Extracellular vesicles isolated from human olfactory ensheathing cells enhance the viability of neural progenitor cells.

abstract：:The possibility of the evaluation of ischemia solely by the momentary values of regional cerebral blood flow (rCBF) was investigated. Ischaemic damage was evaluated histopathologically and by observing albumin extravasation. Unilateral carotid clippings were performed for 1 h and the gerbils evaluated with regard to t...

journal_title：Neurological research

authors： Kadota E

更新日期：1988-12-01 00:00:00

abstract：OBJECTIVES:To estimate the incidence of cognitive impairment (CI) among cognitively healthy, Mexican subjects, and to evaluate the impact of demographic and vascular factors on the conversion to CI and mortality. METHODS:734 eligible subjects (aged 55 to >90 years) from a population-based sample were examined. The cog...

journal_title：Neurological research

authors： Arauz A,Alonso E,Rodríguez-Saldaña J,Reynoso-Marenco M,Benitez IT,Mayorga AM,Rodríguez-Agudelo Y,Romero AV,Cantú C

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:The present study investigated the effects of tetrahydrobiopterin (BH4) on cerebral infarction after transient focal ischemia in rats. METHODS:Focal ischemia (1·5 hours) was created in male Sprague-Dawley rats (250-280 g) by middle cerebral artery occlusion. Some rats were treated with 20 mg/kg tetrahydrob...

journal_title：Neurological research

authors： Tang LL,Zheng JS

更新日期：2011-12-01 00:00:00

abstract：:The objective was to examine the effect of the nitric oxide synthase inhibitor, N omega-nitro-L-arginine methyl ester (L-NAME) on leukocyte adhesion in the cerebral microcirculation during reperfusion following partial forebrain ischemia in the rat. Intravital fluorescence video-microscopy through a closed cranial win...

journal_title：Neurological research

authors： Hudetz AG,Wood JD,Kampine JP

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:It is necessary to understand the mechanism of trigeminal neuralgia (TN) and hemifacial spasm (HFS) in order to seek for an effective noninvasive remedy. As previous studies implied that inflammatory cytokines induced by demyelination following the nerve injury may be the initiated factor causing neuropathic...

journal_title：Neurological research

authors： Liu MX,Zhong J,Xia L,Dou NN,Li ST

更新日期：2019-04-01 00:00:00

abstract：:We have reliable data on the degree of stenosis above which endarterectomy for symptomatic carotid stenosis is beneficial, but benefit is also influenced by other factors, particularly age, sex, the timing of surgery, plaque surface morphology and the nature of the presenting symptomatic event(s). This review will con...

journal_title：Neurological research

authors： Rothwell PM

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China. SUBJECTS AND METHODS:A cross-sectional study (across 19 urban outpatient clinics) on secondary stroke prevention measures w...

journal_title：Neurological research

authors： Wang Y,Wu D,Zhou Y,Zhao X,Wang C,Liu L,Liao X,Wang Y

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:Vascular endothelial growth factor is a potent stimulator of angiogenesis; activation of hypoxia inducible factor-1alpha and p44/42 mitogen-activated protein kinase pathways has been associated with vascular endothelial growth factor production. The present study examined if thrombin modulates vascular endoth...

journal_title：Neurological research

authors： Xu Y,Gu Y,Keep RF,Heth J,Muraszko KM,Xi G,Hua Y

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:It is difficult for the treatment of neurologic tumors with current therapies, including glioma. Despite the advances in cancer therapeutics, the outcomes in these patients remain poor and, therefore, new modalities are required. Recent findings have demonstrated that human umbilical cord blood mesenchymal st...

journal_title：Neurological research

authors： Jiao H,Yang B,Guan F,Li J,Shan H,Song L,Hu X,Liang S,Du Y,Jiang C

更新日期：2011-05-01 00:00:00

abstract：:Dementia is one of the commonest neurological disorders in the elderly population. In regards to the increasing longevity of populations worldwide, prevention of dementia has become a major public health challenge. There has been an intense research in the identification of modifiable risk factors for dementia. These ...

journal_title：Neurological research

authors： Bergmann C,Sano M

更新日期：2006-09-01 00:00:00

abstract：:In addition to its possible role as a replacement source in CNS degenerative diseases, neural transplantation may be used to augment the normal production of neuroactive substances. Our laboratory at the University of Illinois at Chicago has shown, in both acute and chronic pain models, that transplantation of adrenal...

journal_title：Neurological research

authors： Pappas GD,Lazorthes Y,Bès JC,Tafani M,Winnie AP

更新日期：1997-02-01 00:00:00

abstract：INTRODUCTION:Alzheimer's disease (AD) is the most common neurodegenerative disease across the world. The major cause of AD is extensive oxidative stress and inflammation in central nervous system (CNS). Vitamin D3 and E are the most known vitamins that control oxidative stress and mitochondrial respiratory function. Th...

journal_title：Neurological research

authors： Mehrabadi S,Sadr SS

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:The present study was undertaken to evaluate whether resveratrol (RSV) modulates membrane lipid composition, as well as on ganglioside profile in ischemia/reperfusion injury. METHODS:Global cerebral ischemia was induced by four-vessel occlusion for 10 minutes. RSV (30 mg/kg) or vehicle was intraperitoneally...

journal_title：Neurological research

authors： Simão F,Matté A,Breier AC,Kreutz F,Trindade VM,Netto CA,Salbego CG

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Although magnesium is a well-known treatment for vasospasm following subarachnoid hemorrhage, its mechanism of action for cerebral vascular relaxation is not clear. In addition, it is known that L-type calcium (Ca(2+)) channels play a pivotal role in smooth muscle contraction. To investigate the role of L-t...

journal_title：Neurological research

authors： Sharma N,Cho DH,Kim SY,Bhattarai JP,Hwang PH,Han SK

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to investigate the effect of bone mesenchymal stem cells (BMSCs) conditioned medium on BMP4-induced activation of the Smad signaling pathway during the process of neural stem cells differentiation. METHODS:We designed four experimental groups: (A) control group, (B) BMP-4 treatment g...

journal_title：Neurological research

authors： Fang H,Song P,Shen C,Liu X,Li H

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:The present study characterized glial cell injury provoked in adult rat chiasm within 24 hours after a single, high-dose irradiation of 20 Gy. METHODS:All chiasmal glial cells in a section were counted, and the percentage of TUNEL-positive glial cells exhibiting apoptotic morphology was defined as the apopt...

journal_title：Neurological research

authors： Nagayama K,Kurita H,Nakamura M,Kusuda J,Tonari A,Takayama M,Fujioka Y,Shiokawa Y

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Infection is a major complication and risk factor of cerebrospinal fluid (CSF) shunting procedures. Recently, antibiotic-impregnated shunt systems have been developed in an attempt to prevent or reduce the CSF infection. The aim of this study was to determine the efficacy of silver-impregnated polyurethane ve...

journal_title：Neurological research

authors： Izci Y,Secer H,Akay C,Gonul E

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To investigate mechanisms behind the faster rehabilitation of limb fractures when associated with traumatic brain injury (TBI). METHODS:New Zealand rabbits were divided into TBI group and sham-operation group for four studies as follows: (1) blood and cerebrospinal fluid (CSF) were drawn on days 1, 3, and 7 ...

journal_title：Neurological research

authors： Yan H,Zhang HW,Fu P,Liu BL,Jin WZ,Duan SB,Xue J,Liu K,Sun ZM,Zeng XW

更新日期：2013-06-01 00:00:00

abstract：:Traumatic brain injuries (TBIs) are a leading cause of morbidity, mortality, disability and socioeconomic losses in India and other developing countries. Specific topics addressed in this paper include magnitude of the problem, causes, context of injury occurrence, risk factors, severity, outcome and impact of TBIs on...

journal_title：Neurological research

authors： Gururaj G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:The study objectives are (1) to identify factors predicting the excellent visual recovery after transsphenoidal removal of pituitary tumors and (2) to describe the association of excellent visual recovery and early restoration of symmetry of the decompressed optic chiasm. METHODS:Thirty-five patients with v...

journal_title：Neurological research

authors： Yoneoka Y,Hatase T,Watanabe N,Jinguji S,Okada M,Takagi M,Fujii Y

更新日期：2015-01-01 00:00:00

abstract：:The endogenous clock of humans can be influenced by light application to the popliteal region. Previously, it had been assumed that light must fall directly into the eye in order to influence the inner circadian clock. This study, published in 1998, has not been reproduced. We investigated the effects of laser light i...

journal_title：Neurological research

authors： Litscher G

更新日期：2001-12-01 00:00:00

abstract：:In models of middle cerebral artery occlusion using intraluminal suture, the size and the distribution of ischemic injury vary considerably among laboratories. In transcranial models of cerebral ischemia, a more consistent cerebral ischemic lesion is seen in Spontaneously Hypertensive rats (SHR). In the present study,...

journal_title：Neurological research

authors： Dogan A,Başkaya MK,Rao VL,Rao AM,Dempsey RJ

更新日期：1998-04-01 00:00:00

abstract：:Alzheimer disease (AD), a central nervous system degenerative disease, is characterized by abnormal deposition of amyloid-β peptide (Aβ), neurofibrillary tangles formed by hyperphosphorylated tau and synaptic loss. It is widely accepted that Aβ is the chief culprit of AD. Aβ peptide is the cleavage product of amyloid-...

journal_title：Neurological research

authors： Zheng BW,Yang L,Dai XL,Jiang ZF,Huang HC

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

journal_title：Neurological research

authors： Altintas O,Niftaliyev E,Asil T

更新日期：2018-12-01 00:00:00

abstract：:Localization of the pathological structures in relation to the surrounding anatomy and understanding of the surgical anatomy are probably the most important keys to successful neurosurgery. Image-guided surgery is an important tool for understanding an individual's anatomy and for precisely locating the lesion. Head r...

journal_title：Neurological research

authors： Alp MS,Dujovny M,Misra M,Charbel FT,Ausman JI

更新日期：1998-01-01 00:00:00

abstract：:Despite the accumulation of intraoperative data on arteriovenous malformations (AVMs), details of the haemodynamics have not yet been elucidated. A hydraulic model was constructed from silicone and glass tubes to simulate a high-flow AVM. During stepwise obliteration of the nidus, haemodynamic changes were continuousl...

journal_title：Neurological research

authors： Nagasawa S,Kawanishi M,Tanaka H,Ohta T,Nagayasu S,Kikuchi H

更新日期：1993-12-01 00:00:00

abstract：OBJECTIVES:We tested whether repetitive magnetic stimulation (rMS) induces an afferent input to the spinocerebral tract in patients with complex regional pain syndrome (CRPS). METHODS:Cortical and spinal motor evoked potentials (cMEP and sMEP), as well as the contra- and ipsilateral silent period (cCSP and iCSP), were...

journal_title：Neurological research

authors： Krause P,Foerderreuther S,Straube A

更新日期：2005-06-01 00:00:00

abstract：:The intracranial aneurysm, with an estimated occurrence of up to 4% in the general population, belongs among the most dangerous of cerebrovascular diseases. Although less than one-fifth of these cases results in a subarachnoid haemorrhage, the resulting disability and mortality rate is too high. More understanding is ...

journal_title：Neurological research

authors： Duros J,Clark ME,Kufahl RH,Nadvornik P

更新日期：1991-12-01 00:00:00

abstract：OBJECTIVES:Catalpol has been identified to have neuroprotective effect on gerbils subjected to transient global cerebral ischemia. However, the mechanism that catalpol prevents ischemia is still unclear. In the present study, PC12 cells, exposed to oxygen and glucose deprivation (OGD) followed by reperfusion, were used...

journal_title：Neurological research

authors： Wang Z,An LJ,Duan YL,Li YC,Jiang B

更新日期：2008-02-01 00:00:00

abstract：:The decrease in intracellular creatine concentration in Duchenne muscular dystrophy may contribute to the deterioration of intracellular energy homeostasis and may thus be one of the factors aggravating muscle weakness and degeneration. Oral creatine supplementation should have potential in alleviating the clinical sy...

journal_title：Neurological research

authors： Felber S,Skladal D,Wyss M,Kremser C,Koller A,Sperl W

更新日期：2000-03-01 00:00:00