Abstract：
OBJECTIVE:To evaluate whether patients with malignant biliary obstruction (MBO) benefit from balloon dilation before the placement of a self-expanding metal stent (SEMS) for palliative biliary drainage. METHODS:Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with SEMS placement for palliative management of MBO were retrospectively included. Comparative analyses of serum bilirubin levels, post-procedural adverse events, stent patency time, stent dysfunction, and patient survival were performed between the dilation and non-dilation groups. RESULTS:A total of 221 patients underwent palliative endoscopic SEMS implantation for MBO from January 2014 to June 2018. Dilation significantly improved the percentage of serum bilirubin improvement (37.0% vs 14.3%, P = 0.001), with a decreasing trend in the incidence of post-procedural cholangitis (2.5% vs 7.8%, P = 0.075), while the rates of other complications such as pancreatitis and bleeding were not increased. The patency time of SEMS and patient survival did not significantly differ between patients with and without dilation. Patients had endoscopic nasobiliary drainage (ENBD) but not dilation showed similar short-term outcomes as patients underwent dilation but without ENBD. CONCLUSIONS:Dilation with a small-caliber balloon catheter before the placement of SEMS is a safe and effective approach for MBO. Balloon dilation may improve the short-term efficacy of SEMS placement, while long-term outcomes are not obviously affected. The short-term effect of stricture dilation may be achieved by ENBD. Further studies are needed to confirm our results.
journal_name
J Dig Disjournal_title
Journal of digestive diseasesauthors
Shen ZY,Wang JJ,Lu LG,Wan R,Wan XJ,Cai XBdoi
10.1111/1751-2980.12864subject
Has Abstractpub_date
2020-05-01 00:00:00pages
293-300issue
5eissn
1751-2972issn
1751-2980journal_volume
21pub_type
杂志文章abstract：OBJECTIVE:This study aimed to determine the prevalence of and risk factors associated with elevated alanine aminotransferase (ALT) levels among a sample of normal weight, overweight and obese youth from two urban populations in Central Mexico. METHODS:Baseline data from 1262 youth aged 8-19 years who participated in t...
journal_title：Journal of digestive diseases
pub_type： 杂志文章
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abstract：OBJECTIVE:To explore the prevalence of and risk factors for gallstone disease in Shanghai, China. METHODS:A population-based cross-sectional study was conducted in Shanghai between 2016 and 2017. Using a three-stage stratified sampling strategy, 4009 participants (1753 men and 2256 women) from 10 districts were enroll...
journal_title：Journal of digestive diseases
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journal_title：Journal of digestive diseases
pub_type： 杂志文章,实务指引
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12342
更新日期：2016-04-01 00:00:00
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journal_title：Journal of digestive diseases
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doi：10.1111/1751-2980.12605
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pub_type： 杂志文章
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pub_type： 杂志文章,评审
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更新日期：2013-04-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/j.1443-9573.2007.00290.x
更新日期：2007-05-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章,评审
doi：10.1111/j.1751-2980.2008.00334.x
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pub_type： 杂志文章,评审
doi：10.1111/j.1751-2980.2011.00480.x
更新日期：2011-04-01 00:00:00
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pub_type： 杂志文章,meta分析
doi：10.1111/1751-2980.12710
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pub_type： 杂志文章
doi：10.1111/1751-2980.12182
更新日期：2014-11-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/1751-2980.12944
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更新日期：2017-05-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12923
更新日期：2020-09-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12040
更新日期：2013-06-01 00:00:00
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更新日期：2014-01-01 00:00:00
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doi：10.1111/1751-2980.12126
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12922
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/j.1751-2980.2007.00309.x
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pub_type： 杂志文章
doi：10.1111/1751-2980.12086
更新日期：2013-11-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/j.1751-2980.2009.00412.x
更新日期：2010-02-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/j.1751-2980.2008.00346.x
更新日期：2008-11-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12656
更新日期：2018-10-01 00:00:00
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journal_title：Journal of digestive diseases
pub_type： 杂志文章
doi：10.1111/1751-2980.12140
更新日期：2014-06-01 00:00:00
abstract：:Fibroblast infiltration and collagen deposition result in structural changes in the bowel wall, and lead to strictures in intestinal inflammatory disease. While strictures can also occur in other contexts, such as malignancy, this review focuses on the surgical treatment of stricture secondary to inflammatory bowel di...
journal_title：Journal of digestive diseases
pub_type： 杂志文章,评审
doi：10.1111/1751-2980.12880
更新日期：2020-06-01 00:00:00
