Abstract：
BACKGROUND:Healthcare-associated infections pose a major, yet often preventable risk to patient safety. Poor hand hygiene among healthcare personnel and unsanitary hospital environments may contribute to this risk in low-income settings. We aimed to describe hand hygiene behaviour and environmental contamination by season in a rural, sub-Saharan African hospital setting. METHODS:We conducted a concurrent triangulation mixed-methods study combining three types of data at a hospital in Madarounfa, Niger. Hand hygiene observations among healthcare personnel during two seasons contributed quantitative data describing hand hygiene frequency and its variability in relation to seasonal changes in caseload. Semistructured interviews with healthcare personnel contributed qualitative data on knowledge, attitudes and barriers to hand hygiene. Biweekly environmental samples evaluated microbial contamination from October 2016 to December 2017. Triangulation identified convergences, complements and contradictions across results. RESULTS:Hand hygiene compliance, or the proportion of actions (handrubbing or handwashing) performed out of all actions required, was low (11% during non-peak and 36% during peak caseload seasons). Interviews with healthcare personnel suggesting good general knowledge of hand hygiene contradicted the low hand hygiene compliance. However, compliance by healthcare activity was convergent with poor knowledge of precise hand hygiene steps and the motivation to prevent personal acquisition of infection identified during interviews. Contamination of environmental samples with gram-negative bacilli was high (45%), with the highest rates of contamination observed during the peak caseload season. CONCLUSION:Low hand hygiene compliance coupled with high contamination rates of hospital environments may increase the risk of hospital-acquired infections in sub-Saharan African settings.
journal_name
Trans R Soc Trop Med Hygauthors
Tang K,Berthé F,Nackers F,Hanson K,Mambula C,Langendorf C,Marquer C,Isanaka Sdoi
10.1093/trstmh/trz070subject
Has Abstractpub_date
2019-12-01 00:00:00pages
749-756issue
12eissn
0035-9203issn
1878-3503pii
5586877journal_volume
113pub_type
杂志文章abstract：:Preserved sera from patients with various forms of leishmaniasis, acute and chronic Chagas's disease and from normal individuals were examined for the presence of IgG and IgA antibodies by the IFA test. The leishmanial antigen used in the IFA test was prepared from a hamster infected with the PH8 strain of Leishmania ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(81)90329-1
更新日期：1981-01-01 00:00:00
abstract：:The harmful effects of malaria are most pronounced during first pregnancies and chemoprophylaxis is most effective when given at this time. However, restriction of chemoprophylaxis to first pregnancies might lead to enhanced susceptibility to malaria during second pregnancies. We have investigated this possibility by ...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
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更新日期：1994-11-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(98)90727-1
更新日期：1998-03-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(77)90049-9
更新日期：1977-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(96)90425-3
更新日期：1996-11-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(87)90164-7
更新日期：1987-01-01 00:00:00
abstract：:A survey of Crimean-Congo haemorrhagic fever virus antibody, using the reversed passive haemagglutination inhibition test, was carried out in Saudi Arabia on sera from imported livestock at Jeddah seaport, as well as humans who had contact with imported animals on farms and in quarantine stations. Antibodies were dete...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(97)90014-6
更新日期：1997-09-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(96)90111-x
更新日期：1996-03-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(81)90101-2
更新日期：1981-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2010.05.002
更新日期：2010-08-01 00:00:00
abstract：:The emerging virus strain termed highly pathogenic H5N1 avian influenza (HP-H5N1) has spread widely in the past decade and is now the focus of considerable concern in several sectors. We tested the hypothesis that spatial distributions of veterinary and human HP-H5N1 cases are related to coarse-scale environmental fea...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2008.01.016
更新日期：2008-05-01 00:00:00
abstract：:Tinea imbricata, also known as 'Tokelau', is an uncommon superficial mycosis caused by the anthropophilic dermatophyte Trichophyton concentricum. Cutaneous lesions appear characteristically as scaly and concentric rings that may cover all parts of the body. Often acquired in childhood, tinea imbricata is a chronic dis...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2008.01.002
更新日期：2008-04-01 00:00:00
abstract：:A new antihookworm compound, C.9333 Go./CGP 4540, was evaluated clinically in 65 adult patients with hookworm infection. Several dosage schedules were evaluated to determine an effective, well tolerated and convenient regime. The lowest effective dose was 125 mg administered at four-hourly intervals for three doses. T...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 临床试验,杂志文章
doi：10.1016/0035-9203(77)90017-7
更新日期：1977-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(94)90292-5
更新日期：1994-03-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(77)90107-9
更新日期：1977-01-01 00:00:00
abstract：:A recently described simple kit for isolating African trypanosomes in vitro (KIVI) was tested further with blood samples from man and other animals in Côte d'Ivoire and République du Congo. A high rate of success was achieved, with positive cultures being found 5-36 d after inoculation. The method was also of value in...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(92)90158-9
更新日期：1992-11-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2005.03.003
更新日期：2005-09-01 00:00:00
abstract：:Isolates of Plasmodium falciparum from patients in a Sudanese village exhibiting RI resistance to chloroquine have been typed for allelic variants of 2 merozoite surface antigens, MSP1 and MSP2. Blood forms were taken from each patient before chloroquine was administered, and after parasites had reappeared following t...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(94)90103-1
更新日期：1994-05-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(86)90252-x
更新日期：1986-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(92)90317-6
更新日期：1992-05-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(77)90075-x
更新日期：1977-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/s0035-9203(03)90031-9
更新日期：2003-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(87)90311-7
更新日期：1987-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/trw015
更新日期：2016-04-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(81)90093-6
更新日期：1981-01-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2006.02.017
更新日期：2006-12-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1093/trstmh/trx082
更新日期：2017-10-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/j.trstmh.2003.12.019
更新日期：2004-12-01 00:00:00
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journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章
doi：10.1016/0035-9203(81)90143-7
更新日期：1981-01-01 00:00:00
abstract：:Recent studies delineating bacterial causes of fever in rural Asia indicate a major role for several previously under-recognized pathogens, including Rickettsia and Leptospira. The use of blood culture for the first time to investigate patients with febrile illness in rural Asia has also revealed some unexpected findi...
journal_title：Transactions of the Royal Society of Tropical Medicine and Hygiene
pub_type： 杂志文章,评审
doi：10.1016/j.trstmh.2007.06.004
更新日期：2008-01-01 00:00:00
