JM,Skidmore A,Kansagra AP,Guilliams KP

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Very-low-birth-weight preterm infants have a higher rate of language impairments compared with children born full term. Early identification of preterm infants at risk for language delay is essential to guide early intervention at the time of optimal neuroplasticity. This study examined near-term structural ...

journal_title：Pediatric neurology

authors： Vassar R,Schadl K,Cahill-Rowley K,Yeom K,Stevenson D,Rose J

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Guillain-Barré syndrome is the most common cause of acute flaccid paresis in childhood. Few validated large-scale population-based data are available concerning pediatric Guillain-Barré syndrome, including incidence, risk factors, and initial clinical characteristics. METHODS:In the Danish National Patient ...

journal_title：Pediatric neurology

authors： Levison LS,Thomsen RW,Markvardsen LK,Christensen DH,Sindrup SH,Andersen H

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:The mechanistic target of rapamycin inhibitors everolimus and sirolimus have activity against multiple manifestations of tuberous sclerosis complex and are approved to treat astrocytomas, angiomyolipomas, lymphangioleiomyomatosis, and epilepsy. Cannabidiol is a novel antiepileptic medication. There is lack o...

journal_title：Pediatric neurology

authors： Ebrahimi-Fakhari D,Agricola KD,Tudor C,Krueger D,Franz DN

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Ketamine has recently emerged as a promising therapeutic alternative for abortive migraine therapy, likely secondary to N-methyl-d-aspartate antagonism. Most reports examine adults and the intravenous route. Fewer utilize intranasal administration or pediatric populations. Given the limited evidence for intr...

journal_title：Pediatric neurology

authors： Turner AL,Shandley S,Miller E,Perry MS,Ryals B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Insomnia and low iron stores are common in children with autism spectrum disorders, and low iron stores have been associated with sleep disturbance. METHODS:We performed a randomized placebo-controlled trial of oral ferrous sulfate to treat insomnia in children with autism spectrum disorders and low normal ...

journal_title：Pediatric neurology

authors： Reynolds AM,Connolly HV,Katz T,Goldman SE,Weiss SK,Halbower AC,Shui AM,Macklin EA,Hyman SL,Malow BA

更新日期：2020-03-01 00:00:00

abstract：:Headache hygiene refers to self-management behaviors and practices aimed at reducing headache-related disability and improving self-efficacy. Although self-management interventions have an established place in the management of a wide range of chronic conditions, there is still not a standardized approach to this in p...

journal_title：Pediatric neurology

authors： Barmherzig R,Lagman-Bartolome AM,Marlowe S,Kohut SA,Gunn G,Olivieri H,Mulligan J,Grundy-Bozinis K,Gladstone J,Lay C,MacGregor D

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Pediatric patients with epilepsy are at risk for low vitamin D levels, increasing the risk for bone fractures, yet standardized bone health screening is not part of routine care. METHODS:We surveyed pediatric neurologists (n = 68) at our center regarding screening practices, using an 11-item survey; constru...

journal_title：Pediatric neurology

authors： Patel AA,An S,Schomer M,Julich K,Elitt C,Heath J,Putman MS,Loddenkemper T

更新日期：2020-01-01 00:00:00

abstract：AIM:We assessed the utilization of the National Institutes of Health Quality of Life in Neurological Disorders (Neuro-QoL) in pediatric patients with Sturge-Weber syndrome, a rare neurovascular disorder which frequently results in seizures, brain atrophy, calcification, and a range of neurological impairments. METHODS...

journal_title：Pediatric neurology

authors： Harmon KA,Day AM,Hammill AM,Pinto AL,McCulloch CE,Comi AM,National Institutes of Health Rare Disease Clinical Research Consortium (RDCRN) Brain and Vascular Malformation Consortium (BVMC) SWS Investigator Group.

更新日期：2019-12-01 00:00:00

abstract：:Acute disseminated encephalomyelitis is an inflammatory disorder of the central nervous system. Uniform diagnostic criteria for acute disseminated encephalomyelitis did not exist until publication of expert-defined consensus definitions by the International Pediatric Multiple Sclerosis Society Group in 2007, with upda...

journal_title：Pediatric neurology

authors： Cole J,Evans E,Mwangi M,Mar S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Outcome in severe acute necrotizing encephalopathy of childhood is poor, with high mortality (30%) and moderate to severe disability in survivors despite the use of intravenous corticosteroids or immunoglobulins. Increased blood interleukin 6 level correlates with poor outcome. METHODS:We report the early u...

journal_title：Pediatric neurology

authors： Koh JC,Murugasu A,Krishnappa J,Thomas T

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Acute encephalitis and encephalopathy are life-threatening diseases in children. However, no laboratory examinations are performed for their early diagnosis and treatment. Alpha 2-macroglobulin (α2M) is a blood glycoprotein that increases during the early stages of inflammation. In the present study, we inve...

journal_title：Pediatric neurology

authors： Suzuki Y,Hashimoto K,Hoshi K,Ito H,Kariya Y,Miyazaki K,Sato M,Kawasaki Y,Yoshida M,Honda T,Hashimoto Y,Hosoya M

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Patients in China with juvenile-onset myasthenia gravis present early, with a high prevalence of purely ocular symptoms, spontaneous remission rates, and low antibody seropositivity. Antibody detection using a cell-based assay has been reported to increase the diagnostic sensitivity in adult-onset myasthenia...

journal_title：Pediatric neurology

authors： Yan C,Li W,Song J,Feng X,Xi J,Lu J,Zhou S,Zhao C

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:We evaluated the frequency of six commonly reported adult migraine premonitory symptoms in children and adolescents with episodic and chronic migraine and elicited psychological or behavioral comorbidities that may be associated with these symptoms. BACKGROUND:Premonitory symptoms are commonly reported in th...

journal_title：Pediatric neurology

authors： Jacobs H,Pakalnis A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Distinguishing patients with psychogenic nonsyncopal collapse (PNSC), a conversion disorder that resembles syncope, can pose a difficult clinical challenge. Using the open-ended question "what does it feel like to faint?," the present study aimed to characterize how patients with PNSC perceive and communicat...

journal_title：Pediatric neurology

authors： Heyer GL

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Concern exists regarding a possible harmful impact of vacuum extraction on the preterm newborn. We aimed to evaluate the long-term pediatric neurodevelopmental outcomes of the preterm offspring after vacuum extraction. METHODS:A population-based cohort analysis was performed comparing the risk for long-term...

journal_title：Pediatric neurology

authors： Schwarzman P,Sheiner E,Wainstock T,Mastrolia SA,Segal I,Landau D,Walfisch A

更新日期：2019-05-01 00:00:00

abstract：:Moyamoya is a chronic, progressive steno-occlusive arteriopathy that typically affects the anterior circulation arteries of the circle of Willis. A network of deep thalamoperforating and lenticulostriate collaterals develop to by-pass the occlusion giving rise to the characteristic angiographic "puff of smoke" appeara...

journal_title：Pediatric neurology

authors： Dlamini N,Muthusami P,Amlie-Lefond C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Pediatric critical care survivors often suffer persisting multisystem health problems and are left with treatment needs that go unmet due to limits in current care models. We proposed that integration of neuropsychology into neurocritical care follow-up provides incremental benefit to the identification and ...

journal_title：Pediatric neurology

authors： Dodd JN,Hall TA,Guilliams K,Guerriero RM,Wagner A,Malone S,Williams CN,Hartman ME,Piantino J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The Hammersmith Infant Neurological Examination is one of several useful tools for early identification of cerebral palsy; however, cut-off scores for cerebral palsy do not consistently distinguish infants with hemiplegia from those typically developing. We hypothesized that use of an asymmetry score, in add...

journal_title：Pediatric neurology

authors： Hay K,Nelin M,Carey H,Chorna O,Moore-Clingenpeel Ma Mas M,Maitre N,NCH Early Developmental Group.

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to assess the sensibility of the hand in children with a neonatal brachial plexus palsy (NBPP) involving the C5 and C6, and to correlate results with dexterity. METHODS:Fifty children with NBPP (30 after nerve surgery, mean age 9.8 years) and 25 healthy controls (mean age 9.6 years...

journal_title：Pediatric neurology

authors： Buitenhuis SM,Pondaag W,Wolterbeek R,Malessy MJA

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Rituximab (anti-CD20) has been used as B-cell-targeted intervention to treat opsoclonus-myoclonus syndrome. Due to isolated reports of chronic hypogammaglobulinemia and B lymphopenia following rituximab in several disorders, and rapid B-cell depletion after a few doses, we reduced the dosage 20% in our clini...

journal_title：Pediatric neurology

authors： Pranzatelli MR,Tate ED,McGee NR,MacArthur CA

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Posterior ischemic optic neuropathy results from ischemia of the retrobulbar aspect of the optic nerve. It presents as acute loss of vision without optic disc swelling. This is rare in children, with only seven cases reported to date. Neuroimaging is frequently used to aid in the diagnosis of acute visual co...

journal_title：Pediatric neurology

authors： Harrar DB,Solomon J,Shah AS,Vaughn J,Durbin AD,Rivkin MJ

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:No therapies have been formally approved by the Food and Drug Administration for use in pediatric multiple sclerosis, a rare disease. OBJECTIVE:We evaluated the safety, efficacy, and pharmacokinetics of dimethyl fumarate in pediatric patients with multiple sclerosis. METHODS:FOCUS, a phase 2, multicenter s...

journal_title：Pediatric neurology

authors： Alroughani R,Das R,Penner N,Pultz J,Taylor C,Eraly S

更新日期：2018-06-01 00:00:00

abstract：:Chronic injury to the brain from seizure activity is associated with decreased language skills in pediatric patients, as measured on neuropsychological tests for language function and academic achievement. This makes the study of language in patients with epilepsy clinically necessary. Functional magnetic resonance im...

journal_title：Pediatric neurology

authors： Chou N,Serafini S,Muh CR

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Seizures may cause added harm in neonates with hypoxic-ischemic encephalopathy (HIE). Specific recommendations about seizure treatment in this context are lacking. We sought to determine the scope of practice regarding management of non-status epilepticus electrographic-only seizures in this setting. METHOD...

journal_title：Pediatric neurology

authors： McNally MA,Hartman AL

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Although cerebral palsy is reported to have a higher prevalence in low-resource settings, there are few studies describing risk factors for cerebral palsy in these settings. A better understanding of the unique risk factors affecting children with cerebral palsy in low-resource settings could optimize both r...

journal_title：Pediatric neurology

authors： Monokwane B,Johnson A,Gambrah-Sampaney C,Khurana E,Baier J,Baranov E,Westmoreland KD,Mazhani L,Steenhoff AP,Bearden DR

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The identification of a biomarker for sudden unexpected death in epilepsy (SUDEP) has the potential to save lives. Generalized convulsive seizures and postictal generalized suppression on electroencephalography (EEG) most often precede sudden unexpected death in epilepsy (SUDEP) and are potential biomarkers....

journal_title：Pediatric neurology

authors： Okanari K,Otsubo H,Kouzmitcheva E,Rangrej J,Baba S,Ochi A,Okanishi T,Homma Y,Nita DA,Donner EJ

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Throughout the Middle Ages, most representations of the brain amounted to highly schematized ventricles housed within abstract squiggles of neural tissue. The works by the pre-eminent Flemish anatomist Andreas Vesalius in his De Humani Corporis Fabrica (1543) added considerably more accuracy and detail; stil...

journal_title：Pediatric neurology

authors： Sutherland-Foggio H

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:We describe the trends in antiepileptic drug (AED) use in children and adolescents with epilepsy in the United States. METHODS:We undertook a cross-sectional study based on Medicaid Analytic eXtract data set from 26 US states. Children and adolescents aged three to 18 years with at least one year continuous ...

journal_title：Pediatric neurology

authors： Liu X,Carney PR,Bussing R,Segal R,Cottler LB,Winterstein AG

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:We identified a group of patients with ATP1A3 mutations at residue 756 who display a new phenotype, distinct from alternating hemiplegia of childhood, rapid-onset dystonia-parkinsonism, and cerebellar ataxia, areflexia, pes cavus, optic atrophy, sensorineural hearing loss syndromes. METHODS:Four patients wi...

journal_title：Pediatric neurology

authors： Yano ST,Silver K,Young R,DeBrosse SD,Ebel RS,Swoboda KJ,Acsadi G

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Newborns with congenital heart disease have associated brain damage that affects short-and long-term neurodevelopment. Several neuronal biomarkers exist that could predict brain damage. We investigated the pattern of neuron-specific enolase (NSE) and s100B levels after cardiopulmonary bypass surgery in neona...

journal_title：Pediatric neurology

authors： Trakas E,Domnina Y,Panigrahy A,Baust T,Callahan PM,Morell VO,Munoz R,Bell MJ,Sanchez-de-Toledo J

更新日期：2017-07-01 00:00:00