Non-invasive brainstem monitoring: the ocular microtremor.

abstract：OBJECTIVE:This review article summarizes in vitro, in vivo, and clinical evidence pertaining to temozolomide (TMZ) and bevacizumab (BEV) efficacy and mechanism of action in gliomas. METHODS:Relevant publications published before June 2013 in PubMed database were reviewed. RESULTS:Temozolomide and BEV are current chem...

journal_title：Neurological research

authors： Nanegrungsunk D,Onchan W,Chattipakorn N,Chattipakorn SC

更新日期：2015-02-01 00:00:00

abstract：:Intraoperative use of somatosensory evoked potentials (SEP's) to monitor intracranial aneurysm surgery and flash visual evoked potentials (F-VEP's) for parasellar surgery have been routinely employed in our clinic. We found that both EP modalities are sensitive to the changing concentration of our standard hypotensive...

journal_title：Neurological research

authors： Wang AD,Costa e Silva I,Symon L,Jewkes D

更新日期：1985-06-01 00:00:00

abstract：:Cerebral blood flow (CBF), 113mIndium-DPTA, and 14C-glucose extraction were measured simultaneously in rat brain from 2 to 58 days following a thermal insult. In the early stage of a cold induced lesion (2 days), the blood-brain barrier (BBB) was disrupted with resulting leakage and diffusionary loss of both glucose a...

journal_title：Neurological research

authors： Pollay M,Stevens FA

更新日期：1980-01-01 00:00:00

abstract：:We describe the advantages and clarify the technical key points of a microendoscopic, minimally invasive technique to the posterior surgical approach for cervical degenerative disease. The authors studied the microendoscopic posterior approach using the METRx system in both cadaver models and in clinical cases. This n...

journal_title：Neurological research

authors： Yuguchi T,Nishio M,Akiyama C,Ito M,Yoshimine T

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing c...

journal_title：Neurological research

authors： Ramírez-Zamora A,Alarcón T

更新日期：2010-04-01 00:00:00

abstract：:This paper describes a test prototype for precision robot-assisted surgery using a hexapod operating robot and a movable operating cockpit for tactile feedback. The objective of the work described is twofold: 1, to evaluate the use of hexapod robots for precisely manipulating endoscopes and surgical instruments in sub...

journal_title：Neurological research

authors： Urban V,Wapler M,Weisener T,Schönmayr R

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...

journal_title：Neurological research

authors： Rijbroek A,Boellaard R,Vriens EM,Lammertsma AA,Rauwerda JA

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Disturbances in the hypothalamo-pituitary axis are supposed to modulate activity of multiple sclerosis (MS). We hypothesised that the extent of HYP damage may determine severity of MS and may be associated with the disease evolution. We suggested fatigue and depression may depend on the degree of damage of t...

journal_title：Neurological research

authors： Kantorová E,Poláček H,Bittšanský M,Baranovičová E,Hnilicová P,Čierny D,Sivák Š,Nosáľ V,Zeleňák K,Kurča E

更新日期：2017-04-01 00:00:00

abstract：:An approach to aneurysms arising at the bifurcation of the basilar artery and its neighborhood is described. The temporal pole of the nondominant side is retracted posteriorly to provide a wide operative field and a better view of aneurysms. ...

journal_title：Neurological research

authors： Sano K

更新日期：1980-01-01 00:00:00

abstract：:Excessive calcium influx has been implicated in the pathophysiology of ischemic cerebral damage. The effects of nimodipine, a calcium antagonist, on the Na(+)-K+/MG+2 ATPase activity, Ca+2/Mg+2 ATPase, lipid peroxidation, and early ultrastructural findings were examined at the acute stage of ischemia in the rat brain....

journal_title：Neurological research

authors： Ildan F,Göçer AI,Tuna M,Polat S,Kaya M,Isbir T,Cetinalp E

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:4-N-trimethylammonium-3-hydroxybutyric acid (L-carnitine) is an endogenous mitochondrial membrane compound and some studies have reported that L-carnitine could effectively protect various cells against oxidative injury both in vitro and in vivo. In the present study, we used the human neuroblastoma SH-SY5Y ...

journal_title：Neurological research

authors： Yu J,Ye J,Liu X,Han Y,Wang C

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Tadalafil is a selective phosphodiesterase type 5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction. Less is known about the electroencephalography (EEG) effects of PDE-5 inhibitors, and the present study, therefore, examined the risk of EEG abnormalities associated with tadalafil. METHOD:...

journal_title：Neurological research

authors： Okuyucu EE,Guven O,Duman T,Gorur S,Melek IM,Akcin S,Yilmazer S

更新日期：2009-04-01 00:00:00

abstract：:Vestibular neuritis (VN) rapidly damages unilateral vestibular periphery, inducing severe balance disorders. In most cases, such vestibular imbalance is gradually restored to within the normal level after clinical therapies. This successive clinical recovery occurs due to regeneration of vestibular periphery and/or ac...

journal_title：Neurological research

authors： Kitahara T,Kondoh K,Morihana T,Okumura S,Horii A,Takeda N,Kubo T

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS. METHODS:Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital ...

journal_title：Neurological research

authors： Lu PL,Niu ZF,Qiu CW,Hu XY

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:In order to test for mechanisms of whole brain radio therapy side effects and possible neuroprotective measures, a rodent model is desirable. In many models, a high single dose of 8-20 Gray (Gy) of whole brain irradiation is used. These experimental radiation protocols do not closely reflect the clinical situ...

journal_title：Neurological research

authors： Semmler A,Garbe S,Moskau S,Frisch C,Eter N,Schlegel U,Linnebank M

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:The suppressor gene maspin (Serpin B5) is a promising candidate for future treatment. We have examined the messenger RNA (mRNA) and protein expression of maspin in normal breast tissue, breast cancer primaries, brain metastases and breast cancer cell lines. Results were compared to hormone receptor expressio...

journal_title：Neurological research

authors： Stark AM,Schem C,Maass N,Hugo HH,Jonat W,Mehdorn HM,Held-Feindt J

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Crossed-uncrossed differentials (CUDs) are viewed as surrogates for interhemispheric transfer time (IHTT). Not uncommonly CUDs assume statistically significant negative values (inverted CUDs). This raises doubts of the accepted interpretation of CUDs, i.e. intra- and inter-hemispheric routings of signals in ...

journal_title：Neurological research

authors： Derakhshan I

更新日期：2006-10-01 00:00:00

abstract：:Decreased metabolic rate may precede cognitive impairment in Alzheimer's disease (AD) and is thus an early occurring hallmark. Several observations in post-mortem brain indicate that activated neurons are better able to withstand aging and AD, a phenomenon paraphrased by us as 'use it or lose it'. Moreover, a number o...

journal_title：Neurological research

authors： Swaab DF

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:In the present study, we investigated the effects of treadmill exercise on microglial activation and the subsequent release of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6 and IL-1-beta in the hippocampus in a rat model of type 2 diabetes. METHODS:At 30 weeks of age, diabetic (Zucker diabeti...

journal_title：Neurological research

authors： Yoo DY,Chae J,Jung HY,Yim HS,Kim JW,Nam SM,Kim DW,Choi JH,Seong JK,Yoon YS,Hwang IK

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:The utility of apparent diffusion coefficient (ADC) values was evaluated for the differential diagnosis of ganglioglioma. METHODS:Ten consecutive patients, five men and five women, aged from 14 to 67 years, with histologically proven supratentorial gangliogliomas, underwent diffusion-weighted magnetic reson...

journal_title：Neurological research

authors： Kikuchi T,Kumabe T,Higano S,Watanabe M,Tominaga T

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:To determine the functional abnormalities of the Leu89Pro mutation in connexin32 (CX32), which we have previously reported is present within an X-linked dominant Charcot-Marie-Tooth disease family. In this family, male patients were moderately to severely affected. METHODS:We performed immunofluorescence to ...

journal_title：Neurological research

authors： Da Y,Wang W,Liu Z,Chen H,Di L,Previch L,Chen Z

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether cerebral inflammation in ischemic rats was reduced by a neuroprotective action of pre-ischemic tumor necrosis factor-alpha up-regulation, which down-regulated matrix metalloproteinase-9 activity via extracellular signal-regulated kinase 1/2 phosphorylation. MATERIAL AND METHODS...

journal_title：Neurological research

authors： Curry A,Guo M,Patel R,Liebelt B,Sprague S,Lai Q,Zwagerman N,Cao FX,Jimenez D,Ding Y

更新日期：2010-09-01 00:00:00

abstract：:The objective of this study was to investigate the effects of transplanted bone marrow mesenchymal stem cells (BMSCs) administered via internal jugular vein injection, carotid artery injection, or intraventricular transplantation for the treatment of cerebral infarction, which was modeled in rats. The neurological sco...

journal_title：Neurological research

authors： Ruan GP,Han YB,Wang TH,Xing ZG,Zhu XB,Yao X,Ruan GH,Wang JX,Pang RQ,Cai XM,He J,Zhao J,Pan XH

更新日期：2013-03-01 00:00:00

abstract：:In order to investigate the functional role of endothelium and vasoeffector mechanism in cerebrovascular responses to neuropeptides, the stainless steel cannula inserting method was applied to examine the responses to intraluminally-applied bradykinin, substance P and vasopressin in isolated and perfused canine basila...

journal_title：Neurological research

authors： Tsuji T,Cook DA

更新日期：1995-06-01 00:00:00

abstract：:Objectives: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). Methods: Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.5 h, 6...

journal_title：Neurological research

authors： Hao CH,Ding WX,Sun Q,Li XX,Wang WT,Zhao ZY,Tang LD

更新日期：2019-11-01 00:00:00

abstract：:Background Transtemporal Doppler (TTD) with middle cerebral artery (MCA) is widely used for right-to-left shunt (RLS) detection. However, an alternative method for patients without suitable temporal bone windows should be established. The present study prospectively evaluated the effectiveness of transorbital Doppler ...

journal_title：Neurological research

authors： Duan Z,Yang Z,Song B,Ma C,Li Y,Du Y,Shang D,Li S,Lou J

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:High-sensitivity C-reactive protein (hs-CRP) is an inflammatory marker that is associated with the outcomes of ischemic stroke. However, the role of hs-CRP levels in the functional outcomes after large-artery atherosclerosis (LAA) and small-artery occlusion (SAO) is poorly understood. METHODS:We recruited 1...

journal_title：Neurological research

authors： Hou D,Liu J,Feng R,Gao Y,Wang Y,Wu J

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of electrical stimulation (ES), stretching and their combined effects in matrix metalloproteinases (MMPs) gene expression and activity during early denervation of rat tibialis anterior (TA) muscle by axonotmesis. METHODS:Thirty adult male Wistar rats were divided into five groups: no...

journal_title：Neurological research

authors： Peviani SM,Russo TL,Durigan JL,Vieira BS,Pinheiro CM,Galassi MS,Salvini TF

更新日期：2010-10-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of the dopamine producing neurons projecting from the substantia nigra into the corpus striatum. Current medical therapy is limited and cannot stop or reverse the degeneration. Over the past 30 years, attempts were m...

journal_title：Neurological research

authors： Roitberg B,Urbaniak K,Emborg M

更新日期：2004-06-01 00:00:00

abstract：:The present study aimed to examine the effects of N omega-nitro-L-arginine (LNA) on the early ischemic neuronal damage (EIND). All the experiments were carried out under general anesthesia, maintaining the blood gases and the body temperature within the physiological ranges. The local CBF, the topographically correspo...

journal_title：Neurological research

authors： Matsui T,Nagafuji T,Mori T,Asano T

更新日期：1997-04-01 00:00:00