abstract：OBJECTIVE:The efficacy of argon plasma coagulation (APC) on gastric antral vascular ectasia (GAVE) may be impaired over time and depends greatly on the application settings. Endoscopic band ligation (EBL) may be an alternative, but study on its efficacy is limited. This study aimed to evaluate and compare the clinical ...

journal_title：Journal of digestive diseases

authors： Fábián A,Bor R,Szabó E,Kardos V,Bálint A,Farkas K,Milassin Á,Rutka M,Szántó K,Molnár T,Szűcs M,Lőrinczy K,Orbán-Szilágyi Á,Gyökeres T,Gyimesi G,Szepes A,Kovács V,Rácz I,Szepes Z

更新日期：2021-01-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is now the most common etiology of chronic liver disease threatening global public health. However, the name "NAFLD" is no longer appropriate with the change of time. Recently, a new term, "metabolic dysfunction-associated fatty liver disease" has been proposed by an internati...

journal_title：Journal of digestive diseases

authors： Lin SZ,Chen YW,Fan JG

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Early diagnosis of colitis-associated cancer and dysplasia through surveillance endoscopy is vital for patients with ulcerative colitis (UC). This study aimed to evaluate the efficacy of autofluorescence endoscopy (AFE) using 5-aminolevulinic acid (ALA) and to investigate the fluorescence signal localization ...

journal_title：Journal of digestive diseases

authors： Kato T,Iwasaki T,Arihiro S,Saruta M

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the differences in symptoms, high-resolution manometry (HRM) characteristics, and the efficacy of peroral endoscopic myotomy (POEM) regarding patients' sex in achalasia. METHODS:All patients diagnosed with achalasia by HRM who underwent POEM and were followed up for more than 6 months we...

journal_title：Journal of digestive diseases

authors： Xu Y,Ye BX,Wang Y,Bao Y,Chen XS,Tang YR,Lin L,Jiang LQ

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:Transarterial chemoembolization (TACE) is the treatment modality for intermediate, or Barcelona Clinic Liver Cancer stage B, hepatocellular carcinoma (HCC), but its beneficial effect on outcomes is still unsatisfactory. This study aimed to assess the outcomes of combined TACE and sorafenib for patients with i...

journal_title：Journal of digestive diseases

authors： Lee SW,Tung CF,Peng YC,Lien HC,Chang CS

更新日期：2020-08-01 00:00:00

abstract：:Fibroblast infiltration and collagen deposition result in structural changes in the bowel wall, and lead to strictures in intestinal inflammatory disease. While strictures can also occur in other contexts, such as malignancy, this review focuses on the surgical treatment of stricture secondary to inflammatory bowel di...

journal_title：Journal of digestive diseases

authors： Mohan HM,Coffey JC

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:To evaluate whether patients with malignant biliary obstruction (MBO) benefit from balloon dilation before the placement of a self-expanding metal stent (SEMS) for palliative biliary drainage. METHODS:Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with SEMS placement for pa...

journal_title：Journal of digestive diseases

authors： Shen ZY,Wang JJ,Lu LG,Wan R,Wan XJ,Cai XB

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To explore the prevalence of and risk factors for gallstone disease in Shanghai, China. METHODS:A population-based cross-sectional study was conducted in Shanghai between 2016 and 2017. Using a three-stage stratified sampling strategy, 4009 participants (1753 men and 2256 women) from 10 districts were enroll...

journal_title：Journal of digestive diseases

authors： Song ST,Shi J,Wang XH,Guo YB,Hu PF,Zhu F,Zeng X,Xie WF

更新日期：2020-04-01 00:00:00

abstract：:Gut microbiota constitute the largest reservoir of the human microbiome and are an abundant and stable ecosystem-based on its diversity, complexity, redundancy, and host interactions This ecosystem is indispensable for human development and health. The integrity of the intestinal mucosal barrier depends on its interac...

journal_title：Journal of digestive diseases

authors： Guo XY,Liu XJ,Hao JY

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:Data on the association between the antioxidant capacity of a diet and the risk of ulcerative colitis (UC) are scarce. This study aimed to assess whether a relationship exists between dietary total antioxidant capacity (TAC) and the odds of UC in Iranian adults. METHODS:In this case-control study, patients w...

journal_title：Journal of digestive diseases

authors： Rahmani J,Kord-Varkaneh H,Ryan PM,Rashvand S,Clark C,Day AS,Hekmatdoost A

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:We conducted a randomized trial aiming at improving patients' informed consent for undergoing endoscopic retrograde cholangiopancreatography (ERCP) in clinical care by comparing the efficacy of an additional educational video to written informed consent with that of written informed consent alone. METHODS:Th...

journal_title：Journal of digestive diseases

authors： Xia T,Zhu YB,Zeng YB,Chen C,Wang SL,Zhao SB,Su XJ,Wang D,Yao J,Li ZS,Bai Y

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To investigate the clinical features of Clostridium difficile infection (CDI) in hospitalized patients with inflammatory bowel disease (IBD) and to analyze the impact of CDI on IBD. METHODS:A prospective study on patients newly diagnosed with IBD was conducted at the IBD center at Sir Run Run Shaw Hospital f...

journal_title：Journal of digestive diseases

authors： Chen XL,Deng J,Chen X,Wan SS,Wang Y,Cao Q

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate the clinical features, precipitating factors, bowel habits, bothersome symptoms and treatment strategies of individuals in China with self-reported constipation. METHODS:An internet-based survey was conducted in China. The participants had self-reported chronic constipation (≥1 sympto...

journal_title：Journal of digestive diseases

authors： Song J,Bai T,Zhang L,Hou XH

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVES:Peptest is a new non-invasive reflux diagnostic test based on lateral flow technology that containing two highly specific human pepsin monoclonal antibodies for detecting pepsin, a biomarker for reflux disease. The primary aim of this multicenter clinical study was to validate the efficacy of Peptest in pati...

journal_title：Journal of digestive diseases

authors： Wang YF,Yang CQ,Chen YX,Cao AP,Yu XF,Yu Y,Zhang ZY,Shen XZ,Liu F,Zhong L,Wang YX,Liu ZJ,Shi YH,Zhong J,Li JN,Lan Y,Lenham RK,Woodcock AD,Dettmar PW,Fang JY

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) is a valuable device to diagnose and determine the malignant potential of gastrointestinal stromal tumors (GIST) as early as possible when making clinical therapeutic decisions. This study aimed to estimate the ability of CH-EUS to discriminate be...

journal_title：Journal of digestive diseases

authors： Tang JY,Tao KG,Zhang LY,Wu KM,Shi J,Zeng X,Lin Y

更新日期：2019-03-01 00:00:00

abstract：:Drug-induced liver injury (DILI), which is caused by drugs and herbal or dietary supplements, remains a serious concern for drug developers, regulators, and clinicians; however, serum biomarkers utilized to detect and monitor DILI have not changed in decades and have limitations. Data-driven mathematical modeling that...

journal_title：Journal of digestive diseases

authors： Church RJ,Watkins PB

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To investigate retrospectively the efficacy of steroids in patients with acute-on-chronic liver failure (ACLF) precipitated by hepatitis B. METHODS:Patients with ACLF precipitated by hepatitis B were included and categorized according to treatment modalities (steroid vs. control). Survival and clinical chara...

journal_title：Journal of digestive diseases

authors： Huang C,Yu KK,Zheng JM,Li N

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:Methotrexate (MTX) can be used as an alternative for patients with Crohn's disease (CD) who are intolerant of thiopurine. This retrospective study aimed to provide some clues about MTX treatment in Chinese patients with CD. METHODS:Medical records of 27 adult patients with CD who were treated with MTX betwee...

journal_title：Journal of digestive diseases

authors： Wang TR,Qiao YQ,Zou DW,Ran ZH

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term outcomes of complete common bile duct (CBD) stone removal and biliary stenting in elderly patients (≥85 years) with CBD stones. METHODS:We retrospectively examined 65 patients who underwent complete CBD stone removal (the duct clearance group) and 40 patients who underwent biliary s...

journal_title：Journal of digestive diseases

authors： Akazawa Y,Ohtani M,Nosaka T,Saito Y,Takahashi K,Naito T,Ofuji K,Matsuda H,Hiramatsu K,Nemoto T,Nakamoto Y

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:With an age-standardized incidence rate of 2 per 100 000, esophageal cancer is not common among Malaysians, but they are nevertheless important due to its poor prognosis. The study is to clarify whether the human papillomavirus (HPV) is associated with esophageal cancer in Malaysians as there has been no repo...

journal_title：Journal of digestive diseases

authors： Cheah PL,Koh CC,Khang TF,Goh KL,Lau PC,Chin KF,Teoh KH,Toh YF,Looi LM

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:The histone methylation and acetylation pathway genes regulate cell growth and survival. Aberrations in this pathway are implicated in a variety of cancers. This study aimed to identify germline genetic variants in histone methylation and acetylation pathway genes that may contribute to risk in eight types o...

journal_title：Journal of digestive diseases

authors： Fu LN,Tan J,Chen YX,Fang JY

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:The microenvironment of tumors constitutes a unique niche that promotes cancer metastasis and resistance. Two remarkable characteristics of this microenvironment are hypoxia and inflammation. Interleukin-1α (IL-1α), an important inflammatory factor, is frequently upregulated in a variety of cancers. This stud...

journal_title：Journal of digestive diseases

authors： Xuan Y,Wang YN

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:Given the rarity of the disease, the post-resection clinical course of localized pancreatic acinar cell carcinoma (ACC) is largely unknown. Therefore, we aimed to analyze the outcomes of patients with localized pancreatic ACC who underwent curative surgical resection. METHODS:We retrospectively analyzed the ...

journal_title：Journal of digestive diseases

authors： Seo S,Yoo C,Kim KP,Ryoo BY,Chang HM,Hong SM,Lee JH,Song KB,Hwang DW,Kim KH,Hwang S,Kim SC

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:To investigate whether sending a family history questionnaire to patients prior to undergoing colonoscopy results in an increased availability of family history and better genetic counseling. METHODS:A questionnaire was mailed to patients before they underwent outpatient colonoscopy at a university hospital...

journal_title：Journal of digestive diseases

authors： Kessels K,Eisinger JD,Letteboer TG,Offerhaus GJA,Siersema PD,Moons LMG

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To analyze the prognostic effect of E-cadherin expression, the growth pattern of the tumor and the regression grade in a rectal cancer cohort treated with neoadjuvant radiochemotherapy (RCT). METHODS:A total of 223 patients with rectal cancer treated with neoadjuvant RCT followed by surgery were included. Al...

journal_title：Journal of digestive diseases

authors： Jessberger J,Erlenbach-Wünsch K,Posselt R,Haderlein M,Agaimy A,Fietkau R,Hartmann A,Distel L

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVES:Preoperative biliary drainage (PBD) can relieve symptoms of cholestasis, but carries risk of procedural complications. Metal stents have wider lumens and longer patency, although plastic stents (PS) remain in use. We reviewed the outcomes after PBD in patients with cholestasis. METHODS:Patients with symptom...

journal_title：Journal of digestive diseases

authors： Ma MX,Chin MWS,Jennings M,Siah C,Edmunds S

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:MicroRNA-1254 (miR-1254) has not been studied in colorectal cancer (CRC) to date. This study aimed to investigate the inhibitory mechanism of miR-1254 in CRC tumorigenesis. METHODS:MiR-1254 expression was examined using real-time polymerase chain reaction in CRC and adjacent non-tumorous tissues. The correla...

journal_title：Journal of digestive diseases

authors： Chu YM,Peng HX,Xu Y,Yang DM,Zhou FL,Li J,Kuai R,Lin Y

更新日期：2017-03-01 00:00:00

abstract：:The incidence and prevalence of inflammatory bowel disease (IBD) show considerable variation over time and across geographical regions. The first studies on the epidemiology of IBD were mainly from traditionally high-incidence areas, such as North America, and northern and western Europe. In the last two decades, more...

journal_title：Journal of digestive diseases

authors： Vegh Z,Kurti Z,Lakatos PL

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the features of microRNA (miRNA) at different fibrotic stages in patients with hepatitis B virus (HBV)-related liver fibrosis. METHODS:Liver tissues were collected from 40 chronic hepatitis B (CHB) patients at fibrotic stages S0-4. Microarrays of miRNAs and genomic informatics analysis w...

journal_title：Journal of digestive diseases

authors： Chen R,Wu JC,Liu T,Qu Y,Lu LG,Xu MY

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence and potential risk factors of latent tuberculosis infection (LTBI) in Chinese patients with inflammatory bowel disease (IBD) and to evaluate the role of chest computed tomography (CT) in the screening of LTBI. METHODS:A single-center retrospective study was conducted and all IBD pat...

journal_title：Journal of digestive diseases

authors： Song DJ,Tong JL,Peng JC,Cai CW,Xu XT,Zhu MM,Ran ZH,Zheng Q

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To carry out a comprehensive study on gastrointestinal symptoms, motility and autonomic neuropathy in chronic alcoholics before and one year after abstinence. METHODS:Dyspeptic symptoms (questionnaires), fasting and postprandial gallbladder and gastric motility (ultrasonography), oro-cecal transit time (lact...

journal_title：Journal of digestive diseases

authors： Di Ciaula A,Grattagliano I,Portincasa P

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To investigate the alterations and functions of intrahepatic B (IHB) cells in non-alcoholic fatty liver disease (NAFLD) model induced by high-fat diet (HFD). METHODS:C57BL/6 J mice were fed with HFD for 16 weeks to induce NAFLD. Flow cytometry was used to analyze lymphocytes from liver, spleen and peripheral...

journal_title：Journal of digestive diseases

authors： Zhang F,Jiang WW,Li X,Qiu XY,Wu Z,Chi YJ,Cong X,Liu YL

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:Whether minocycline can replace tetracycline in Helicobacter pylori (H. pylori) eradication remains unclear. The aim of this study was to determine the efficacy, safety, patient compliance and risk factors of a combination regimen of esomeprazole, minocycline, metronidazole and bismuth (EMMB) for H. pylori er...

journal_title：Journal of digestive diseases

authors： Song ZQ,Zhou LY

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:This study aimed to systematically assess the relevant risk factors of positive lateral margin (LM) after en bloc resection of early gastric adenocarcinoma. METHODS:A total of 242 patients who had undergone endoscopic submucosal dissection (ESD) due to early gastric lesions from January 2009 to March 2015 we...

journal_title：Journal of digestive diseases

authors： Fu QY,Cui Y,Li XB,Chen P,Chen XY

更新日期：2016-04-01 00:00:00

abstract：:Along with epidemiological changes in tuberculosis (TB) and an increased incidence of Crohn's disease (CD), the differential diagnosis of intestinal TB (ITB) and CD is of vital importance and has become a clinical challenge because treatment based on misdiagnosis may lead to fatal outcomes. In this study, we reviewed ...

journal_title：Journal of digestive diseases

authors： Ma JY,Tong JL,Ran ZH

更新日期：2016-03-01 00:00:00

abstract：:Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is one of the most common medical emergencies in China and worldwide. In 2009, we published the "Guidelines for the diagnosis and treatment of acute non-variceal upper gastrointestinal bleeding" for the patients in China; however, during the past years numer...

journal_title：Journal of digestive diseases

authors： Bai Y,Li ZS

更新日期：2016-02-01 00:00:00

abstract：:Lgr5 marks stem cells in digestive epithelial tissues by lineage tracing, and in vitro ever-expansion of Lgr5 stem cells form organoids, which can be directed to differentiate into functional somatic cells. Organoids derived from gastrointestinal epithelium even recapitulate the morphologic features of their in vivo c...

journal_title：Journal of digestive diseases

authors： Xu AT,Tong JL,Ran ZH

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To explore the role of tagging single nucleotide polymorphisms (tagSNPs) in the adiponectin gene in the natural course of nonalcoholic fatty liver disease (NAFLD). METHODS:The participants were chosen from our previous survey containing 3543 individuals. Finally, a total of 696 participants who had been foll...

journal_title：Journal of digestive diseases

authors： Zhou YJ,Zhang ZS,Nie YQ,Cao J,Cao CY,Li YY

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:MicroRNAs (miRNAs) have recently emerged as novel regulators in liver fibrosis. miR-30c and miR-193 are involved in fibrotic remodeling processes and cancer development, respectively. This study aimed to explore the role of miR-30c and miR-193 in liver fibrosis. METHODS:The regulation of miRNAs in carbon tet...

journal_title：Journal of digestive diseases

authors： Roy S,Benz F,Vargas Cardenas D,Vucur M,Gautheron J,Schneider A,Hellerbrand C,Pottier N,Alder J,Tacke F,Trautwein C,Roderburg C,Luedde T

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The incidence of nonsteroidal anti-inflammatory drugs (NSAIDs)-induced enteropathy is currently increasing. However, the predictors of small bowel bleeding (SBB) associated with NSAIDs are unknown. This study aimed to assess the risk factors of SBB in chronic NSAIDs users. METHODS:We retrospectively compared...

journal_title：Journal of digestive diseases

authors： Cho KM,Park SY,Chung JO,Jun CH,Kim TJ,Son DJ,Kim BS,Park CH,Kim HS,Choi SK,Rew JS

更新日期：2015-09-01 00:00:00