Abstract:
:Inflammatory bowel disease (IBD) has long been considered a disease that affects predominantly a Western population. The incidence and prevalence rates from Asian populations are much lower in comparison. More recent data, however, have shown significantly higher rates in Asians and time trend studies have shown an increase in the incidence of ulcerative colitis (UC) and a similar but lower rise in Crohn's disease (CD). The epidemiological changes that are taking place mirror that of the Western experience seen 50 years previously and seem to occur in parallel with the rapid socioeconomic development taking place in Asia. It appears that certain racial groups are more prone than others to develop IBD. For instance, Indians in South-East Asia have higher rates compared to Chinese and Malays. While there is host genetic predisposition, environmental factor(s) may be responsible for this difference. Migrant studies of South Asians in the UK, where second-generation immigrants have assumed incidence rates as high as the indigenous whites and Asian Jews who develop high incidence rates comparable to Jews from Europe or North America in Israel point to the role of environmental factors. It is unclear which specific factors are responsible. Studies have suggested a change in diet to a more Westernized one may underlie this epidemiological change in the Asian population. It is likely that there are racial groups amongst Asians who are more susceptible to IBD and who will demonstrate a higher frequency of IBD when exposed to putative environmental factors.
journal_name
J Dig Disjournal_title
Journal of digestive diseasesauthors
Goh K,Xiao SDdoi
10.1111/j.1751-2980.2008.00355.xsubject
Has Abstractpub_date
2009-02-01 00:00:00pages
1-6issue
1eissn
1751-2972issn
1751-2980pii
CDD355journal_volume
10pub_type
杂志文章,评审abstract:OBJECTIVES:To investigate whether sending a family history questionnaire to patients prior to undergoing colonoscopy results in an increased availability of family history and better genetic counseling. METHODS:A questionnaire was mailed to patients before they underwent outpatient colonoscopy at a university hospital...
journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12491
更新日期:2017-06-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章,meta分析,评审
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journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1751-2980.2010.00468.x
更新日期:2011-02-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1111/1751-2980.12824
更新日期:2019-12-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2019-06-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/j.1751-2980.2011.00535.x
更新日期:2011-12-01 00:00:00
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pub_type: 杂志文章,实务指引
doi:10.1111/1751-2980.12319
更新日期:2016-02-01 00:00:00
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journal_title:Journal of digestive diseases
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
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更新日期:2014-06-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1443-9573.2007.00271.x
更新日期:2007-02-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
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更新日期:2013-04-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1443-9573.2007.00290.x
更新日期:2007-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/1751-2980.12086
更新日期:2013-11-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章,评审
doi:10.1111/1751-2980.12684
更新日期:2019-01-01 00:00:00
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doi:10.1111/1751-2980.12362
更新日期:2016-07-01 00:00:00
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更新日期:2016-01-01 00:00:00
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journal_title:Journal of digestive diseases
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更新日期:2016-11-01 00:00:00
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更新日期:2015-05-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/j.1751-2980.2012.00616.x
更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2021-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/1751-2980.12250
更新日期:2015-08-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12066
更新日期:2013-08-01 00:00:00
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journal_title:Journal of digestive diseases
pub_type: 杂志文章
doi:10.1111/1751-2980.12053
更新日期:2013-06-01 00:00:00