Abstract:
OBJECTIVE:The aim of our study was to document our 6-year experiences in identifying the clinical characteristics, laboratory findings, risk factors and the outcomes of patients with ischemic colitis (IC) in a community hospital setting. METHODS:The medical records of patients who were diagnosed with IC from 2007 to 2013 in two community hospitals were retrospectively reviewed. Their clinical characteristics, laboratory results, radiological, endoscopic and histological evidence, anatomic location of the lesion, comorbidities, concomitant use of drugs, and so on, were collected. RESULTS:A total of 118 patients with IC was identified, most were elderly individuals with a female predominance. The most common symptoms were abdominal pain, rectal bleeding and diarrhea. Hypertension, hyperlipidemia, coronary artery disease and diabetes mellitus were the most common comorbidities. Erythema, edema and erosions/ulcerations were the most common endoscopic findings. Left colon was the most affected location of lesion (84.8%), and there was one case of pancolitis. The descending colon was the most common affected segment, while rectum was the least affected segment. Severe IC occurred in 12.7% of the patients. Death within 30 days from the diagnosis of the disease occurred in 4.2%. CONCLUSIONS:IC is majorly occurred in elderly with a female predominance. Cardiovascular disease and its associated risk factors are the most common comorbidities. Left colon is the most affected location of the disease and the overall mortality rate was 4.2%. Physicians should make every effort to identify these patients, especially those with high risks.
journal_name
J Dig Disjournal_title
Journal of digestive diseasesauthors
Sherid M,Sifuentes H,Samo S,Sulaiman S,Husein H,Tupper R,Sethuraman SN,Spurr C,Vainder JA,Sridhar Sdoi
10.1111/1751-2980.12182subject
Has Abstractpub_date
2014-11-01 00:00:00pages
606-13issue
11eissn
1751-2972issn
1751-2980journal_volume
15pub_type
杂志文章abstract:OBJECTIVE:The monocyte chemoattractant protein-1 (MCP-1) -A2518G gene polymorphism has been found to be involved in the susceptibility to inflammatory bowel disease (IBD); however, the results of existing studies are controversial. The aim of this meta-analysis was to assess the relationship between the MCP-1 -A2518G p...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1111/1751-2980.12232
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the effects and safety of different doses of ilaprazole on healthy volunteers without a Helicobacter pylori infection. METHODS:A total of 12 healthy Chinese volunteers were enrolled and divided into four groups randomly, with a 5-day treatment of oral ilaprazole 5mg, 10m...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1751-2980.2011.00557.x
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:It is known that the vacuolating cytotoxin (VacA) could induce apoptosis. However, the mechanism remained to be elucidated. The aim of this study is to investigate the role of Bcl family of proteins (Bcl-2 and Bax) and the mitochondrial voltage-dependent anion channel (VDAC) in VacA-induced apoptosis of AGS c...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2009.00412.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:Our aim was to investigate the expression of cytotoxic T lymphocyte-associated molecule 4 (CTLA-4) in ulcerative colitis (UC) and to evaluate the effect of CTLA-4 gene -1661A/G polymorphism on CTLA-4 expression and transcription. METHODS:A total of 20 UC patients and 22 healthy controls matched by age and se...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2010.00462.x
更新日期:2010-12-01 00:00:00
abstract::Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studies have shown an in...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1751-2980.2008.00355.x
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:To evaluate whether patients with malignant biliary obstruction (MBO) benefit from balloon dilation before the placement of a self-expanding metal stent (SEMS) for palliative biliary drainage. METHODS:Consecutive patients who underwent endoscopic retrograde cholangiopancreatography with SEMS placement for pa...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12864
更新日期:2020-05-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12126
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To summarize the clinical and spiral computed tomography (CT) features of undifferentiated embryonic liver sarcoma (UELS) in adults. METHODS:Clinical and CT findings of four adult patients with pathology-approved UELS were retrospectively analyzed with a literature review. All patients were examined using a ...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2009.00400.x
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:Systematic reports on acute upper gastrointestinal bleeding in children/adolescents are scanty. The aim of this study is to analyze its presentation, pathology and outcome in Hong Kong. METHODS:A retrospective review of the hospital database for admissions up to the age of 18 years with signs of acute upper ...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2008.00346.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the prevalence of colorectal neoplasms in patients coronary artery disease (CAD) with or without a family history of colorectal cancer (CRC). METHODS:In this cross-sectional study, individuals with suspected CAD in the absence of cancer-related symptoms underwent coro...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12243
更新日期:2015-05-01 00:00:00
abstract::Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first recognized histologic change is active chronic inflammation, which may persist as such: non-atrophic chronic gastritis (no gland loss), or advance to multifocal atrophic gastritis (MAG), the first real step in the precancerous casca...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2011.00550.x
更新日期:2012-01-01 00:00:00
abstract:OBJECTIVE:Transarterial chemoembolization (TACE) is the treatment modality for intermediate, or Barcelona Clinic Liver Cancer stage B, hepatocellular carcinoma (HCC), but its beneficial effect on outcomes is still unsatisfactory. This study aimed to assess the outcomes of combined TACE and sorafenib for patients with i...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12911
更新日期:2020-08-01 00:00:00
abstract::Gut microbiota constitute the largest reservoir of the human microbiome and are an abundant and stable ecosystem-based on its diversity, complexity, redundancy, and host interactions This ecosystem is indispensable for human development and health. The integrity of the intestinal mucosal barrier depends on its interac...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/1751-2980.12849
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to investigate the frequency and factors involved in the terminal ileum intubation of patients with chronic, non-bloody diarrhea and to compare diagnostic yields of colonoscopy and ileocolonoscopy. METHODS:The medical records of 945 patients undergoing colonoscopy for chronic, non...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12082
更新日期:2013-10-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12958
更新日期:2021-01-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2011.00534.x
更新日期:2011-12-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12491
更新日期:2017-06-01 00:00:00
abstract::Gastric cancer (GC) is one of the inflammation-associated cancers. Helicobacter pylori is now thought to be responsible for more than 95% of all GCs, and its development is associated with at least four mechanisms that lead to genetic instability of the gastric mucosa. The risk of developing GC can be predicted by ass...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/1751-2980.12105
更新日期:2014-01-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12362
更新日期:2016-07-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1443-9573.2007.00321.x
更新日期:2008-02-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12053
更新日期:2013-06-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2011.00508.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:With an age-standardized incidence rate of 2 per 100 000, esophageal cancer is not common among Malaysians, but they are nevertheless important due to its poor prognosis. The study is to clarify whether the human papillomavirus (HPV) is associated with esophageal cancer in Malaysians as there has been no repo...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12605
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:To explore the role of tagging single nucleotide polymorphisms (tagSNPs) in the adiponectin gene in the natural course of nonalcoholic fatty liver disease (NAFLD). METHODS:The participants were chosen from our previous survey containing 3543 individuals. Finally, a total of 696 participants who had been foll...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12288
更新日期:2015-10-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章,随机对照试验
doi:10.1111/1751-2980.12824
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVES:Peptest is a new non-invasive reflux diagnostic test based on lateral flow technology that containing two highly specific human pepsin monoclonal antibodies for detecting pepsin, a biomarker for reflux disease. The primary aim of this multicenter clinical study was to validate the efficacy of Peptest in pati...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,多中心研究
doi:10.1111/1751-2980.12783
更新日期:2019-06-01 00:00:00
abstract::Barrett's esophagus (BE)-related esophageal adenocarcinoma (EAC) has shown the fastest rise in incidence in Western countries; however, research data on BE-related diseases from China are inconclusive. We aimed to review and analyze the published results on these diseases in China. We searched PubMed and Chinese medic...
journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1751-2980.2011.00535.x
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:The incidence of nonsteroidal anti-inflammatory drugs (NSAIDs)-induced enteropathy is currently increasing. However, the predictors of small bowel bleeding (SBB) associated with NSAIDs are unknown. This study aimed to assess the risk factors of SBB in chronic NSAIDs users. METHODS:We retrospectively compared...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12269
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:Non-steroidal anti-inflammatory drugs (NSAID) induce gastroduodenal mucosal injury and are metabolized by cytochrome P450 2C9 (CYP2C9). It is postulated that CYP2C9 genotype is associated with NSAID-induced gastropathy. This study aims to determine whether individuals with a CYP2C9 allele mutation are suscept...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2008.00326.x
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To investigate the expression of peroxisome proliferator-activated receptors (PPAR)gamma and the effects of PPARgamma ligands on cells growth in colorectal cancer (CRC) cell line HT-29, and to explore whether the activation of PPARgamma by its selective ligand can induce apoptosis and the arrest of the cell c...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1443-9573.2007.00290.x
更新日期:2007-05-01 00:00:00