abstract：:The World population is facing a health challenge never seen since the Spanish influenza of one hundred years ago. During the last months, the scientific community has been debating on the potential harmful effect of Angiotensin-converting-enzyme inhibitors (ACEi) or Angiotensin II receptor Type 1 receptor blockers (A...

journal_title：Minerva endocrinologica

authors： Luzi L,Bucciarelli L,Ferrulli A,Terruzzi I,Massarini S

更新日期：2021-01-12 00:00:00

abstract：:Recent trials have reported sodium-glucose co-transporter 2 (SGLT2) inhibitors to decrease cardiac morbidity and hospitalization in diabetic patients. They have a remarkable ability to modify the cardio-renal axis and have a safer metabolic profile among the existing pharmacotherapy in diabetes. There are multiple pro...

journal_title：Minerva endocrinologica

authors： Khadke S,Jawaid H,Yasmin F,Binte Ali M,Rehman A

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:This study evaluates the effectiveness of continuous glucose monitoring (CGM) in diabetes patients who were on routine dialysis. METHODS:Literature search was conducted in electronic databases and studies were selected by following precise eligibility criteria. Random-effects meta-analyses were performed to...

journal_title：Minerva endocrinologica

authors： Wang F,Wang D,Lyu XL,Sun XM,Duan BH

更新日期：2020-12-03 00:00:00

abstract：:Very-low-calorie ketogenic diet (VLCKD) is a promising lifestyle intervention for the management of overweight and obesity. It is characterized by a restriction of both calories and carbohydrates, while assuring the adequate proteins, fats and micronutrients intake. Significant results in terms of excess body weight l...

journal_title：Minerva endocrinologica

authors： Castellana M,Biacchi E,Procino F,Casanueva FF,Trimboli P

更新日期：2020-11-19 00:00:00

abstract：BACKGROUND:Polycystic ovary syndrome (PCOS) is a complex endocrine disorder with well-established metabolic abnormalities. In the present study, untargeted metabolomics technology was applied to analyze the serum and follicular fluid samples from women with polycystic ovary syndrome and healthy controls using 1H nuclea...

journal_title：Minerva endocrinologica

authors： Xu WL,Liu GY,Zhang N,Ren J,Li XY,Li YQ,Chen Y,Liu JY

更新日期：2020-10-26 00:00:00

abstract：:Familial non-medullary thyroid cancer (FNMTC) constitutes 3-9% of all thyroid cancers and occur in two or more first-degree relatives in the absence of predisposing environmental factors. Out of all FNMTC cases, only 5% are represented by syndromic forms (Gardner's syndrome, familial adenomatous polyposis, Cowden's sy...

journal_title：Minerva endocrinologica

authors： Cirello V

更新日期：2020-10-12 00:00:00

abstract：:Breast cancer is the second most frequent type of cancer worldwide and the most commonly occurring malignancy in women, and its incidence is increasing in most developed and developing countries. There is growing evidence that lifestyle factors, in particular diet may be associated with higher Breast Cancer risk. Some...

journal_title：Minerva endocrinologica

authors： Laudisio D,Castellucci B,Barrea L,Pugliese G,Savastano S,Colao A,Muscogiuri G

更新日期：2020-09-24 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is diabetes that is first diagnosed in the second or third trimester of pregnancy in patients who did not have a history of diabetes before pregnancy. Consequences of GDM include increased risk of macrosomia and birth complications in the infant and an increased risk of maternal typ...

journal_title：Minerva endocrinologica

authors： Šimják P,Anderlová K,Cinkajzlová A,Pařízek A,Kršek M,Haluzík M

更新日期：2020-09-01 00:00:00

abstract：:Subclinical hypothyroidism - i.e., a condition characterized by serum TSH concentrations above the normal reference range in the presence of normal serum T4 levels - affects 4 to 20% of the population living in iodine-sufficient areas. The present work reviews the clinical challenges regarding, on the one hand, the si...

journal_title：Minerva endocrinologica

authors： Chbat J,Ezzat S,Papi G

更新日期：2020-08-03 00:00:00

abstract：AIM:An association between Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) and risk of pancreatitis and pancreatic cancer has been suggested. Since its first description, several new trials (including three cardiovascular outcome trials) have been published, substantially increasing the available data set. This sug...

journal_title：Minerva endocrinologica

authors： Nreu B,Dicembrini I,Tinti F,Mannucci E,Monami M

更新日期：2020-07-23 00:00:00

abstract：:Acromegaly is a rare disease characterized by high levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1). The excess of GH leads to the development of different manifestations in different organs, from subtle signs in the bones and soft tissues to the development of respiratory and cardiac insufficien...

journal_title：Minerva endocrinologica

authors： García-Álvarez M,Climent V

更新日期：2019-06-01 00:00:00

abstract：: ...

journal_title：Minerva endocrinologica

authors： Fattori A,Neri L,Lania A

更新日期：2019-06-01 00:00:00

abstract：: ...

journal_title：Minerva endocrinologica

authors： Koufakis T,Ioannidis I,Zebekakis P,Kotsa K

更新日期：2019-03-01 00:00:00

abstract：:Pregnancy in women with a diagnosis of Cushing' syndrome (CS) is an extremely rare event and its diagnosis and treatment are a real medical challenge. During pregnancy, the hypothalamus-pituitary-adrenal axis undergoes major changes leading to a significant increase in plasma cortisol levels throughout gestation. The ...

journal_title：Minerva endocrinologica

authors： Caimari F,Corcoy R,Webb SM

更新日期：2018-12-01 00:00:00

abstract：:Central adrenal insufficiency (AI) represents a life-threatening disorder that results from a reduced cortisol production due to an impairment production of adrenocorticotropic hormone (ACTH). In particular, secondary AI results from pituitary disease that impedes the release of ACTH, while tertiary AI is caused from ...

journal_title：Minerva endocrinologica

authors： Paragliola RM,Corsello SM

更新日期：2018-06-01 00:00:00

abstract：:The desire to reproduce is a base human instinct. However, for many individuals, the chances of being able to have a genetic child are compromised by a number of factors. For some, therapies aimed at treating serious medical illness, such as cancer; result in a deleterious impact on the function of eggs and sperm in t...

journal_title：Minerva endocrinologica

authors： Brezina PR

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Multicellular spheroids represent an interesting experimental model with promising applications in the pre-clinical studies on anticancer drugs. We recently demonstrated that thyroid spheroids recapitulate the features of the original tissues, in either the differentiated and "stem-like" components. Here we ...

journal_title：Minerva endocrinologica

authors： Cirello V,Gaudenzi G,Grassi ES,Colombo C,Vicentini L,Ferrero S,Persani L,Vitale G,Fugazzola L

更新日期：2018-03-01 00:00:00

abstract：:For decades gross-total resection was the preferred treatment option in childhood-onset craniopharyngioma, assuming that radical strategies at the time of initial diagnosis and treatment would result in cure. Recent reports on long-term prognosis, novel treatment approaches, and molecular genetics provide new insights...

journal_title：Minerva endocrinologica

authors： Müller HL

更新日期：2017-12-01 00:00:00

abstract：:Diabetes mellitus (DM) is a group of metabolic disorders of carbohydrate metabolism in which glucose is underutilized, resulting in hyperglycemia. Reproductive impairment in poorly controlled diabetes mellitus type 1 (T1DM) results from a combined effect of insulin deficiency and hyperglycemia that disrupt the functio...

journal_title：Minerva endocrinologica

authors： Pertynska-Marczewska M,Cypryk K

更新日期：2017-09-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the developed world and its pathogenesis is complex and multifactorial. It is considered the hepatic manifestation of the metabolic syndrome and is the leading cause of hepatic cirrhosis. This review aims to present current knowledge on the ...

journal_title：Minerva endocrinologica

authors： Papanastasiou L,Fountoulakis S,Vatalas IA

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Mild hypothyroidism (thyroid stimulating hormone [TSH] less than 10 mIU/L) induces reversible cognitive dysfunction, which can be evaluated by event related potentials (ERP). So far, only little is known about the impact of subclinical hypothyroidism on ERP as electrophysiological markers of cognitive activi...

journal_title：Minerva endocrinologica

authors： Dejanović M,Ivetić V,Nestorović V,Milanović Z,Erić M

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:A limited number of human and animal studies suggest that a relationship exists between phthalates and obesity, although this is not supported by all research. The purpose of this study was to investigate the relationship between Body Mass Index (BMI) and the levels of phthalates in human blood and urine sam...

journal_title：Minerva endocrinologica

authors： Oktar S,Sungur S,Okur R,Yilmaz N,Ustun I,Gokce C

更新日期：2017-03-01 00:00:00

abstract：:Bariatric surgery has been found to be very useful in treating established type-2 diabetes in obese persons, as well as in borderline diabetics, besides giving a good weight loss. Various modifications of the primary bariatric procedures have been introduced, with differ advantages and better efficacy. Good incretin r...

journal_title：Minerva endocrinologica

authors： Ugale S,Agarwal D,Satwalekar V,Rao N,Ugale A

更新日期：2016-12-01 00:00:00

abstract：:Congenital hypogonadotropic hypogonadism (CHH) is a rare disease characterized by delayed/absent puberty and infertility due to an inadequate secretion or action of gonadotrophin-releasing hormone (GnRH), with an otherwise structurally and functionally normal hypothalamic-pituitary-gonadal (HPG) axis. CHH is genetical...

journal_title：Minerva endocrinologica

authors： Vezzoli V,Duminuco P,Bassi I,Guizzardi F,Persani L,Bonomi M

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate long-term effectiveness and safety of liraglutide in real world. METHODS:A diabetes clinic in Italy systematically collected data of all patients treated with liraglutide. Generalized hierarchical linear regression models for repeated measures were applied to assess tre...

journal_title：Minerva endocrinologica

authors： Ponzani P,Scardapane M,Nicolucci A,Rossi MC

更新日期：2016-03-01 00:00:00

abstract：:Growth hormone (GH) has been recently approved by the Italian Health Authorities for use in transition patients with childhood onset-growth hormone deficiency (CO-GHD). GH in addition to promote linear growth influences several key metabolic processes. In particular, in the transition period, from late adolescent to e...

journal_title：Minerva endocrinologica

authors： Cappa M,Caruso M,Saggese G,Salerno MC,Tonini G

更新日期：2015-03-01 00:00:00

abstract：:Hyponatremia is common in neurosurgical patients and is associated with significant morbidity and mortality. Despite significant research efforts to date, we still lack a complete understanding of the pathophysiological mechanisms underlying hyponatremia in this patient setting. The purpose of this narrative review is...

journal_title：Minerva endocrinologica

authors： Kirkman MA

更新日期：2014-03-01 00:00:00

abstract：AIM:The aim of this paper was to compare serum high sensitivity C-reactive protein (HsCRP) levels and carotid artery intima-media thickness (CIMT) of patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) with that in control subjects. METHODS:Ninety-six subjects with prediabetes, 48 with IFG...

journal_title：Minerva endocrinologica

authors： Karbek B,Cakal E,Cakir E,Bozkurt N,Unsal I,Sahin M,Delibaşi T

更新日期：2013-09-01 00:00:00

abstract：:Obesity has become a national epidemic and a disease of global magnitude. The numbers of patients with obesity have grown exponentially in the last 10 years to the degree that the Centers for Disease Control and Prevention reports that one third of the US population is obese. The prevalence of diabetes has grown by mo...

journal_title：Minerva endocrinologica

authors： Bermudez DM,Pories WJ

更新日期：2013-06-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN1; formerly known as Wermer syndrome) is a rare disorder characterized by the combined occurrence of two or more tumors involving parathyroid, pancreatic islets and anterior pituitary glands; some other tumors have also been described. In most cases it is inherited in an autosom...

journal_title：Minerva endocrinologica

authors： Gaztambide S,Vazquez F,Castaño L

更新日期：2013-03-01 00:00:00

abstract：:The majority of patients with differentiated thyroid cancer are cured with standard primary treatments including surgery, radioactive iodine and TSH suppression. A small proportion of patients who develop radioactive iodine-refractory metastatic disease have few treatment options. Recent discovery of the molecular mec...

journal_title：Minerva endocrinologica

authors： Dadu R,Cabanillas ME

更新日期：2012-12-01 00:00:00

abstract：:New-onset diabetes after transplantation (NODAT) or posttransplant diabetes mellitus is a frequent metabolic complication of organ transplantation. Diabetes incidence rates among transplant recipients are higher than in the general population. The estimated rates are 9-18% after kidney, 20-33% after liver, 26-40% afte...

journal_title：Minerva endocrinologica

authors： Gosmanov AR,Dagogo-Jack S

更新日期：2012-09-01 00:00:00

abstract：:The major issue currently being faced in the management of prostate cancer is the inability to distinguish between indolent prostate tumors that will not present clinically from more aggressive and metastatic prostate cancers that will impact on men's lives. Only a small proportion of prostate cancers can be accounted...

journal_title：Minerva endocrinologica

authors： Biernacka KM,Perks CM,Holly JM

更新日期：2012-06-01 00:00:00

abstract：AIM:The aim of this paper was to determine the prevalence of altered sensorium and their determinants in diabetic ketoacidosis (DKA). METHODS:Retrospective review of medical records for diabetic ketoacidosis admissions over a two year period. RESULTS:A total of 94 admissions for DKA in 89 patients were reviewed. Majo...

journal_title：Minerva endocrinologica

authors： Ekpebegh C,Longo-Mbenza B

更新日期：2011-12-01 00:00:00

abstract：:Although diabetes has been known to increase the risk of cancer for over a century, it was not until recently when this area gained momentum and generated a lot of interest. That is in- part because of the rising global diabetes epidemic and the wide spread use of insulin analogues, metformin and other anti-diabetic a...

journal_title：Minerva endocrinologica

authors： Pandey A,Forte V,Abdallah M,Alickaj A,Mahmud S,Asad S,McFarlane SI

更新日期：2011-09-01 00:00:00

abstract：AIM:The efficacy of low and high fixed dose radioactive iodine (RAI) therapy in patients with toxic nodular goiter was investigated. METHODS:Ninety-three patients (25 males, 68 females) were included into the study (32 patients with toxic adenoma, 61 patients with toxic multinodular goiter). Patients were treated with...

journal_title：Minerva endocrinologica

authors： Sonmez B,Erem C,Dogan I,Ersoz HO,Sonmez M

更新日期：2011-06-01 00:00:00

abstract：:It is known that young female cancer survivors are at higher risk for decreased fertility and early menopause. Because the risk of these outcomes varies by age, cancer type, treatment regimen and other patient-specific characteristics, there is a need for valid tools for measuring and predicting reproductive function ...

journal_title：Minerva endocrinologica

authors： Su HI

更新日期：2010-12-01 00:00:00

abstract：:Nodular goiter encompasses a spectrum of diseases from the incidental asyntomatic small solitary nodule to the large intrathoracic goiter causing pressure symptoms as well as functional complaints. The mainstay in the diagnostic evaluation is related to functional and morphological characterization with serum thyroid-...

journal_title：Minerva endocrinologica

authors： Pelizzo MR,Merante Boschin I,Toniato A,Sorgato N,Marzola MC,Rubello D

更新日期：2010-09-01 00:00:00

abstract：:Sex steroids are essential for reproduction and development in animals and humans, and sex steroids also play an important role in neuroprotection following brain injury. New data indicate that sex-specific responses to brain injury occur at the cellular and molecular levels. This review summarizes the current underst...

journal_title：Minerva endocrinologica

authors： Liu M,Kelley MH,Herson PS,Hurn PD

更新日期：2010-06-01 00:00:00

abstract：:Surgical intervention for breast cancer has continually evolved. The current review reports on updates from the pivotal trials, examines areas of controversy, and explores possible future directions. ...

journal_title：Minerva endocrinologica

authors： Rao R,Wiechmann L

更新日期：2009-12-01 00:00:00