Abstract:
OBJECTIVE:To explore the prevalence of and risk factors for gallstone disease in Shanghai, China. METHODS:A population-based cross-sectional study was conducted in Shanghai between 2016 and 2017. Using a three-stage stratified sampling strategy, 4009 participants (1753 men and 2256 women) from 10 districts were enrolled. RESULTS:The overall prevalence of gallstones was 6.83% (6.22% for men vs 7.31% for women, P = 0.173). According to the multivariate analysis, individuals aged ≥40 years (odds ratio [OR] 3.058, 95% confidence interval [CI] 2.110-4.433, P < 0.001), hypertension (OR 1.479, 95% CI 1.076-2.034, P = 0.016), thyroid disease (OR 1.409, 95% CI 1.029-1.928, P = 0.032), a family history of gallstones (OR 2.234, 95% CI 1.362-3.662, P = 0.001) and a waist-to-height ratio ≥0.5 (OR 1.656, 95% CI 1.197-2.292, P = 0.002) had an increased risk of developing gallstones. The risk of gallstone disease was 2.232 (95% CI 1.167-4.268, P = 0.015) times higher in individuals with elevated C4 levels than in those with normal C4 levels. Diabetes (OR 4.144, 95% CI 1.171-14.671, P = 0.028) was a risk factor for the formation of gallstones with diameters ≥1 cm, and men were more susceptible to develop multiple stones (OR 2.356, 95% CI 1.321-4.200, P = 0.004). CONCLUSION:Individuals aged ≥40 years, with a history of hypertension and familial gallstones, a high waist-to-height ratio, thyroid disease and high C4 levels were related to an increased risk of gallstone disease.
journal_name
J Dig Disjournal_title
Journal of digestive diseasesauthors
Song ST,Shi J,Wang XH,Guo YB,Hu PF,Zhu F,Zeng X,Xie WFdoi
10.1111/1751-2980.12857subject
Has Abstractpub_date
2020-04-01 00:00:00pages
237-245issue
4eissn
1751-2972issn
1751-2980journal_volume
21pub_type
杂志文章abstract:OBJECTIVE:We aimed to identify the features of microRNA (miRNA) at different fibrotic stages in patients with hepatitis B virus (HBV)-related liver fibrosis. METHODS:Liver tissues were collected from 40 chronic hepatitis B (CHB) patients at fibrotic stages S0-4. Microarrays of miRNAs and genomic informatics analysis w...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12007
更新日期:2013-01-01 00:00:00
abstract::The incidence of early esophageal adenocarcinoma has been increasing significantly in recent decades. Prognosis depends greatly on the choice of treatment. Early cancers can be treated by endoscopic resection, whereas advanced carcinomas have to be sent for surgery. Esophageal resection is associated with high periope...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
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更新日期:2015-07-01 00:00:00
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journal_title:Journal of digestive diseases
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12605
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
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journal_title:Journal of digestive diseases
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更新日期:2008-02-01 00:00:00
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更新日期:2013-09-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2011.00531.x
更新日期:2011-10-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/1751-2980.12449
更新日期:2017-02-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
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journal_title:Journal of digestive diseases
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更新日期:2013-11-01 00:00:00
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journal_title:Journal of digestive diseases
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更新日期:2011-06-01 00:00:00
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更新日期:2015-09-01 00:00:00
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更新日期:2017-03-01 00:00:00
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journal_title:Journal of digestive diseases
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更新日期:2007-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/1751-2980.12415
更新日期:2016-11-01 00:00:00