Risk factor profile in patients with stroke at a young age.

Abstract:

:Background The distribution of risk factors for stroke is related to gender and age. The main objective of study was to determine the type and frequency of stroke risk factors in patients with first-in-life stroke before the age of 50. Methods Our study included patients under the age of 50 with first-in-life stroke. The following data obtained from all participants were analyzed: a neuroimaging of the head, wide panel of blood tests, electrocardiogram, transesophageal echocardiography, ultrasound of the carotid/cerebral arteries. 24-hour ECG monitoring and angio-MRI of head were performed in most patients. Results One hundred and eighty-four patients were qualified into the study; mean age - 39 years (female 45%). The female gender was significantly more often associated with diabetes, carotid/cerebral artery stenosis, myocardial infarction, cardiomyopathy and risk factors associated with lifestyle. More than half of the patients presented at least two risk stroke factors. The most frequent categories of risk factors were related to arteries and metabolic diseases. Vascular risk factors were among the most frequent in individual age categories. Hereditary stroke-burden was significant in the patient before the age of 20.15% of the patients haven't got known stroke risk factor. Conclusions Angiopathy is the most common risk factor for stroke at a young age. More than half of the patients with stroke at a young age have at least two independent risk factors for stroke. In the first two decades of life, the most frequent risk factors for stroke are heart diseases; arterial diseases play a dominant role in the consecutive three decades.

journal_name

Neurol Res

journal_title

Neurological research

authors

Lasek-Bal A,Kopyta I,Warsz-Wianecka A,Puz P,Łabuz-Roszak B,Zaręba K

doi

10.1080/01616412.2018.1455367

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

593-599

issue

7

eissn

0161-6412

issn

1743-1328

journal_volume

40

pub_type

杂志文章
  • Is hyperlipidemia correlated with longer survival in patients with amyotrophic lateral sclerosis?

    abstract::Amyotrophic lateral sclerosis (ALS) is the most serious form of degenerative motor neuron disease in adults, whose relentless course leads to death within 2-5 years, generally due to respiratory failure. Apart from the age and site of onset, no other factors have consistently demonstrated to be related to the ALS outc...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132812Y.0000000049

    authors: Dedic SI,Stevic Z,Dedic V,Stojanovic VR,Milicev M,Lavrnic D

    更新日期:2012-07-01 00:00:00

  • The effects of halothane on somatosensory and flash visual evoked potentials during operations.

    abstract::Intraoperative use of somatosensory evoked potentials (SEP's) to monitor intracranial aneurysm surgery and flash visual evoked potentials (F-VEP's) for parasellar surgery have been routinely employed in our clinic. We found that both EP modalities are sensitive to the changing concentration of our standard hypotensive...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1985.11739701

    authors: Wang AD,Costa e Silva I,Symon L,Jewkes D

    更新日期:1985-06-01 00:00:00

  • Intracerebral hemorrhage survival: French register data.

    abstract::Cerebral hemorrhages are subject to a heavy short- and long-term case fatality. A study of prognostic factors and of relative survival based on the data of a population registry is of great value to study patients having a hematoma of all ages, irrespective of the method of care. We have listed 183 patients having a c...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2000.11740754

    authors: el Chami B,Milan C,Giroud M,Sautreaux JL,Faivre J

    更新日期:2000-12-01 00:00:00

  • Gene expression profile of acupuncture treatment in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease model.

    abstract:OBJECTIVES:To find new biomarkers by stimulating acupuncture point GB34 (Yangneungcheon) which has neuroprotective effect on the mouse model of Parkinson's disease, analysis of cDNA microarray on mRNAs of the substantia nigra was performed. METHODS:Male C57BL/6 mice were divided into two groups: 1-methyl-4-phenyl-1,2,...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164109X12537002794165

    authors: Hong MS,Park HK,Yang JS,Park HJ,Kim ST,Kim SN,Park JY,Song JY,Park HK,Jo DJ,Park SW,HwanYun D,Ban JY,Chung JH

    更新日期:2010-02-01 00:00:00

  • Neuroprotective effect of basic fibroblast growth factor on wobbler mouse motor neuron disease.

    abstract::Basic fibroblast growth factor (bFGF) possesses neuroprotective effects on a variety of neurons. Here we report that it delays progression of motor neuron disease (MND) in the wobbler mouse. After initial diagnosis of MND at post-natal age 3-4 weeks, wobbler mice receive either recombinant human bFGF (1 mg kg-1, n = 1...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:

    authors: Ikeda K,Iwasaki Y,Tagaya N,Shiojima T,Kobayashi T,Kinoshita M

    更新日期:1995-12-01 00:00:00

  • Screening and treatment of unruptured cerebral aneurysms.

    abstract::Thirty outpatients with unruptured cerebral aneurysms screened by computed angiotomography have been analysed and followed up in our clinic since 1979. Seventeen were men and the age range was 41 to 74 years old (mean 57.7 years). Patients had no or only mild neurological symptoms, such as headache, sensorimotor or sp...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1986.11739736

    authors: Yamamoto Y,Asari S,Sunami N,Kunishio K,Fukui K,Sadamoto K

    更新日期:1986-06-01 00:00:00

  • The relationship between brain microbleeds and homeostatic markers in the treatment of ischemic stroke.

    abstract:OBJECTIVES:There is no definitive data regarding the usefulness of Brain microbleeds (BMBs) as an imaging marker with homeostatic markers to predict intracerebral hemorrhage (ICH) and ischemic stroke risk to personalize decisions on anticoagulation in AF. In this study, we prospectively evaluated clinical, radiological...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1517111

    authors: Altintas O,Niftaliyev E,Asil T

    更新日期:2018-12-01 00:00:00

  • Uncorrected traumatic coagulopathy is associated with severe brain swelling during decompressive surgery to evacuate a supratentorial intradural mass lesion in patients with traumatic brain injury.

    abstract:OBJECTIVE:This study investigated the relationship between traumatic coagulopathy and severe brain swelling (SBS) during decompressive surgery to evacuate a supratentorial intradural mass lesion in patients with traumatic brain injury (TBI). METHODS:A retrospective study was conducted in 96 patients who consecutively ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132813Y.0000000187

    authors: Wang K,Xue Y,Chen X,Zhou B,Lou M

    更新日期:2013-07-01 00:00:00

  • Protective effect of BAG5 on MPP+-induced apoptosis in PC12 cells.

    abstract:OBJECTIVES:Parkinson's disease (PD) is the most common neurodegenerative disease in humans, and an abundance of evidence has implicated apoptosis signaling pathways in the neurodegeneration of PD. The purpose of this study was to assess the role of B-cell lymphoma 2 (Bcl-2)-associated athanogene 5 (BAG5) protein, whic...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132812Y.0000000102

    authors: Ma M,Wang X,Ding X,Jing J,Ma Y,Teng J

    更新日期:2012-12-01 00:00:00

  • Stereotactic software for the GE 8800 CT scanner.

    abstract::A computer software program (Seapit) was developed for precise determination of intracranial targets identified by stereotactic computed tomography (CT). This program was added to the software of a GE 8800 CT scanner to perform the following operations: millimetre precise calculation and display of the rectilinear coo...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1987.11739781

    authors: Lunsford LD,Listerud JA,Rowberg AH,Latchaw RE

    更新日期:1987-06-01 00:00:00

  • Cognitive impairment and whole brain diffusion in patients with carotid artery disease and ipsilateral transient ischemic attack.

    abstract:OBJECTIVES:Transient ischemic attack (TIA) with carotid artery disease (CAD) can increase the risk of cognitive decline. However, the neural mechanisms of the disorder remain unclear. The aim of this study was, using diffusion tensor imaging (DTI), to detect microstructural changes in patients with symptomatic CAD pres...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132813Y.0000000255

    authors: Guo J,Wang S,Li R,Chen N,Zhou M,Chen H,Gong Q,He L

    更新日期:2014-01-01 00:00:00

  • Combination of blood flow asymmetry in the cerebral and cerebellar hemispheres on brain perfusion SPECT predicts 5-year outcome in patients with symptomatic unilateral major cerebral artery occlusion.

    abstract:BACKGROUND AND OBJECTIVE:Misery perfusion increases the risk of stroke recurrence in patients with symptomatic major cerebral artery occlusion. The ratio of brain perfusion contralateral-to-affected asymmetry in the cerebellar hemisphere to brain perfusion affected-to-contralateral asymmetry in the cerebral hemisphere ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/1743132813Y.0000000300

    authors: Nomura J,Ogasawara K,Saito H,Terasaki K,Matsumoto Y,Takahashi Y,Ogasawara Y,Saura H,Yoshida K,Sato Y,Kubo Y,Ogawa A

    更新日期:2014-03-01 00:00:00

  • Thrombolysis with alteplase for acute ischemic stroke patients with atrial fibrillation.

    abstract:OBJECTIVE:Intravenous administration of recombinant tissue plasminogen activator (rtPA) is known as the only approved treatment for acute ischemic stroke. However, it is still controversial whether acute ischemic stroke patients with atrial fibrillation should receive rtPA therapy. METHODS:We studied 99 patients altog...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164110X12656393665206

    authors: Zhang JB,Ding ZY,Yang Y,Sun W,Hai F,Sui XN,Li XY,Wang HZ,Wang XT,Zheng JL

    更新日期:2010-05-01 00:00:00

  • Endothelin receptors A and B are expressed in distinct cellular compartments of rat hippocampus following global ischemia: an immunocytochemical study.

    abstract:OBJECTIVES:The syntheses of endothelin receptors A and B were previously shown to be upregulated in rat dorsal hippocampus after traumatic brain injury. Here we characterize endothelin receptor A and endothelin receptor B cellular distribution in hippocampus after permanent global brain ischemia and their possible asso...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164111X12881719352291

    authors: Kreipke CW,Reynolds CA,Schafer PC,Schafer S,Pirooz R,Rafols JA

    更新日期:2011-03-01 00:00:00

  • Non-invasive brainstem monitoring: the ocular microtremor.

    abstract::The ocular microtremor (OMT) is mediated by the oculomotor area of the brainstem and is altered in several pathologic states, including traumatic brain injury, general anesthesia, brain death, coma, Parkinsonism and multiple sclerosis. The EYETECT tremor monitor is a non-invasive means of measuring the frequency and a...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/016164107X240198

    authors: Robertson J,Timmons S

    更新日期:2007-10-01 00:00:00

  • Occipital petalia as a predictive imaging sign for transverse sinus dominance.

    abstract:OBJECTIVES:Occipital petalia is an anatomic description where one of the occipital lobes protrudes towards the contralateral side. Transverse sinus (TS) asymmetry might cause diagnostic challenges with regards to thrombotic or compressive pathologies involving these sinuses. In this study, we investigated the associati...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2018.1560643

    authors: Arsava EY,Arsava EM,Oguz KK,Topcuoglu MA

    更新日期:2019-04-01 00:00:00

  • Brain volume and perfusion asymmetry in temporal lobe epilepsy with and without hippocampal sclerosis.

    abstract:: Objectives : To detect and compare the features of interictal perfusion and volume asymmetry between temporal lobe epilepsy (TLE) patients with and without hippocampal sclerosis (HS). Methods : Sixty-one TLE patients (mean age ...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2020.1853988

    authors: Zhang Y,Dou W,Zuo Z,You H,Lv Y,Hou B,Shi L,Feng F

    更新日期:2020-12-15 00:00:00

  • Cell proliferation in ependymal/subventricular zone and nNOS expression following focal cerebral ischemia in adult rats.

    abstract::Neuronal nitric oxide synthase (nNOS) regulates neurogenesis in normal developing brain, but the role of nNOS in neurogenesis in the ischemic brain remains unclear. To investigate the temporal and spatial relationship between cell proliferation of the ependymal/subventricular zone (SVZ), a principal neuroproliferative...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164106X91942

    authors: Zhang P,Liu Y,Li J,Kang Q,Tian Y,Chen X,Shi Q,Song T

    更新日期:2006-01-01 00:00:00

  • Direct percutaneous carotid artery stenting with distal protection: technical case report.

    abstract::We describe the technique of percutaneous carotid artery stent placement with distal protection in a patient in whom marked innominate artery ectasia prevented transfemoral access to the right common carotid artery. After induction of general anesthesia, ultrasound was used to guide direct puncture of the common carot...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164104225013978

    authors: Perez-Arjona EA,DelProsto Z,Fessler RD

    更新日期:2004-04-01 00:00:00

  • Evaluation of cerebral autoregulation following diffuse brain injury in rats.

    abstract::The normal cerebral circulation has the ability to maintain a stable cerebral blood flow over a wide range of cerebral perfusion pressures and this is known as cerebral autoregulation. This autoregulation may be impaired in the injured brain. Closed head injury was induced in 28 Sprague-Dawley rats weighing 400-450 g....

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1997.11740832

    authors: Prat R,Markiv V,Dujovny M,Misra M

    更新日期:1997-08-01 00:00:00

  • Association between Endothelial nitric oxide synthase G894T gene polymorphism and risk of ischemic stroke in North Indian population: a case-control study.

    abstract:BACKGROUND AND PURPOSE:Stroke is a multi-factorial disease influenced by both genetic and environmental factors. The aim of this case-control study was to determine the association between Endothelial Nitric Oxide Synthase G894T (rs1799983) gene polymorphism and susceptibility to ischemic stroke (IS) in North Indian po...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2016.1181376

    authors: Kumar A,Misra S,Kumar P,Sagar R,Prasad K,Pandit AK,Chakravarty K,Kathuria P,Yadav AK

    更新日期:2016-07-01 00:00:00

  • Extracellular vesicles isolated from human olfactory ensheathing cells enhance the viability of neural progenitor cells.

    abstract:OBJECTIVE:Acquired neurological diseases such as severe traumatic brain or spinal cord injury (SCI) cause irreversible disability. Olfactory ensheathing cell (OEC) transplantation has been trialed as a promising SCI treatment. Extracellular vesicles (EVs), which regulate cell-cell interactions, have recently garnered e...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.2020.1794371

    authors: Tu YK,Hsueh YH

    更新日期:2020-11-01 00:00:00

  • Needle-free acupuncture benefits both patients and clinicians.

    abstract:OBJECTIVE:This study examined whether a needle-free acupuncture can be an alternative to conventional needle injection acupuncture. METHODS:Patients (n=101) suffering myofascial shoulder pain were randomly assigned to either needle-free or conventional needle injection acupuncture group. Bee venom was administered int...

    journal_title:Neurological research

    pub_type: 杂志文章,随机对照试验

    doi:10.1179/016164109X12537002793760

    authors: An K,Kim YS,Kim HY,Lee H,Hahm DH,Lee KS,Kang SK

    更新日期:2010-02-01 00:00:00

  • Thrombin up-regulates vascular endothelial growth factor in experimental gliomas.

    abstract:OBJECTIVE:Vascular endothelial growth factor is a potent stimulator of angiogenesis; activation of hypoxia inducible factor-1alpha and p44/42 mitogen-activated protein kinase pathways has been associated with vascular endothelial growth factor production. The present study examined if thrombin modulates vascular endoth...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/174313209X385699

    authors: Xu Y,Gu Y,Keep RF,Heth J,Muraszko KM,Xi G,Hua Y

    更新日期:2009-09-01 00:00:00

  • Positron emission tomographic evaluation of histological malignancy in gliomas using oxygen-15 and fluorine-18-fluorodeoxyglucose.

    abstract::HEADTOME III, a high resolution PET, has been employed using 15O and 18F labelled pharmaceuticals to evaluate histological malignancy of gliomas preoperatively. PET study was applied on eighteen preoperative gliomas including two recurrent cases. Haemocirculatory and metabolic indices of regional cerebral blood flow (...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1986.11739749

    authors: Mineura K,Yasuda T,Kowada M,Shishido F,Ogawa T,Uemura K

    更新日期:1986-09-01 00:00:00

  • Hyperbaric oxygenation in fluid microembolism.

    abstract::Because clinicians require objectively demonstrable neurological deficits to confirm a diagnosis, the recognition of embolic events in the nervous system is generally restricted to the effects of ischemic necrosis produced by arterial occlusion. However, magnetic resonance imaging (MRI) has shown that lesser degrees o...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1179/016164107X181789

    authors: James PB

    更新日期:2007-03-01 00:00:00

  • Application of magnetic resonance angiography to neurosurgical practice: a critical review of 150 cases.

    abstract::The potential role of magnetic resonance angiography (MRA) in clinical neurosurgical practice was evaluated in 150 consecutive patients in an attempt to define clinical situations in which it aided in diagnosis, helped guide treatment options, and/or possibly eliminated the need for conventional catheter angiography. ...

    journal_title:Neurological research

    pub_type: 杂志文章,评审

    doi:10.1080/01616412.1992.11740086

    authors: Awad IA,Mckenzie R,Magdinec M,Masaryk T

    更新日期:1992-12-01 00:00:00

  • Beta-amyloid-induced reactive astrocytes display altered ability to support dendrite and axon growth from mouse cerebral cortical neurons in vitro.

    abstract:OBJECTIVES:The presence of beta-amyloid (betaA) deposition, induction of reactive gliosis and dystrophic neurites, is a characteristic feature of neuritic plaques in Alzheimer's disease. In vitro, betaA-exposed astrocytes become reactive, similar to astrocytes in contact with betaA plaques in vivo. How betaA-exposed re...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1179/016164105X40020

    authors: Monnerie H,Esquenazi S,Shashidhara S,Le Roux PD

    更新日期:2005-07-01 00:00:00

  • Early decrease of P-glycoprotein in the endothelium of the rat brain capillaries after moderate dose of irradiation.

    abstract::In this study, we examined the degree of disruption of blood-brain barrier (BBB) in irradiated rat brains using P-glycoprotein, one of the functional molecules of BBB, as a marker. In the animal experiments, disruption of BBB has been mainly studied at the acute stage of brain edema caused by a lethal dose of irradiat...

    journal_title:Neurological research

    pub_type: 杂志文章

    doi:10.1080/01616412.1999.11740920

    authors: Mima T,Toyonaga S,Mori K,Taniguchi T,Ogawa Y

    更新日期:1999-03-01 00:00:00

  • COMT Val158Met polymorphism and Parkinson's disease risk: a pooled analysis in different populations.

    abstract:OBJECTIVE:Many studies have analyzed the association between the catechol-O-methyltransferase (COMT) Val158Met polymorphism and Parkinson's disease (PD), which yield inconsistent results. This meta-analysis was designed to determine the possible association between the COMT Val158Met polymorphism and the risk of PD in ...

    journal_title:Neurological research

    pub_type: 杂志文章,meta分析

    doi:10.1080/01616412.2018.1564183

    authors: Wang YC,Zou YB,Xiao J,Pan CD,Jiang SD,Zheng ZJ,Yan ZR,Tang KY,Tan LM,Tang MS

    更新日期:2019-04-01 00:00:00