abstract：: Objectives : To detect and compare the features of interictal perfusion and volume asymmetry between temporal lobe epilepsy (TLE) patients with and without hippocampal sclerosis (HS). Methods : Sixty-one TLE patients (mean age ...

journal_title：Neurological research

authors： Zhang Y,Dou W,Zuo Z,You H,Lv Y,Hou B,Shi L,Feng F

更新日期：2020-12-15 00:00:00

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：:Objectives: Brain arteriovenous malformations (AVMs) represent high-flow vascular lesions made up of a complex network of feeding arteries and draining veins interposed by a nidus and without a capillary bed. The management of the AVMs represents a challenge, and the optimal treatment should be considered based on the...

journal_title：Neurological research

authors： Gorgan RM,Petrescu GED,Brehar FM

更新日期：2020-12-01 00:00:00

abstract：:Background: Surgery of parasagittal meningiomas (PSMs) is still technically challenging, for the balance between radical resection and preservation of venous circulation. In this article, we'd systemically introduce the technical nuances of a simplified strategy for radical resection of all types of PSMs. All the case...

journal_title：Neurological research

authors： Zhang N,Yang T,Hameed F,Zhang X,Yao Y,Li D,Li C,Yu S,Xu Y,Xia C,Fu X

更新日期：2020-11-11 00:00:00

abstract：OBJECTIVES:To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS. METHODS:Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital ...

journal_title：Neurological research

authors： Lu PL,Niu ZF,Qiu CW,Hu XY

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Hemorrhagic transformation (HT) is a common complication of ischemic stroke. We performed this study to determine whether aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio (AAR) was related to HT, as well as compare the predictive values of AAR, ALT and AST for HT in patients with isch...

journal_title：Neurological research

authors： Wang Y,Qiu K,Song Q,Cheng Y,Liu J,Liu M

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Acquired neurological diseases such as severe traumatic brain or spinal cord injury (SCI) cause irreversible disability. Olfactory ensheathing cell (OEC) transplantation has been trialed as a promising SCI treatment. Extracellular vesicles (EVs), which regulate cell-cell interactions, have recently garnered e...

journal_title：Neurological research

authors： Tu YK,Hsueh YH

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:The novel coronavirus disease (COVID-19) pandemic poses a substantial threat to the health of healthcare personnel on the front line of caring for COVID-19 patients. The Centers for Medicare and Medicaid Services previously announced that all non-essential planned surgeries and procedures should be postpon...

journal_title：Neurological research

authors： Reed LK,Wen J,Liang B,Wang X,Feng D,Huang JH

更新日期：2020-10-01 00:00:00

abstract：INTRODUCTION:Alzheimer's disease (AD) is the most common neurodegenerative disease across the world. The major cause of AD is extensive oxidative stress and inflammation in central nervous system (CNS). Vitamin D3 and E are the most known vitamins that control oxidative stress and mitochondrial respiratory function. Th...

journal_title：Neurological research

authors： Mehrabadi S,Sadr SS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The predictive effect of blood cell ratio on ischemic event has been widely confirmed. Whether PWR and PNR can assess the risk of endovascular treatment (EVT) is largely unclear. This study aimed to investigate the prognostic value of PNR and PWR in acute ischemic stroke patients treated with EVT...

journal_title：Neurological research

authors： Wang L,Cheng Q,Peng M,Lv D,Zi W,Xu G,Liu X

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:To explore clinical features and compare of the difference between conservative treatment and surgical treatmentin prognosis of intracranial aneurysms associated with moyamoya disease (MMD). METHODS:104 patients with MMD a ssociated with intracranial aneurysms diagnosed by digital subtraction angiography (D...

journal_title：Neurological research

authors： Yan J,Lv M,Zeng E,Tang B,Xie S,Hong T

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND/AIMS:Both of neuromyelitis optica spectrum disease (NMOSDs) and idiopathic transverse myelitis (ITM) could present as acute transverse myelitis. However, long-term immunological treatment and prognosis are different for high recurrence of NMOSDs. In this study, we summarized clinical differences between acut...

journal_title：Neurological research

authors： Liu Z,Xie M,Lu Z,Zhang C,Chen H,Xu Y,Zhang M

更新日期：2020-07-01 00:00:00

abstract：:Objective: To determine the time of dementia diagnosis, symptom intensity and to assess the comorbidities.Methods: 110 patients with dementia or mild cognitive impairment were enrolled in this retrospective study. The study group was divided into subgroups: patients with a maximum of three (S ≤ 3 n = 62) and four or m...

journal_title：Neurological research

authors： Niedziela N,Nowak MM,Lis M,Blaszkowska M,Kośmider R,Adamczyk-Sowa M

更新日期：2020-05-01 00:00:00

abstract：:Objective: Nowadays, retinal microvascular structures can be investigated using optical coherence tomography angiography (OCTA). We aimed to evaluate the probable vascular changes in the foveal and peripapillary regions of patients with multiple sclerosis (MS).Methods: A total of 20 patients with relapsing remitting m...

journal_title：Neurological research

authors： Ulusoy MO,Horasanlı B,Işık-Ulusoy S

更新日期：2020-04-01 00:00:00

abstract：:Objectives: Natalizumab (NTZ), a treatment indicated for patients with highly active Relapsing - Remitting Multiple Sclerosis (RRMS), is known to induce increased relative frequency of lymphocytes. Progressive Multifocal Leukoencephalitis (PML) is a rare but serious adverse event related to NTZ. Moreover, reduced L-se...

journal_title：Neurological research

authors： Boziki MK,Karapanayotides T,Papadopoulos G,Lagoudaki R,Melo P,Bakirtzis C,Nikolaidis I,Gounari E,Tsavdaridou V,Skoura L,Afrantou T,Tatsi T,Grigoriadou E,Polyzoidou E,Mandoras N,Giantzi V,Kalogera-Fountzila A,Ioannidis P

更新日期：2020-03-01 00:00:00

abstract：:Objective: To assess the neuropsychological status of pediatric multiple sclerosis (MS) patients and its relationship with clinical variables in a longitudinal study.Methods: Patients with MS (n = 46) and age- and gender-matched healthy control subjects (HCs, n = 53) were given tests of non-verbal reasoning, attention...

journal_title：Neurological research

authors： Öztürk Z,Gücüyener K,Soysal Ş,Konuşkan GD,Konuşkan B,Dikmen AU,Anlar B

更新日期：2020-02-01 00:00:00

abstract：:Objective: The protective effects of 2%-4% hydrogen gas in delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) have been previously reported. This study aimed to assess the neuroprotective effects of high concentration hydrogen (HCH) on DEACMP.Methods: A total of 36 male Sprague-Dawley rats were divi...

journal_title：Neurological research

authors： Shen M,Zheng Y,Zhu K,Cai Z,Liu W,Sun X,Liu J,Zhu D

更新日期：2020-01-01 00:00:00

abstract：:According to recent reports, malnutrition may be associated with a worse prognosis in stroke patients. The aim of this study was to determine the nutritional status of stroke patients and its impact on neurological and functional status of patients in the early post-stroke period. Our prospective study included a tota...

journal_title：Neurological research

authors： Wierzbicki K,Horyniecki M,Mamak D,Szopa M,Buchała J,Stawarz G,Florek S,Adamczyk-Sowa M

更新日期：2020-01-01 00:00:00

abstract：:Objectives: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). Methods: Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.5 h, 6...

journal_title：Neurological research

authors： Hao CH,Ding WX,Sun Q,Li XX,Wang WT,Zhao ZY,Tang LD

更新日期：2019-11-01 00:00:00

abstract：:Objectives: Increased attention is being paid to Asian medicine in balanced total health care. We investigated the effects of mixed exercise including yoga ('Yoga-plus') among elderly individuals. Methods: A total of 385 subjects (72 males and 313 females, 75.5 ± 8.7 years old) participated in a 12-month (M) exercise ...

journal_title：Neurological research

authors： Hishikawa N,Takahashi Y,Fukui Y,Tokuchi R,Furusawa J,Takemoto M,Sato K,Yamashita T,Ohta Y,Abe K

更新日期：2019-11-01 00:00:00

abstract：:Background: IVS5-91G>A (rs3812718) polymorphism of the sodium voltage-gated channel alpha subunit 1 (SCN1A) gene has been associated with inadequate responsiveness to common antiepileptic drugs which act as sodium channel blockers. This study was performed to investigate the effect of IVS5-91G>A (rs3812718) polymorphi...

journal_title：Neurological research

authors： Markovic I,Pejanovic-Skobic N,Bozina N,Susak Sporis I,Sporis D,Basic S

更新日期：2019-10-01 00:00:00

abstract：:Objectives: Neurovascular compression syndromes (NVCS) could be cured with an intravascular device that releases compression of the root entry zone of cranial nerves by changing the course of offending vessels. The purpose of this study was to report our results of in vitro and in vivo experiments with a novel intra-a...

journal_title：Neurological research

authors： Chun Y,Chen Y,Elsisy M,Sukinik J,Shridhar P,Park JK,Kim YB,Hong CK,Chung J

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Rats treated with progesterone (P4) after ischemia show an adequate functional performance despite a significant loss of hippocampal pyramidal neurons, suggesting that P4 could favour a permissive microenvironment for cerebral plasticity mechanisms. The possibility of P4 treatment promoting the survival of ne...

journal_title：Neurological research

authors： Montes P,Vigueras-Villaseñor RM,Rojas-Castañeda JC,Monfil T,Cervantes M,Moralí G

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:In this clinical case-control study, we investigated statin treatment in stroke patients on a range of inflammatory effectors in peripheral blood. We focus on RhoA GTPase and its downstream effectors as a future inflammatory target in stroke treatment. METHODS:Data from 10 patients already on statins at stro...

journal_title：Neurological research

authors： Schultz NEØ,Hasseldam H,Rasmussen RS,Vindegaard N,McWilliam O,Iversen HK,Johansen FF

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:Occipital petalia is an anatomic description where one of the occipital lobes protrudes towards the contralateral side. Transverse sinus (TS) asymmetry might cause diagnostic challenges with regards to thrombotic or compressive pathologies involving these sinuses. In this study, we investigated the associati...

journal_title：Neurological research

authors： Arsava EY,Arsava EM,Oguz KK,Topcuoglu MA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:It is necessary to understand the mechanism of trigeminal neuralgia (TN) and hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous studies implied that inflammatory cytokines induced by demyelination following the nerve injury may be the initiated factor causing neuropathic...

journal_title：Neurological research

authors： Liu MX,Zhong J,Xia L,Dou NN,Li ST

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Here, we investigated inflammatory signs of peripheral nerves in leptin-deficient obese ob/ob mice and the modulating effects of the exogenous iron load. METHODS:Ob/ob and ob/+ control mice were fed with high, standard, or low iron diet for four months. RESULTS:We found intraepidermal nerve fiber degener...

journal_title：Neurological research

authors： Kosacka J,Woidt K,Toyka KV,Paeschke S,Klöting N,Bechmann I,Blüher M,Thiery J,Ossmann S,Baum P,Nowicki M

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Many studies have analyzed the association between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and Parkinson's disease (PD), which yield inconsistent results. This meta-analysis was designed to determine the possible association between the COMT Val158Met polymorphism and the risk of PD in ...

journal_title：Neurological research

authors： Wang YC,Zou YB,Xiao J,Pan CD,Jiang SD,Zheng ZJ,Yan ZR,Tang KY,Tan LM,Tang MS

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:We attempted to determine whether a functional polymorphism of TRPM6 (rs2274924) is associated with susceptibility to epilepsy following ischemic stroke, and to further explore the effect of this polymorphism on serum levels of Mg2+ in post-stroke patients. METHODS:We carried out a case-control study on 378...

journal_title：Neurological research

authors： Fu CY,Chen SJ,Cai NH,Liu ZH,Zhang M,Wang PC,Zhao JN

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Diffusion tensor tractography (DTT) has recently been shown to accurately detect nerve injury and regeneration. This study assesses whether 7-tesla (7T) DTT imaging is a viable modality to observe axonal outgrowth in a 4 cm rabbit sciatic nerve injury model fixed by a reverse autograft (RA) surgical techniqu...

journal_title：Neurological research

authors： Farinas AF,Pollins AC,Stephanides M,O'Neill D,Al-Kassis S,Esteve IVM,Colazo JM,Keller PR,Rankin T,Wormer BA,Kaoutzanis C,Dortch RD,Thayer WP

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Leptin may be associated with cardiovascular disease. We tested to determine whether leptin is a marker for first-ever acute ischemic stroke (AIS) in a nested case-referent study. METHODS:Consecutive patients with first-ever AIS from May 2017 to December 2017 were included. Referents were matched for sex, ag...

journal_title：Neurological research

authors： Liu G,Dong M,Ma S,Fu L,Xiao Y,Zhong L,Geng J

更新日期：2019-02-01 00:00:00

abstract：:Objective: Remote limb ischemic postconditioning (RIPostC) protects the brain from damage induced by transient focal ischemia/reperfusion. However, the underlying mechanism remains unclear. Methods: RIPostC induced by 10 min of occlusion and another 10 min releasing of blood flow for three cycles in the hind limbs was...

journal_title：Neurological research

authors： Liu C,Yang J,Zhang C,Geng X,Zhao H

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To explore the influences of mammalian target of rapamycin (mTOR) signaling pathway on ketamine-induced apoptosis, oxidative stress and Ca2+ concentration in the hippocampal neurons of rats. METHODS:The primary hippocampal neurons isolated from fetal Sprague Dawley rats were treated with ketamine (0, 50, 100...

journal_title：Neurological research

authors： Liu FF,Zhao S,Liu P,Huo SP

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

journal_title：Neurological research

authors： Altintas O,Niftaliyev E,Asil T

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVES:One of the main obstacles of electrode implantation in epilepsy surgery is the electrode shift between implantation and the day of explantation. We evaluated this possible electrode displacement using intraoperative MRI (iopMRI) data and CT/MRI reconstruction. METHODS:Thirteen patients (nine female, four ma...

journal_title：Neurological research

authors： Sommer B,Rampp S,Doerfler A,Stefan H,Hamer HM,Buchfelder M,Roessler K

更新日期：2018-10-01 00:00:00

abstract：:Objective Preoperative magnetic resonance (MR) angiography sometimes shows the absence of collateral flow via the circle of Willis. This study examined whether brain temperature (BT) imaging on multi-voxel proton MR spectroscopy after this finding increases the accuracy of predicting hemispheric ischemia during intern...

journal_title：Neurological research

authors： Tsutsui S,Nanba T,Yoshioka Y,Sasaki M,Fujiwara S,Kobayashi M,Yoshida K,Miyoshi K,Sato S,Ogasawara K

更新日期：2018-08-01 00:00:00

abstract：:Background The distribution of risk factors for stroke is related to gender and age. The main objective of study was to determine the type and frequency of stroke risk factors in patients with first-in-life stroke before the age of 50. Methods Our study included patients under the age of 50 with first-in-life stroke. ...

journal_title：Neurological research

authors： Lasek-Bal A,Kopyta I,Warsz-Wianecka A,Puz P,Łabuz-Roszak B,Zaręba K

更新日期：2018-07-01 00:00:00

abstract：:Objective The aim of the study was to evaluate the parameters for localizing the seizure onset zone in refractory epilepsy patients using cortico-cortical evoked potentials (CCEP). Methods Fifteen patients (nine females) with medically refractory partial epilepsy underwent stereo electro encephalography (SEEG) in Tsin...

journal_title：Neurological research

authors： Zhang N,Zhang B,Rajah GB,Geng X,Singh R,Yang Y,Yan X,Li Z,Zhou W,Ding Y,Sun W

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Cerebral small vessel disease (CSVD) describes a syndrome of neuroimaging, pathological, and associated clinical features caused by small intracranial vascular lesions, which commonly coexists with large artery atherosclerosis (LAA) and has been identified as a major cause of motor impairment over time. In th...

journal_title：Neurological research

authors： Zhu H,Li Z,Lv J,Zhao R

更新日期：2018-05-01 00:00:00

abstract：:Background Transtemporal Doppler (TTD) with middle cerebral artery (MCA) is widely used for right-to-left shunt (RLS) detection. However, an alternative method for patients without suitable temporal bone windows should be established. The present study prospectively evaluated the effectiveness of transorbital Doppler ...

journal_title：Neurological research

authors： Duan Z,Yang Z,Song B,Ma C,Li Y,Du Y,Shang D,Li S,Lou J

更新日期：2018-03-01 00:00:00