Non-alcoholic fatty liver disease to metabolic dysfunction-associated fatty liver disease: Conceptual changes for clinicians, researchers and patients.

abstract：OBJECTIVE:To investigate the clinicopathological features of columnar-lined esophagus (CLE) in Chinese patients. METHODS:Among 182 consecutive resections of proximal gastric cancer with residual esophageal tissue, 114 were eligible for the study. The maximal lengths of CLE and superficial esophageal glands (SEG) and t...

journal_title：Journal of digestive diseases

authors： Sun Q,Huang Q,Feng AN,Fan XS,Wu HY,Mashimo H,Zhou Q,Chen J,Lauwers GY

更新日期：2013-01-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studies have shown an in...

journal_title：Journal of digestive diseases

authors： Goh K,Xiao SD

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:With an age-standardized incidence rate of 2 per 100 000, esophageal cancer is not common among Malaysians, but they are nevertheless important due to its poor prognosis. The study is to clarify whether the human papillomavirus (HPV) is associated with esophageal cancer in Malaysians as there has been no repo...

journal_title：Journal of digestive diseases

authors： Cheah PL,Koh CC,Khang TF,Goh KL,Lau PC,Chin KF,Teoh KH,Toh YF,Looi LM

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To investigate the expression of peroxisome proliferator-activated receptors (PPAR)gamma and the effects of PPARgamma ligands on cells growth in colorectal cancer (CRC) cell line HT-29, and to explore whether the activation of PPARgamma by its selective ligand can induce apoptosis and the arrest of the cell c...

journal_title：Journal of digestive diseases

authors： Lin MS,Chen WC,Bai X,Wang YD

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to systematically assess the relevant risk factors of positive lateral margin (LM) after en bloc resection of early gastric adenocarcinoma. METHODS:A total of 242 patients who had undergone endoscopic submucosal dissection (ESD) due to early gastric lesions from January 2009 to March 2015 we...

journal_title：Journal of digestive diseases

authors： Fu QY,Cui Y,Li XB,Chen P,Chen XY

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:MicroRNA-1254 (miR-1254) has not been studied in colorectal cancer (CRC) to date. This study aimed to investigate the inhibitory mechanism of miR-1254 in CRC tumorigenesis. METHODS:MiR-1254 expression was examined using real-time polymerase chain reaction in CRC and adjacent non-tumorous tissues. The correla...

journal_title：Journal of digestive diseases

authors： Chu YM,Peng HX,Xu Y,Yang DM,Zhou FL,Li J,Kuai R,Lin Y

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the role of insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) in the development of hepatic fibrogenesis in experimental disease models and human liver samples. METHODS:Cellular distribution patterns of IGFBP-rP1 were assessed by immunohistochem...

journal_title：Journal of digestive diseases

authors： Guo XH,Liu LX,Zhang HY,Zhang QQ,Li Y,Tian XX,Qiu ZH

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To summarize the clinical and spiral computed tomography (CT) features of undifferentiated embryonic liver sarcoma (UELS) in adults. METHODS:Clinical and CT findings of four adult patients with pathology-approved UELS were retrospectively analyzed with a literature review. All patients were examined using a ...

journal_title：Journal of digestive diseases

authors： Yang L,Chen LB,Xiao J,Han P

更新日期：2009-11-01 00:00:00

abstract：OBJECTIVE:To investigate whether the ultrastructure and hydrogen potassium adenosine triphosphate (H+ /K+ ATPase) expression of human parietal cells were associated with aging. METHODS:In all, 50 participants who underwent gastroscopy due to dyspepsia were divided into two age groups, with 19 in the younger group (YG,...

journal_title：Journal of digestive diseases

authors： Zhang W,Zheng SB,Zhuang Y,Xiang P,Xiao L,Li B,Ji da N,Xia SJ,Yu Z,Shi DY

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to analyze the incidence and risk factors of de novo hepatitis B virus (HBV) infection from hepatitis B core antibody (anti-HBc)-positive donors in pediatric living donor liver transplantation (LDLT). METHODS:We retrospectively analyzed 46 recipients without pre-liver transplantatio...

journal_title：Journal of digestive diseases

authors： Xi ZF,Xia Q,Zhang JJ,Chen XS,Han LZ,Zhu JJ,Wang SY,Qiu DK

更新日期：2013-08-01 00:00:00

abstract：:Along with epidemiological changes in tuberculosis (TB) and an increased incidence of Crohn's disease (CD), the differential diagnosis of intestinal TB (ITB) and CD is of vital importance and has become a clinical challenge because treatment based on misdiagnosis may lead to fatal outcomes. In this study, we reviewed ...

journal_title：Journal of digestive diseases

authors： Ma JY,Tong JL,Ran ZH

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:We aimed to determine the effect of antithrombotics on in-hospital mortality and morbidity in patients with peptic ulcer disease-related upper gastrointestinal bleeding (PUD-related UGIB). METHODS:The study cohort was retrospectively selected from a tertiary center database of patients with PUD-related UGIB,...

journal_title：Journal of digestive diseases

authors： Abu Daya H,Eloubeidi M,Tamim H,Halawi H,Malli AH,Rockey DC,Barada K

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Probiotics are increasingly advocated in the management of various gastrointestinal disorders. The aim of this study was to investigate the current attitudes and prescribing practices of surgeons and gastroenterologists for probiotics in the treatment of gastrointestinal disorders. METHODS:A questionnaire wa...

journal_title：Journal of digestive diseases

authors： Cordina C,Shaikh I,Shrestha S,Camilleri-Brennan J

更新日期：2011-12-01 00:00:00

abstract：:Barrett's esophagus (BE)-related esophageal adenocarcinoma (EAC) has shown the fastest rise in incidence in Western countries; however, research data on BE-related diseases from China are inconclusive. We aimed to review and analyze the published results on these diseases in China. We searched PubMed and Chinese medic...

journal_title：Journal of digestive diseases

authors： Huang Q,Fang DC,Yu CG,Zhang J,Chen MH

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To explore the features and clinical significance of serum pepsinogen (PG) assay in a follow-up study on a high-risk gastric cancer (GC) population. METHODS:A total of 444 participants from a high-risk area of GC in north China were enrolled in this follow-up study from April 1997 to December 1999. Serum PG ...

journal_title：Journal of digestive diseases

authors： Sun LP,Gong YH,Wang L,Gong W,Yuan Y

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:MicroRNAs (miRNAs) have recently emerged as novel regulators in liver fibrosis. miR-30c and miR-193 are involved in fibrotic remodeling processes and cancer development, respectively. This study aimed to explore the role of miR-30c and miR-193 in liver fibrosis. METHODS:The regulation of miRNAs in carbon tet...

journal_title：Journal of digestive diseases

authors： Roy S,Benz F,Vargas Cardenas D,Vucur M,Gautheron J,Schneider A,Hellerbrand C,Pottier N,Alder J,Tacke F,Trautwein C,Roderburg C,Luedde T

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:The capacity of fundoplication to prevent esophageal adenocarcinoma is controversial. Development of cancer is associated with proliferation and anti-apoptosis, for which little data exist as to their response to fundoplication. Therefore, we wanted to clarify the effect of fundoplication on the magnitude of ...

journal_title：Journal of digestive diseases

authors： Rantanen T,Oksala N,Honkanen T,Räsänen J,Sihvo E,Mattila J,Paimela H,Paavonen T,Salo J

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term outcomes of complete common bile duct (CBD) stone removal and biliary stenting in elderly patients (≥85 years) with CBD stones. METHODS:We retrospectively examined 65 patients who underwent complete CBD stone removal (the duct clearance group) and 40 patients who underwent biliary s...

journal_title：Journal of digestive diseases

authors： Akazawa Y,Ohtani M,Nosaka T,Saito Y,Takahashi K,Naito T,Ofuji K,Matsuda H,Hiramatsu K,Nemoto T,Nakamoto Y

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:We aimed to identify the features of microRNA (miRNA) at different fibrotic stages in patients with hepatitis B virus (HBV)-related liver fibrosis. METHODS:Liver tissues were collected from 40 chronic hepatitis B (CHB) patients at fibrotic stages S0-4. Microarrays of miRNAs and genomic informatics analysis w...

journal_title：Journal of digestive diseases

authors： Chen R,Wu JC,Liu T,Qu Y,Lu LG,Xu MY

更新日期：2017-02-01 00:00:00

abstract：:Aldehyde dehydrogenase (ALDH2) and alcohol dehydrogenase (ADH) gene polymorphisms associating with enhanced acetaldehyde exposure and markedly increased cancer risk in alcohol drinkers provide undisputable evidence for acetaldehyde being a local carcinogen not only in esophageal but also in gastric cancer. Accordingly...

journal_title：Journal of digestive diseases

authors： Salaspuro M

更新日期：2011-04-01 00:00:00

abstract：:Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first recognized histologic change is active chronic inflammation, which may persist as such: non-atrophic chronic gastritis (no gland loss), or advance to multifocal atrophic gastritis (MAG), the first real step in the precancerous casca...

journal_title：Journal of digestive diseases

authors： Correa P,Piazuelo MB

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Nonalcoholic fatty liver disease (NAFLD) is a common chronic liver disease, the natural course of which has not been well documented. This study aimed to perform a prospective cohort study to investigate NAFLD in a Chinese population. METHODS:Using our previous epidemiological survey, 3543 patients were foll...

journal_title：Journal of digestive diseases

authors： Zhou YJ,Li YY,Nie YQ,Huang CM,Cao CY

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the prevalence of and risk factors associated with elevated alanine aminotransferase (ALT) levels among a sample of normal weight, overweight and obese youth from two urban populations in Central Mexico. METHODS:Baseline data from 1262 youth aged 8-19 years who participated in t...

journal_title：Journal of digestive diseases

authors： Purcell M,Flores YN,Zhang ZF,Denova-Gutiérrez E,Salmeron J

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Peritoneal mesothelioma is a rare disease associated with poor prognosis. Acute abdomen as the first presentation is an extremely rare occurrence. We report an exceptional case of a patient who was found to have a jejunal perforation due to infiltration of peritoneal mesothelioma. METHODS:A 62-year-old man ...

journal_title：Journal of digestive diseases

authors： Salemis NS,Tsiambas E,Gourgiotis S,Mela A,Karameris A,Tsohataridis E

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Our aim was to investigate the expression of cytotoxic T lymphocyte-associated molecule 4 (CTLA-4) in ulcerative colitis (UC) and to evaluate the effect of CTLA-4 gene -1661A/G polymorphism on CTLA-4 expression and transcription. METHODS:A total of 20 UC patients and 22 healthy controls matched by age and se...

journal_title：Journal of digestive diseases

authors： Jiang T,Ge LQ,Chen ZT,Li C,Zhou F,Luo Y,Xia B

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:Systematic reports on acute upper gastrointestinal bleeding in children/adolescents are scanty. The aim of this study is to analyze its presentation, pathology and outcome in Hong Kong. METHODS:A retrospective review of the hospital database for admissions up to the age of 18 years with signs of acute upper ...

journal_title：Journal of digestive diseases

authors： Houben CH,Chiu PW,Lau JY,Lee KH,Ng EK,Tam YH,Yeung CK

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the efficacy of fluorescence spectroscopy of gastric juice for early gastric cancer (EGC) screening. METHODS:Gastric juice was collected from 101 participants who underwent endoscopy in the Outpatient Endoscopy Center of Peking University Third Hospital. The participants were ...

journal_title：Journal of digestive diseases

authors： Deng K,Zhou LY,Lin SR,Li Y,Chen M,Geng QM,Li YW

更新日期：2013-06-01 00:00:00

abstract：:The incidence of early esophageal adenocarcinoma has been increasing significantly in recent decades. Prognosis depends greatly on the choice of treatment. Early cancers can be treated by endoscopic resection, whereas advanced carcinomas have to be sent for surgery. Esophageal resection is associated with high periope...

journal_title：Journal of digestive diseases

authors： Knabe M,May A,Ell C

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:Ursodeoxycholic acid (UDCA) is widely used to treat chronic liver diseases, and its cytoprotective effect on normal hepatocytes has been shown. This study aimed to investigate the apoptotic effects of UDCA on hepatocellular carcinoma (HCC) cells and the underlying molecular events in vitro. METHODS:HCC cells...

journal_title：Journal of digestive diseases

authors： Zhu L,Shan LJ,Liu YJ,Chen D,Xiao XG,Li Y

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Data on the association between the antioxidant capacity of a diet and the risk of ulcerative colitis (UC) are scarce. This study aimed to assess whether a relationship exists between dietary total antioxidant capacity (TAC) and the odds of UC in Iranian adults. METHODS:In this case-control study, patients w...

journal_title：Journal of digestive diseases

authors： Rahmani J,Kord-Varkaneh H,Ryan PM,Rashvand S,Clark C,Day AS,Hekmatdoost A

更新日期：2019-12-01 00:00:00