Comparative study among three different methods of bone marrow mesenchymal stem cell transplantation following cerebral infarction in rats.

abstract：OBJECTIVE:The aim of this study was to establish a robust set of motor tasks that could be used to functionally delineate the motor cortex with blood oxygenation level dependent functional magnetic resonance imaging (BOLD fMRI) at 3 T and produce precise functional maps for pre-operative planning and functional neurona...

journal_title：Neurological research

authors： Berntsen EM,Samuelsen P,Lagopoulos J,Rasmussen IA Jr,Håberg AK,Haraldseth O

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:To describe the role of neurosurgical techniques in treatment of symptoms of multiple sclerosis (MS). METHODS:A review of the existing world literature searching (using PubMed, August 22, 2005) for key words 'multiple sclerosis' and multiple symptoms associated with MS including trigeminal neuralgia, pain (...

journal_title：Neurological research

authors： Patwardhan RV,Minagar A,Kelley RE,Nanda A

更新日期：2006-04-01 00:00:00

abstract：:Ninety percent of cerebral aneurysms were diagnosed after their first rupture with consecutive subarachnoid haemorrhage. In order to detect the aneurysms before rupture investigation by transcranial Doppler sonography was used on the basis of intra-operative evaluation of the normal aneurysmal flow pattern. In 34 pati...

journal_title：Neurological research

authors： Gilsbach JM,Harders AG

更新日期：1989-03-01 00:00:00

abstract：OBJECTIVE:Transcranial Doppler (TCD) measures blood flow velocities (BFV) and is an indirect method of assessing cerebral blood flow (CBF). Positron emission tomography (PET) is a direct method to measure CBF. This study evaluates the correlations between TCD and PET findings Methods: Nine patients with a symptomatic c...

journal_title：Neurological research

authors： Rijbroek A,Boellaard R,Vriens EM,Lammertsma AA,Rauwerda JA

更新日期：2009-02-01 00:00:00

abstract：:Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the degeneration of the dopamine producing neurons projecting from the substantia nigra into the corpus striatum. Current medical therapy is limited and cannot stop or reverse the degeneration. Over the past 30 years, attempts were m...

journal_title：Neurological research

authors： Roitberg B,Urbaniak K,Emborg M

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Recurrent lumbar disc herniation (rLDH) is a common issue after primary discectomy and can cause severe pain, morbidity, and reoperation. The purpose of this systematic review was to evaluate the surgical management of recurrent lumbar disc herniation. METHODS:A systematic literature search was conducted usi...

journal_title：Neurological research

authors： Arif S,Brady Z,Enchev Y,Peev N

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:Our objective was to characterize the heat shock response (HSR) in a model of traumatic brain injury (TBI) and to determine the association of HSR to cell death. METHODS:We used immunofluorescent detection of HSP-70 to characterize HSR and TUNEL labeling to determine the pattern of cell death. RESULTS:HSP-...

journal_title：Neurological research

authors： DeGracia DJ,Kreipke CW,Kayali FM,Rafols JA

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:Numerous studies have demonstrated a protective effect of hyperbaric oxygen therapy in experimental ischemic brain injury, and many physiological and molecular mechanisms of hyperbaric oxygen therapy-related neuroprotection have been identified. METHODS:Review of articles pertaining to hyperbaric oxygen t...

journal_title：Neurological research

authors： Matchett GA,Martin RD,Zhang JH

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:Brain death is a clinical diagnosis often confirmed with supplementary tests. In this study, we examined the relationship between brain death and the partial pressure of brain tissue oxygen (PbtO(2)). We hypothesized that a sustained PbtO(2) of 0 is associated with brain death. METHODS:One hundred and twent...

journal_title：Neurological research

authors： Smith ML,Counelis GJ,Maloney-Wilensky E,Stiefel MF,Donley K,LeRoux PD

更新日期：2007-10-01 00:00:00

abstract：:Objectives: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). Methods: Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.5 h, 6...

journal_title：Neurological research

authors： Hao CH,Ding WX,Sun Q,Li XX,Wang WT,Zhao ZY,Tang LD

更新日期：2019-11-01 00:00:00

abstract：:The craniocervical regions of seven cadavers (14 sides) injected with silicone rubber were dissected under a Zeiss OPMI surgical microscope. The present study provides a detailed description of the suboccipital segment of the vertebral artery, with particular attention to its loops, branches, supporting osteofibrous s...

journal_title：Neurological research

authors： Castillo C,Viñas FC,Gutikhonda M,Diaz FG

更新日期：1998-04-01 00:00:00

abstract：:In this study, we examined the degree of disruption of blood-brain barrier (BBB) in irradiated rat brains using P-glycoprotein, one of the functional molecules of BBB, as a marker. In the animal experiments, disruption of BBB has been mainly studied at the acute stage of brain edema caused by a lethal dose of irradiat...

journal_title：Neurological research

authors： Mima T,Toyonaga S,Mori K,Taniguchi T,Ogawa Y

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVE:This review article summarizes in vitro, in vivo, and clinical evidence pertaining to temozolomide (TMZ) and bevacizumab (BEV) efficacy and mechanism of action in gliomas. METHODS:Relevant publications published before June 2013 in PubMed database were reviewed. RESULTS:Temozolomide and BEV are current chem...

journal_title：Neurological research

authors： Nanegrungsunk D,Onchan W,Chattipakorn N,Chattipakorn SC

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVES:Progesterone modulates dopamine (DA) release in corpus striatum. Our objective was to evaluate the effect of the i.c.v injection of the neurosteroid allopregnanolone (ALL), a progesterone metabolite on dopaminergic activity in the corpus striatum of rats under different gonadal hormonal conditions. METHODS:...

journal_title：Neurological research

authors： Laconi MR,Reggiani PC,Penissi A,Yunes R,Cabrera RJ

更新日期：2007-09-01 00:00:00

abstract：:The object of the study was to evaluate brain tissue oxygenation (p(ti)O2) for intra-operative monitoring of critical ischemic events during early cerebral aneurysm surgery of the anterior circulation supplementary to somatosensory evoked potentials (SEPs). P(ti)O2 was continuously evaluated during surgery for an intr...

journal_title：Neurological research

authors： Szelényi A,Jung CS,Schön H,Seifert V

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVES:The presence of beta-amyloid (betaA) deposition, induction of reactive gliosis and dystrophic neurites, is a characteristic feature of neuritic plaques in Alzheimer's disease. In vitro, betaA-exposed astrocytes become reactive, similar to astrocytes in contact with betaA plaques in vivo. How betaA-exposed re...

journal_title：Neurological research

authors： Monnerie H,Esquenazi S,Shashidhara S,Le Roux PD

更新日期：2005-07-01 00:00:00

abstract：:The spontaneous disappearance and reappearance of a ruptured cerebral aneurysm is generally assumed to be a rare phenomenon although the actual incidence is unknown. Among 39 consecutive cases of acute subarachnoid hemorrhage (SAH), 33 were studied by three-dimensional computed tomographic angiography (CTA) within 6 h...

journal_title：Neurological research

authors： Nakajima Y,Yoshimine T,Mori H,Nakamuta K,Fujimura I,Sakashita K,Kohmura E,Hayakawa T,Yokota J

更新日期：2000-09-01 00:00:00

abstract：:We assessed the effect of a novel calmodulin antagonist, DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) in a spontaneously hypertensive rat (SHR) permanent focal cerebral ischemia. In experiment I, the left middle cerebral ...

journal_title：Neurological research

authors： Takagi K,Sato T,Shirasaki Y,Narita K,Tamura A,Sano K

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:Interleukin-21 (IL-21) is a cytokine that is an important modulator of immune responses. However, its roles in epilepsy are not completely clear. Here, we investigated the expression and distribution of IL-21 in a kainic acid (KA)-induced acute seizure mouse model. MATERIALS AND METHODS:Mice (n = 146) were r...

journal_title：Neurological research

authors： Xiong XY,Wang TG,Yang MH,Meng ZY,Yang QW,Wang FX

更新日期：2016-02-01 00:00:00

abstract：:Supraventricular and ventricular tachyarrhythmia are established causes of syncope. We investigated the mean blood flow velocities (Vmean) of the middle cerebral arteries (MCA) during routine cardiac electrophysiologic studies in patients with supraventricular and ventricular tachyarrhythmias in order to evaluate the ...

journal_title：Neurological research

authors： Zunker P,Haase C,Borggrefe M,Georgiadis D,Georgiadis A,Ringelstein EB

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVES:Hourly neurologic assessments for traumatic brain injury (TBI) in the critical care setting are common practice but prolonged use may actually be harming patients through sleep deprivation. We reviewed practice patterns at our institution in order to gain insight into the role of frequent neurological assess...

journal_title：Neurological research

authors： Stone JJ,Childs S,Smith LE,Battin M,Papadakos PJ,Huang JH

更新日期：2014-02-01 00:00:00

abstract：:Thromboxane A2 (TXA2) is a proaggregatory vasoconstrictor that is synthesized and released during reperfusion of ischaemic brain. We administered a TXA2 receptor antagonist, SQ29,548, and a thromboxane A synthase inhibitor, 1-benzylimidazole (1-BI), to rats subjected to 30 min of reversible forebrain ischaemia. Cerebr...

journal_title：Neurological research

authors： Pettigrew LC,Hazle JD,Gutierrez G,Smith CD,Ogletree ML

更新日期：1992-09-01 00:00:00

abstract：:Acute presentation of Type I Chiari malformation in children is distinctly rare. An 11 year old male suffered a trauma to the right temporal-parietal region in a tobogganing accident resulting in an open depressed skull fracture. Radiographic evaluation included a Computed Tomographic scan which also demonstrated a si...

journal_title：Neurological research

authors： Couldwell WT,Zhang W,Allen R,Arce D,Stillerman CB

更新日期：1998-01-01 00:00:00

abstract：:Using magnetic resonance imaging, we reviewed 141 infratentorial infarcts in 81 consecutive cases: 65 infarcts were seen in the paramedian pons, while 18 in the posterior inferior cerebellar artery (PICA) territory and 17 in the watershed area between PICA and superior cerebellar artery. No comparable sign or symptom ...

journal_title：Neurological research

authors： Yin WM,Nagata K,Satoh Y,Yokoyama E,Watahiki Y,Yuya H,Hirata Y,Ogawa T,Inugami A

更新日期：1994-06-01 00:00:00

abstract：:We describe the use of optical spectroscopy in the near infra-red light range to non-invasively measure regional cerebral haemoglobin oxygen saturation (rSHbO2) in cats during progressive cerebral hypoxia. This technique differs from spectroscopic techniques previously described in that the concentration ratio--percen...

journal_title：Neurological research

authors： McCormick PW,Stewart M,Ray P,Lewis G,Dujovny M,Ausman JI

更新日期：1991-03-01 00:00:00

abstract：:In order to evaluate the relationship between brain oxygen supply and demand (O2 balance) in real time, it is necessary to use a multiparametric monitoring approach. Cerebral blood flow (CBF) is a representative parameter of O2 supply. The extracellular level of K+ is a reliable indicator of O2 demand since more than ...

journal_title：Neurological research

authors： Mayevsky A,Meilin S,Manor T,Ornstein E,Zarchin N,Sonn J

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:This study examined whether a needle-free acupuncture can be an alternative to conventional needle injection acupuncture. METHODS:Patients (n=101) suffering myofascial shoulder pain were randomly assigned to either needle-free or conventional needle injection acupuncture group. Bee venom was administered int...

journal_title：Neurological research

authors： An K,Kim YS,Kim HY,Lee H,Hahm DH,Lee KS,Kang SK

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:In the present study, we investigated the effects of treadmill exercise on microglial activation and the subsequent release of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6 and IL-1-beta in the hippocampus in a rat model of type 2 diabetes. METHODS:At 30 weeks of age, diabetic (Zucker diabeti...

journal_title：Neurological research

authors： Yoo DY,Chae J,Jung HY,Yim HS,Kim JW,Nam SM,Kim DW,Choi JH,Seong JK,Yoon YS,Hwang IK

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Diffusion tensor tractography (DTT) has recently been shown to accurately detect nerve injury and regeneration. This study assesses whether 7-tesla (7T) DTT imaging is a viable modality to observe axonal outgrowth in a 4 cm rabbit sciatic nerve injury model fixed by a reverse autograft (RA) surgical techniqu...

journal_title：Neurological research

authors： Farinas AF,Pollins AC,Stephanides M,O'Neill D,Al-Kassis S,Esteve IVM,Colazo JM,Keller PR,Rankin T,Wormer BA,Kaoutzanis C,Dortch RD,Thayer WP

更新日期：2019-03-01 00:00:00

abstract：:Two hundred and sixty-one neurologically asymptomatic patients were examined by computed tomography (CT) following a variable number of transient ischaemic attacks (TIAs) experienced over different time intervals. Cerebral infarcts were discovered in 101 patients. Dominant hemisphere infarcts were usually small, of re...

journal_title：Neurological research

authors： Turnbull IW,Bannister CM

更新日期：1985-12-01 00:00:00