abstract：BACKGROUND:We aimed to characterise the genetic determinants and context of two meropenem-resistant clinical isolates of Acinetobacter baumannii isolated from children hospitalised with bloodstream infections in Dar es Salaam, Tanzania. METHODS:Antimicrobial susceptibility was determined by disc diffusion E-test and b...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Moyo SJ,Manyahi J,Hubbard ATM,Byrne RL,Masoud NS,Aboud S,Manji K,Blomberg B,Langeland N,Roberts AP

更新日期：2021-01-27 00:00:00

abstract：:In the aftermath of a natural disaster, multispecialty rapid response teams are deployed to support health-related relief work. Microbiologists are often part of such teams, along with public health specialists, clinicians and entomologists, and can contribute to the response in multiple ways. The role of a microbiolo...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Viswanathan R,Chakrabarty A,Basu S

更新日期：2021-01-07 00:00:00

abstract：:The neglected tropical disease (NTD) agenda should include a focus on disability when 'planning for the next decade of progress'. Millions of people are currently living with the disabling consequences of NTDs and mental health conditions are frequent among people living with NTDs. Stigma around NTDs is also common. H...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kuper H

更新日期：2020-12-12 00:00:00

abstract：BACKGROUND:Hospital-acquired complications (HACs) contribute to increased morbidity, mortality and hospital costs. However, their burden is often overlooked in resource-limited settings. We sought to determine the incidence, risk factors and effects of HACs on direct medical costs. METHODS:This was a prospective cohor...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sih C,Mbatchou-Ngahane BH,Mboue-Djieka Y,Ngueng-Eke MC,Mbarga NT,Verla VS,Choukem SP

更新日期：2020-11-18 00:00:00

abstract：:Tracking the history of the discovery of mycetoma is not simple because identifying the roots of medical knowledge depends on utilising sources that employ imprecise and sometimes confusing descriptions when compared with those based on modern medical terminology. Ancient sources of information include writings, such ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Hay RJ

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:This cross-sectional survey aimed to assess the knowledge, attitudes and practices (KAP) towards schistosomiasis among rural schoolchildren in Taiz governorate, southwestern Yemen. METHODS:A total of 406 children were screened for urogenital and intestinal schistosomiasis. A pretested questionnaire was used...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Alharazi TH,Al-Mekhlafi HM

更新日期：2020-10-31 00:00:00

abstract：:Countries around the world are facing an enormous challenge due to the COVID-19 pandemic. The pressure that the pandemic inflicts on health systems could certainly impact on the care, control, and elimination of neglected tropical diseases (NTDs). From mid-January 2020, Ethiopia started to prepare for the prevention a...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Abdela SG,van Griensven J,Seife F,Enbiale W

更新日期：2020-10-05 00:00:00

abstract：:The COVID-19 pandemic has exposed health system weaknesses of economically wealthy countries with advanced technologies. COVID-19 is now moving fast across Africa where small outbreaks have been reported so far. There is a concern that with the winter transmission will grow rapidly. Despite efforts of African Governme...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Vilakati PN,Villa S,Alagna R,Khumalo B,Tshuma S,Quaresima V,Nieman NR,Cirillo DM,Raviglione MC

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:Quinolones are broad-spectrum antibiotics, which are used for the treatment of different infectious diseases associated with Enterobacteriaceae. During recent decades, the wide use as well as overuse of quinolones against diverse infections has led to the emergence of quinolone-resistant bacterial strains. H...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Azargun R,Gholizadeh P,Sadeghi V,Hosainzadegan H,Tarhriz V,Memar MY,Pormohammad A,Eyvazi S

更新日期：2020-10-05 00:00:00

abstract：BACKGROUND:To investigate the spatial distribution of congenital syphilis (CS) and its association to social vulnerability indexes in northeast Brazil. METHODS:This was an ecological study referring to all cases of CS and CS deaths recorded in the northeast region of Brazil from 2008 to 2015. Data were obtained from t...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： de Souza CDF,Machado MF,Correia DS,do Carmo RF,Cuevas LE,Santos VS

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Manual white blood cell (WBC) differential counts as a predictor for neonatal sepsis development in a low-resource setting have not been thoroughly evaluated. We hypothesized that manual differentiation (specifically immature:total [I:T] neutrophil ratios) would be feasible and useful as an adjunct to predic...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Golding CN,Schaltz-Buchholzer F,Sanca L,Clipet-Jensen C,Benn CS,Au N,Chipperfield K,Kollmann TR,Amenyogbe NA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:More than 95% of visceral leishmaniasis (VL) cases in Latin America occur in Brazil, most of them in the northeast. The objective of this study was to identify spatial clusters with the highest risks of VL and to analyse the temporal behaviour of the incidence and the effects of social vulnerability on the d...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Andrade AWF,Souza CDF,Carmo RF

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Neurocysticercosis (NCC) is a neglected tropical disease and its diagnosis is still a challenge due to non-specific manifestations. Neuroimaging techniques are used in the diagnosis of NCC, however, due to the high cost of these methods and the advantages presented in the use of immunological tests, such as ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Silva GBD,Faria LSD,Lopes CA,Nunes DS,Ribeiro VS,de Sousa JEN,Paiva GCM,Gonçalves-Pires MRF,Borges IP,Santos MM,Ávila VMR,Júnior ÁF,Costa-Cruz JM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Bacteria are sources of numerous molecules used in treatment of infectious diseases. We investigated effects of molecules produced by 26 Pseudomonas aeruginosa strains against infection of mammalian cell cultures with Trypanosoma cruzi, the aetiological agent of Chagas disease. METHODS:Vero cells were infec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Sass G,Miller Conrad LC,Nguyen TH,Stevens DA

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Aedes aegypti rapid larval surveys are mandatory in Brazil. Here, we retrospectively examined whether the house index estimated by larval surveys served as a useful tool in anticipating epidemics within Brazilian municipalities from 2009-2015. METHODS:We used correlation indices and classification analysis ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Enslen AW,Lima Neto AS,Castro MC

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Early identification of patients at risk of severe dengue disease (DD) is critical to guide its management. We evaluated whether the atypical lymphocyte count (ALC), generated from the Sysmex automated full blood count analyzer, is predictive of severe thrombocytopenia secondary to Dengue infection. METHODS...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Abeysuriya V,Choong CSH,Thilakawardana BU,de Mel P,Shalindi M,de Mel C,Chandrasena L,Seneviratne SL,Yip C,Yap ES,de Mel S

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Dengue is a major cause of acute febrile illness in Sri Lanka. Dengue has historically been considered an urban disease. In 2012-2013, we documented that acute dengue was surprisingly associated with self-reported rural residence in the Southern Province of Sri Lanka. METHODS:Patients admitted with an acute...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mutucumarana CP,Bodinayake CK,Nagahawatte A,Devasiri V,Kurukulasooriya R,Anuradha T,De Silva AD,Janko MM,Østbye T,Gubler DJ,Woods CW,Reller ME,Tillekeratne LG,Lantos PM

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Antibiotic resistance is a global health crisis and irrational prescribing behaviour has been identified as a contributing factor. The current study aimed to assess the knowledge of, attitudes towards and practices regarding antibiotic prescribing of medical doctors providing free healthcare services in the ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Kabba JA,Tadesse N,James PB,Kallon H,Kitchen C,Atif N,Jiang M,Hayat K,Zhao M,Yang C,Chang J,Fang Y

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Characterization of the epidemiology of Escherichia coli bloodstream infection (BSI) in sub-Saharan Africa is lacking. We studied patients with E. coli BSI in northern Tanzania to describe host risk factors for infection and to describe the antimicrobial susceptibility of isolates. METHODS:Within 24 h of ad...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Madut DB,Rubach MP,Kalengo N,Carugati M,Maze MJ,Morrissey AB,Mmbaga BT,Lwezaula BF,Kilonzo KG,Maro VP,Crump JA

更新日期：2020-05-07 00:00:00

abstract：:Antibiotic resistance on account of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-PE) has become a major public health concern in developing countries. The presence of ESBL-PE is associated with increased morbidity, mortality and healthcare costs. There is no active antimicrobial surveillance mechan...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Musa BM,Imam H,Lendel A,Abdulkadir I,Gumi HS,Aliyu MH,Habib AG

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:In urbanized, low-income cities with high rates of congestion, delivery of antiepileptic drugs (AEDs) by unmanned aerial vehicles (drones) to people with epilepsy for both emergency and non-urgent distribution may prove beneficial. METHODS:Conakry is the capital of the Republic of Guinea, a low-income sub-S...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mateen FJ,Leung KHB,Vogel AC,Cissé AF,Chan TCY

更新日期：2020-04-08 00:00:00

abstract：BACKGROUND:Data regarding the incidence of tuberculosis (TB) among people living with diabetes (PLWD) in TB-endemic settings are scarce. We examined TB incidence among PLWD in Indonesia who had previously been screened for latent TB infection (LTBI) and TB disease. METHODS:PLWD (≥18 y of age) in an urban setting were ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： McAllister SM,Koesoemadinata RC,Santoso P,Soetedjo NNM,Kamil A,Permana H,Ruslami R,Critchley JA,van Crevel R,Hill PC,Alisjahbana B

更新日期：2020-02-07 00:00:00

abstract：BACKGROUND:Healthcare-associated infections pose a major, yet often preventable risk to patient safety. Poor hand hygiene among healthcare personnel and unsanitary hospital environments may contribute to this risk in low-income settings. We aimed to describe hand hygiene behaviour and environmental contamination by sea...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Tang K,Berthé F,Nackers F,Hanson K,Mambula C,Langendorf C,Marquer C,Isanaka S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Toxoplasmosis is one of the most common comorbidities in HIV-positive patients with CD4+ T lymphocytes below 200 cells/μl. Early diagnosis and treatment of toxoplasmosis reduces the mortality rate in HIV-positive people. The aim of this study was to estimate the seroprevalence of Toxoplasma gondii infection ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Ahmadpour E,Pishkarie-Asl R,Spotin A,Samadi Kafil H,Didarlu H,Azadi Y,Barac A

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Large numbers of tuberculosis (TB) patients seek care from private for-profit providers. This study aimed to assess and compare TB control activities in the private for-profit and public sectors in Kenya between 2013 and 2017. METHODS:We conducted a retrospective cross-sectional study using routinely collec...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mailu EW,Owiti P,Ade S,Harries AD,Manzi M,Omesa E,Kiende P,Macharia S,Mbithi I,Kamene M

更新日期：2019-12-01 00:00:00

abstract：:Global travel and migration trends have meant a huge increase in the numbers of people exposed to tropical parasitic diseases. Thus, there is an increasing need for robust, reproducible and reliable diagnostic techniques in the field. Advanced molecular and lateral flow techniques have pushed the boundaries of clinica...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Shrivastava J

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Plasmodium vivax malaria has been recognised as an important cause of morbidity in several African countries. The prevalence was previously estimated as 2-5% in eastern Sudan. These estimates are observed to be rising and spreading continuously. The present study was undertaken to investigate the situation o...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Elgoraish AG,Elzaki SEG,Ahmed RT,Ahmed AI,Fadlalmula HA,Abdalgader Mohamed S,Abdallah NI,Abdelgadir O,Ageep TB,El-Sayed BB

更新日期：2019-06-04 00:00:00

abstract：BACKGROUND:Endemic hepatitis E in Southeast Asia increases the risk of death in pregnant women. In Lao People's Democratic Republic, infection with hepatitis E virus (HEV) is widespread in pig farms. No human data are available yet. This study determined the prevalence and risk factors for HEV infection among women of ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Bisayher S,Barennes H,Nicand E,Buisson Y

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Achromobacter xylosoxidans is described as being resistant to antiseptics and disinfectants. We studied in vitro the ability of five strains to survive and grow in such solutions, with and without starvation. METHODS:Bacterial suspensions in rich media and in distilled water were inoculated into eight antis...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Marion-Sanchez K,Pailla K,Cesarine M,Platon MG,Derancourt C,Olive C

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Artemisinin-based combination therapies (ACTs) have proven highly effective in reducing malaria morbidity in sub-Saharan Africa. Artemether-lumefantrine (AL) was introduced in 2005 as a first-line ACT for the treatment of uncomplicated malaria in Rwanda. Monitoring the therapeutic efficacy of ACTs is necessa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Uwimana A,Penkunas MJ,Nisingizwe MP,Warsame M,Umulisa N,Uyizeye D,Musanabaganwa C,Munyaneza T,Ntagwabira E,Hakizimana D,Muvunyi CM,Kayobotsi C,Kabera M,Murindahabi M,Mbituyumuremyi A

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Turkey has a national tuberculosis (TB) control program that follows the standards set by the World Health Organization's (WHO) global TB control program. METHODS:In this record-based retrospective study, contact screening and chemoprophylaxis of 469 TB contacts registered at the Samsun Tuberculosis Dispens...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Dundar C,Oztomurcuk D,Terzi O

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Schistosoma haematobium infection is a major public health problem in most of Africa and the Middle East and praziquantel remains the only drug used for schistosomiasis control, therefore emergence of drug resistance is unavoidable. The antimalarial artemisinin-naphthoquine phosphate combination (co-ArNp) wa...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： El-Beshbishi SN,El Bardicy S,Tadros M,Ayoub M,Taman A

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:We aimed to estimate and compare the ability of clinical tools for dengue diagnosis in a pediatric population. METHODS:We prospectively evaluated episodes of acute febrile syndrome identified during the follow-up of a population-based cohort of children and adolescents residing in a dengue endemic city. We ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Diaz-Quijano FA,Figueiredo GM,Waldman EA,Figueiredo WM,Cardoso MRA,Campos SRC,Costa AA,Pannuti CS,Luna EJA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Hump-nosed pit vipers (Hypnale hypnale) are highly venomous snakes found in Sri Lanka and the Western Ghats region of India. They are the most common cause of venomous snakebites in Sri Lanka, mainly causing local envenoming leading to pain, swelling and necrosis. Systemic envenoming causing acute kidney inj...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Rathnayaka RMMKN,Ranathunga PEAN,Kularatne SAM

更新日期：2019-03-01 00:00:00

abstract：Background:Chronic hepatitis B infection affects 240 million people, with the highest prevalence in Africa and Asia, and results in 700 000 deaths annually. Access to diagnostics, particularly for hepatitis B virus viral load quantification (HBV DNA), is a major barrier to treatment. We aimed to test World Health Organ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Laing N,Tufton H,Ochola E,P'Kingston OG,Maini MK,Easom N

更新日期：2019-01-01 00:00:00

abstract：Background:In Nigeria, little is known about the development of new or additional physical disability during leprosy treatment. The objective of this study was to determine the prevalence and evaluate factors associated with worsening of physical disability during leprosy treatment in Nigeria. Methods:This was a retro...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Chukwu JN,Ekeke N,Nwafor CC,Meka AO,Alphonsus C,Mbah OK,Eze CC,Ukwaja KN

更新日期：2018-11-01 00:00:00

abstract：Background:After new analysis, Sanofi Pasteur now recommends their dengue vaccine (Dengvaxia) should only be given to individuals previously infected with dengue and the World Health Organization's recommendations regarding its use are currently being revised. As a result, the potential costs of performing large-scale ...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Turner HC,Wills BA,Rahman M,Quoc Cuong H,Thwaites GE,Boni MF,Clapham HE

更新日期：2018-08-01 00:00:00

abstract：Background:Preventive chemotherapy (PC), the large-scale administration of anthelminthics, is recommended by the World Health Organization (WHO) for the control of soil-transmitted helminthiasis (STH). Since 2010, donated anthelminthics for STH have boosted the implementation of PC programmes in children, achieving glo...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Montresor A,Trouleau W,Mupfasoni D,Bangert M,Joseph SA,Mikhailov A,Fitzpatrick C

更新日期：2017-10-01 00:00:00

abstract：Background:HIV-associated TB is a serious public health problem in Myanmar. Study objectives were to describe national scale-up of collaborative activities to reduce the double burden of TB and HIV from 2005 to 2016 and to describe TB treatment outcomes of individuals registered with HIV-associated TB in 2015 in the Ma...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Theingi P,Harries AD,Wai KT,Shewade HD,Saw S,Win T,Thein S,Kyi MS,Nyunt Oo H,Aung ST

更新日期：2017-09-01 00:00:00

abstract：:Arboviruses are maintained and transmitted through an alternating biological cycle in arthropods and vertebrates, with largely incidental disease in humans and animals. As such, they provide excellent examples of One Health, as their health impact is inextricably linked to their vertebrate hosts, their arthropod vecto...

journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene

authors： Mackenzie JS,Lindsay MDA,Smith DW,Imrie A

更新日期：2017-06-01 00:00:00