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Peritoneal mesothelioma presenting as an acute surgical abdomen due to jejunal perforation.

Abstract：

BACKGROUND:Peritoneal mesothelioma is a rare disease associated with poor prognosis. Acute abdomen as the first presentation is an extremely rare occurrence. We report an exceptional case of a patient who was found to have a jejunal perforation due to infiltration of peritoneal mesothelioma. METHODS:A 62-year-old man was admitted with clinical signs of peritonitis. Computerized tomographic scans showed a mass distal to the ligament of Treitz, thickening of the mesentery and a small amount of ascites. RESULTS:Emergency laparotomy revealed a perforated tumor 15 cm distal to the ligament of Treitz and diffuse peritoneal disease. Segmental small bowel resection and suboptimal cytoreduction were performed. Histopathology and immunohistochemistry showed infiltration of malignant mesothelioma. During the postoperative period pleural mesothelioma was also diagnosed. Despite adjuvant chemotherapy, the patient died of disseminated progressive disease 7 months after surgery. CONCLUSIONS:Peritoneal mesothelioma is a rare malignancy with grim prognosis. Small bowel involvement is a poor prognostic indicator. Our case of a small bowel perforation due to direct infiltration by peritoneal mesothelioma appears to be the first reported in the English literature.

journal_name

J Dig Dis

journal_title

Journal of digestive diseases

authors

Salemis NS,Tsiambas E,Gourgiotis S,Mela A,Karameris A,Tsohataridis E

doi

10.1111/j.1751-2980.2007.00309.x

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

216-21

issue

4

eissn

1751-2972

issn

1751-2980

pii

CDD309

journal_volume

8

pub_type

杂志文章

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